Publication Search

<p style="text-align: justify;"><em>As the smallest unit of government in promoting local economic growth, the village plays a crucial role; therefore, the government encourages sustainable village development based on local advantages, community participation, and economic empowerment—one of which is the Desa Berdaya Program implemented in Mojokerto Regency. The Desa Berdaya Program promotes village self-reliance by developing human potential and strengthening the local economy. The program’s success depends on the synergy between government policies, individual/team performance, and active community involvement to achieve the goal of independent and sustainable village development. This study aims to evaluate the implementation of the Desa Berdaya Program in Mojokerto Regency by examining the alignment between the planned initiatives and actual conditions in the field, as well as identifying the challenges that influence the program’s effectiveness. This study utilizes a qualitative descriptive approach, gathering data through observations, interviews, and document analysis. The data were processed through stages of collection, reduction, organization, and interpretation to draw conclusions. The results of the study indicate that the performance of the Desa Berdaya Program in Mojokerto Regency can be considered successful, yet improvements are needed for 2025–2026. The program’s success is influenced by performance management factors (Armstrong), including individual, leadership, team, system, and situational/contextual elements. The inhibiting factor lies in the limited capacity and understanding of individuals regarding the Desa Berdaya Program. Meanwhile, the supporting factors include bureaucratic leadership and effective team performance, attributed to good communication among members.</em></p>

Background: Atherosclerosis is a chronic inflammatory cardiovascular disorder strongly associated with elevated low-density lipoprotein cholesterol (LDL-C) levels and serves as a major predictor of adverse cardiovascular events. This study aimed to investigate the relationship between inflammatory markers (adiponectin and TNF-α) and key biochemical parameters in atherosclerosis patients. Methods:  A case-control study was conducted on 60 participants (aged 40–65 years) recruited from private cardiac clinics in Fallujah, Iraq, between October and December 2024. Subjects were stratified into two groups: 30 atherosclerosis patients (diagnosed by specialists) and 30 age-matched healthy controls. Blood samples were collected, centrifuged, and analyzed for CRP, TNF-α, adiponectin, PAI-1, MDA, GSH, sodium (Na), and magnesium (Mg) levels using standardized biochemical assays. Statistical analysis was performed using SPSS, with significance set at *p* ≤ 0.001. Results: Atherosclerosis patients exhibited significantly elevated serum levels of CRP (2.21 ± 14.46 vs. 1.07 ± 7.76 mg/dL), TNF-α (15.14 ± 120.86 vs. 4.27 ± 65.16 pg/mL), PAI-1 (6.52 ± 0.82 vs. 2.02 ± 0.42 ng/dL), MDA (590.26 ± 29.64 vs. 155.52 ± 25.19 ng/mL), and Na (140.16 ± 1.18 vs. 125.46 ± 6.17 nmol/L) compared to controls (*p* ≤ 0.001). Conversely, adiponectin (0.18 ± 1.81 vs. 0.67 ± 4.18 mg/dL), GSH (22.79 ± 1.37 vs. 40.81 ± 3.05 μg/mL), and Mg (1.46 ± 0.175 vs. 1.84 ± 0.67 nmol/L) were markedly reduced in patients. ROC curve analysis demonstrated perfect diagnostic accuracy (AUC = 1.0) for CRP, TNF-α, and adiponectin in distinguishing patients from controls. Conclusion: The study highlights pronounced dysregulation of inflammatory, oxidative, and metabolic pathways in atherosclerosis, with CRP, TNF-α, and adiponectin serving as robust discriminative biomarkers. These findings underscore the potential of targeting these pathways for therapeutic intervention and early diagnosis.

Background: Human immunodeficiency virus (HIV) remains a critical global health issue, with 88.4 million infections and 42.3 million AIDS-related deaths to date. In 2024 alone, 39.9 million individuals are living with HIV, 630,000 deaths occurred, and 1.3 million new infections were recorded. Tenofovir Disoproxil Fumarate/Lamivudine/Dolutegravir (TLD) is a widely used antiretroviral therapy, but its reproductive and oxidative effects remain underexplored in female models, particularly in the South-South region of Nigeria.Objective: This study aimed to evaluate the reproductive toxicity and oxidative stress effects of TLD on the ovaries and uterus of adult female Wistar rats.Methods: Ten adult female Wistar rats (156–187g) were divided into control and treatment groups (n=5). The control group received standard diet and distilled water, while the treated group received daily doses of TLD (Tenofovir 5 mg, Lamivudine 5 mg, and Dolutegravir 0.8 mg/kg body weight) for 90 days. At the end of the treatment, animals in estrus phase were sacrificed for biochemical, histological, and hormonal analysis.Results: The treated group showed a significant reduction in body weight but no significant changes in ovarian or uterine weight. Oxidative stress analysis revealed decreased MDA and increased SOD, GPx, and CAT in the uterus. Hormonal levels were not significantly different. Histologically, the treated group displayed impaired follicular development, atretic follicles, cysts, enlarged endometrial cavities, and thicker endometria.Conclusion: TLD administration induced notable reproductive alterations in female Wistar rats, highlighting potential implications for its use in women of reproductive age.

Technicians in radiology departments are continuously exposed to ionizing radiation, which can affect biological systems. This study aimed to investigate the effects of low-level ionizing radiation (IR) on antioxidant enzymes and blood components in radiology personnel. The study involved forty participants aged 30 to 45 years, divided into three groups: G1 as the control group (n=10), G2 consisting of 15 radiologists, and G3 comprising 15 radiology technology workers. Participants in G2 and G3 had work experience ranging from 5 to 15 years and were employed in X-ray and CT scan departments at General K1 Hospital, Kirkuk. The measured parameters included white blood cells (WBCs), platelets, and lymphocytes, as well as malondialdehyde (MDA), superoxide dismutase (SOD), total antioxidant capacity (TAC), and albumin as indicators of redox status. The results showed a significant increase in MDA levels among radiology workers compared to the control group, while SOD, TAC, and albumin levels decreased (P<0.05). Additionally, radiation-exposed workers had a higher mean count of WBCs and lymphocytes than the control group (P<0.05), whereas platelet levels were significantly lower (P<0.05). This study indicates that occupational radiation exposure can cause short-term changes in blood cells and increase the circulating redox state in healthcare workers operating in CT and IR environments compared to those not exposed to radiation. These findings highlight the importance of regular health monitoring for radiology personnel to mitigate potential long-term effects of radiation exposure.

Tooth extraction often triggers anxiety in patients due to the use of invasive medical instruments. Anxiety management can be addressed pharmacologically or non-pharmacologically. Aromatherapy using red ginger essential oil (Gingiber Officinale var. Rubrum) is a non-pharmacological method that has the potential to reduce anxiety effectively. This study aims to determine the effectiveness of red ginger essential oil in reducing the anxiety levels of patients undergoing tooth extraction. This quasi-experimental study employed a pretest-posttest design on 96 tooth extraction patients at RSKDGM Makassar. Anxiety levels were measured using the Modified Dental Anxiety Scale (MDAS) questionnaire before and after inhaling red ginger essential oil aromatherapy for 10 minutes. Data were analyzed using the Wilcoxon test with SPSS 26. The results showed a significant decrease in patients' anxiety levels after inhalation of red ginger essential oil aromatherapy. Before the intervention, the majority of patients had moderate anxiety (58.3%), while after the intervention, mild anxiety increased to 59.4% (p-value = 0.000). Red ginger essential oil (Gingiber Officinale var. Rubrum) is effective in reducing patients' anxiety during tooth extraction procedures.

This search intended to speculate the role of lavender ethanolic extract by reducing the toxicity of manganese in male rats. 32 white male Norwegian rats were divided into 4 equal groups. Group 1: as a control group left without treatments (only 1 ml of distilled water/ animal/ day). Group 2: were dosed manganese chloride at a concentration of 100 mg/ kg b.w. / day. Animals in Group 3 and Group 4 were dosed Manganese chloride at a concentration of 100 mg/kg b.w. then lavender ethanolic extract at a concentration of 200 and 400 mg/kg respectively, all by oral gavages and treated daily for six weeks. Then the next criteria were investigated: Neurotransmitters (dopamine and Ach (acetylcholine) in the mid brain) serotonin in serum. Oxidation indicators (glutathione and malondialdehyde in the brain and superoxide dismutase and catalase in serum). The results exhibited in both groups 3 and 4 there were a significant decrease in the concentrations of Ach accompanied by a significant increase in levels of dopamine and serotonin, also return levels of MDA (Malondialdehyde) to normal, as well as a significant increase in GSH (Glutathione) concentrations in rats mid brain. Moreover, the significant rising of SOD (Superoxide dismutase) and CAT (Catalase) levels in serum of rats in these groups indicated a noticeable improvement was achieved by lavender ethanolic extraction as compared to group 2. Conclusion, the antioxidant and antitoxic activity of lavender ethanolic extract promises in grate achievement in various health fields, including medicine, food industries and cosmetics.

Tooth extraction is a minor surgical procedure involving hard and soft tissues in the oral cavity. The level of anxiety towards dental treatment procedures ranks fifth among several other common symptoms that can cause anxiety. Treatment to reduce the level of patient anxiety can be done with pharmacological and non-pharmacological approaches. Jasmine flower essential oil (Jasminun grandiflorum) is one of the non-pharmacological methods used to reduce the level of anxiety in tooth extraction patients. To determine the effectiveness of using jasmine flower essential oil (Jasminum grandiflorum) on the level of anxiety in tooth extraction patients. This study was conducted at the Regional Special Hospital for Teeth and Mouth (RSKDGM) in Makassar. This study is a quasi-experimental study with a pretest-posttest approach. The measuring instrument used was the Modified Dental Anxiety Scale (MDAS) questionnaire which was given before and after giving jasmine flower essential oil for 10 minutes to reduce the level of anxiety in tooth extraction patients. Based on the results of the Wilcoxon test, it showed a significant decrease in the level of anxiety in patients after inhalation of jasmine flower essential oil aromatherapy. Before treatment, the majority of patients had moderate anxiety (47.9%), while after treatment, mild anxiety increased to 89.6% (p-value 0.000). Jasmine Flower (Jasminun Grandiflorum) essential oil is effective in reducing the level of anxiety in tooth extraction patients.

The predictive role of oxidative stress in the pathophysiology of human pregnancy is of particular interest, as oxidative stress is increased in normotensive pregnant women through systemic inflammatory response, reactive oxygen species (ROS), and reactive nitrogen species (RNS). This study involved 40 consenting pregnant women recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. Data obtained were analyzed using GraphPad Prism 9. Results were expressed as mean ± SEM, with a P-value of ≤ 0.05 considered statistically significant. Malondialdehyde (MDA) increased from 3.75 ± 0.42 U/L in normotensive women to 4.53 ± 0.59 U/L in preeclamptic women. However, this increase was not statistically significant (p<0.05; 0.2903). Catalase activity decreased from 114 ± 8.07 U/L in normotensive women to 84.02 ± 21.58 U/L in preeclamptic women, but this decrease was also not statistically significant (p<0.05; 0.1909). Superoxide dismutase (SOD) increased from 40.82 ± 1.23 U/L in normotensive women to 71.90 ± 5.61 U/L in preeclamptic women. This increase was statistically significant (p<0.05; <0.0001). Glutathione peroxidase (GSH) decreased from 66.74 ± 10.35 U/L in normotensive women to 50.63 ± 8.96 U/L in preeclamptic women, but this decrease was not statistically significant (p<0.05; 0.2466). These findings suggest the potential predictive roles of these biomarkers in identifying and monitoring preeclampsia.

The training for MDA/TPA teachers in Guguak Tabek Sarojo Village, Agam Regency, aims to improve teachers' ability to manage classes effectively and efficiently. This ability is very important in creating a good learning process, especially in non-formal educational institutions, namely MDA/TPA, which often experience problems with facilities, learning methods and time management. The method used in this training activity was carried out through the delivery of material on class management, discussions, questions and answers and teaching practice simulations. The results showed that after participating in the training, teachers had a better understanding of class management strategies, the use of interesting learning methods and the positive impact was seen from the increase in teacher participation during the training process.

This article discusses the potential role of mosques as centers for educational innovation and training to improve community capacity. Through a literature review and case study, this article aims to explore how mosques can transform from simple places of worship into comprehensive learning centers. The method used in this study is a qualitative method, by making books, magazines, articles and journals related to the research theme, focusing on innovative education and training models that can be applied in mosques, the challenges that may be faced, and their potential benefits for the community. The results of the analysis show that with the right approach, mosques can become important buildings in human resource development and community empowerment in two innovations, namely Educational Innovation; (1) Establishing non-formal educational institutions such as TPA and MDA, (2) Routine syllabus studies, (3) Arabic language course institutions. Training Innovation; (1) funeral prayer training, (2) Youth mosque leadership training, (3) Preaching training.

Background: Petai seed extract (Parkia speciosa Hassk.) contains flavonoids and polyphenols. These compounds have good antioxidant activity to lower oxidative stress. The product of oxidative stress is called MDA (Malondialdehyde) which can be used as an indicator of oxidative stress. The study aimed to determine the effect of petai seeds on MDA serum levels in rats (Rattus novergicus) on a high-fat diet. Objective: To determine the effect of the administration of        Methods: This research was a true experimental study with post test only control group design. A total of 25 rats were divided into five groups : negative control (K-), positive control (K+), treatment 1 (P1), treatment 2 (P2), and treatment 3 (P3). The K+, P1, P2, and P3 groups were given a high-fat diet for 30 days and continued to administer extract of petai seeds doses of 100 mg/kgBW, 200 mg/kgBW, and 400 mg/kgBW consecutively for P1, P2, P3 for 10 days. The levels of MDA serum were measured by the P. P. Nair method. Data were analyzed using the nonparametric Kruskal-Wallis test and Post-Hoc Mann-Whitney test.Results: The results of this study indicate the effect of the administration of petai seeds (Parkia speciosa Hassk.) on the MDA serum levels. Conclusion: The study concludes that extract of petai seeds with 100 mg/kgBW has no effect on MDA serum levels, while in rats with a dose of 200 mg/kgBW and 400 mg/kgBW can decrease MDA serum levels.

This document is a project proposal plan for the creation or development of applications by PT. Multi Development Application (MDA) through the MDA Content Archive Platform (CAP) solution which accommodates and optimizes paper-based, digital data storage (Application Optimized Storage) for the benefit of banking organizations, the private sector, government, educational institutions and all kinds of business entities, which have The desire to realize a real form of cooperation in efforts to protect data or archives that have high historical value, so that the data or archives are safe and not easily damaged.

The purpose of this study was to determine how the Al-Barqy method affects the ability to read the Al-Qur’an at MDA Nurul Ihsan Mudiak Lolo Barat Sungai Pagu District South Solok Regency. This research uses pre-experimental methodology and is quantitative in nature. The number of grade I-IV MDA students who became the population of this study were 42 students. Collecting odd semester grades, then doing a normality test, the researcher determines a random sample as a sampling technique. Tests were used to collect data. Analysis of data using descriptive analysis and t-test. The results of the study based on the results of the Paired Sample T-test test obtained a t score of 9.376> t table which is 1306, and the probability value of sig.  (2-tailed) 0.000 <0.05 so that it can be inferred that Ha is accepted and Ho is rejected which shows that there is a significant effect of the Al-Barqy method on the ability to read the Qur’an to students at MDA Nurul Ihsan Mudiak Lolo Barat, Sungai Pagu District, South Solok Regency.

This study aimed to investigate the physiological impact of academic stress, particularly examination stress, on biochemical indices among college students at the University of Tikrit. A total of 60 healthy students (30 in an experimental group and 30 in a control group) aged 19-21 years participated in this cross-sectional study. Salivary samples were collected during pre-examination and post-examination periods to measure levels of cortisol, malondialdehyde (MDA), glucose, and total antioxidant capacity (TAC). The results indicated significant increases in cortisol, MDA, and glucose levels in the pre-examination period compared to the post-examination period, suggesting heightened stress responses. Conversely, TAC levels were significantly higher in the post-examination period, indicating a potential recovery or response to oxidative stress. The findings support the hypothesis that academic examinations can induce significant physiological stress in students, reflected by changes in salivary biochemical markers. These stress responses may influence overall student health and academic performance, suggesting the need for strategies to manage stress among students during examinations.

This study aims to determine the effect between the variables Brand Image (X) and Price (X2) on Consumer Purchase Interest (Y) at MDA Collection. This type of research is quantitative research which is used to test the relationship of a variable to other variables which emphasizes its analysis on numbers processed by statistical methods. The data collection techniques used are primary data and secondary data. Sample selection using saturated sampling method, the number of samples in the study obtained 40 respondents at MDA Collection. Data analysis using the Statistical Program for Social Science (SPSS). The analysis techniques used are validity and reliability tests, classical assumption tests, multiple linear analysis tests and hypothesis testing. Based on the results of this study, it shows that partially the Brand Image variable (X1) has a significant effect on Consumer Purchase Interest (Y). Partially Price (X2) has a significant effect on Consumer Purchase Interest (Y). Simultaneously Brand Image (X1) and Price (X2) affect Consumer Purchase Interest (Y).

STAIN MADINA KKN Group 26 was held in Balimbing Julu Village, Padang Bolak Julu, North Padang Lawas, North Sumatra. The main problem is that in Balimbing Julu Village there are no recitation groups specifically for children or teenagers. In Balimbing Julu Village there is no Madrasah Diniyah Awaliyah (MDA) so children's knowledge about religion is still minimal. In fact, there are still many elementary school children who don't know the hijaiyah letters or short letters. With this recitation, children are more enthusiastic about memorizing short suras, practicing prayer and learning monotheism of the Al-Qur'an.By establishing a study park, children can play while learning religious knowledge. Therefore, as STAIN MADINA KKN students, we collected data by conducting observations and surveys (interviews) with the Balimbing Julu community to hold a recitation garden for children, Friday afternoon recitation for mothers and youth recitation or Naposo Nauli Bulung (NNB) specifically for Friday evenings. 'at the existence of these recitations can strengthen ties between communities.To overcome this problem, we planned to alternately set up a place for recitation at the homes of members of the study group, specifically for children's study gardens, we deliberately held it at the KKN post and the next recitation location was taken over by the chairman of the NNB, namely Maralohot Siregar. With this recitation, it is hoped that it will broaden the knowledge of children, recitation mothers and Naposo Nauli Bulung (NNB). After we established a recitation garden, Friday afternoon recitation for women, and Friday evening recitation for Naposo Nauli Bulung (NNB), we understood that the support of the Balimbing Julu village community had a very important role in realizing these recitation activities. People can learn about the meaning of togetherness, solidarity and kinship.

Real work education (KKN) is a service to the community carried out by students through the guidance of lecturers. This service aims to establish synergy between universities and the community, especially for students to apply the knowledge gained from higher education. In welcoming the month of Muharram, the people of Aek Godang have never celebrated 1 Muharram and also the MDA School in Aek Godang Village experienced obstacles because one of the facilities was that students did not meet the capacity they should have to carry out learning at the MDA. This research aims to practice 1 Muharram and also preserve MDA which is no longer operating. The results of this research reveal that: 1. The practice of Muharram 1 in Aek Godang village, Hulu Sihapas sub-district, North Padang Lawas Regency, namely the implementation of recitations by inviting teachers to deliver tausiyah regarding the Islamic New Year.2. Conservation of MDA Al ABROR Aek Godang Village, Hulu Sihapas District, North Padang Lawas Regency, namely socializing to children that studying religion is just as important as gaining general knowledge and also telling children that studying religion is an important thing because it is guides and also guidelines for the life of Muslims.

Oxidative stress is a condition where there is an imbalance between oxidants and antioxidants in the body which can trigger psychological stress. Oxidative stress can be reduced by consuming exogenous antioxidants (antioxidants from outside), where green tea is thought to be able to reduce oxidative stress. The aim of this study was to examine the effect of steeping green tea on blood glucose and Malondialdehyde (MDA) levels in male Wistar Strain white rats exposed to psychological stress. The design used in this research was Randomized Post Test Only Group Design. There were 5 groups of mice; 2 are a normal control group and a stress control group, and 3 treatment groups. Previously, the mice were given psychological stress 1 x 24 hours in the form of disturbed sleep patterns, so that the experimental animals experienced oxidative stress, then green tea was given to the treatment group with a single dose of 3.6 ml/head in the 1st hour in the group. treatment 1, 6th hour in treatment group 2, and 24th hour in treatment group 3. Statistical analysis used the Manova test.  Based on statistical analysis, it shows that there was a decrease in blood glucose and Malondialdehyde (MDA) levels in all treatment groups given exposure to psychological stress and steeping green tea.  A single dose of green tea brewing in experimental animals experiencing oxidative stress was proven to be able to neutralize oxidative stress in the 1st hour after administration of green tea brewing and the antioxidant activity still lasted up to 24 hours.

This research is motivated by phenomena or symptoms from the author's observations about teacher creativity in developing students' self-confidence in learning the Koran at Madrasah Diniyah Awaliyah (MDA) Nurul IKhlas Jorong V Meeting, that many students in learning the Koran are not confident and even when reading the Koran many students are nervous and even many make mistakes in reading the Koran, this happens because students' confidence in learning the Koran is still minimal. This research is a field research (field research) which is descriptive qualitative. The data collection used during this research was by using data collection techniques through interviews and observation. This study uses key informants and supporting informants. The key informant in this study was 1 person, namely the teacher learning the Koran while for the supporting informants, namely class IV MDA Al Ikhlas, then the authors conducted a descriptive analysis with data reduction and to test the validity of the data in this study the authors used data triangulation. Based on the results of the study it can be understood that the Al-Quran teacher at MDA Al Ikhlas is already creative when teaching in class so that the self-confidence of the students increases.

One of the main activities of hospital nutrition services is the provision of meals for patients in the hospital. The goal is to provide quality food in accordance with the nutritional needs, cost, safety and acceptance of the patient to achieve optimal nutritional status The food management information system currently used in the Nutrition Installation of Rsud Prof. DR H M Anwar Makkatutu Bantaeng is still using a manual (conventional) system, starting from calculating the need for foodstuffs to ordering foodstuffs. This is due to the unavailability of applications that can more efficiently save energy and time. So far, calculating food needs requires a long time and energy is needed by more than one person. The type of research method used in this research is a quantitative quasi-experimental research method which aims to show a causal relationship and to investigate the relationship and clarify the causes of events, where in this study it focuses on the use of energy and the duration of time used before and after using the application. computers for food management activities in the Nutrition Installation, in this case the calculation of food needs. Based on the results of the research, before and after using a computer-based management information system application to improve the efficiency of food administration at the Rsud nutrition installation, Prof. DR. HM Anwar Makkatutu Bantaeng (SPMIG), there was a difference in time duration, where the time used in calculating the need for foodstuffs was shorter or shorter. Food administration at the Nutrition Installation of Prof. DR H Makkatutu Bantaeng Hospital before using the SPMIG application software an average of 180 minutes - 210 minutes and after using the SPMIG application software the average was 1 - 10 minutes, so the time difference used was 170 minutes.