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Allergic rhinitis (AR) is a chronic inflammatory disorder of the nasal mucosa mediated by immunoglobulin E (IgE) in response to allergen exposure. This condition has become a significant global health concern because of its increasing prevalence and substantial impact on quality of life, sleep, cognitive function, and work productivity. AR is also commonly associated with other atopic diseases, including asthma and atopic dermatitis. This article aims to review the current understanding of allergic rhinitis, focusing on epidemiology, pathophysiology, clinical manifestations, diagnostic approaches, and evidence-based management strategies. This study used a narrative literature review method by analyzing scientific articles, clinical guidelines, and peer-reviewed journals published between 2015 and 2025. Literature sources were obtained from PubMed, Google Scholar, and relevant medical databases using keywords related to allergic rhinitis, IgE, diagnosis, and immunotherapy. The findings indicate that allergic rhinitis involves complex immune mechanisms characterized by Th2 lymphocyte activation, IgE production, and inflammatory mediator release. Diagnosis is primarily established clinically and supported by allergy testing such as skin prick tests or serum-specific IgE measurement. Intranasal corticosteroids remain the first-line therapy for moderate to severe cases, while antihistamines and leukotriene receptor antagonists are used as adjunctive therapies. Allergen immunotherapy has shown effectiveness in modifying disease progression and improving long-term outcomes. In conclusion, allergic rhinitis is a manageable chronic disease that requires a comprehensive and individualized treatment approach involving environmental control, pharmacotherapy, and immunotherapy.

Chamomile flowers (Matricaria chamomilla) are known to have anti-inflammatory, antioxidant, and antipruritic properties that may be beneficial in the treatment of dermatitis, especially in children. Atopic and contact dermatitis are common skin conditions that often cause itching, inflammation, and discomfort. This study aims to evaluate the effectiveness of chamomile flowers in reducing dermatitis symptoms in children through a systematic literature review and meta-analysis. A literature search was conducted in the PubMed, Scopus, and Cochrane Library databases using relevant keywords. The analysis results indicate that topical application of chamomile extract significantly reduces inflammation and itching compared to a placebo and is nearly comparable to mild corticosteroids. However, further studies with larger sample sizes are needed to confirm its effectiveness and safety.

Allergic rhinitis (AR) is an atopic disease characterized by symptoms of nasal congestion, clear rhinorrhea, sneezing, postnasal drop, and nasal pruritis. The disease affects one in six people and is associated with significant morbidity, loss of productivity, and health care costs. Historically, AR was considered a disease process in the nasal airways only, although it is not serious, allergic rhinitis should be considered as a quite serious condition because it can affect the sufferer's quality of life due to the severity of the symptoms experienced and can also cause various complications. However, the development of integrated airway theory has classified AR as a component of the systemic allergic response, with other related conditions, such as asthma and atopic dermatitis, having an underlying systemic pathology. Even though it is not serious, allergic rhinitis should be considered as a quite serious condition because it can affect the sufferer's quality of life due to the severity of the symptoms experienced and can also cause various complications. In addition to nasal symptoms, patients with AR may also experience allergic conjunctivitis, non-productive cough, Eustachian tube dysfunction, and chronic sinusitis. Once diagnosed, AR can be treated in a variety of ways, with intranasal glucocorticoids being the first line of therapy.

Dermatitis is an inflammatory skin disease that is accompanied by itchy skin. It occurs in infants, and gets better in adolescence, but some cases can persist for a long time or even develop the disease in adulthood. In general, if you have this skin disease, you should see a skin specialist for a consultation. However, skin specialists are not always at the hospital, making it difficult for patients to arrange appointments to meet or consult. Therefore, the hospital needs to have an additional system that can help facilitate the medical team to detect the type of dermatitis disease based on symptoms (blistering skin, redness of the skin, scaly and dry skin, dark skin, blistering skin, cracked skin that is present in the disease, atopic dermatitis, contact dermatitis, seberoic dermatitis, nummular dermatitis, and intertriginous dermatitis and get handling and understanding of dermatitis disease using the certainty factor method. From the analysis carried out, the results of the diagnosis of the selected symptoms are obtained, the most accurate diagnosis is Atopic Dermatitis 98% with the treatment given, namely Corticosteroids and Antihistamines to patients.  

Pruritus, or itching, is a common symptom in seniors that has a significant impact on their quality of life. Primary skin disorders such as xerosis, atopic dermatitis, and scabies, as well as systemic diseases such as cancer, chronic renal failure, cholestasis, hyperthyroidism, diabetes mellitus, iron deficiency anemia, and certain medications, can cause this condition. Chronic pruritus, which is common in individuals over 60 years of age, can cause discomfort, sleep disturbances, and psychological stress. This activity uses the PDCA (Plan-Do-Check-Act) methodology to screen for pruritus intensity in the elderly in St. Anna. One individual (2.4%) reported mild pruritus, while 12 individuals (29.3%) reported severe pruritus. Routine assessment using the 12-PSS provides important information for managing pruritus in the elderly, meeting clinical and research needs, and improving patient care and quality of life.

Healthy skin is necessary for the body to provide active protection against changes in the environment. In order to preserve skin moisture and give protection from ultraviolet (UV) light, a healthy stratum corneum is mandatory. Several skin disease, including atopic dermatitis, contact dermatitis, ichthiosis, and psoriasis, are associated with anomalies in stratum corneum hydration. Meanwhile, erythema, photosensitivity, and skin cancer can all result from prolonged exposure to UV radiation. This study were done withis a cross sectional with non-random consecutive sampling. The parameters taken in this study include demographic (age and gender), skin moisture / moist (%) and sun damage / UV Damage (%). Thirty adolescents between 12-18 years were included in the study (20 male (66,7%), vs 10 female (33,3%). The mean facial moisture was 63.6 (± 14.72)%, and sun damage was 31.53 (±14.47)%. These data suggest that dry skin and UV skin damage can happen to anyone including teenagers. Therefore it is essential to maintain the skin moisture and protect it from UV radiation, to obtain healthy skin and prevent associated skin problems.    

Atopic dermatitis (AD) is a skin inflammation in the form of chronic, recidive dermatitis, accompanied by itching, and hitting certain parts of the body, especially on the face in the baby (infantile phase) and the flexible part of the extremities (in the child phase). Atopic dermatitis often occurs in infants and children, about 50% will disappear in adolescence, but sometimes it can also persist, or even only begin to appear in adulthood. The prevalence of AD is increasing and the increase in the incidence of AD is related to a history of atopy. The etiology of AD is not known with certainty, but it is known to be caused by the interaction of intrinsic and extrinsic factors in AD. Clinically, itching and skin disorders are found according to specific morphology and distribution. Risk factors that are proven to cause and induce AD are skin barrier disorders due to FLG mutations, environmental changes, and diet. FLG mutations can damage the skin barrier function with impaired pH and maintenance of skin hydration. It is known that the causes of multifactor AD and AD cannot be cured, however, only controlled. Therefore, preventive efforts are important, where doctors need to communicate with patients and their families, provide information and education on diseases, and how to treat and prevent recurrences. Because until now there is no ideal treatment regimen for AD patients, so thorough and appropriate management is needed, especially in reducing signs and symptoms, healing and preventing recurrences.