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This research focuses on the synthesis and characterization of the double salt copper(II) ammonium sulfate hexahydrate, Cu(NH4)2(SO4)2·6H2O. The study aims to obtain the compound in crystalline form and evaluate its properties through yield calculation, solubility testing, and Fourier Transform Infrared (FTIR) spectroscopy. The synthesis involved reacting copper(II) sulfate pentahydrate (CuSO4·5H2O) with ammonium sulfate ((NH4)2SO4) under controlled conditions, followed by crystallization. The process produced 10.84 grams of crystalline Cu(NH4)2(SO4)2·6H2O with an 86.23% yield, indicating efficient synthesis. Solubility tests showed that the crystals were polar, soluble in polar solvents like water and hydrochloric acid (HCl), partially soluble in ammonium hydroxide (NH4OH), and insoluble in less polar solvents like ethanol and chloroform (CHCl3). FTIR analysis confirmed the presence of functional groups such as O–H, N–H, and S–O stretching vibrations, supporting the proposed molecular structure. The findings demonstrate that Cu(NH4)2(SO4)2·6H2O can be efficiently synthesized, and its physicochemical properties align with theoretical expectations. This study contributes to the understanding of double salt synthesis and characterization, relevant for inorganic chemistry, material science, and potential applications in catalysis and coordination chemistry.

The use of medicinal plants as herbal beverages has long been a part of Indonesian culture. However, the less preferred taste and aroma are obstacles to consumer acceptance. Cat's Whiskers leaves (Orthosiphon aristatus) are known to contain bioactive compounds that act as antioxidants, while Key Lime leaves (Citrus aurantifolia) have a fresh aroma and functional properties that can enhance flavor and health benefits. This study aims to evaluate the effect of adding Key Lime leaves (Citrus aurantifolia) on the chemical characteristics, sensory properties, and effectiveness of brewed Cat's Whiskers (Orthosiphon aristatus) leaf beverages.Five formulations with varying concentrations of Key Lime leaves (0%, 5%, 10%, 15%, and 20%) were tested based on the parameters of moisture content, ash content, pH, solubility, antioxidant activity, and organoleptic tests including color, aroma, taste, and texture. The results showed that the addition of Key Lime leaves significantly improved the chemical quality and sensory acceptability, with the best formulation obtained in treatment P4 (20% Key Lime leaves + 15g Cat's Whiskers), which provided an optimal balance between stability, nutritional content, and organoleptic quality. The addition of Key Lime leaves is recommended as an innovation in the development of functional herbal beverages based on Cat's Whiskers.

The selection of appropriate solvents in sterile injection formulations plays a pivotal role in determining the stability, efficacy, and safety of pharmaceutical products. Among the commonly utilized solvents, Dimethyl Sulfoxide (DMSO), Polyethylene Glycol (PEG), and pyrogen-free water exhibit distinct physicochemical properties and functional roles. This study aims to analyze the characteristics, functions, and implications of these three solvents within the context of sterile injectable preparations. The research methodology involves a comprehensive review of six peer-reviewed scientific articles published within the last five years, focusing on solvent performance, compatibility, and safety profiles. Findings reveal that DMSO is highly effective in dissolving lipophilic compounds due to its strong solvating capacity. However, its use at elevated concentrations may lead to irritation and cytotoxicity, necessitating careful dosage regulation. PEG, particularly in its flexible molecular weight variants, serves as a co-solvent and viscosity modifier, enhancing solubility and stability of active pharmaceutical ingredients. Pyrogen-free water, characterized by its inertness and biocompatibility, remains the gold standard for injection solvents, offering minimal risk and broad applicability across drug classes. The study underscores the importance of aligning solvent selection with the physicochemical nature of the drug, intended route of administration, and patient safety considerations. Furthermore, the potential for combining solvents to achieve optimized formulations is highlighted as a promising avenue for future pharmaceutical development. Such combinations may offer enhanced solubility, reduced toxicity, and improved delivery mechanisms, particularly for complex or poorly soluble compounds. In conclusion, understanding the nuanced roles of DMSO, PEG, and pyrogen-free water is essential for formulating safe and effective sterile injections. This research contributes to the growing body of knowledge supporting rational solvent selection and encourages further exploration into innovative solvent systems for advanced drug delivery.

Physical modification of starch using microwave heat treatment (MHT) technology serves as an efficient and environmentally friendly alternative to enhance the functional properties of starch without chemical additives. This article aims to examine the influence of microwave power and heating duration on the swelling power and solubility of various starch types, including tapioca, taro, sago, and lotus rhizome. A review of four studies revealed that power and time parameters significantly affect the crystalline structure of starch granules, resulting in either enhancement or reduction of their functional properties. High power or prolonged heating may decrease swelling power due to crystal restructuring and granule disruption, while solubility increases as a result of amylose and amylopectin degradation. MHT has proven to accelerate the heating process in a volumetric and efficient manner, improving water absorption capacity and viscosity. Despite its drawback of uneven heat distribution, this method remains relevant as a physical modification technique aligned with green processing principles in the food industry.

Nanomaterials have a variety of uniqueness and attractiveness, it is considered necessary to carry out literature study, beside the laboratory investigation, among others, on the nanoparticle structure and energy gap of ZnO nanoparticles doped with aluminum (Al) resulting from synthesis using various methods. In this study, the structure of the nanoparticles was divided into three types, namely crystal structure, crystallite size, and morphology. The crystal structure of the Al doped ZnO nanoparticles is hexagonal wurtzite. It is found, that, a decrease in crystallite size occurs as the doping of Al into ZnO increases to its solubility limit. A similar pattern also occurs in particle size. The high concentration of Al doping results in agglomeration. The morphology of Al doped ZnO nanoparticles in some references of this study are rod, spherical, and irregular spheres. The energy gap value of Al doped ZnO nanoparticles increases with the increasing concentration of Al doping in ZnO. So, it can be said, that Al as a doping material has an influence on the structure and optical properties of ZnO nanoparticles.