Assessment of Inflammatory Markers (C - Reactive Protein and High Sensitivity C-Reactive Protein) in Preeclamptic Pregnant Women in the Third Trimester of Pregnancy

Edebiri O.E. ; Akpe C. I. ; Adewole A.S. ; Okike P.I. ; Ehigiamusoe E. A. ; Ohiwerei W.O. ; Omende K.
Journal of Health Sciences, Nursing and Nutrition 📅 2025 Vol 2, No 1 🔗 DOI: 10.70062/greenhealth.v2i1.145
Abstract
C-reactive protein (CRP) and high-sensitivity C-reactive protein (hs-CRP) are general marker for inflammation and Arterial damage results from white blood cell invasion. This study aims to assess the level  of inflammatory markers C-Reactive Protein (CRP) and High-Sensitivity C-Reactive Protein (hs-CRP) in preeclamptic pregnant women in the third trimester of pregnancy. Fourty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. Blood samples was spun in a bucket centrifuge at 2500 RPM (rounds per minute) for 10 minutes after which plasma was collected and stored frozen in plain sample bottles and was analyzed for C-reactive protein (CRP) and high-sensitivity C-reactive protein (hs-CRP) levels by fluorescence immuno assay. Data obtained from this study were analysed using Graph Pad Prism 9. Results generated were expressed as mean ± SEM and a P-value of ≤ 0.05 were considered statistically significant.  The present study showed that there was statistically significant increase in the level of C-Reactive Protein (CRP) and High-Sensitivity C-Reactive Protein (hs-CRP) in preeclamptic women compared to normotensive pregnant women, indicating various underlying pathophysiological processes such as inflammation.
Keywords
Cardiovascular Disease Screening Test; C-reactive Protein (CRP); High-Sensitivity C-reactive Protein (hs-CRP); Preeclampsia
How to Cite

Edebiri O.E., et al. (2025). Assessment of Inflammatory Markers (C - Reactive Protein and High Sensitivity C-Reactive Protein) in Preeclamptic Pregnant Women in the Third Trimester of Pregnancy. Journal of Health Sciences, Nursing and Nutrition, 2(1). https://doi.org/10.70062/greenhealth.v2i1.145

Edebiri O.E.; Akpe C. I.; Adewole A.S.; Okike P.I.; Ehigiamusoe E. A.; Ohiwerei W.O.; Omende K., "Assessment of Inflammatory Markers (C - Reactive Protein and High Sensitivity C-Reactive Protein) in Preeclamptic Pregnant Women in the Third Trimester of Pregnancy," Journal of Health Sciences, Nursing and Nutrition, vol. 2, no. 1, 2025.

Edebiri O.E.; Akpe C. I.; Adewole A.S.; Okike P.I.; Ehigiamusoe E. A.; Ohiwerei W.O.; Omende K.. "Assessment of Inflammatory Markers (C - Reactive Protein and High Sensitivity C-Reactive Protein) in Preeclamptic Pregnant Women in the Third Trimester of Pregnancy." Journal of Health Sciences, Nursing and Nutrition, vol. 2, no. 1, 2025.

Edebiri O.E.; Akpe C. I.; Adewole A.S.; Okike P.I.; Ehigiamusoe E. A.; Ohiwerei W.O.; Omende K.. "Assessment of Inflammatory Markers (C - Reactive Protein and High Sensitivity C-Reactive Protein) in Preeclamptic Pregnant Women in the Third Trimester of Pregnancy." Journal of Health Sciences, Nursing and Nutrition 2, no. 1 (2025).

Edebiri O.E., et al. (2025) 'Assessment of Inflammatory Markers (C - Reactive Protein and High Sensitivity C-Reactive Protein) in Preeclamptic Pregnant Women in the Third Trimester of Pregnancy', Journal of Health Sciences, Nursing and Nutrition, 2(1). doi: 10.70062/greenhealth.v2i1.145.

Edebiri O.E.; Akpe C. I.; Adewole A.S.; Okike P.I.; Ehigiamusoe E. A.; Ohiwerei W.O.; Omende K.. Assessment of Inflammatory Markers (C - Reactive Protein and High Sensitivity C-Reactive Protein) in Preeclamptic Pregnant Women in the Third Trimester of Pregnancy. Journal of Health Sciences, Nursing and Nutrition. 2025;2(1).

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