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Character education serves as a fundamental pillar in shaping a generation of morally upright, responsible, and resilient youth. It not only fosters ethical behavior but also equips children with the skills and attitudes necessary to contribute positively to society. This study aims to evaluate the implementation of character education among children through a combination of artistic activities—such as coloring and calligraphy—and environmental activities, specifically planting. The research was conducted in two orphanages located in Blitar Regency, namely Raudhatul Aitam Orphanage and Nurul Falah Orphanage. A descriptive qualitative method was employed, with data collected through observation, in-depth interviews, and documentation. The findings reveal that creative, participatory, and collaborative approaches are effective in nurturing essential character values among children, both under and over the age of ten. The core values instilled through the activities include appreciation for global diversity, cooperative spirit (gotong royong), faith, and environmental awareness. Practical activities, such as coloring illustrations of traditional houses, planting chili plants, and coloring calligraphic artworks, were found to enhance children’s creativity, self-confidence, patience, and social interaction skills. Moreover, these activities encouraged teamwork and a sense of responsibility, as children worked together to complete tasks and care for their environment. The study highlights the importance of integrating cultural, artistic, and ecological elements in character education programs to create engaging and meaningful learning experiences. Furthermore, continuous support and collaboration from various stakeholders—including caregivers, educators, community members, and government institutions—are essential to ensure sustainability. When consistently implemented, such programs have the potential to produce long-term positive impacts, helping children grow into individuals who are not only skilled and creative but also possess strong moral values and a deep sense of social responsibility.

Maintaining employee engagement presents a significant challenge for organizations, particularly when dealing with Generation Z, who possess unique characteristics, strong technological orientation, and high expectations regarding fairness in the workplace. One crucial factor believed to influence the level of employee engagement is organizational justice. This concept encompasses employees’ perceptions of fairness in the distribution of outcomes (distributive justice), the procedures applied (procedural justice), interpersonal treatment (interpersonal justice), and the clarity of information provided (informational justice). This study aims to examine the contribution of organizational justice to employee engagement among Gen Z employees at the Habepro Radionet Indonesia network. The research employed a quantitative approach with a simple linear regression method. The study population comprised all permanent Gen Z employees working within the network, with a sample size of 35 respondents. Data were collected using an organizational justice questionnaire covering its four dimensions and the Employee Engagement Scale (EES) to measure engagement levels. Data analysis was conducted using SPSS software through a simple linear regression test. The results revealed that organizational justice has a significant effect on employee engagement (p < 0.05), with a coefficient of determination of 0.528. This indicates that 52.8% of the variation in employee engagement can be explained by perceptions of organizational justice, while the remaining percentage is influenced by other factors beyond the scope of this study. These findings highlight the strategic importance of implementing fairness principles within organizations to enhance employee engagement, especially among Gen Z employees who tend to be more sensitive to equitable treatment, transparency of information, and open communication. Therefore, organizations are encouraged to design policies, procedures, and workplace interactions that foster a sense of justice, thereby sustaining employee engagement and contributing positively to overall organizational performance.

The objective of this mentoring activity is to increase the capacity of swimming pool managers, particularly in strengthening management and sustainable management strategies. With this increased capacity, it is hoped that Tirta Arum Swimming Pool can develop into a valuable village asset, both economically and socially. The swimming pool will not only provide a source of income for the village but also serve as a means of recreation, education, and social interaction for the surrounding community. The method used in this mentoring activity is Participatory Rural Appraisal (PRA), an approach that emphasizes active community participation in every stage of the planning process, decision-making, and program implementation. PRA enables village communities, including Tirta Arum Village-Owned Enterprise (BUMDes) managers, to analyze their environmental conditions, identify problems, and design contextual and sustainable solutions. This approach is implemented through structured mentoring, education, and training activities. Direct community involvement aims to foster a sense of ownership and responsibility for swimming pool management. In addition, with training tailored to local needs, managers are expected to be able to apply effective management principles, from planning and financial management to customer service and promotional strategies. Thus, the results of this activity are not only temporary improvements, but also long-term empowerment that contributes to the independence and business aspirations of the Village-Owned Enterprise (BUMDes). Through the PRA method, this activity not only provides an immediate solution to swimming pool management problems but also increases the independence of the community and managers in developing and operating the business sustainably. This increased community participation is expected to foster a sense of ownership (a sense of belonging) towards the swimming pool as a shared property.

Involvement across generations in church worship remains a significant challenge in building a solid and inclusive congregation community. At GKSI Sui Deras Estate, worship tends to be divided according to age groups, which limits spiritual interaction between generations. This creates a gap between younger and older congregation members, ultimately affecting the harmony and cohesion of the community. This community service program aims to optimize intergenerational worship as an effort to strengthen social and spiritual cohesion among the congregation by fostering mutual respect and enhancing relationships between generations. The activities began with an initial observation to identify the issues and needs of the congregation concerning worship. Based on the observation findings, a worship design was created involving representatives from various age groups, ensuring that each generation could feel included in the worship experience. This design process also took into account aspects that could bridge generational differences, such as the selection of hymns, liturgical readings, and approaches that were appropriate for different age groups. In addition, intergenerational liturgy training was conducted to ensure that worship could proceed harmoniously, with active participation from all age groups, from children to the elderly. Intergenerational worship was conducted periodically, providing opportunities for the entire congregation to interact and experience unity in worship. The results of these activities showed a significant increase in participation from congregation members of various ages. A sense of mutual respect between generations grew, something that had previously been lacking. This intergenerational worship also contributed to the strengthening of the community's identity as one body in Christ, where every member, regardless of age, felt valued and involved. Overall, intergenerational worship has proven to be a relevant and practical approach to strengthening the congregation community in a sustainable way, creating a more inclusive and loving atmosphere among fellow congregation members.

The purpose of this study was to determine the care skills of nurses. In carrying out their profession, care is required to improve skills which is a process that leads to professionalism. The process begins with the perception of nurses in seeing conditions and solving problems, one of which is carrying out the application of nursing care to clients. The application of nursing care provided by nurses cannot be separated from spiritual aspects which are an integral part of the nurse's interaction with clients. Nurses together with special spiritual officers in the hospital try to help meet the spiritual needs of clients as part of the client's overall needs, among others by facilitating the fulfillment of these client needs, even though nurses and clients do not have the same beliefs and religions. In the application of spiritual nursing care is influenced by several factors, namely intellectual skills where the nurse's intellect will be very influential in the application of care. With data collection methods, namely observation, documentation and questionnaires. The population and sample are Samples In this study, the sampling technique used was purposive sampling, namely the sample taken was 50 nurses who served in four rooms of the Inpatient Hospital Labuang Baji Makassar.

As technology rapidly advances and social media adoption becomes widespread, Instagram and TikTok have evolved into essential marketing platforms, particularly for Micro, Small, and Medium Enterprises (MSMEs). This report aims to develop and implement a digital marketing strategy for the Seblak Opat Lima MSME using these two platforms. The business faced challenges in optimizing its digital marketing to reach a broader market, primarily due to a limited understanding of digital marketing among employees and a lack of consistency in social media account management. Our methodology involved field observation, which included creating a content timeline and content scripts to ensure consistency and relevance of published material. The analysis results show a significant increase on both social media platforms after the strategy was implemented, with a growth in followers and enhanced audience engagement, especially on TikTok and Instagram. Furthermore, analytics indicate that trend-aligned content combined with appropriate hashtag usage successfully expanded reach, increased profile visits, and encouraged more active audience interaction. Thus, the implemented digital marketing strategy proved effective in expanding the market and boosting sales for Seblak Opat Lima MSME.

Digitalization has become a necessity across all sectors, in line with the rapid development of digital technology and the shift towards Society 5.0. The use of digital technology is now a crucial aspect in various activities, including the economic, social, and educational sectors. In the economic sector, in particular, the implementation of electronic data interchange (EDI) and the use of social media in marketing strategies have expanded to various business sectors, including micro, small, and medium enterprises (MSMEs). The shift in interaction patterns between consumers and sellers towards digital is both a challenge and an opportunity for MSMEs. However, the reality on the ground shows that most MSMEs in the regions, particularly in Sumbawa Regency, still experience gaps in digital literacy and human resource readiness in managing information technology. To address this challenge, digitalization outreach and training activities are being conducted for MSMEs and the general public in the region. These activities aim to improve understanding and basic skills related to the use of digital technology in running and developing businesses, such as online marketing, digital data management, and the use of e-commerce platforms. This outreach also emphasizes the importance of adapting to technological developments to increase the competitiveness and sustainability of MSMEs in the digital era. The results of this activity showed a 3% increase in participants' understanding of digitalization, as evidenced by a comparison of pre-test and post-test results. While this improvement is initial and modest, it reflects positive changes that can be further developed through follow-up programs and ongoing mentoring. Therefore, community empowerment through digital education is a strategic step in strengthening the role of MSMEs as key drivers of the local and national economy in the digital era.

Preeclampsia is a severe pregnancy complication characterized by hypertension and signs of organ damage, with a multifactorial etiology involving maternal, genetic, and environmental interactions. This study aims to analyze determinants contributing to the occurrence of preeclampsia through a comprehensive literature review. The research method involved an in-depth analysis of 15 scientific journals, consisting of 8 national publications from Google Scholar and 7 international publications from PubMed, selected based on relevance, credibility, and publication date. Data from these sources were synthesized to identify common risk factors, biological mechanisms, and preventive measures. The findings indicate that the primary risk factors for preeclampsia include a history of chronic hypertension, obesity, gestational diabetes, nulliparity (first pregnancy), and a family history of preeclampsia. Nutritional deficiencies, particularly low calcium and vitamin D intake, are also significantly associated with increased risk. Furthermore, immunological factors such as abnormal maternal immune tolerance, as well as placental dysfunction leading to poor perfusion, play a crucial role in the pathogenesis of preeclampsia. The interplay between these factors suggests that preeclampsia is not caused by a single mechanism, but rather by a complex network of physiological, metabolic, and genetic influences. This complexity underscores the importance of early risk factor identification and intervention strategies during antenatal care. Preventive efforts may include nutritional supplementation, weight management, blood pressure monitoring, and targeted medical interventions for high-risk individuals. In conclusion, preeclampsia remains a significant contributor to maternal and perinatal morbidity and mortality worldwide. Understanding its determinants enables healthcare providers to implement timely preventive measures and reduce its negative impacts on both mother and fetus. Further research is warranted to elucidate the precise mechanisms underlying these determinants, potentially paving the way for more effective prevention and treatment strategies.

Pharmacology is the study of drug interactions with living organisms. This study aims to evaluate the anti-inflammatory effects of several drug preparations, including Hemilon (methylprednisolone), Lupred (prednisolone), Kamathasone (dexamethasone), neem leaf infusion, and snakehead fish extract, on mice (Mus musculus) induced with inflammation using carrageenan solution via intraplantar injection. Edema volume was observed using a plethysmometer at 15, 30, 45, and 60 minutes post-induction. Data were analyzed using normality, homogeneity, ANOVA, and Tukey tests via SPSS. Results showed that Hemilon had the highest anti-inflammatory effect, followed by Kamathasone and Lupred, while neem leaf and fish extract showed weaker activity. Statistical tests revealed normal distribution (sig. 0.197 > 0.05), non-homogeneous data (sig. 0.022 < 0.05), and no significant difference between groups (ANOVA sig. 0.366 > 0.05). Despite this, descriptive results confirmed strong anti-inflammatory potential of synthetic drugs. This practicum provides valuable insights into drug mechanisms and emphasizes methodological accuracy in pharmacological testing.

Children in orphanages often face unique challenges in character formation due to limited educational stimulation and diverse social interactions, despite their basic needs being met. The interactive education model applied in the "Devotion in Action, Love in Education: Weaving Character with the Nation's Children" project focuses on a participatory approach through activities such as Story Telling, "Tree of Goodness," Ball Relay, and Water Balloon Volleyball. This research aims to analyze the effectiveness of implementing an interactive education model in the character development of children at Sabilul Muhtadien Orphanage in Plosokerep, Sananwetan District, Blitar City. The research method employed is a case study with a qualitative approach, reinforced by participatory observation and informal interviews with caregivers and children from the orphanage. The results indicate high enthusiasm from the children and positive responses from caregivers, signifying the program's success in instilling character values such as critical thinking, mutual cooperation, creativity, independence, and solidarity. The implications of this research highlight the importance of adopting dynamic and activity-based education models in efforts to shape children's character in orphanages, focusing not only on knowledge transfer but also on direct experience and holistic potential development. holistik.

This community service activity focuses on improving the competitiveness of A.A Transport, a business that lacks cashless payment options and an effective social media marketing strategy. Providing cashless payments is a modern, customer-centric approach that differentiates businesses in a competitive market. Unfortunately, A.A Transport currently lacks such an option, providing an opportunity for improvement. This community service activity aims to assist A.A Transport in adopting cashless payment methods and the importance of effective social media marketing for MSMEs. Social media serves as a direct channel for interaction, building relationships, and expanding the market. The methods used in this community service activity were observation, interviews, surveys, and mentoring. The results achieved are in line with the project objectives, as A.A Transport successfully integrated QRIS for cashless payments and utilized social media effectively for marketing, thus contributing to its competitiveness and overall market reach.

The purpose of this article is to describe the perceptions of physical education teachers and class teachers towards the role of physical education in improving the emotional well-being of elementary school students. The main focus of the discussion is how PJOK lessons not only have an impact on physical development, but also support students' emotional growth, self-confidence, discipline, and social interaction. The methods used in this paper are observation and descriptive qualitative interviews with three resource persons, namely two physical education teachers, one class teacher at SDN 5 Imbanagara Raya. Data was collected through direct question and answer sessions that explore their experiences and views in observing changes in student behavior through PJOK activities. Based on the results of the interview, it was found that PJOK has an important role as a medium for student expression, especially for those who tend to be quiet or lack confidence. Physical activities and team games help students in forming self-confidence, discipline, and cooperation skills. In addition, collaboration between class teachers and physical education teachers is also an important key in adjusting teaching approaches that are responsive to students' emotional conditions. Thus, physical education contributes significantly to creating a learning environment that supports students' mental and emotional health.

Dextromethorphan (DXM) is a commonly used nonprescription cough suppressant that has gained field of science attention with its growing complex pharmacological effects and increased incidences of nonmedical use. This review is focused on pharmacokinetic, pharmacodynamics and CNS effects of DXM, especially on its action mechanism and the interaction with neural circuits and neurotransmitter systems. Although DXM has retained clinical utility as an antitussive, and has demonstrated potential as an off-label agent for neuropsychiatric disease, the recreational use of high doses can have harmful effects on the nervous system. At high doses DXM is capable of dissociation and hallucination similar to those induced by some opioids and NMDA antagonists, altering both mental status and cognition while being associated with neurotoxic effects. In this article, review and compare the similarities and differences between DXM and classic opioids in terms of their potential for abuse and their neurological effects. By case examples and existing epidemiological data, it also highlights the mounting abuse of DXM, most notably by children and young adults, posing a pressing public health challenge. Legislation on DXM is also described and differences in legislative response worldwide are highlighted. Finally, the article finishes by emphasizing the requirement for further studies involving other disciplines to detail the long-term neurological consequences of DXM abuse and to promote integrated public health interventions targeting education, prevention, and clinical treatment.

Generation Z consists of people born from 1995 to 2010. This generation has been familiar with technology since childhood. The purpose of this study is to determine the relationship between transformational leadership style and characteristics of generation Z employee members. This study uses a systematic literature review to identify and analyze the transformational leadership style on the characteristics of generation Z employee members, so that it can be used as a reference for future research and to help organizations understand better what they are doing. The results show that there is a match between transformational leadership style and the characteristics of generation z who value flexibility, collaboration, and innovation, often preferring workspaces that allow social interaction. Transformational leadership style is beneficial to improve the spirit, performance and participation of generation Z in public, business and social organizations.

Biochemical pathways are the complex pathways of chemical reactions vital to maintain cellular homeostasis, control metabolism and modulate responses to physiological stimuli. Recent developments in the omics technologies, gene editing tools, and systems biology have significantly deepened our understanding of these pathways, changing the scientific paradigm from linear reactions to complex and interrelated regulatory networks. This review examines the changing face of metabolic and signaling pathways including but not limited to glycolysis, TCA cycle, MAPK, PI3K/AKT and JAK/STAT and their role in health and disease. Particular attention is paid to pathway analysis innovations, including CRISPR/Cas9, single-cell and spatial transcriptomics, and computational modelling and their revolutionary effect on discovery of new drug targets and pathway specific therapeutics. In reviewing the most recent advances in cancer metabolism, immune signaling, and cross-pathway interactions, this paper emphasizes the translational promise of pathway-centric research for personalized medicine, especially in oncology, neurodegeneration, cardiovascular, and autoimmune diseases. The review attempts to bridge basic biochemical research with clinical applications, and provides a window into the manner in which pathway-based interventions are influencing the future of precision therapeutics.

Adolescents living in families where a parent has schizophrenia are at risk of experiencing significant psychological distress. This study aims to gain an in-depth understanding of the subjective experiences of a teenage boy in dealing with the psychological burden of having a mother with schizophrenia. The research employed a qualitative approach with a phenomenological method and utilized Interpretative Phenomenological Analysis (IPA) for data analysis. The participant in this study was a 16-year-old male adolescent who lives with his mother diagnosed with a chronic mental illness. The findings reveal that the subject experienced psychological burden in both objective forms, such as caregiving duties and domestic responsibilities, and subjective forms, including feelings of shame, anxiety, limited social interaction, and emotional conflict. Despite these challenges, the subject developed adaptive coping strategies through social engagement, sports activities, and support from peers and the surrounding environment. These findings highlight the psychological dynamics faced by adolescents in families affected by mental disorders and emphasize the importance of experience-based approaches in psychological intervention efforts.

This Community Service Program (PKM) was implemented in response to the high usage of social media among students, particularly Instagram, which often becomes a platform for cyberbullying. This phenomenon becomes increasingly complex when students come from diverse cultural backgrounds. Comments or posts considered normal in one culture may be perceived as offensive in another. A lack of cultural sensitivity often triggers digital conflict and bullying, which can negatively impact students' mental health. This PKM aims to improve students’ understanding of the dangers of cyberbullying and the importance of cross-cultural communication ethics. The program began with a pre-test to assess participants' initial knowledge, followed by an interactive seminar discussing the concepts of cyberbullying, digital ethics, and real-life case studies. Students then engaged in group discussions and simulations, where they analyzed problematic digital content and formulated empathetic, constructive responses. At the end of the activity, a post-test was conducted to evaluate the program’s effectiveness. The results showed a significant improvement in students’ awareness and attitudes. This program successfully encouraged students to be more thoughtful and responsible in their online interactions and to become change agents in creating a safer, more inclusive digital environment. The outcomes of this program include a scholarly publication, an educational video disseminated on social media, and quantitative data showing an increase in participants’ knowledge. Overall, this initiative contributes to strengthening multicultural digital literacy among today’s youth.

This Community Service Program (PKM) was implemented in response to the high usage of social media among students, particularly Instagram, which often becomes a platform for cyberbullying. This phenomenon becomes increasingly complex when students come from diverse cultural backgrounds. Comments or posts considered normal in one culture may be perceived as offensive in another. A lack of cultural sensitivity often triggers digital conflict and bullying, which can negatively impact students' mental health. This PKM aims to improve students’ understanding of the dangers of cyberbullying and the importance of cross-cultural communication ethics. The program began with a pre-test to assess participants' initial knowledge, followed by an interactive seminar discussing the concepts of cyberbullying, digital ethics, and real-life case studies. Students then engaged in group discussions and simulations, where they analyzed problematic digital content and formulated empathetic, constructive responses. At the end of the activity, a post-test was conducted to evaluate the program’s effectiveness. The results showed a significant improvement in students’ awareness and attitudes. This program successfully encouraged students to be more thoughtful and responsible in their online interactions and to become change agents in creating a safer, more inclusive digital environment. The outcomes of this program include a scholarly publication, an educational video disseminated on social media, and quantitative data showing an increase in participants’ knowledge. Overall, this initiative contributes to strengthening multicultural digital literacy among today’s youth.

Indonesia's biodiversity holds great potential for drug development, including through the use of traditional medicinal plants such as tapak liman (Elephantopus scaber L.), suruhan (Peperomia pellucida L. Kunth), and temu ireng (Curcuma aeruginosa Roxb.). These plants have been used in traditional medicine and are known to contain bioactive compounds with potential anticancer properties. Tapak liman contains compounds capable of inducing apoptosis in cancer cells. Suruhan is known to have cytotoxic and immunomodulatory effects, while temu ireng contains compounds with antioxidant and anticancer activity. This study aims to identify and quantify the bioactive compounds in these three plants using Gas Chromatography-Mass Spectrometry (GC-MS) and to explore their therapeutic potential in cancer treatment. The results of GC-MS analysis successfully identified six main compounds that have potential as anticancer agents, namely Phytol, Caryophyllene, Apiol, Germacrone, Germacrene B, and one additional compound. Temu ireng contains Germacrone, Germacrene B, and Caryophyllene, while suruhan contains Caryophyllene, Apiol, and Phytol. Meanwhile, tapak liman shows the presence of bioactive compounds that support cytotoxic activity. The focus of this study is on the interaction of bioactive compounds with the Bcl-2 protein, which plays a role in inhibiting apoptosis in cancer cells. Additionally, molecular analysis revealed that Germacrone, Germacrene B, Caryophyllene, and Apiol can also bind to the p53 protein, known as a guardian of the genome and a trigger for apoptosis. These findings suggest that the three plants have high potential as natural sources of anticancer agents. Further in vitro and in vivo studies are recommended to test the biological efficacy of these compounds in the context of cancer therapy, thereby bridging traditional knowledge with modern scientific approaches in the development of natural-based medications.

Background: Depression is the most common psychological disorder in the last years of an individual's life. Elderly depression has an impact including shortening life expectancy by worsening physical deterioration in the elderly, hindering the fulfillment of elderly development tasks, reducing the quality of life of the elderly, draining the emotions and finances of the affected person and their families and social support systems. Physiotherapist programs given to the elderly who are depressed include listening to English classical music and murottal. Purpose: For this community service activity, this community service activity aims to socialize the provision of English classical music therapy and murottal to reduce the level of depression in the elderly. : This community service activity uses the method of practical lectures and questions and answers. The lecture method was carried out by delivering material on depression and English music therapy. After that, the practice of listening to English and Murotal classical music, while the question and answer method was carried out by asking participants about the material that had been delivered. Results: The results of this community service activity were obtained that participants were able to understand and apply the material that had been delivered. Conclusion: Based on the community service activities that have been carried out, many of the participants enthusiastically received the entire series of events ranging from material presentations, the practice of listening to English classical music to question and answer interactions.