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Memory is a vital biological system in the body that plays a role in storing, processing, and recalling information. Over time, due to aging or external factors, memory function may decline. One possible effort to maintain and improve cognitive performance is through the use of bioactive compounds with antioxidant properties. Avocado (Persea americana Mill.) leaves contain flavonoids, which act as antioxidants and possess neuroprotective effects that may enhance cognitive function, including memory. This study aimed to determine the effect of avocado leaf extract on the memory of male mice and to identify the most effective dose in improving cognitive performance. The extract was obtained using the maceration method with 70% ethanol as the solvent. Memory activity was tested on male mice, which were divided into five groups: negative control, positive control, and three treatment groups given avocado leaf extract at doses of 50, 100, and 200 mg/kgBW. The Y-Maze method was employed to assess memory through two parameters: latency time and error numbers. The results demonstrated that avocado leaf extract significantly improved memory in the test animals. Mice induced with 10% ethanol showed an increase in latency time and error numbers, while the groups treated with avocado leaf extract experienced reductions in both parameters. The most effective dose was 200 mg/kgBW, which produced a latency time difference of 19.5 seconds and an error number difference of 3.57. Therefore, avocado leaf extract shows potential as a natural agent to support and enhance cognitive function.

Nephrolithiasis, commonly known as kidney stone disease, can be experimentally induced in animal models using ethylene glycol (EG) in combination with ammonium chloride, which closely mimics calcium oxalate stone formation in humans. This condition is associated with significant renal tissue injury, including glomerular atrophy, tubular necrosis, and hyaline droplet accumulation, ultimately impairing kidney function. The present study aimed to investigate the histopathological changes in the kidneys of EG-induced rats and evaluate the nephroprotective potential of combined avocado (Persea americana) and gooseberry (Physalis angulata) leaf extracts. A total of 30 male Sprague Dawley rats were randomly divided into five groups: a standard control (no induction), a negative control (EG-induced without treatment), a positive control (EG-induced and treated with a commercial nephroprotective agent), and two treatment groups receiving the combined extracts at different doses. Nephrolithiasis induction was performed over 28 days, followed by oral administration of the respective treatments. At the end of the experiment, kidney tissues were collected and processed for histological examination using hematoxylin-eosin staining to assess the extent of tissue damage. The negative control group exhibited the most severe histopathological alterations, with hyaline droplet formation reaching 15.0 ± 5.25%. In contrast, extract-treated groups demonstrated a marked reduction in tissue damage, with the most significant improvement observed in the group receiving 300 mg/kg avocado extract and 100 mg/kg gooseberry extract, which recorded hyaline droplet formation of only 5.27 ± 2.74%, a result comparable to that of the standard control group. These findings suggest that the combination of P. americana and P. angulata leaf extracts confers protective effects against EG-induced renal injury. Therefore, this herbal combination may represent a promising natural nephroprotective agent that warrants further investigation in preclinical and clinical settings.

Diversification of agricultural products is one strategy to increase the added value and competitiveness of local commodities. Avocado (Persea americana) is a tropical fruit that is rich in nutrients, such as healthy fats, fiber, vitamins and minerals. However, the use of avocados in Indonesia is still limited to fresh consumption and simple processing. This research aims to develop an innovative product in the form of avocado-based sponge cake as an effort to diversify agricultural products. The method used includes organoleptic testing. The research results show that the use of avocado in making sponge cake can improve the soft texture, distinctive aroma, color and unique taste. Organoleptic tests show a good level of consumer acceptance with an average score of above 50% in the aspects of taste, color and texture. Apart from that, nutritional analysis shows that avocado cake has a higher content of healthy fats and fiber than conventional cake. Implementation of this product has the potential to open up new market opportunities and provide added value for local avocado farmers.

Vegetative propagation is a crucial technique in horticultural cultivation aimed at improving plant quality and productivity. This study explores budding in citrus (Citrus spp.) and grafting in avocado (Persea americana Mill.) as methods of plant propagation. Budding involves attaching buds from superior varieties to compatible rootstocks, whereas grafting unites scions and rootstocks to obtain desirable traits. The research was conducted at the Horticulture Seed Center, observing the growth and success of plant unions. The results demonstrate that both techniques effectively enhance plant quality, with budding showing faster results in citrus and grafting improving avocado resilience to environmental conditions. This study provides guidance for farmers to select optimal propagation methods tailored to their plants' specific needs.

Mekarbuana Village located in Tegalwaru, Karawang district, West Java, is about 45 kilometers from the center of Karawang, and has potential for agro-tourism and natural tourism, because according to the village head, Jaji Maryono, the village is a provider of coffee, durian, mango, avocado, and bananas. The tourism  that are available are Curug Cigentis, Curug Bandung, and tours along the flow of the river. This tourist destination is a favourite destination of both locals and citizens around Karawang to spend the weekend with the family. Due to the tourist potential in his village, the village chief acknowledged that he wanted to bring Mekarbuana Village  into a tourist village, but still needed support and enhanced human resource capacity (HRM) to manage the village. The problem is that the tourism organization in the village are not functioning, so the wheel of tourism in that village is still not balanced. This activity uses methods of accompaniment, socialization, and education carried out in integration with KKN students to the community and tourists in Mekarbuana Village. The result of this community service activity is the reactivation of the pokdarwis management, the existence of the organization structure, the presence of the work plan, a varied tour package, as well as the Mekarbuana Village  already registered in the JADESTA. As to the conclusion of the activities, they feel very grateful and hoped that the organization will be able to maximize its management, and continue to run consistently and professionally in managing tourism in the village.

Dysmenorrhea is menstrual pain that occurs in the lower abdomen and spreads to the back, waist, pelvis, upper thighs, and calves. The cause of dysmenorrhea is an increase in prostaglandin levels so that the contractility of the uterine muscle is ischemic as a result of the vasoconstrictive effect produced by prostaglandins. According to data from the World Health Organization (WHO) the prevalence of dysmenorrhea in adolescents is 90% consisting of  75% -80% primary dysmenorrhea and 10% - 15% experiencing secondary dysmenorrhea, while data from the Association of Southeast Asian Nations (ASEAN) prevalence of primary dysmenorrhea in Malaysia (69.4%), Thailand (84.2%), and Indonesia (65%). The prevalence of dysmenorrhea in Indonesia in 2018 was 64.25% consisting of 54.89% primary dysmenorrhea and 9.36% secondary dysmenorrhea. This study aims to determine the effectiveness of administering avocado juice (Persea americana Mill) on reducing the rate of primary dysmenorrhea in first-level students of applied undergraduate study programs at the Indonesian Ministry of Health Polytechnic in Medan in 2023.The type of research used was Quasi Experiment with One Group Pretest and Posttest design. The sample in the study amounted to 30 people. The results of the research on the experimental group obtained a decrease in menstrual pain scale with an average of 2.66. The results of the analysis using the Wilcoxon test with a 95% level of confidence show a Sig (2-tailed) value of <0.05, which means that there is an effect of giving avocado juice on a decrease in primary dysmenorrhea in first level female students of the Bachelor of Applied Midwifery Study Program, Poltekkes Kemenkes Medan in 2023. It is expected that Poltekkes Kemenkes Medan to be able to utilize avocado fruit which is processed into juice in reducing menstrual pain in female students and for future researchers to be able to use my thesis as a reference.

This study aims to evaluate the effect of grafting and budding techniques on the growth and success of avocado (Persea americana) plant propagation. Grafting and budding techniques are vegetative methods commonly used in horticultural plant propagation to maintain the genetic quality of the parent plant. The study was conducted using avocado plants with grafting and budding techniques on the rootstock. The parameters observed included the level of success of unification (compatibility rate), shoot growth rate, survival percentage, and growth in stem diameter and plant height during a certain period. The results showed that the grafting technique provided a higher success rate than the budding technique on certain varieties, with a survival percentage reaching 85%. However, the budding technique showed advantages in the parameter of shoot growth rate, especially on varieties with specific or better environmental adaptation. This study shows that choosing the right propagation technique, depending on the characteristics of the variety and environmental conditions, is a key factor in supporting the success of avocado plant propagation. These findings are expected to be a reference for farmers and researchers in optimizing the production of high-quality avocado seedlings.

The rapid development of the industry has driven the emergence of various technologies that can support the industry, especially in production activities. Production activities are the actions performed by humans to generate a product, be it goods or services, which are then utilized by consumers. These activities operate around the clock to produce products that meet market demand. For smooth production activities, manufacturing industries need to provide raw materials that meet targets and create plans before operating, with inventory levels set to ensure that needs are met in terms of quality, quantity, time, and low cost as planned. PT XYZ is a fruit juice manufacturer with avocado juice being its most popular product. The production of avocado juice was analyzed over the period of 2015-2020 using Vensim software with four scenarios to assess the availability of raw materials. The research findings reveal that the total availability of flour raw materials in 2020 was 10,000 tons; 9,450 tons; 9,500 tons; 10,150 tons; 11,400 tons; 13,250 tons. To address the issue, PT XYZ can monitor fruit stocks and periodically estimate fruit seasons.    

This study explores the use of natural dyes as an environmentally friendly alternative to synthetic dyes for coloring batik fabric. Specifically, the researchers focus on developing natural dyes from a combination of avocado leaves and soursop leaves. The study aims to determine the impact of extraction time and the ratio of avocado and soursop leaves on the color fastness of batik cloth. Experimental methods were employed, with two extraction times (120 and 240 minutes) and three ratios of raw materials (25%:25%, 15%:35%, and 35%:15%) tested. The results of the color fastness test, which assessed washing and rubbing, demonstrated that the mixture of avocado and soursop leaves exhibited good fastness and resistance to rubbing. These findings suggest that the extracted mixture could be used effectively as a natural dye for batik fabric. Overall, this study contributes to the development of eco-friendly alternatives for the dyeing process in batik production.

Avocado is a climacteric fruit, which is usually harvested when it is still unripe. One way to accelerate the maturity of climacteric fruit is by ripening. Ripening treatment with ethrel can accelerate fruit ripening. This study aims to determine the effect of proper ethrel concentration on the avocado ripening process. The experimental design used was RAL (Completely Randomized Design) 1 Factor with 5 treatments and 4 replications. The treatment consisted of P0 control without ethrel treatment, then added ethrel solution P1 = 0.25 ml/L, P2 = 0.50 ml/L, P3 = 0.75 ml/L and P4 = 1.00 ml/L. Variables observed included weight loss, color, texture/hardness, water content, total dissolved solids and fat content. The data obtained were analyzed for variance and if there were significant differences in the treatment then it was further tested with Duncan's test at the 5% level. Based on the results of research on adding the right ethrel solution to the avocado ripening process found in P4 with the addition of 1.00 ml/L ethrel with a fat content of 15.34%, water content 88.99%, total dissolved solids 2.10 mg/L, texture 968.85grf, color 80.44 and weight loss 10.51%.

Buter Balik Village, Kute Panang District, located in Central Aceh District, has fertile land and the majority of the people are farmers. Buter Balik Village has several community livelihoods, including coffee, chili, avocado, sugarcane, and so on. Most of the people in the village have sugarcane plantations on average. The community cultivates their own sugarcane plantations without depending on other people or outside the area. The community also processes the sugarcane plants themselves into processed products in the form of brown sugar. The method used in this article is descriptive qualitative. The purpose of this observation is to find out the process of making brown sugar from sugarcane in Buter Balik Village. The results of the observations have concluded that brown sugar from sugar cane juice has several benefits including preventing fatigue, meeting the body's mineral needs, maintaining bone health, and there are many benefits to be gained from brown sugar.

Along with the growing public awareness of personal and environmental health, lipa sabbe products with natural colors are increasingly popular. Natural dyes are advantageous because they do not need to be imported, are safe for human health during the manufacturing process, do not pollute the environment, and are safe. Although synthetic dyes are easier to use, they are harmful to health, produce hazardous waste, pollute the environment, and are made from imported materials. This study aims to determine the types of plants that can be used as natural dyes for lipa sabbe. Qualitative methods with literature studies sourced from journals, books, or other related scientific articles are used in this research. The results showed that natural dyes in lipa sabbe became one of the Science Learning Resources with natural dyes including extracts from cocoa shell waste, coconut fiber waste, oil palm shell waste, rambutan peel waste, mangosteen peel waste, guava leaf waste, mango leaf waste and avocado leaf waste is plantation waste that can be used as a natural lipa sabbe dye. The pigments in this material produce yellow, reddish brown, gray, and black colors.   Keywords: , ,.