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Storage is an activity of storing and maintaining by placing the received pharmaceutical supplies in a place that is considered safe from theft and physical disturbance that can damage the quality of the drug. The purpose of this study was to determine the drug storage system at the Dearh Lanto Dg Pasewang General Hospital Pharmacy Warehouse which includes spatial arrangements, storage methods, stock card recording and drug quality observation. This is done by direct observation The research conducted is descriptive in nature, the data collection method in this study is by direct observation. The data management and analysis techniques that the authors used in this study included reducing the checklists that had been obtained. Based on the results of research conducted at the Pharmacy Warehouse of the Lanto Dg Pasewang Hospital, in general, the drug storage system was 93.22% in the good category. The assessment includes the physical condition of the warehouse with a value of 90.47% in the good category. How to store drugs with a value of 93.33%. Stock card recording with a percentage value of 100% is in the good category. Drug quality monitoring with a percentage value of 100% is in the good category, so that the medicines stored in the Warehouse of the Regional General Hospital Lanto Dg Pasewang Jeneponto are in good condition and the quality of the drugs is maintained.

Anxiety is one of the complaints of patients with Chronic Kidney Failure (CKD) undergoing hemodialysis. CAM (Complementary Alternative Medicine) therapy as a substitute for drugs using lavender aromatherapy is expected to reduce anxiety levels in CKD patients who are undergoing hemodialysis therapy. The aim of the study was to determine the effect of inhaled aromatherapy on reducing anxiety levels in CKD patients undergoing hemodialysis at Grandmed Lubuk Pakam Hospital. This type of research is quantitative research with a pre-experimental research design with one group pre-test and post-test approaches. The sampling technique in this study was total sampling with a total of 20 respondents. Data analysis was carried out using the sample paired t-test. The results of the study obtained a p-value of 0.00 where the p-value was <0.05, it can be concluded that there was a significant effect after being given inhaled aromatherapy to decrease anxiety values in CKD patients at Grandmed Lubuk Pakam Hospital. The conclusion in this study is that lavender inhalation aromatherapy has a significant effect on reducing anxiety levels in CKD patients undergoing hemodialysis and it is recommended for health workers to further improve anxiety management with non-pharmacological measures.

Drug-resistant tuberculosis (TB) is an escalating global health issue, particularly with the rise of multidrug-resistant (MDR-TB) and extensively drug-resistant TB (XDR-TB), which complicate treatment and control efforts. Resistance to both first-line and second-line drugs weakens the effectiveness of standard WHO-recommended therapies, while alternative drugs can cause severe side effects and reduce patient adherence. This study aims to explore the integration of bioinformatics and pharmacogenomics in supporting personalized TB treatment to improve therapeutic success and reduce the risk of further resistance. The research employed a laboratory-based experimental design with a bioinformatics approach, involving TB patients with clinical evidence of drug resistance. Clinical samples were analyzed through whole genome sequencing to identify gene mutations associated with resistance, followed by pharmacogenomic mapping to predict pharmacological responses based on patients’ genetic variations. The results revealed several specific gene mutations consistently linked to resistance and produced individualized therapeutic recommendations that were more targeted than standard protocols. Effectiveness evaluation demonstrated that genome-based personalized therapy yielded higher treatment success rates, faster recovery times, and lower rates of subsequent resistance. These findings highlight the significant potential of precision medicine in TB management, particularly for resistant cases that are difficult to treat with conventional approaches. In conclusion, the integration of bioinformatics and pharmacogenomics plays an essential role in strengthening TB treatment strategies through a personalized, adaptive, effective, and sustainable approach. Nevertheless, its implementation still faces challenges such as high costs, limited infrastructure, and the need for clear regulations regarding the use of patients’ genomic data.

Drug management is a cycle including selection, procurement, distribution and use which is supported by an appropriate organizational structure, finances and management information system. The aim of this research is to determine drug management in the Pharmacy Installation at RSUD dr. Soeratno Gemolong, Sragen Regency.This research uses prospective and retrospective methods. Where retrospective data is taken from 2022 data. Prospective data is taken through direct observation. The results of this research are: the percentage of available funds and the required funds is 80%, the percentage of procurement and actual use is 98%, invoice errors are 0.47%, there are no delayed payments by hospitals, compatibility between drugs and stock cards is 100% , drug availability level of 16 months, warehouse management system with FIFO, FEFO and LASA marking systems, average time used to serve compounded prescriptions is 11 minutes and non-mixed prescriptions is 7 minutes, conformity of drug items with the National Formulary is 93%, frequency of procurement of each drug item 4-6x a year, turn over ratio 3 times, percentage of expired and damaged drug value 5.05%, dead stock percentage 3%, number of drug items per prescription sheet 3.5 items, percentage of prescriptions with generic names 88%. These results indicate that drug management in the Pharmacy Installation at RSUD dr. Soeratno Gemolong, Sragen Regency is not yet good.

Background: The results of an interview with Dr. Gunawan Leonard, the incidence of OA Genu is often complained of by female patients at the Primary Metro Pundu clinic. This is due to long working hours and hard work. Management from the clinic still uses pain relievers such as ibuprofen. Long-term use of this drug will cause side effects on the body. To minimize these side effects, the researchers carried out non-pharmacological treatment with acupressure at the ST 36, ST 35, EX-LE 2, EX-LE 4, and BL 40 points in reducing OA pain. Objective: To determine the difference before and after being given acupressure in reducing OA pain in perimenopausal women. Method: This type of research is quantitative. The population of this study were all women of perimenopausal age who had osteoarthritis genu at the Metro Pundu Primary Clinic, Central Kalimantan, as many as 32 people. The number of samples used Freder's formula was 20 samples, and data processing used Shapiro Wilk for the normality test to obtain normally distributed data results and paired sample t test with the results of ha accepted. Results: There was a decrease in OA pain scale in perimenopausal women before and after being given acupressure treatment, This shows the effect of acupressure in reducing genu osteoarthritis pain in perimenopausal women.

According to available data, colorectal cancer (CRC) is one of the most common malignant neoplasms. Depending on location, type of cancer, or gender, this disease ranks 2nd to 4th in terms of worldwide incidence. CRC from year to year shows an increasing trend both in terms of morbidity and mortality. Many factors may be responsible for the development of this disease, including genetic and environmental factors. Although CRC-related mortality is very high in high-income countries, CRC-related incidence and mortality is also increasing in developing countries. CRC that is detected early is completely curable with surgery and subsequent treatment. However, the recurrence rate is high, and cancer drug resistance increases the treatment failure rate. Access to early diagnosis and treatment of CRC for survival is somewhat possible in developed countries. However, these facilities are rarely available in developing countries.

Outpatient services are an important part of health services provided by hospitals. However, some BPJS hospitals experience obstacles in providing efficient and quality outpatient services, such as long queues, long waiting times, and lack of a good management system. the application of Lean Management to the outpatient services of BPJS patients in hospitals can help hospitals improve operational performance, so as to increase public trust in BPJS Health. This study aims to analyze the application of Lean Management to the outpatient services of BPJS patients in hospitals. This research uses a literature study method or Systematic Literature Review using the Google Scholar search engine and journal databases, such as Researchgate. The results showed that most outpatient service activities for BPJS patients still have patient waiting times below the established service standards. In analyzing the flow that patients go through, each activity is identified into two groups, namely Value Added (VA) as an activity that is considered necessary and profitable and Non Value Added (NVA) as an activity that is considered unnecessary. Based on the percentage of waste in the form of the largest waiting time can be described, namely, 35.1% in the registration process, 30.2% in the poly examination process, and 20.7% in the process of receiving drugs in the pharmaceutical installation

The main problem in this research is the management of drugs in the Pharmacy Installation of RSUD Prof. Dr. H. M. Anwar Makkatutu which has not been handled properly. There are various types of pharmaceutical logistics, namely drugs and consumables, many types of incoming drugs and medical equipment, with different delivery times and drug expiration dates, the pharmacy must manage it well, starting from the process of distributing and storing drugs and consumables. from warehouse to depot. The pharmaceutical system that is still manual causes repeated double checks, the data collection of expired drugs is not correct, there is no application that makes it easy for pharmacy officers to check what drugs are about to expire and are about to expire so that it requires a long time and excessive energy. With the above problems, the development of drug management applications through the fifo and fefo methods in SIMRS when receiving, storing and releasing drugs and medical equipment is needed for smooth service in pharmaceutical installations so that officers can work effectively, efficiently, and improve service quality. as well as the economic disadvantages of hospital management can be minimized and produce reports that are faster and more accurate in the management and planning of drug supplies. Pharmacy officers can take advantage of drug management through the fifo and fefo applications based on batch numbers and expiration dates to complete all the shortcomings and weaknesses of the existing SIMRS application in order to maximize services at the Pharmacy Installation. This research is a quasi experimental research to determine the difference in the duration of the use of time and energy before and after using the application. The research was carried out at the pharmacy installation of Prof. Dr. H. M. Hospital. Anwar Makkatutu Bantaeng from August to October 2020.

Storage is an activity of storing and maintaining by placing drugs received in a place that is considered safe from theft and physical disturbances that can damage the quality of drugs. Pharmaceutical Wholesalers are companies in the form of legal entities that have permits for the procurement, storage, distribution of drugs or materials in large quantities in accordance with statutory provisions (Permenkes, 2011). Using primary data sources and secondary data. This study aims to determine the implementation of storage circulation in drug warehouses in pharmaceutical distribution companies at PT. Bharadah Sakti Semarang. The data collection method was carried out through interviews, observation, and documentation at the PT. Bharadah Sakti Semarang. The observation results obtained indicate that the management of drug supplies in warehouses uses the Economic Order Quantity (EOQ) method.  

Pharmaceutical preparations is a term that covers all forms of pharmaceutical preparations ranging from drugs, medicinal ingredients, traditional medicines to cosmetics. This term has been regulated in Government Regulation of the Republic of Indonesia Number 51 of 2009 concerning Pharmaceutical Work. Management of pharmaceutical preparations is a cycle of activities starting from the selection, scheduling needs, receiving, storage, distribution, destruction and withdrawal, control, which is necessary for pharmaceutical service activities. The method used in this study is a Systematic Literature Review (SLR) of ten national journals which were obtained using online database facilities via the Google Scholar, Refseek, and Sciencegate pages. Journals were selected based on publications published between 2018 and 2023. There were obstacles in the implementation of pharmaceutical preparations, including planning that was still conservative, from delays in drug procurement in demand and distribution, resulting in empty drug supplies. However, not all aspects are problematic. There are many other aspects of the mechanism of pharmaceutical preparation that are carefully programmed and procedurally appropriate. This matter needs to be done routinely and continuously, and with written commitments for pharmaceutical preparations in Indonesia in supporting SKN it can be categorized as quite good.