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Hematoxylin-eosin staining is a crucial technique used in histopathology to differentiate tissue components. One of the steps in this staining is changing the color of the nucleus, which was previously reddish due to the acid solution, to bluish; this step is known as blueing. The bluing agent, lithium carbonate, is commonly used in laboratories but has side effects and low availability. Sodium bicarbonate, also known as baking soda, can be used as an alternative due to its optimal pH, lower toxicity, and availability. This study aims to find out whether baking soda is as effective as lithium carbonate when used as a blueing agent for hematoxylin-eosin staining. The study design used was a true experimental post-test only control group design with a sample size of 32 preparations. Results of preparations using baking soda microscopically had good color uniformity, the nucleus was visible, the cytoplasm was clear, so the boundaries between cells were visible, and no cell lysis was found. In percentage terms, 14 preparations received a score of two (87.5%), two preparations received a score of three (12.5%), followed by a P value of 0.051 after carrying out the Fisher's exact test in bivariate analysis. Based on the results, baking soda is as effective as lithium carbonate, so it can be used as an alternative to bluing agent of hematoxylin-eosin staining.

Background: Hypertensive Disease in Pregnancy (HDK) is a vascular disorder that occurs during pregnancy, arises during pregnancy or in the postpartum periode, and is one of the most common causes of maternal death. Objective: this study was to determine how factors of having a history of hypertension, obesity, and using hormonal birth control impact the incidence of hypertension Disease in pregnancy (HDK). Metodes: the research approach used was analytic observation with a croos sectional design. This study involved 332 pregnant women who come to the Health Center. A sampel random sampling technique, with a sample size of 183 was used. In this study, the independent variables were history of hypertension, obesity, and hormonal birth control use; the incidence of HDK was the dependent variable. Data was collected using a documention study approach with an observation sheets. To analyse the data, a logistic regression statistical test was used with an error rate of α 0.05. The results showed that pregnant women with HDK were exposed to hypertension 45.6%, and hormonal birth control by 36.3%. The result of bivariate analysis of hypertension history with HDK is o.o1 < α 0.05, and the variable of obesity with HDK is 0.024 < α 0.05 and the variable of hormonal birth control history with HDK is 0.21% < α 0.05. The conclusion of the results showed that of the three factors contributing to the incidence of HDK, only the history of hypertension and obesity had a significant influence, with a history of hypertension accounting for 9.9% of HDK cases. Therefore, it is recommended that Strengthing Integrated Antenatal care for increasing the role of mindwives and general practitioners in better screening of pregnant women at risk.

The development of increasingly advanced technology has a major influence on the world of the communications industry and has led to competition between smartphone manufacturers. They compete to produce advantages in products that will be marketed. The number of iPhone users among students has become commonplace, when they buy a product, of course, they do not only see the advantages offered, but they also see the brand they will buy and country of origin, perceived quality and brand image are factors that cannot be underestimated in influencing purchase decisions through customer trust. This research uses quantitative methods with a sample size of 100 respondents. Data sources are primary data and secondary data, primary data obtained from the distribution of questionnaires. This study uses probability sampling with random sampling technique. For the data analysis process using the Smart-PLS version 4.1.0.3 processing tool. Based on the results of research on direct effects, it shows that perceived quality and brand image do not have a significant effect on purchase decisions, while country of origin has a significant effect. The indirect effect shows that customer trust does not mediate the relationship from the influence of country of origin and brand image on purchase decisions, but customer trust is able to mediate the relationship from the influence of perceived quality on purchase decisions.    

Fibroadenoma mammae is a benign breast tumor that occurs due to abnormal proliferation of periductal tissue into the lobules, often found in the upper lateral quadrant area due to the highest distribution of glands in this tissue. FAM is commonly experienced by younger women between the ages of 20-40 years, with a median age of 30 years. The clinical appearance of FAM lumps is typically lobulated, mostly 2-3 cm in diameter, with a firm and mobile consistency, without causing inflammatory reactions, skin dimpling, or nipple retraction. In this case, we report an 18-year-old female patient diagnosed with a breast tumor. The history revealed a lump in the left breast that enlarged within 1 month, initially the size of a marble and growing to the size of a quail egg, occasionally causing pain. On physical examination, the lump was palpable, mobile, without tenderness or signs of malignancy. Ultrasound examination showed signs of a benign tumor.  

Ajwa date (Phoenix dactylifera L.) from Medina, Saudi Arabia, contains a high carbohydrate content. Dates are commonly recognized to be available in two forms: dried fruit that may be consumed directly and concentrated date juice. Concentrated date juice usually gives an unpleasant taste when consumed and requires a large container for storage. This study aims to formulate the effervescent granules using two combinations of acids, namely citric acid and malic acid as a source of acid and sodium bicarbonate as a source of base. The research process was began with macerating dates with 96% ethanol solvent and making a dry extract. Furthermore, effervescent granule preparations were made in three formulations with the ratio of sodium bicarbonate and acid (citric acid : malic acid) as follows: formulation I = 2.5: (2:1), formulation II = 3: (2:1), formulation III = 3.5: (2:1). The results showed that, each 5g serving size contained 84.41 g of carbohydrate in the form of effervescent granules. In formula I, the test results obtained were pH 4.82, water content 4.14%, flow speed 11.58 g/second, angle of repose 25.36o, and dispersion time 28.91 seconds. Then, in formula II, the test resultedin pH 5.27, water content 3.80%, flow speed 12.39 g/second, angle of repose 26.69o and dispersion time 26.19 seconds. Moreover, the test findings for formula III, were pH 5.76, water content 3.86%, flow speed 11.83 g/second, angle of repose 26.63o and dispersion time 29.55 seconds. The differences between acid and base concentration ratio in the three formulas above affect the physical properties of effervescent granule preparations, with formula II producing the best carbonation of the three.

Lower back pain is a common complaint among pregnant women in the third trimester. It is estimated that approximately 70% of pregnant women experience some form of back pain during pregnancy, childbirth, or postpartum. Non-pharmacological therapies such as deep breathing relaxation techniques and effleurage massage therapy can effectively reduce pain levels in these women. This study employs a quantitative approach using a quasi-experimental research method and employs purposive sampling with a sample size of 37 participants. Data analysis includes both univariate and bivariate analyses. Most respondents (64.9%) were aged between 20 and 35 years old. Additionally, the majority (64.9%) were experiencing their first pregnancy. All respondents (100%) were confirmed to have no comorbidities. Furthermore, 73% of the participants had tertiary education (Diploma, Bachelor's, Master's, or Doctorate degrees), and 62.2% continued working during pregnancy. The results of the Wilcoxon test indicated a significant effect (p = 0.000 < 0.05), confirming that effleurage massage and deep breathing relaxation techniques effectively reduce lower back pain in pregnant women. This reduction is attributed to the stimulation of tactile fibers in the skin by effleurage massage, which inhibits pain signals. In conclusion, the findings suggest that implementing effleurage massage and deep breathing relaxation techniques is beneficial for alleviating lower back pain in pregnant women. Public health advice advocates for the application of these techniques to manage such pain effectively.

This study's objective is to evaluate PT. ABSD financial results. The method used in this study is descriptive qualitative. The study's findings indicate that the company's financial performance as seen in the balance sheet statement is deemed unhealthy due to the lower liquidity value in terms of balance sheet assets. However, because businesses can raise cash and lower financial risk, income statements are seen negatively. In summary, despite the fact that the gross profit margin is declining annually, the income statement's financial performance is deemed unhealthy.    

It cannot be denied that the digital era has developed greatly in today's society, especially among teenagers. All groups from children to the elderly are technologically literate because the world has begun to evolve. This allows people to enjoy and maintain their motivation in following existing technological developments, including the fields of social media and e-commerce which cannot be separated from the Internet. Media advertising using Internet technology or other technological media is commonly referred to as e-commerce, which has the advantage of being able to carry out buying and selling activities between sellers, and applications using Internet technology to make online purchases. Usually, the e-commerce widely used by business players is Shopee.The appearance of the website is attractive and easy to understand, which is an important thing for the public to pay attention to in e-commerce. Nowadays, small and medium-sized business stakeholders are beginning to realize that society is showing more interest in online shopping, as consumers are also embracing the development of digital pursuit technology and no longer need to go to a shopping place to get the goods they want, what is offered in e-commerce is no less competitive

Introduction: Low back pain is one of the most common musculoskeletal disorders in the world. In general, this pain is caused by muscle stretching and increasing age which will cause the intensity of exercise and movement to decrease. This will cause the back and abdominal muscles to become weak. Objective: In this study, to analyze the effect of warm compresses of red lemongrass (cymbopogon nardus) on reducing the scale of lower back pain in fishermen in Negeri Latuhalat, Nusaniwe District. Method: Using a one group pre test-post test design, this research design is included in the Pre-Experimental research type and the sample size is 56 fishermen using instruments in the form of SOPs and observation sheets. The analysis used is the Willcoxon test. Results: It was found that there was an effect of warm red lemongrass (Cymbopogon nardus) compresses on reducing the scale of lower back pain in fishermen (p-value = 0.000). Conclusion: There is an influence between the pain scale before and after being given a warm compress of red lemongrass (cymbopogon nardus) on reducing the scale of lower back pain in fishermen in Negeri Latuhalat, Nusaniwe District.  

Introduction Osteoarthritis (OA) is the most common articular disease of the developed country and cause of chronic disability, and may cause joint failure.Currently, it is more prevalent than it used to be, and it is predicted that this tendency will continue as life expectancy and the prevalence of obesity increase.OA is related to age, but is associated with a variety of both modifiable and non-modifiable risk factors, including obesity, lack of exercise, genetic predisposition, bone density, occupational injury, trauma, and gender. It is a major cause of disability in elderly populations around the globe, especially in developed countries. the aim of study to identify Knowledge about osteoarthritis and its related risk factors in fourth grade students in nursing department of Alfarabi collage  and to assess Knowledge about osteoarthritis and its related risk factors in fourth grade students in nursing department of Alfarabi collage . methodology The methodology for studying the knowledge about osteoarthritis and its related risk factors in fourth-grade students in the nursing department of Alfarabi College can be utilize a cross-sectional research design to assess the knowledge of fourth-grade nursing students about osteoarthritis and its related risk factors. A convenience sampling method will be used to select participants from the fourth-grade nursing students at Alfarabi College. The sample size will be determined based on the total number of fourth-grade students in the nursing department. Results The sociodemographic characteristics of 256 students at Al-Farabi College were analyzed. The majority of respondents were male (73.8%), over 22 years old (35.3%), and engaged in manual labor (53.0%). The study found that students had higher knowledge about certain aspects of osteoarthritis, such as postmenopausal women being more at risk for osteoporosis than osteoarthritis (87.5%), while their knowledge about female gender as a risk factor was lower (39.4%). Students also had higher knowledge about joint pain as a symptom of osteoarthritis (82.8%) compared to redness in the joint (53.1%).Finally, while there was a high significance between having a first-degree relative with knee osteoarthritis and knowledge, there was no significance between being clinically diagnosed with osteoarthritis and knowledge among the students. Conclusion  the study of sociodemographic characteristics and knowledge of osteoarthritis among students at Al-Farabi College revealed that there were significant associations between gender, occupation, awareness of knee osteoarthritis as a disease entity, and having a first-degree relative with knee osteoarthritis with knowledge about the condition. However, there was no significant association between age, being clinically diagnosed with osteoarthritis, and knowledge.

Porous concrete is commonly used in road linings with minimal traffic, parking areas, pedestrian paths, and parks. The strength of porous concrete depends on the size of the aggregate and the correct composition of water and cement. The objective of the study was to analyse the effect of cement water factor in uniformly graded porous concrete on compressive strength and permeability in uniformly graded porous concrete on permeability values. The relationship between the compressive strength of concrete tends to decrease as the value of cement water factor increases. The water-cement factor strongly influences the permeability value. The greater the value of cement water factor, the smaller the permeability of uniformly graded porous concrete, this is due to the deposition of cement water at the base of the slab. The use of super plasticizer (SP) in porous concrete accelerates the pavement process, but does not improve permeability. cement water factor 0.35 with a 28-day treatment period obtained a Slump test value of 178 mm, cement water factor 0.5 of 192 mm, cement water factor 0.6 with a 28-day treatment period obtained a Slump test value of 196 mm. while porous concrete with a cement water factor of 0.35 has an average compressive strength of 6.13 Mpa, while a cement water factor of 0.50 has an average compressive strength of 5.47 Mpa, and a cement water factor of 0.60 has an average compressive strength of 5.00 Mpa.

Hypertension, often called the "silent killer," is a leading non-communicable disease contributing to high mortality and morbidity, particularly in the elderly. As individuals age, peripheral blood vessel elasticity decreases, increasing vascular resistance and leading to systolic hypertension, commonly seen in older adults. Hypertension requires long-term treatment, which can result in non-compliance among elderly patients. Family support plays a crucial role in assisting and encouraging adherence to treatment regimens. This quantitative correlation study, with a cross-sectional approach, aimed to examine the relationship between emotional family support and treatment compliance in elderly hypertensive patients. The study was conducted at the Sei Agul Health Center, with a sample size of 65 elderly individuals selected using the Slovin formula and purposive sampling technique in October 2023. The Morisky Medication Adherence Scale (MMAS-8) was used to measure treatment compliance, while the emotional support instrument was developed by the researcher. Data were analyzed using the chi-square test, showing a significant relationship between emotional family support and treatment compliance (p-value < 0.05). The findings conclude that emotional support from family positively influences the compliance of elderly patients undergoing hypertension treatment at the Sei Agul Health Center. Health workers are encouraged to involve families in supporting hypertensive patients to enhance treatment outcomes.