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Cardiac Troponin1 (cTn1) is a protein released into the bloodstream following cardiac damage and Brain Natriuretic Peptide (BNP) is a hormone released by the heart in response to ventricular stretch and pressure overload. This study aims to investigate the predictive role of cTn1 and BNP in preeclamptic pregnant women in the third trimester of pregnancy. Forty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. Blood samples was spun in a bucket centrifuge at 2500 RPM (rounds per minute) for 10 minutes after which plasma was collected and stored frozen in plain sample bottles and was analyzed for Cardiac Troponin 1(cTn1) and Brain Natriuretic Peptide (BNP) by fluorescence immunoassay. Data obtained from this study were analysed using Graph Pad Prism 9. Results generated were expressed as mean ± SEM and a P-value of ≤ 0.05 were considered statistically significant.  The present study showed that there was statistically significant increase in Brain Natriuretic Peptide (BNP) in preeclamptic women compared to normotensive pregnant women, indicating various underlying pathophysiological processes. These findings suggest the potential predictive roles of this cardiac marker in identifying and monitoring preeclampsia.

The potential of cardiac markers in predicting preeclampsia, such as Creatinine Kinase (CK) and Tyrosine Kinase 1 (TK1), has emerged as promising due to their involvement in the pathophysiology of this pregnancy complication. Preeclampsia is characterized by hypertension and organ dysfunction, and it can lead to significant maternal and fetal morbidity if not detected early. Early identification of preeclampsia is critical for preventing severe complications, and biomarkers like CK and TK1 can provide valuable insights. This study aimed to investigate the role of CK and TK1 as potential predictors of preeclampsia in the third trimester of pregnancy. Forty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. Participants were divided into two groups: twenty (20) normotensive pregnant women and twenty (20) preeclamptic pregnant women in their third trimester. Blood samples were collected and processed using a bucket centrifuge at 2500 RPM for 10 minutes, and plasma was stored frozen for further analysis. Tyrosine Kinase 1 was analyzed by fluorescence immunoassay, and Creatinine Kinase was measured using a spectrophotometric method. Data obtained were analyzed using GraphPad Prism 9, with results expressed as mean ± SEM. Statistical significance was set at a P-value of ≤ 0.05. The study found a statistically significant increase in the levels of both CK and TK1 in preeclamptic women compared to normotensive controls. These findings suggest that CK and TK1 could serve as predictive biomarkers for identifying and monitoring preeclampsia, aiding in early diagnosis and timely interventions

At present, little is known in Nigeria and globally about the association between stress and cortisol secretion in normotensive and preeclamptic pregnant women. Preeclampsia is a pregnancy complication that involves high blood pressure and organ damage, and it has been associated with various physiological alterations. This study aims to determine the comparative levels of cortisol, a stress marker, in preeclamptic pregnant women in the third trimester of pregnancy. Cortisol levels are known to fluctuate in response to stress, and altered levels may indicate an underlying pathophysiological process. Forty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. Blood samples were collected and spun in a bucket centrifuge at 2500 RPM (rounds per minute) for 10 minutes. The plasma was stored frozen in plain sample bottles and analyzed for cortisol levels using the enzyme-linked immunosorbent assay (ELISA) method. The data obtained were analyzed using GraphPad Prism 9 software. Results were expressed as mean ± SEM, and a P-value of ≤ 0.05 was considered statistically significant. The study found that cortisol levels significantly increased from 226.4 ± 36.53 nmol/L in normotensive women to 370.7 ± 36.47 nmol/L in preeclamptic women (p<0.05, <0.0081). This increase was statistically significant, suggesting that elevated cortisol levels in preeclamptic women may be linked to stress and potentially to oxidative stress cascade activation. These findings contribute to the understanding of stress-related physiological changes in preeclampsia and may offer insights for future diagnostic or therapeutic approaches.

The development of information and communication technology has brought significant changes in the world of education, encouraging educational institutions to adopt more innovative and relevant learning methods. This article discusses the implementation of Canva graphic design application training at Madrasah Aliyah Muhammadiyah Pekanbaru, which aims to improve the creativity and digital skills of grade XII IPA students. This activity was carried out through an interactive theoretical and practical approach, allowing students to not only learn about graphic design, but also apply that knowledge in real projects. The results of the training showed high enthusiasm from students, as well as significant improvements in their technical abilities and creativity. Evaluation of student design work indicated that the hands-on learning method was effective in improving digital literacy. These findings provide important insights into the potential of technology in creating a dynamic and innovative learning environment, and can be a reference for other community service programs aimed at improving digital competence in education.

Stunting is a serious health issue in developing countries that has long-term effects on children's growth, and it is important for parents to know about early detection of stunting so they can prevent it. The purpose of this research is to describe parents' general knowledge about early detection of stunting. This study uses a quantitative research type with a descriptive method and survey design. This study involves parents with toddlers, with a sample size of 293. The sampling technique used was consecutive sampling. Data were collected through a questionnaire that measures parents' knowledge about stunting and how stunting can be detected early. Data analysis was conducted using descriptive statistics to describe the characteristics of the respondents and their level of knowledge. The research results show that out of 293 respondents, the educational characteristics indicate that 58.4% are at the high school level. In terms of employment, 65.5% of respondents are housewives. Meanwhile, the analysis of the respondents' age characteristics shows that the median age is 32 years. In addition, the data regarding the respondents' knowledge shows that 82.3% have a high level of knowledge. As for the questionnaire, the question that was most frequently unanswered was question number 20, which discusses reading graphs on maternal and child health (MCH). There are efforts to improve mothers' knowledge about early detection of stunting because the research results still show that there are respondents with moderate knowledge.

PT Ansaf Inti Resources is a company engaged in coal mining using the open pit method. In the process of mining in open pit mines, haul roads are indispensable in the process of transporting overburden and play an important role in the mining production cycle. The purpose of the study is to determine the total resistance to overburden production of the LGMG CMT96 conveyance based on the haul road segment that has been determined from the overburden loading point to the disposal of the material, then a calculation is made based on the standard number of good total resistance to the actual haul road. After calculating all segments of the haul road, the results of plotting the total obstacle graph against the speed, travel time, and production of the haul. So every 1% increase in total resistance will reduce the speed of the conveyance 1.346 km / h, while every 1% increase in total resistance will reduce the travel time of the conveyance 0.0464 minutes. The production results of the CMT96 conveyance before the improvement of the total obstacle to the road surface amounted to 55 lcm and 49 lcm, while after the improvement of the total obstacle to the road surface there was an increase in the production of the conveyance of 68 lcm and 62 lcm. So every 1% increase in total resistance will reduce the production of conveyance by 4.7429 lcm.

The use of ECG patterns as predictors of preeclampsia offers a promising approach, as it is a widely available and cost-effective tool. Specific ECG patterns, including angle of deviation, QRS Complex (Right Ventricular Hypertrophy (RVH) , Left Ventricular Hypertrophy (LVH)), and T wave amplitudes as a potential tool for predicting preeclampsia. The aim of this study is to investigate the predictive role of angle of deviation, QRS Complex (Right Ventricular Hypertrophy (RVH) , Left Ventricular Hypertrophy (LVH)), and T wave amplitudes in preeclamptic pregnant women during the third trimester. Fourty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. These subjects consisted of  twenty (20) normotensive  and twenty (20) preeclamptic pregnant women in their  third trimester of pregnancy. After the subjects were  identified and recruited into the study, they were taken to the laboratory where their vital signs was taken and their ECG patterns recorded with ECG machine. Data obtained from this study were analysed using Graph Pad Prism 9. Results generated were expressed as mean ± SEM and a P-value of ≤ 0.05 were considered statistically significant. Results from this present study show no significant differences were observed in QRS complex angles related to right ventricular hypertrophy (RVH) between normotensive and preeclamptic pregnant women. Notably, there was a significant increase in QRS complex related to left ventricular hypertrophy (LVH) in preeclamptic pregnant women, indicating left ventricular remodeling's importance. Moreover, there was a significant increase in T wave amplitude, this suggests underlying myocardial electrical remodeling or dysfunction in preeclampsia, emphasizing the need for cardiovascular monitoring. The study underscores the multifactorial nature of cardiovascular changes in preeclampsia and highlights the potential of ECG parameters in aiding early detection.

Early detection and prediction of preeclampsia are crucial to prevent severe complications and ensure timely interventions, Specific ECG patterns, including PR segment, Q wave duration and amplitude, ST segment, U wave, and sinus rhythm were under study for their potential indicators of preeclampsia. This study aims to investigate the predictive role of these ECG patterns in preeclamptic pregnant women in the third trimester of pregnancy. Fourty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. These subjects consisted of  twenty (20) normotensive  and twenty (20) preeclamptic pregnant women in their  third trimester of pregnancy. After the subjects were  identified and recruited into the study, they were taken to the laboratory where their vital signs was taken and their ECG patterns recorded with ECG machine. Data obtained from this study were analysed using Graph Pad Prism 9. Results generated were expressed as mean ± SEM and a P-value of ≤ 0.05 were considered statistically significant. results from this present study show no significant differences were observed in the P-R segment, R-R interval, Q wave duration, Q wave amplitude The study underscores the multifactorial nature of cardiovascular changes in preeclampsia and highlights the potential of ECG parameters in aiding early detection, risk stratification, and management of the condition, despite  parameters showing no significant differences. However, PR Segment, Q Wave duration and amplitude, ST Segment , U wave and Sinus rhythm cannot be used to predict preeclampsia  

The ultimate goal of predicting preeclampsia that can enhance early detection and risk stratification in pregnant women, by leveraging the diagnostic potential of ECG patterns, we hope to improve maternal and fetal outcomes and contribute to the development of personalized care strategies for preeclamptic patients. Current diagnostic methods for preeclampsia rely primarily on routine blood pressure monitoring and proteinuria assessment, which have limited sensitivity and specificity. The aim of this study is to investigate the predictive role of P wave duration, amplitudes and morphology in preeclamptic pregnant women during the third trimester. Fourty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. These subjects consisted of  twenty (20) normotensive  and twenty (20) preeclamptic pregnant women in their  third trimester of pregnancy. After the subjects were  identified and recruited into the study, they were taken to the laboratory where their vital signs was taken and their ECG patterns recorded with ECG machine. Data obtained from this study were analysed using Graph Pad Prism 9. Results generated were expressed as mean ± SEM and a P-value of ≤ 0.05 were considered statistically significant. Results from this present study show statistically significant increases in P wave duration, amplitude and abnormal M pattern among preeclamptic compare to normotensive pregnant women, consistent with prior research, abnormal M pattern in P wave morphology is linked to atrial pathology in preeclampsia. The study underscores the multifactorial nature of cardiovascular changes in preeclampsia and highlights the potential of ECG parameters in aiding early detection, risk stratification, and management of the condition.

Push Up is a physical activity carried out by individuals that aims to strengthen the muscles of the body, namely the muscles of the arms, shoulders and chest. Designing an IOT-based detection and monitoring system with the aim of making it easier for tool users to know the number of repetitions and the number of calories used automatically. Detectoring with the help of four proximity sensors to detect motion when doing push-ups and monitoring using an android application made specifically for the device. The component used is NodeMCU ESP8266 as a microcontroller. The parameters displayed in the application include a column of push-up repetitions, a column for the number of calories used, and a graph of increasing push-up repetitions. The tool testing method was carried out 15 times for data collection with 20 push-up repetitions for each data collection. The results of the test, obtained an error percentage of 1.33%. So that this tool can help users to monitor the repetitions that have been done and find out the amount of calories used.

This training on making a 2025 desk calendar using the Canva application aims to improve the ability of MAS PAB 2 Helvetia students in making attractive and professional calendar designs. This training uses the Canva application as a graphic design tool that is easy to use and flexible. Participants will learn the basics of graphic design, how to use Canva, and techniques for creating effective calendar designs. It is hoped that the results of this training will improve participants' abilities in creating quality, attractive and efficient calendar designs using the Canva application.

Graphic design training using the Canva application aims to enhance the skills of MTs Al-Muttaqin students in creating visual designs, particularly posters with the theme "Environmental Awareness." This activity was conducted by the Community Service Program (KKN) team from Universitas Tidar on January 20, 2025, using the Asset Based Community Development (ABCD) method, which consists of five stages: discovery, dream, design, define, and destiny. The results of the training showed that students exhibited high enthusiasm and were able to understand basic design concepts, such as color, typography, and layout. Despite challenges such as limited internet access and devices, these obstacles were successfully addressed through intensive mentoring. This program is expected not only to improve students' digital literacy but also to provide opportunities for them to compete in the field of graphic design. In the future, this training can be expanded with additional materials to support broader educational digitalization.

Permasalahan dalam pengembangan media pembelajaran Aksara Lontara Bahasa Makassar untuk siswa sekolah dasar yang menggunakan animasi motion graphic berbasis multimedia adalah bahwa selama ini pembelajaran Aksara Lontara di sekolah masih mengandalkan buku dan belum tersedianya media pembelajaran interaktif yang mendukung proses belajar. Kondisi ini menyebabkan siswa mengalami kesulitan dalam mempelajari Aksara Lontara. Solusi atas permasalahan ini adalah pengembangan media pembelajaran Aksara Lontara dengan menggunakan Animasi Motion Graphic, yang diharapkan dapat memfasilitasi proses pembelajaran. Tujuan penelitian ini adalah mengembangkan dan mengimplementasikan media pembelajaran Aksara Lontara Bahasa Makassar dengan Animasi Motion Graphic berbasis multimedia di SDN Paccerakkang. Data diperoleh melalui penelitian lapangan, penelitian pustaka, dan wawancara. Metode yang digunakan adalah metode ADDIE, yang terdiri dari lima tahapan: Analisis, Perancangan, Pengembangan, Implementasi, dan Evaluasi. Hasil penelitian menunjukkan bahwa media pembelajaran yang dikembangkan mendapatkan persentase keberhasilan sebesar 76,66% dari pengujian alpha oleh ahli materi dan ahli budaya, yang termasuk dalam kategori layak. Sementara itu, persentase total dari pengujian beta yang dilakukan dengan memberikan kuesioner kepada siswa SDN Paccerakkang adalah 80,13%, juga termasuk dalam kategori layak.

C-reactive protein (CRP) and high-sensitivity C-reactive protein (hs-CRP) are general marker for inflammation and Arterial damage results from white blood cell invasion. This study aims to assess the level  of inflammatory markers C-Reactive Protein (CRP) and High-Sensitivity C-Reactive Protein (hs-CRP) in preeclamptic pregnant women in the third trimester of pregnancy. Fourty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. Blood samples was spun in a bucket centrifuge at 2500 RPM (rounds per minute) for 10 minutes after which plasma was collected and stored frozen in plain sample bottles and was analyzed for C-reactive protein (CRP) and high-sensitivity C-reactive protein (hs-CRP) levels by fluorescence immuno assay. Data obtained from this study were analysed using Graph Pad Prism 9. Results generated were expressed as mean ± SEM and a P-value of ≤ 0.05 were considered statistically significant.  The present study showed that there was statistically significant increase in the level of C-Reactive Protein (CRP) and High-Sensitivity C-Reactive Protein (hs-CRP) in preeclamptic women compared to normotensive pregnant women, indicating various underlying pathophysiological processes such as inflammation.

This final work aims to contribute to the preservation of local culture, as well as introducing graphic art as a means of telling stories and depicting community life, especially the activities of blacksmiths in Nagari Sungai Puar. Therefore, the author created a work entitled "graphic art: visualization of blacksmith activities in Nagari Sungai Puar using relief print techniques" and wanted to spread various elements in blacksmith activities, starting from the process of making tools and interactions between blacksmiths. The creation method used is the Halma Hawkins method through the stages of exploration, improvisation and formation. With this method, this work can later be visualized into a graphic art work using relief printing techniques. The final work product is ten works of graphic art measuring 55 x 40 cm which depict blacksmith activities in the Sungai Puar village. The works are entitled: Making a rod, Cutting iron, Burning furnace, Forging iron, Forming iron, Grinding a kite, Cooling a knife, Sharpening a knife, Skillful hands, Final stages.

UMKM are crucial to the country's economy and job creation, and in order for them to compete, inventive innovations must be made. Research, creativity, and observation can all help achieve this. Promotion is a means of targeting prospective customers with information about a product to pique their interest. Canva is an online design platform that provides a wide range of tools for creating graphics, infographics, banners, presentations, resumes, posters, brochures, booklets, and much more. One of Canva's numerous benefits is its wide variety of eye-catching designs. This gives UMKM the freedom to select and improve the originality of their marketing material. According to observations, the proprietors have designed the products' packaging and branding, yet they lack the.

Carcinoembryonic antigen (CEA) is a glycoprotein normally produced during fetal development, but presence of tissue damage and inflammation, its levels increase and this may be linked to  Carcinoembryonic antigen in the pathophysiology of preeclampsia. This study aims to assess the  level  of Carcinoembryonic antigen (CEA) in preeclamptic pregnant women in the third trimester of pregnancy. Forty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. After the subjects were  identified and recruited into the study, they were taken to the laboratory where their vital signs was taken and 10 milliliters (10 ml) of venous blood was drawn from consenting participants and placed in a lithium heparin sample bottles analyzed for Carcinoembryonic antigen (CEA) levels  by fluorescence immunoassay. Data obtained from this study were analysed using Graph Pad Prism 9. Results generated were expressed as mean ± SEM and a P-value of ≤ 0.05 were considered statistically significant. The present study showed that there was statistically significant increase in the level of Brain injury marker (CEA) was observed in preeclamptic women compared to normotensive pregnant women, indicating various underlying pathophysiological processes such as Brain injury in preeclampsia.

his community service program aims to empower youth in Tunjung Village through training in graphic design and branding using the Canva application. The training responds to the limited design skills among local youth, despite their basic knowledge of digital devices. In the digital era, the ability to produce visually appealing content is essential for promoting local products, supporting micro-enterprises, and enhancing community activities. The program was implemented using an Action Research (AR) approach, consisting of three main stages: preparation, implementation, and evaluation. The results showed a significant improvement in participants’ abilities to use Canva in designing various visual materials such as posters, banners, and logos. Despite several technical obstacles, such as limited device availability and unstable internet access, the training ran effectively. Final evaluations indicated positive responses from participants, who found the materials beneficial in enhancing their digital literacy and entrepreneurial potential. This initiative contributes to strengthening youth capacity in utilizing technology for productive and creative purposes.

This study aims to address the challenges and propose solutions for the Optimization of Blockchain-Based Cybersecurity Systems to Enhance Resilience Against Ransomware Attacks using a Systematic Literature Review (SLR) approach. Blockchain is increasingly recognized as a transformative technology in cybersecurity due to its decentralized structure, transparency, and robustness in securing data. Despite these advantages, its widespread adoption is hindered by several challenges, including scalability, interoperability, high energy consumption, and limited access to representative ransomware datasets. This research highlights that integrating blockchain with advanced technologies such as data analytics, machine learning, and Explainable AI (XAI) can significantly enhance its effectiveness in combating ransomware.The findings reveal that Graph Convolutional Neural Networks (GCN) enable real-time detection of ransomware patterns in network traffic with an accuracy of up to 95%. Furthermore, Layer-2 solutions like the Lightning Network and sharding effectively alleviate the load on main blockchains, thereby increasing transaction throughput. Efficient consensus mechanisms, including Proof of Stake (PoS) and Delegated Proof of Stake (DPoS), address energy consumption issues, making blockchain more adaptable to IoT and resource-constrained environments. These approaches have proven successful in enabling early detection, mitigation, and prevention of ransomware in IoT systems, cloud infrastructures, and smart grid networks. The implications of this study underscore the potential of blockchain as a critical component of proactive and adaptive cybersecurity systems. However, overcoming existing challenges requires further development of hybrid frameworks that integrate blockchain with data analytics and machine learning technologies. In addition, efforts should focus on standardizing global security protocols to enhance interoperability and creating robust, diverse ransomware datasets to support more accurate detection systems. Future research should also explore methods to minimize latency and improve blockchain efficiency in real-time cybersecurity applications.

The rapid development of multimedia technology has significantly advanced 3D animation techniques, enabling the production of high-quality visual content across industries such as film, gaming, architecture, and product visualization. Rendering, as the final stage of the 3D production pipeline, plays a crucial role in determining both visual realism and production efficiency. This study compares the performance of three rendering engines—Eevee, Cycles, and Radeon ProRender—by evaluating rendering speed, visual quality, and memory efficiency in Blender. The objective is to provide practical insights for designers and digital content creators in selecting the most suitable rendering engine based on project requirements. In this research, three identical 3D scenes were rendered using each of the three rendering engines under controlled experimental conditions. The comparison was conducted based on several parameters, including rendering time, output file size, shadow accuracy, lighting effects, and overall visual realism. Quantitative measurements were used to evaluate render speed and memory consumption, while qualitative analysis assessed differences in shadow detail, global illumination behavior, reflection accuracy, and material realism. The results indicate that Eevee outperforms the other engines in terms of rendering speed, making it highly suitable for real-time applications and projects requiring fast previews. Cycles produces the highest level of visual realism due to its physically based path-tracing algorithm, although it requires longer rendering time and higher computational resources. Meanwhile, Radeon ProRender demonstrates competitive performance, particularly in shadow quality and lighting effects, offering a balanced alternative between realism and efficiency. Based on the findings, Blender remains a flexible and effective platform. The choice of rendering engine should depend on whether speed, graphic quality, or memory optimization is prioritized.