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Human Immunodeficiency Virus (HIV) infection leading to Acquired Immune Deficiency Syndrome (AIDS) remains a global public health issue, with 39 million people living with HIV worldwide in 2022. Although X Hospital in Malang City provides a comprehensive care program, internal data shows a significant level of non-adherence to antiretroviral (ARV) therapy, often in the form of irregular consumption or discontinuation of medication without medical recommendation. This observational study with a cross-sectional approach aims to identify the determinants of ARV non-adherence, involving 81 non-adherent AIDS patients at Hospital X through total sampling techniques. The characteristics of the respondents were dominated by males, highly educated, and working in the non-government sector, with the majority using the ARV regimen TLD, COTRIMOXAZOLE. The results of statistical analysis indicate that all eight determining variables tested show a highly significant positive correlation (p < 0.001) with non-compliance, meaning that the more severe the problems with these factors, the lower the patient compliance. Furthermore, the top five factors showed a very strong positive correlation (r > 0.80) with non-adherence, namely motivation/depression, social support, communication with service providers, treatment costs, and age or routine. These findings underscore that these five key determinants must be a crucial focus in designing and implementing targeted intervention strategies to effectively improve patient adherence to ARV therapy.

Background: HIV is a virus that targets the human immune system. It can spread through sperm or vaginal fluid during intercourse, needles from infected individuals, or blood. The virus is more accurately known as a syndrome, which is a group of symptoms from different illnesses and infections. The term ODHIV (People with HIV) refers to individuals who are infected with HIV. Objective: To determine the effect of self-care educational videos on the knowledge and motivation of antiretroviral (ARV) adherence for people living with HIV (PLHIV). Method: The research uses a quantitative type of research with one group pre-post test design experiment. The sample consisted of 76 respondents. Sampling was determined using the Lemeshow formula technique. The data obtained were analyzed by using the Mann-Whitney test. Result: The results of the Mann-Whitney test means that there is an influence in providing knowledge and motivation for antiretroviral adherence in educational videos about HIV. Conclusion: There is an influence of self-care educational videos on the knowledge and motivation of antiretroviral (ARV) adherence for people living with HIV (PLHIV).

Human Immunodeficiency Virus (HIV) is a disease that attacks the body's immune system so that it is unable to fight various diseases. Communities with low levels of health literacy will face more problems. According to the Central Java Provincial Health Service, the number of HIV sufferers has also increased rapidly to Central Java, Semarang City with 331 cases, and the majority of those infected are men. The general aim of this research is to determine the relationship between health literacy and adherence to taking antiretroviral drugs (ARV) in people living with HIV (PLHIV). This research is a type of non-experimental descriptive analytical research with a cross-sectional approach. The samples taken were all patients with HIV (PLHIV) who took ARV drugs in the work area of ​​the Poncol Health Center, Semarang City. The technique used was consecutive sampling of 83 people. The correlation test used in this research is the chi-square test. From the results of the analysis, it was found that of the 83 research respondents, there was a relationship between the health literacy of people living with HIV (PLHIV) and the use of antiretroviral drugs (p value 0.003). The research results showed that the majority of respondents had high health literacy and were compliant with medication consumption with a total of 55 respondents (96.5%).