Publication Search

The development of modern biotechnology has brought fundamental changes to the life sciences through the application of molecular biology, genetic engineering, and bioinformatics techniques. This article aims to examine the transformation of life sciences through modern biotechnology approaches and its impact on health, agriculture, the environment, and industry. The method used is a descriptive-analytical literature review based on international journal sources and relevant scientific publications. The results of the study indicate that technologies such as CRISPR-Cas9 enable precise gene editing for genetic disease therapy, while the mRNA vaccine platforms developed by Pfizer and Moderna demonstrate the acceleration of biomedical innovation in response to the global pandemic. In the agricultural sector, genetic engineering increases crop productivity and resilience, while in the environmental sector, biotechnology supports environmentally friendly bioremediation processes. However, ethical and regulatory challenges remain important concerns in its implementation. In conclusion, modern biotechnology plays a key role as a catalyst for sustainable, innovation-driven transformation in the life sciences.

The development of lanthanum-doped barium hexaferrite materials has attracted considerable attention in the field of functional materials, particularly as electromagnetic wave absorbers. This literature review aims to analyze advances in synthesis methods, structural characteristics, magnetic properties, and electromagnetic absorption performance of lanthanum-doped barium hexaferrite reported in various studies. Synthesis techniques such as sol–gel, coprecipitation, solid-state reaction, and hydrothermal methods are compared to evaluate their effects on crystallite size, morphology, and phase purity. Lanthanum doping is known to modify lattice parameters, reduce coercivity, and enhance complex permittivity and permeability, which play crucial roles in absorption mechanisms. Furthermore, variations in dopant concentration significantly influence reflection loss values and effective absorption bandwidth. The reviewed literature indicates that optimization of composition and synthesis routes can produce materials with high absorption capability, good stability, and strong potential for application in electromagnetic interference mitigation devices. This review is expected to serve as a conceptual reference for future development of lanthanum-doped barium hexaferrite–based electromagnetic wave absorbing materials. The comparative approach also highlights research challenges, industrial application opportunities, and future research directions relevant to the evolving demands of modern communication and defense technologies at both national and global levels.

This study comprehensively evaluates the quality of biomass briquettes produced from blends of coconut shell charcoal and sengon sawdust, using both carbonized and non-carbonized materials. Composite briquettes were fabricated with varying compositions and characterized through proximate analysis, calorific value, density, and burning rate measurements to determine their suitability as solid fuel. The results indicate that adding non-carbonized sawdust increases volatile matter content and burning rate but reduces the calorific value of the briquettes. In contrast, incorporating up to 10% carbonized sawdust significantly improves the calorific value to 6119.2 cal/g, approaching that of pure coconut shell charcoal (6352.2 cal/g), while maintaining a relatively high burning rate. Briquettes containing carbonized sawdust also exhibit low ash content, below 3%, and moisture content under 8%, meeting standard solid fuel quality requirements. These findings demonstrate that a strategic combination of carbonized and non-carbonized materials can produce hybrid biomass briquettes with optimized thermal performance, providing a promising, sustainable, and environmentally friendly alternative fuel for domestic and industrial applications.

The discharge of surfactant-laden wastewater from the rapidly expanding laundry industry poses significant environmental risks, especially in densely populated urban areas. While constructed wetlands (CWs) and Eco-Enzyme technology have shown promise for surfactant remediation, their standalone application requires long hydraulic retention times (HRTs), limiting practical implementation. This study evaluated the efficacy of a novel integrated system combining a subsurface constructed wetland (SSFCW) with fruit peel-derived Eco-Enzyme to treat synthetic laundry wastewater. Over a 6-day treatment period, the combined system achieved a remarkable surfactant removal efficiency of 99.63%, reducing the concentration from 225 mg/L to 0.835 mg/L—well below the regulatory threshold of 3 mg/L. The synergistic degradation mechanism involves enzymatic hydrolysis via Eco-Enzyme lipase and protease activity, complemented by microbial mineralization in the wetland rhizosphere. This system maintains optimal environmental conditions, with a stable pH of 6.85-7.32 and a temperature of 30.9-35.2°C, supporting robust biological activity. These findings demonstrate that the integrated Eco-Enzyme/SSFCW system overcomes the limitations of conventional HRT approaches, offering a highly efficient, sustainable, and practical decentralized wastewater treatment solution for the laundry industry.  

Histology practicum, as one of the compulsory practicum courses, offers a great opportunity to practice various aspects of science process skills through microscopic tissue observation activities, identification of cell and tissue structures, and analysis of tissue functions in organisms. This study aims to analyze the science process skills biology education students through histology practicum activities. This study uses a quantitative descriptive approach with a survey method to analyze the science process skills of biology education students through histology practicum activities. Data collection in this study used three main techniques, namely science process skills tests, direct observation, and analysis of practicum report documents. Furthermore, the data were analyzed descriptively quantitatively using descriptive statistics to describe the profile of students' science process skills. Analysis per aspect revealed that students had good skills in the aspects of observing (78.50%), classifying (76.33%), interpreting data (71.67%), applying concepts (73.25%), and communicating results (73.40%), which indicates that histology practicum is effective in developing basic science process skills. However, the aspects of formulating hypotheses (58.17%) and planning experiments (54.83%) were still in the sufficient category, indicating that students experienced difficulties in integrated science process skills that require higher-order thinking skills. The findings this study provide important implications for the development of more comprehensive histology practicum learning strategies, including the integration of inquiry approaches, the use of continuous formative assessment, the application of differentiated learning, and strengthening the connection between theory and practice to optimize the development of all aspects of science process skills of prospective biology teachers.  

Rainfall plays a crucial role in determining flood risk, particularly in regions with high precipitation intensity and limited drainage capacity. Langkat Regency in North Sumatra is one of the areas frequently affected by seasonal flooding. This study aims to model the spatial distribution of rainfall and estimate the rainwater volume using the double integral approach as a basis for flood mitigation planning. Monthly rainfall data from various observation stations in 2024 were processed to obtain the average rainfall intensity, which was then converted into meters and multiplied by the total area of Langkat Regency to compute the rainwater volume. The results indicate that the total estimated rainwater volume throughout 2024 reached 16,409,819,800 m³, with peak precipitation occurring from September to November, contributing significantly to the increasing flood risk in low‐lying zones and riverine areas. These findings demonstrate that the use of double integrals is an effective quantitative method for predicting potential flood volume based on rainfall distribution. The outcomes of this study are expected to serve as a scientific reference for local governments in developing data-driven flood mitigation strategies, such as improving drainage capacity, constructing retention basins, and strengthening watershed management.

This study aims to analyze the implementation of video animation-based flipped classroom learning model in increasing students' learning interest in science subjects with material on the structure and function of living organisms in class 8D at SMPN 1 Sanrobone. The low interest in learning science among students is a major problem that needs to be addressed through more attractive and interactive learning innovations. The video animation-based flipped classroom model was chosen because it can optimize classroom learning time for more meaningful activities, while basic concept understanding is done independently through engaging animated videos. This study uses a survey method with a descriptive quantitative approach. The research subjects were  students of class 8D SMPN 1 Sanrobone in the even semester of the 2024/2025 academic year. Research instruments used learning interest questionnaires, observations, and documentation. The results showed that the implementation of video animation-based flipped classroom model was able to increase students' learning interest with high categories in aspects of attention, interest, involvement, and learning satisfaction. Animated videos presented before face-to-face learning provide clear visualizations of the structure and function of living organisms, making students more prepared and enthusiastic to participate in discussions and practical activities in class. This learning model also encourages student learning independence and increases active interaction in learning. This study recommends the implementation of video animation-based flipped classroom as an alternative effective and innovative science learning strategy to increase students' learning interest.

This research extends the previous work of Tsaqila, Winiarti, and Widaningrum (2024), who applied the Complex Proportional Assessment (COPRAS) method within a decision support system for supermarket branch location selection. Unlike the prior study, which focused on Ponorogo through a web-based framework, this study expands the implementation of COPRAS to the Medan Area, Medan Kota, Medan Polonia, dan Medan Maimun districts, adapting it to local urban, social, and economic characteristics. The main objective is to identify the most strategic site for a new supermarket by analyzing multiple criteria, including land cost, population density, accessibility, safety, cleanliness, and disaster risk. Data were collected from both field surveys and official government publications. The findings reveal that the COPRAS method provides reliable and objective assessments among the evaluated alternatives, with Medan Area emerging as the most suitable location for supermarket development. Overall, this study broadens the practical scope of the COPRAS method in a different regional context and reinforces its reliability and adaptability as a multi-criteria decision-making tool in the modern retail industry.

That Christian Religious Education teachers update their professionalism and competencies to ensure that Christian education remains relevant, effective, and transformative. This study aims to analyze the modernization of the professionalism of Christian Religious Education teachers, including the integration of spirituality with modern pedagogical approaches and strategies for developing teacher competencies in addressing the challenges of the digital generation. The study employs a descriptive qualitative approach, collecting data through literature review from books, journals, notes, and relevant reports, and presenting the findings in a narrative form. The results show that the modernization of teacher competencies involves the development of pedagogical, personal, social, spiritual, and professional competencies, with the ability to integrate spirituality, technology, and modern teaching methods such as collaborative and digital learning to create contextual, engaging, and transformative learning experiences. In conclusion, the modernization of professionalism among Christian Religious Education teachers is an urgent necessity to enable teachers to deliver God’s Word in a relevant manner, shape students’ character and spirituality, and enhance the effectiveness of Christian education through mastery of holistic and collaborative competencies.  

Increasing traffic activity at unsignalized intersections often results in congestion and delays. The intersection of Jl. Imam Bonjol and Jl. Daya Nasional experiences these conditions, making performance evaluation necessary. This research tends to scrutinize the intersection performance under existing conditions and five-year projected conditions and to identify appropriate improvement measures. The analysis was carried out using the 2023 Indonesian Road Capacity Guidelines (PKJI 2023) and PTV VISSIM microsimulation software. Data on intersection geometry, vehicle speed, and traffic volume were collected through CCTV observations on weekdays and weekends. The results show that under existing conditions, the degree of saturation reached 1.170 with an average delay of 33.75 seconds (LOS D). In the five-year projection, the degree of saturation increased to 1.239 with an average delay of 53.69 seconds (LOS E). These findings indicate a decline in intersection performance, highlighting the need for alternative traffic management measures to improve operational performance and service levels.    

This study examines the renewal of the Criminal Procedure Code (KUHAP) Baru as an effort to synchronize with the Criminal Code (KUHP) 2023, as well as analyzing crucial articles that potentially cause legal uncertainty in the criminal justice process in Indonesia. Using a juridical-normative method with a descriptive-analytical approach, this research analyzes secondary data from primary, secondary, and tertiary legal materials. The results show that KUHAP Baru successfully addresses some of the mismatches with KUHP 2023 through regulations on alternative punishments, corporate accountability, and protection for vulnerable groups, but still faces conceptual and technical challenges such as legislative disharmony and minimal public participation. On the other hand, crucial articles such as Articles 5, 16, 74, 90, 93, 105, 112A, 124, 132A, and 137A pose risks of legal uncertainty due to the expansion of law enforcement authority without adequate oversight, which can violate the due process principle and human rights. The study's conclusion emphasizes the need for further revisions to strengthen legal certainty and harmonize the criminal justice system.

Introduction: Dental and oral health problems in school-age children are still a major public health concern. The Little Doctor Program is a school-based health promotion approach that involves the active role of students as agents of change. This study aims to analyze the effectiveness of Small Doctors in promoting dental health in elementary schools. Methods: This study used a quasi-experimental design with a one group pretest–posttest approach. The subjects of the study were elementary school students who participated in dental health promotion activities by Small Doctors. Interventions include counseling, demonstrations of proper brushing of teeth, and the use of educational media. Data were collected using a questionnaire of dental health knowledge, attitudes, and behaviors before and after the intervention. Data analysis was carried out using the paired t-test or Wilcoxon test with a significance level of p < 0.05. Results: There was a significant improvement in students' dental health knowledge, attitudes, and behaviors after the intervention (p < 0.05). Conclusion: The Small Doctor Program is effective as a strategy for promoting dental health in elementary schools and has the potential to support promotional and preventive efforts for children's dental health.

The JKN Mobile application is an electronic-based service innovation introduced by BPJS Health to facilitate JKN participants in accessing healthcare services and managing their membership information. This study aims to explore the experiences and perspectives of outpatient patients regarding the effectiveness of the JKN Mobile online registration system at Baubau City Regional General Hospital. A qualitative phenomenological approach was employed, with informants selected through purposive sampling. Data were collected to capture the meanings of patients’ experiences in using the application. The findings show that most patients are satisfied with the practicality, speed, and flexibility of the online registration system. However, technical problems, particularly unstable internet connectivity, remain a major challenge. Furthermore, the online registration system has contributed to improved service efficiency and patient satisfaction. These findings indicate the importance of continuous evaluation and improvement of the JKN Mobile online registration system to enhance service quality and health information system development at Baubau City Regional General Hospital.

Antenatal Care (ANC) is a health service provided to pregnant women during pregnancy by healthcare professionals in accordance with established standards, one of which is the implementation of the 10T ANC service components. The quality of ANC services plays an important role in determining pregnant women’s satisfaction, which in turn affects their compliance with antenatal visits and the effectiveness of pregnancy monitoring. Maternal satisfaction is an essential indicator for assessing the quality of healthcare services at primary healthcare facilities. This study aimed to examine the relationship between 10T Antenatal Care services and pregnant women’s satisfaction at Biru-Biru Public Health Center in 2025. This research employed a quantitative method with an analytical design using a cross-sectional approach. The sample was selected through purposive sampling, involving 48 third-trimester pregnant women. Data were collected using questionnaires that assessed the implementation of 10T ANC services and the level of maternal satisfaction. The collected data were analyzed statistically to determine the relationship between the variables. The findings of this study are expected to provide insights into the importance of optimal implementation of 10T ANC standards. Therefore, healthcare providers, particularly midwives, are encouraged to continuously improve the quality of ANC services to enhance pregnant women’s satisfaction and support efforts to improve maternal and child health outcomes.

The mathematics learning outcomes of students at SMP Negeri 3 Bontang on Rational Numbers are still relatively low. Data from the 2019 National Examination (UN) shows an average math score of 46.43, which is in the "poor" category. Summative assessment results indicate that most students have not yet achieved the Learning Objective Achievement Criteria (KKTP). This situation indicates that the learning process tends to be conventional and lacks active student engagement. Therefore, a more innovative learning model is needed, one of which is the Team Games Tournament (TGT), which combines group work, competition, and educational games. This study aims to determine the effect of the TGT learning model on the mathematics learning outcomes of seventh-grade students at SMP Negeri 3 Bontang in the topic of Rational Numbers. This study used a quantitative approach with a quasi-experimental type and a Posttest-Only Control Group Design. The study population was 203 seventh-grade students in the 2024/2025 academic year, with a sample consisting of class VII A as the experimental group (33 students) and class VII F as the control group (34 students), selected through a purposive sampling technique. The research instrument was a five-item essay test. The analysis results showed that the average posttest of the experimental group was 67.848, higher than the control group at 61.794. The Independent Sample t-Test produced a significance value of 0.031 <0.05, so H₀ was rejected. This indicates that the Team Games Tournament (TGT) learning model has a significant effect on improving students' mathematics learning outcomes in the Rational Numbers material.

This study investigates the effectiveness of a multimodal approach in improving students’ English reading comprehension at SMPN 10 South Tangerang during the 2025/2026 academic year. Involving 42 eighth-grade students, the research aimed to determine whether integrating various modes of learning—such as text, images, audio, and video—could enhance reading comprehension more effectively than traditional text-based instruction. A pre-experimental one-group pre-test and post-test design was used to measure students’ progress before and after the implementation of multimodal learning. Data were analyzed using a paired sample t-test to identify significant differences between the two tests. The results indicated a notable improvement, with the mean score increasing from 70.48 on the pre-test to 79.76 on the post-test, representing a gain of 9.28 points. The significance value (Sig. 2-tailed = 0.000) confirmed that the improvement was statistically meaningful. These findings demonstrate that multimodal instruction enhances comprehension by presenting information through multiple sensory channels, supporting diverse learning preferences, and creating a more engaging and interactive learning environment. The study concludes that the multimodal approach is an effective method for teaching reading comprehension in junior high school and recommends broader application in English classrooms to strengthen students’ motivation, understanding, and overall learning outcomes.

The development of science and technology has encouraged the utilization of graph theory in solving optimization problems, particularly in transportation systems and tourism route planning. Medan City, as a metropolitan area with dense road networks and widely dispersed tourist destinations, faces challenges in selecting efficient travel routes. This research aims to determine the optimal route between tourist destinations in Medan City using the Minimum Spanning Tree (MST) method with Prim’s Algorithm. The research was conducted using a weighted graph modeling approach, where each tourist destination is represented as a vertex and the distance between destinations is represented as an edge weight. Distance data and estimated travel time were obtained through digital mapping using Google Maps and then analyzed through iterations of Prim’s Algorithm to produce a minimum spanning tree without forming cycles. The results show that all 23 tourist destinations are successfully connected in a single MST structure with a minimum total distance of 68.97 km and a travel time of approximately 199 minutes or 3 hours and 19 minutes. This model is expected to serve as a reference for tourism planning and support urban transportation efficiency based on mathematical computation.

Character development and independence in early childhood constitute fundamental foundations for future life success. While both the Montessori method and role-playing activities have proven effective in early childhood education, research on their integration remains limited. To analyse the effectiveness of integrating the Montessori method with role-playing activities in enhancing character development and independence in early childhood. A quantitative study employing quasi-experimental design with pre-test and post-test control group design was conducted with 60 children aged 4-6 years. Participants were randomly assigned to an experimental group (n=30, receiving the integrated method) and a control group (n=30, receiving conventional instruction). Significant improvements were observed in both character development (p<0.05) and independence (p<0.01) in the experimental group. The experimental group showed substantial gains in character scores (18.94 points) compared to the control group (4.36 points), with large effect size (Cohen's d = 2.06). Independence scores increased by 21.23 points in the experimental group versus 4.47 points in the control group, also with a large effect size (Cohen's d = 2.65). The integration of Montessori method with role-playing activities proves highly effective in enhancing character development and independence in early childhood, offering a promising pedagogical approach for early childhood education.

The rapid advancement of digital technology has significantly transformed the economic landscape, particularly in payment systems that are shifting from conventional cash transactions to the use of Electronic Money (E-Money). E-Money has become increasingly popular due to the convenience it offers, allowing users to conduct transactions anytime and anywhere without the need to carry physical cash. As this payment innovation continues to expand, it is essential to examine whether its mechanisms comply with Islamic principles, given that the use of E-Money is closely related to the values of muamalah in Islam. This study aims to identify the underlying contractual structure (akad) governing Mandiri E-Money transactions and to assess its conformity with sharia principles. It further analyzes the potential presence of gharar, riba, or maisir within the top-up and transaction processes, as well as the sharia mitigation mechanisms that may be applied. The research employs a normative approach based on classical and contemporary Islamic legal theory, supported by observational analysis of Mandiri E-Money practices. Data were analyzed qualitatively using a descriptive method and maqashid al-shariah reasoning. The findings indicate that the use of Mandiri E-Money does not involve elements of riba, gharar, or maisir, and therefore does not deviate from sharia principles. These potential risks were examined through fiqh legal maxims and DSN-MUI fatwas to ensure comprehensive sharia compliance.

The purpose of this study was to evaluate the application of the Deep Learning approach in teaching mathematics in the first grade of addition and subtraction of numbers 1 to 20 in a story problem through the concrete media Si PONPEL and the educational game Quizizz Paper Mode. This technology-based learning is intended to make learning more interactive and enjoyable, but does not require personal digital devices. Qualitative and quantitative data were collected through a mixed-method research design to measure student understanding the result show that the Si PONPEL and Quizizz Paper Mode methods successfully improved students’ understanding of basic mathematical concepts, with an average increase in student scores of 38.33%. In addition, findings from interviews conducted with teachers and students showed that the Si PONPEL concrete media and this technology made students more engaged and motivated to learn. It is hoped that this research will make a significant contribution to creating more inclusive and interactive mathematics kearning in elementary schools.