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A 63 year old male patient came to the emergency room with complaints of weakness since 5 days of SMRS. Complaints are accompanied by nausea, vomiting, pain throughout the stomach, and liquid bowel movements. The patient also complained of low back pain that spread to both legs and made it difficult to walk. The patient also feels that he is urinating a little and seems to be stuck. Two weeks ago the patient had a fever accompanied by a cough. On physical examination, BP 90/60 mmHg, HR 111 x/minute, RR 20 x/minute, BMI 20.3 kg/m2, suprapubic area tenderness, right CVA tapping pain. Investigations Hb 11.73 g/dl, urea: 73 mg/dl, creatinine: 3.45 mg/dl, tubex: negative, dengue Ig M: negative, dengue Ig G: positive. Abdominal ultrasound examination revealed multiple nephrolithiasis dextra. On chest X-ray examination, there was an increased bronchovascular pattern, an air bronchogram (+) with an impression of bronchitis. The finding of multiple nephrolithiasis dextra indicates that the patient's kidney failure is chronic in nature, however, DHF that is not treated properly causes worsening of kidney function, giving rise to the condition of ACKD.

Aides aegypti or Aides albopictus is a type of mosquito that carries and transmits dengue virus to humans. Dengue hemorrhagic fever appears as an Extraordinary Event (KLB), causing panic in the community because it has the risk of causing death and spreads very quickly. Based on records from the Directorate for Prevention and Control of Infectious Diseases (P2PM) until Week 36, the cumulative number of confirmed cases of DHF from January 2022 was reported as 87,501 cases (IR 31.38/100,000 population) and 816 deaths (CFR 0.93%). Sampang Regency, East Java, is currently starting to anticipate the possibility of an outbreak of dengue fever. After the local regency government released three districts that were considered prone to Dengue Hemorrhagic Fever (DHF), namely Sampang District, Omben District and Torjun District. The Health and Family Planning Service (Dinkes-KB) of Sampang Regency, East Java, noted that cases of dengue hemorrhagic fever (DHF) in the area have decreased in 2021 compared to the number of cases that occurred in previous years. This study aims to determine the implementation of dengue hemorrhagic fever (DHF) prevention policies in Sampang District and what are the inhibiting factors. In this study, researchers used a qualitative descriptive method that used data collection such as interviews, observation and documentation studies. Based on the research results in assessing the Implementation of Dengue Hemorrhagic Fever (DHF) Management Policies in Sampang Regency, it has not been maximized when viewed from several indicators of evaluating the implementation of public policies, namely (1) Policy resources such as a lack of health workers, sufficient health facilities and funds, (2) ) the disposition or attitude of the executors is not firm and the lack of community participation in PSN activities, (3) economic, social and political conditions that are not conducive.

Dengue Hemorrhagic fever (DHF) is caused by a dengue virus that spreads through the bite of the Aedes aegypti mosquito, which breeds a lot in densely populated areas with humid and warm climates. Anti-mosquito drugs in the form of burns, sprays, lotions, or other types are already widely used, but these anti-mosquito drugs are not entirely beneficial. This research is purely experimental research with Post-test Only Control Group Design by making air spray solution products from noni leaf infusion and cananga flower, which are analyzed descriptively and analytically. Experiments carried out with Randomized Complete Design 1 time repetition to analyze effectiveness. The study used two factors: treatment (P) using infusion products while the control (K) using distilled water. From the results of mixing, it was obtained as much as 400 ml of infusion solution. Obtained in each measurement, there was a reduction in live larvae until the last measurement. Noni leaf contains five flavonol glycosides (flavonoid compounds) as respiratory poisons and a combination of saponins and tannins as stomach poisons that have the killing power against the death of Aedes aegypti larvae. Cananga flower extract itself can resist mosquitoes because of the content of linalool, geraniol and eugenol. This makes a change in the larvae's behavior, where the previously active movement will be slow and eventually will die.

Demam Berdarah Dengue atau sering disingkat sebagai DBD yang dalam bahasa medisnya lebih dikenal dengan istilah Dengue Hemorrhagic Fever (DHF) merupakan penyakit menular yang disebabkan oleh virus dengue yang ditularkan melalui gigitan nyamuk aedes aegypti, yang menyebabkan gangguan pada pembuluh darah kapiler. Tujuan penelitian untuk mengetahui gambaran pengetahuan keluarga tentang pencegahan penyakit demam berdarah dengue (DBD) di wilayah kerja Puskesmas Telaga Biru Kabupaten Gorontalo. Desain penelitian menggunakan penelitian kuantitatif dengan rancangan deskriptif analitik. Populasi dalam penelitian ini yaitu sebanyak 79 responden dan sampel pada penelitian ini berjumlah 79 responden. Teknik pengambilan sampel menggunakan total sampling. Hasil penelitian didapatkan tingkat pengetahuan keluarga tentang pencegahan penyakit demam berdarah dengue (DBD) di wilayah kerja Puskesmas Telaga Biru Kabupaten Gorontalo sebanyak 58 responden (73,4%) dengan tingkat pengetahuan kurang dan sebanyak 21 responden (26,6%) dengan tingkat pengetahuan baik. Kesimpulan dalam penelitian ini adalah tingkat pengetahuan keluarga tentang pencegahan penyakit demam berdarah dengue (DBD) di wilayah kerja Puskesmas Telaga Biru Kabupaten Gorontalo sebanyak 58 responden (73,4%) dengan tingkat pengetahuan kurang.