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Diabetes mellitus (DM) is one of the global health challenges that continues to rise, including in Indonesia. However, the lack of education and counseling from pharmacists regarding the use of natural ingredients medicines has the potential to affect the effectiveness of treatment and the management of DM. This study aims to measure the level of knowledge, attitudes, and behaviour of DM patients, related to the use of natural ingredient drugs in DM management. This study uses a cross-sectional method design, starting with the collection of quantitative data. Sampling was conducted using purposive sampling technique over a period of four months. The research involved 101 DM patients from 15 pharmacies in Kendal Regency. The level of knowledge (44.6%), attitude (66.3%), and behaviour (39.6%) of patients in the moderate category. However, the limited knowledge of pharmacists remains a barrier to optimizing pharmaceutical services related to educating patients about natural ingredient medications.

This research investigates the application of the Economic Order Quantity (EOQ) method to improve drug inventory management in a primary hospital pharmacy, with a particular focus on reducing storage costs. A descriptive quantitative approach was applied using secondary data from January to December 2024, covering annual demand, purchase price, ordering cost, and holding cost. The analysis concentrated on fast-moving vital essential and moderate vital drugs that are critical for sustaining patient treatment. The study revealed inefficiencies in the hospital's procurement practices, with some medicines simultaneously facing overstock and stockout risks, indicating weak planning. EOQ calculations provided alternative procurement quantities that were smaller but more frequent, resulting in lower storage costs and better stock control. Simulation outcomes demonstrated notable cost savings, particularly for Flamicort, Diazepam, and Ventolin. These findings emphasize the value of integrating EOQ into hospital pharmaceutical logistics to reduce financial losses, strengthen supply chain efficiency, and ensure the continuous availability of essential medicines in primary hospital settings.

The revocation of Pinkflash's cosmetic product distribution license by the Food and Drug Supervisory Agency (BPOM) has once again attracted public attention after the brand experienced a similar incident in 2024. This crisis raises questions about Pinkflash's public relations strategy in maintaining consumer trust and preserving its brand reputation. This study aims to analyze Pinkflash's public relations strategy and measure the impact of the crisis on public perception through social media sentiment analysis using Brand24. The research method used is a descriptive qualitative approach. The main data in this study was obtained from official documents by BPOM and official brand statements, which were then analyzed using content analysis and sentiment analysis using Brand24. The results of the study show that Pinkflash's crisis response only temporarily dampened negative sentiment. The root of the problem lies in weak governance, which led this study to conclude that reputation can only be rebuilt through comprehensive improvements to the quality of its systems and supply chain, with a commitment to honest operations as the key.

This study evaluated drug inventory management in a primary hospital pharmacy using the Economic Order Quantity (EOQ) method. A descriptive quantitative design was applied with secondary data collected from January to December 2024, covering annual demand, purchase price, ordering cost, and holding cost. The analysis revealed inefficiencies, as several drugs simultaneously faced overstock and stock out risks, indicating weaknesses in procurement planning. EOQ calculations suggested lower and more frequent procurement, reducing storage costs and improving stock control. The findings demonstrated that applying EOQ could minimize financial risks, optimize resource allocation, and ensure continuous access to essential medicines. This research highlights the relevance of structured inventory models in supporting hospital efficiency and sustainable pharmaceutical logistics, particularly in resource-limited primary hospitals.

The implementation of the Frequent Pattern Growth (FPG) algorithm in a web-based drug purchasing application at Sumber Sehat Pharmacy aims to improve efficiency and accuracy in analyzing customer drug purchasing patterns. The FPG algorithm is a method used to identify frequent purchase patterns or frequent itemsets in purchase transactions, which can then be used to make relevant drug recommendations for customers. This study uses a case study at Sumber Sehat Pharmacy to explore drug purchasing patterns and provide a data-driven solution that can help pharmacies improve service and adjust drug stocks according to customer needs. The results show that the application of the FPG algorithm can identify significant purchasing patterns and assist pharmacies in determining more appropriate promotional strategies and inventory management. By using a web-based application that implements this algorithm, Sumber Sehat Pharmacy can provide drug recommendations that are more in line with customer preferences, thereby increasing customer satisfaction and pharmacy operational efficiency.

Drug stock-outs are an indicator of pharmaceutical management failure that directly affects patient safety and the quality of hospital services. Gatoel Hospital Mojokerto experienced an increase in the percentage of drug debt from 3.14% in January to 6.20% in July 2025, with 1,607 patients affected. This study aims to identify the factors causing drug stock-outs and formulate preventive strategies through the optimization of the Minimum-Maximum Stock Level (MMSL) system based on the Hospital Information System. A mixed-method approach was used, combining secondary data analysis (January–July 2025) and in-depth interviews. Fishbone analysis was applied to identify root causes, USG analysis to determine priorities, and SWOT analysis to formulate intervention strategies. Priority drug classification was carried out using the ABC-VEN method. The intervention involved implementing an MMSL pilot project for 150 drug items under Pareto category A. The analysis identified six dimensions of stock-out causes: man, materials, methods, machines, measurement, and environment. The highest priority issue was drug demand forecasting based on historical data (USG score: 125). SWOT analysis placed the organization in quadrant II, recommending a Weakness-Opportunities (WO) strategy. MMSL implementation was initiated through the development of SOPs and the entry of 150 priority drug items into the system. Drug stock-outs are caused by multifactorial issues that require systemic intervention. MMSL optimization has the potential to serve as a long-term solution, provided there is expanded coverage, strengthened human resource capacity, and comprehensive system integration.

Introduction: The increase in life expectancy among the elderly has directly contributed to the rise in the global elderly population. According to global data, the number of elderly individuals is projected to reach 1.4 billion by 2030. This demographic growth is often accompanied by various health problems associated with aging, such as the decline in vital organ function and the emergence of degenerative diseases. One of the most common degenerative diseases among the elderly is hypertension. Hypertension is widely known as a “silent killer” because it can lead to serious complications, including stroke and heart disease, if not managed properly. A common complaint experienced by individuals with hypertension is headache, particularly in the posterior region, which significantly affects the patient’s quality of life. Management of hypertension can be carried out through pharmacological therapy with antihypertensive drugs as well as non-pharmacological interventions. One of the non-pharmacological approaches increasingly being applied is isometric handgrip exercise, which involves static muscle contractions performed at light to moderate intensity. Method:This study aimed to evaluate the effect of isometric handgrip exercise on pain reduction in patients with hypertension. The research design employed a descriptive case study involving one individual with hypertension who experienced pain complaints. The study was conducted on September 16–18, 2024, at Roujin Home X. The instruments used included observation, interview, and the provision of isometric handgrip exercise therapy. Pain measurement was carried out using a numerical rating scale before and after the intervention. Results:The three-day intervention demonstrated a significant reduction in pain levels. On the first day, the patient reported a pain score of 6, which decreased to 4 on the second day, and further declined to 2 on the third day after the intervention. Conclusion:The findings of this study indicate that isometric handgrip exercise is an effective non-pharmacological method for alleviating acute pain in patients with hypertension. This simple intervention has the potential to be applied as a complementary therapy in elderly care facilities to improve the quality of life of individuals living with hypertension.

Type 2 Diabetes Mellitus (T2DM) is a chronic condition that requires optimal adherence to pharmacological treatment to prevent disease progression and complications. This study aims to analyze the level of adherence to anti-diabetic medication among T2DM patients and to explore the association between the experience of medication side effects and adherence levels. A descriptive-analytic cross-sectional design was employed, involving 97 T2DM patients in Bandung Regency and Bandung City, Indonesia. Data were collected through structured questionnaires and analyzed using descriptive statistics and the Chi-Square test. The results revealed that 53.6% of respondents exhibited low medication adherence. The majority reported having diabetes-related complications (88.7%) and experiencing medication side effects (57.7%). A significant positive association was found between medication side effects and adherence level (p = 0.039), indicating that patients who experienced side effects tended to be more adherent. Demographic factors such as place of residence, gender, and age showed no significant association with adherence. The findings suggest that side effects may hinder adherence; however, awareness of the body’s response to medication, including side effects, may also serve as a motivator for adherence.

Dysmenorrhea, or menstrual pain, is a common gynecological problem among adolescent girls and often interferes with their daily activities, school performance, and overall quality of life. Conventional pharmacological treatments such as nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used but may cause side effects with long-term consumption. Therefore, safe and natural alternatives are needed to manage menstrual pain effectively. Carrot juice, which is rich in beta-carotene, vitamin E, and other antioxidants, has been reported to possess anti-inflammatory and analgesic properties that could potentially reduce the severity of dysmenorrhea. This study aimed to determine the effect of carrot juice on reducing menstrual pain in female students at SMAN 1 Trimurjo. A pre-experimental study with a one-group pretest–posttest design was conducted involving 27 students who experienced dysmenorrhea. Pain intensity was assessed before and after the intervention using the Numeric Rating Scale (NRS). Data were analyzed using the Wilcoxon signed-rank test. The results showed that before the intervention, the majority of respondents (85.2%) reported moderate pain, while after consuming carrot juice, 92.6% reported mild pain and 7.4% reported no pain. Statistical analysis revealed a significant difference in pain levels before and after the intervention (p = 0.000, p < 0.05). These findings indicate that carrot juice is effective in reducing dysmenorrhea intensity among adolescent girls. As a safe, affordable, and easy-to-implement non-pharmacological therapy, carrot juice has the potential to be recommended as a complementary approach to menstrual pain management, especially for adolescents who seek natural remedies. Further research with larger samples and control groups is recommended to strengthen the evidence and explore the long-term benefits of carrot juice in menstrual health.

Introduction the management of expired drugs is an important part of the hospital's pharmaceutical logistics system to ensure the safety of patients, staff, and to protect the environment. The purpose of this study is to evaluate the implementation of procedures for returning expired drugs to the manufacturer or pharmaceutical company, as well as to examine the expired drug disposal system, particularly the methods of direct disposal to the Final Disposal Site (TPA) and open burning at RSUD Mohammad Natsir Solok. However, the implementation in the field has not been entirely effective. The method used in this study is a qualitative descriptive approach, with data collection techniques including observation, interviews, and documentation. The approach involved several informants who were directly involved in pharmaceutical logistics management in order to obtain in-depth and relevant data. The results of the study show that the hospital has not carried out expired drug destruction using the methods of direct disposal to the TPA or open burning. No clear information or official documentation was found regarding the use of these two methods. Informants stated that even if such methods were used, they occurred in the past and were not formally documented. The conclusion of this study is that open burning and direct disposal to the TPA have not become part of the expired drug management system at RSUD Mohammad Natsir Solok. The recommendation of this research is the development of clear operational procedures and increased staff awareness regarding the importance of safe and standard-compliant pharmaceutical waste managemen

Efficient drug inventory management is a critical factor in ensuring medicine availability and optimizing procurement budgets in healthcare facilities. This study aims to analyze drug inventory at Tritya Eye Clinic Surabaya using the ABC (Always, Better, Control), VEN (Vital, Essential, Non-Essential), and EOQ (Economic Order Quantity) methods to improve procurement budget efficiency. A quantitative descriptive approach with a case study method was employed. Data were collected from drug usage records, stock opname reports, and procurement documents from in 2024. The findings reveal that the combined ABC-VEN method effectively identifies priority drug groups based on consumption value and clinical importance, while the EOQ method determines optimal ordering quantities to minimize total inventory costs. The integrated application of these methods successfully reduces overstock and stockout incidents and enhances procurement budget efficiency. This study recommends inventory management based on historical usage data and strategic classification to achieve more accurate and cost-effective drug procurement planning.

Digital developments in the financing system for issuing Drug Examination Result Certificates (SKHPN) have had a significant impact on improving administrative governance in the health and legal sectors in Indonesia. This study uses an empirical legal approach with a juridical-sociological method to analyze the use of information technology in payment mechanisms and governance of SKHPN services. Data were collected through in-depth interviews, direct observation, questionnaire distribution, and studies of regulations, including Law Number 17 of 2023 concerning Health and Government Regulation Number 28 of 2024. The findings show that the digitalization process of financing has a positive impact on shortening bureaucratic channels, accelerating service verification, and encouraging budget transparency and accountability. The implementation of an integrated health information system as regulated in Articles 371 to 378 of Law Number 17 of 2023 also strengthens service management through real-time and traceable digital recording. Meanwhile, PP No. 28 of 2024 emphasizes the importance of using electronic payment systems, transparency of financial reporting, and public involvement in service supervision. Although there are still obstacles such as limited infrastructure and low digital literacy, digitalization in SKHPN financing has proven to be a strategic step in realizing adaptive, open and inclusive public services in accordance with the direction of technology-based health policies.

Type 2 diabetes mellitus is a degenerative disease characterized by increased blood sugar levels due to insulin resistance. Many studies have examined the synergistic effect of nutraceutical supplementation to increase the effectiveness of drug therapy, one of which is resveratrol. However, studies that identify the effect of resveratrol on reducing HbA1c levels in patients with type 2 diabetes mellitus still have many inconsistencies in the reported results. The significance of these effects is based on the dose and timing of the particular intervention. Therefore, a literature review of several studies was carried out to assess the impact of resveratrol in treating type 2 diabetes mellitus through the HbA1c parameter and to explain the appropriate dose and duration of intervention. Articles included in the inclusion criteria are available in English and published within the last 10 years (2014-2024) in electronic databases such as PubMed-Medline, ScienceDirect, and SpringerLink. A literature review was conducted on experimental studies with type 2 diabetes patient subjects. The results of the literature review show that the recommended dose and duration that have the greatest significance in reducing HbA1c are at a dose of 200–500 mg/day for 6 months or >500 mg/day within 3 months. These results provide evidence that the adjusted dose and duration of resveratrol supplementation are very beneficial for the management of patients with type 2 diabetes mellitus.

Diabetes mellitus is a condition of elevated blood glucose levels due to impaired insulin secretion, insulin resistance, or both. This disease can lead to various serious complications that impact quality of life if not properly managed. Current diabetes management generally involves dietary modification, physical activity, and antidiabetic drug therapy. However, recent research has revealed the potential of bioactive compounds from natural sources such as curcumin in minimizing the risk of diabetes-related complications. This literature review examines and analyzes research evidence on the effects of curcumin supplementation on health parameters in patients with diabetes mellitus. The review was conducted on English-language publications in the last 10 years (2014-2024) using electronic databases. The reviewed experimental and cohort studies demonstrate the influence and beneficial effects of curcumin on glycemic control, lipid profile, weight reduction, and kidney function protection in diabetic patients. Curcumin has the potential to contribute to reducing oxidative stress and inflammation as the main triggering factors for complications of diabetes mellitus.

Health service management has an important role in managing resources effectively and efficiently, dealing with the dynamics of community needs, and ensuring quality health services through a systematic and humanistic approach. However, there are still shortcomings in the availability of adequate resources and managerial skills of implementing officers in service units that do not meet the standards. This study aims to analyze the direct impact of health management on accessibility, quality, effectiveness, and policy-making in health services.This study uses a literature review method with data sources obtained from Google Scholar, National Library e-Resources, and Garuda Portal. The research data was taken from 2015-2025. Based on the literature review, effective health management includes strategic planning, strengthening internal management, managing human resources, community involvement, and utilizing technology. The implementation of health management is proven to improve the competence of health workers, accelerate service processes, and increase patient satisfaction. In addition, good health management also encourages the expansion of health facility distribution, maintains the availability of drugs and medical devices, and improves the quality of infrastructure. However, there are challenges that need to be overcome, such as limited human resources and challenges in implementing Electronic Medical Records (EMR) in various healthcare facilities. The review shows that health management positively impacts accessibility, service quality, effectiveness, and evidence-based policymaking. Effective strategies include strategic planning, internal managemen human resource management, technology use, and community involvement, although challenges like limited human resources and Electronic Medical Record implementation remain

Masalah kesehatan internasional adalah hipertensi, penyebab utama gagal ginjal, stroke, dan penyakit jantung. Diperkirakan 34,1% orang di Indonesia menderita hipertensi, dan sebagian besar dari mereka tidak mendapatkan pengobatan. Meskipun Puskesmas Welahan 1 menangani hipertensi, pasien sering mengalami kesulitan mengontrol tekanan darah mereka karena berbagai macam obat yang tersedia. Tujuan dari penelitian ini adalah untuk mengetahui seberapa efektif terapi monoterapi dan kombinasi untuk mencapai target tekanan darah pasien hipertensi di Puskesmas Welahan 1 dan bagaimana berbagai obat mempengaruhi kontrol tekanan darah. Data dari 60 pasien hipertensi yang memenuhi kriteria inklusi dianalisis selama tiga bulan menggunakan pendekatan cross-sectional. Digunakan statistik inferensial dan deskriptif, seperti uji chi-square. Tidak ada korelasi signifikan antara kontrol tekanan darah sistolik dan diastolik dan jenis terapi obat (p > 0,05). Namun, pasien yang menerima amlodipine atau amlodipine + captopril lebih mampu mengontrol tekanan darah mereka, dengan rasio kemungkinan 0,857 untuk tekanan sistolik dan 6,429 untuk tekanan diastolik, masing-masing.  Hasilnya menunjukkan bahwa terapi kombinasi mungkin membantu mengontrol tekanan darah diastolik, meskipun jenis obat tidak mempengaruhi tekanan darah secara langsung

Pharmaceutical services are carried out to achieve definite results in improving the quality of life of patients in the form of direct and resposibels services related to pharmaceutical preparations. In implementing pharmaceutical services, health centers already have a standard that is used as a guideline in its implementation. The consequences of implementing pharmaceutical services that do not comply with standards are medication errors and inappropriate use of drugs, there are expired drugs and overlapping budgets. The purpose of this study was to analyze the implementation of pharmaceutical service standards in health centers, BMHP and clinical pharmacy services based on PMK No. 74 of 2016 at the Paduraksa Health Center, Pemalang District. This study is a non-experimental study with a descriptive design that will provide an analytical description of the implementation of pharmaceutical service standards at the Paduraksa Health Center, Pemalang District based on the guidelines in the Minister of Health Regulation Number 74 of 2016. The population and sample in this study were all pharmaceutical personnel who were responsible for managing pharmaceutical service standards at the Paduraksa Health Center, by conducting interviews in the form of questions and answers by giving questions verbally to pharmacists or pharmaceutical personnel at the Paduraksa Health Center, Pemalang Regency. The data in the variable analysis looked at the percentage of compliance with standards based on the Minister of Health Regulation No. 74 of 2016.  

The Electronic Medical Record Information System (RME) is an information technology solution used to manage patient medical record data digitally, replacing manual recording systems that are prone to errors and data loss. This report discusses the design and implementation of the Electronic Medical Record Information System (RME) at the Community Health Center, which aims to increase efficiency, accuracy and security in managing patient medical records. This system includes recording medical data, treatment history, diagnosis, drug prescriptions, as well as integration with other health service systems. With RME, the medical service process at the Community Health Center is expected to be faster, more transparent and organized. This research uses a web-based system development method with database-based programming, which allows medical record data to be managed centrally and easily accessed by authorized medical personnel. The results of implementing this system show a significant increase in speed of service as well as a reduction in administrative and medical errors.