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This study investigates the pivotal role played by the Regional Health Office of North Sulawesi Province in managing the COVID-19 patient referral system. The COVID-19 pandemic has placed immense pressure on healthcare systems worldwide, necessitating efficient coordination and management of patient referrals to ensure timely and appropriate care. The Regional Health Office of North Sulawesi Province plays a critical role in overseeing and optimizing the patient referral process, which includes triage, transportation, and coordination among healthcare facilities. This research aims to analyze the effectiveness and challenges faced by the Regional Health Office in managing COVID-19 patient referrals, with a focus on improving the overall healthcare response to the pandemic.

The success of stroke treatment is determined by the speed and accuracy of treatment. The golden time in treating stroke is ± 3 hours. Integrated Referral System SISRUTE is a tool that facilitates the transfer of health services between various health facilities.Rapid reporting through the web application is facilitated by this system.. The aim of this research is the relationship between the use of an integrated referral system (SISRUTE) and the speed of success in emergency treatment of stroke cases in the0AGD0of the0DKI0Jakarta0Health Office. The research method that will be used is an analytical research design with a correlational The design was cross-sectional, with a population of 340 participants and 77 participants chosen for the sample size. Using the parametric Chi-Square test. The results show a relationship between using the integrated road system (SISRUTE)..and the success rate of speed of emergency treatment of stroke cases in the0AGD0of the0DKI0Jakarta Health0Office0with a p-vlue of 0.014 < 0.05. Conclusion: The use of an integrated referral system can influence the success rate of stroke emergency treatment.