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Analytics

Khotimah, Khosnol; Arga Christian Sitohang

Perkembangan industri fashion muslim di Surabaya yang pesat diiringi dengan persaingan yang ketat antar pedagang. Penelitian ini bertujuan menganalisis pengaruh kualitas produk, harga, dan kreativitas terhadap pendapatan usaha pedagang fashion muslim di Pasar Atom Surabaya. Menggunakan pendekatan kuantitatif asosiatif, data primer diperoleh melalui kuesioner dari 50 responden yang dipilih dengan teknik purposive sampling. Analisis regresi linear berganda digunakan setelah uji validitas, reliabilitas, dan uji asumsi klasik. Hasil penelitian menunjukkan bahwa kualitas produk tidak berpengaruh signifikan terhadap pendapatan usaha (p=0,263), harga berpengaruh positif dan signifikan (p=0,000; B=0,565), dan kreativitas berpengaruh positif dan signifikan dengan koefisien tertinggi (p=0,000; B=0,633). Secara simultan ketiga variabel berpengaruh signifikan terhadap pendapatan usaha (F=61,629; p=0,000) dengan Adjusted R² sebesar 0,788. Temuan ini mengindikasikan bahwa dalam konteks pasar tradisional modern, kreativitas dan strategi harga lebih menentukan pendapatan dibandingkan kualitas produk. Implikasi manajerial bagi pedagang adalah memprioritaskan kreativitas dan fleksibilitas harga serta mempertahankan kualitas pada tingkat standar layak jual.

Bintang Aulia Nur’aini; Hari Saktiningsih

Jurnal Sains dan Kesehatan (JUSIKA) 2026 Universitas Muhamadiyah Manado

Chemical exposure during the dyeing process in the Textile industry has the potential to cause health problems, particularly allergic reactions mediated by Immunoglobulin E (IgE). Non-compliance with the use of Personal Protective Equipment (PPE) may increase the risk of chemical exposure through inhalation and skin contact, thereby triggering an allergic immune response characterized by elevated total IgE levels in the blood. This study aimed to determine the relationship between compliance with the use of Personal Protective Equipment (PPE) and total Immunoglobulin E (IgE) levels among Textile industry workers. This research was an analytic observational study with a cross-sectional design. The sample consisted of 15 Textile industry workers who met the inclusion and exclusion criteria, selected using purposive sampling technique. Data on PPE compliance were obtained through questionnaires and interviews, while total IgE levels were measured using the Electrochemiluminescence Immunoassay (ECLIA) method. The relationship analysis was conducted using Fisher’s Exact test. The results showed a significant relationship between PPE compliance and total IgE levels (p<0.05). It can be concluded that there is a significant association between compliance with the use of Personal Protective Equipment and total Immunoglobulin E (IgE) levels among Textile industry workers.

Aurelius Gelu; Ines Genoveva Hane; Maria Regina Moi Pea; Natalia Imelda Seran; Marylin S. Junias +1 more

Jurnal Sains dan Kesehatan (JUSIKA) 2026 Universitas Muhamadiyah Manado

Keamanan dan kesehatan di tempat kerja adalah salah satu hal penting dalam membentuk suasana kerja yang aman, terutama bagi pekerja bongkar muat (TKBM) yang menghadapi risiko kecelakaan kerja yang cukup besar. Pemakaian Alat Pelindung Diri (APD) yang memenuhi standar merupakan salah satu langkah untuk mencegah terjadinya kecelakaan kerja di area pelabuhan. Namun, hasil pengamatan di Pelabuhan Tenau menunjukkan masih ada pekerja yang mengenakan APD tidak sesuai standar SNI dan tidak menggunakan APD secara lengkap saat bertugas. Studi ini bertujuan untuk mengevaluasi dampak pendidikan penggunaan APD terhadap pengetahuan keselamatan kerja pada pekerja bongkar muat (TKBM) di Pelabuhan Tenau. Penelitian ini mengaplikasikan metode kuantitatif dengan desain pre-eksperimental yang menggunakan pendekatan one group pre-test dan post-test. Sampel penelitian terdiri dari 28 responden dengan alat penelitian berupa kuesioner yang berisi 10 pertanyaan. Hasil penelitian menunjukkan bahwa sebelum mendapatkan edukasi, rata-rata responden berhasil menjawab dengan benar 6 pertanyaan (60%) dan memberikan jawaban salah pada 4 pertanyaan (40%). Setelah mendapatkan edukasi, hasil post-test menunjukkan peningkatan pengetahuan di mana sebagian besar responden dapat menjawab dengan benar sebanyak 9 pertanyaan (90%) dan jawaban salah berkurang menjadi 1 pertanyaan (10%). Berdasarkan hasil studi, dapat disimpulkan bahwa pelatihan penggunaan APD berdampak pada peningkatan pengetahuan keselamatan kerja bagi tenaga kerja bongkar muat (TKBM). Sehingga, diperlukan pengawasan dan pendidikan secara berkala mengenai pemakaian APD yang memenuhi standar SNI untuk meningkatkan keselamatan kerja di area pelabuhan.  

Heriziana Hz; Shanti Rosalina

Jurnal Sains dan Kesehatan (JUSIKA) 2026 Universitas Muhamadiyah Manado

Work stress is a critical occupational health concern among midwives working at primary healthcare facilities. This cross-sectional study aimed to analyze factors associated with work stress among 30 midwives, including age, marital status, length of service, and dual-role conflict. Data were collected using structured questionnaires measuring work stress (9 valid items) and dual-role conflict (6 items), and analyzed through univariate, bivariate (Fisher's Exact Test and Chi-Square), and multivariate (binary logistic regression) analyses. Results showed that 43.3% of midwives experienced high work stress and 53.3% reported high dual-role conflict. Bivariate analysis revealed significant associations between work stress and marital status (p=0.009) and dual-role conflict (p=0.004), while age (p=0.633) and length of service (p=0.586) were not significant. Multivariate analysis identified dual-role conflict as the primary determinant of work stress (OR=15.762; 95% CI: 2.149–115.631; p=0.007). Healthcare facility management should develop gender-responsive policies and workplace stress intervention programs to reduce dual-role conflict and work stress among midwives.

Johan Juliawan Adhi; Matheus Mangentang; Stenly Reina Paparang

Coram Mundo : Jurnal Teologi dan Pendidikan Agama Kristen 2026 Sekolah Tinggi Teologi Injili Arastamar (SETIA) Ngabang

This article examines the influence of cell group (komsel) leadership, Christian lifestyle, and discipleship on the growth of the congregation at Christian Ministry Church (CMC) Jakarta. Employing a quantitative correlational design with 140 respondents, the study operationalizes three independent variables (X₁ = cell leadership; X₂ = lifestyle; X₃ = discipleship) against the dependent variable (Y = congregational growth). Pearson correlation analysis reveals significant correlations between cell leadership and lifestyle (r = .800, p < .01) and between cell leadership and discipleship (r = .591, p < .01), whereas direct correlations with Y were non-significant individually. Multiple regression yielded R = .752 and R² = .566, indicating that collectively the three predictors account for 56.6% of variance in congregational growth. These findings reinforce the argument that organic church growth is multidimensional and that the synergistic interaction of cell leadership, moral integrity, and discipleship constitutes a coherent growth ecosystem. Theological and pastoral implications are discussed within frameworks of contemporary missiology and cell ecclesiology.

Agnes Yuskila Elisabet Nenohai; Yublina Kasse

Coram Mundo : Jurnal Teologi dan Pendidikan Agama Kristen 2026 Sekolah Tinggi Teologi Injili Arastamar (SETIA) Ngabang

This article discusses the dynamics of Christian students’ spirituality in the digital era, characterized by the currents of globalization, information overload, and a culture of virtual communication that influence patterns of thinking, lifestyles, and character formation. The novelty of this study lies in its analysis of the direct relationship between the digital-global context and the process of students’ faith formation through an integrative theological–pedagogical perspective. This research aims to analyze the implications of digital globalization for the spirituality of Christian students and to formulate directions for faith formation that are relevant to the contemporary context. The method employed is a qualitative approach using a library research design through conceptual, theological, and pedagogical analysis of various relevant scholarly sources. The findings indicate that the digital era presents both opportunities and challenges for faith development, in which students experience a dynamic tension between the strengthening of spiritual insight and the potential value crisis resulting from exposure to global ideologies. In conclusion, contextual, reflective, and selective strategies of faith formation are required to ensure that the spirituality of Christian students remains firm, critical, and relevant amid the currents of digital globalization.

Anis Siti Qayyummah; Utary Rahayu; Andrey Pramudia; Dika Habib Permana; Miftahul Huda

Jurnal Miftahul Ilmi: Jurnal Pendidikan Agama Islam 2026 STIKes Ibnu Sina Ajibarang

This study aims to analyze the internalization of Islamic developmental psychology values through the Qur'an memorization (Tahfidz Al-Qur'an) program in shaping the character of middle adolescents aged 13–17 years in the digital era at Al Hayya Orphanage Foundation, Depok. Adolescence is a transitional stage characterized by significant physical, emotional, social, and spiritual changes. In the digital era, adolescents face various challenges, such as social media addiction, cyberbullying, declining social interaction, and moral degradation, all of which may affect character development. Therefore, strengthening character education based on Islamic values has become increasingly important. This research employed a qualitative approach using a case study method to gain an in-depth understanding of the phenomenon under investigation. Data were collected through observation, in-depth interviews, and documentation involving orphanage caregivers, Tahfidz instructors, and students at Al Hayya Orphanage Foundation, Depok. The findings indicate that the Tahfidz program plays a positive role in character formation through habituation, role modeling, spiritual guidance, and a supportive religious environment. From the cognitive perspective, students demonstrated improvements in discipline, concentration, responsibility, and self-regulation. Emotionally, they became more patient, better able to control their emotions, and experienced inner peace through intensive engagement with the Qur'an. Socially, the program fostered attitudes of mutual assistance, respect, empathy, and stronger social relationships among students.This study reveals that the Tahfidz program serves not only as a means of memorizing the Qur'an but also as an effective medium for internalizing the values of Islamic developmental psychology and fostering Qur'anic character among adolescents in facing the challenges of the digital era.  

Rahmah Diara; Mutiara Ramadhani Alfitriah; Muthliq Febrily Albachaj; Siti Nenk Lawati; Amelia Khoirunnisa +1 more

Jurnal Miftahul Ilmi: Jurnal Pendidikan Agama Islam 2026 STIKes Ibnu Sina Ajibarang

The purpose of this study was to analyze the implementation of Al-Qur’an and Hadith teaching at MAN 2 Karawang, including the challenges faced and approaches to resolving them. The method used was qualitative with a descriptive approach. Information was collected through interviews and documentation with the principal, Al-Qur’an and Hadith teachers, and eleventh-grade students. The research findings indicate that teaching is conducted in accordance with the madrasah curriculum, using a thematic and contextual approach that focuses on moral development and the application of Islamic values in daily life. Teachers use various methods, such as lectures, discussions, questions and answers, and hadith memorization. However, the teaching and learning process still faces several obstacles, such as a lack of infrastructure, including projectors, limited availability of textbooks, and unsupportive classroom conditions, which affect students’ concentration. Several solutions implemented include the gradual provision of facilities, the use of digital technology through students’ mobile phones and e-books, and the implementation of more interactive teaching methods to increase student motivation.

oktaviani, fifin; Oktaviani, Fifin; Muliana, Helda; Candra, Heldi

Perigel: Jurnal Penyuluhan Masyarakat Indonesia 2026 Universitas 17 Agustus 1945 Semarang

Substance and prescription drug misuse among adolescents continues to escalate and demands targeted preventive strategies within the school setting. This community service activity aimed to enhance students’ knowledge about the hazards of drug abuse through an interactive, school-based educational intervention. The program was conducted on 11 November 2026 at SMA Negeri 7 Kota Batam, involving fifty grade-X students as participants. A pre-experimental one-group pretest–posttest design was employed. The intervention combined interactive lectures, real-case illustrations, and two-way discussion, with knowledge measured using a content-validated questionnaire covering ten indicators. The mean score improved from 55.2 (pretest) to 86.3 (posttest), a gain of 31.1 points, while the proportion of correct answers across indicators rose from 48.6-62.9% to 80.0-91.4%. The largest gains appeared on items concerning rational drug use and the importance of professional health guidance, whereas the legal-consequence indicator improved more modestly. Interactive, contextually relevant education proves effective in elevating adolescent knowledge of drug abuse hazards, with stronger gains on experience-near content than on abstract regulatory aspects.

Aqiilah, Inge Najwa; Saptono, Ristu; Syaifuddin, Akhmad

Journal of Computing Theories and Applications 2026 Universitas Dian Nuswantoro

Document-level sentiment analysis assigns a single polarity label to an entire review, often obscuring opinion diversity within multi-sentence submissions. This limitation is particularly evident in reviews of multi-service platforms, where users frequently express heterogeneous opinions toward different aspects of the platform in the same review. To address this challenge, this study proposes a sentence-level sentiment analysis framework for Indonesian Gojek app reviews collected from the Google Play Store. The proposed framework introduces a two-stage segmentation strategy that combines punctuation-aware rules with conjunction-aware splitting based on coordinating and adversative conjunctions (e.g., tapi [but], padahal [even though]) to identify opinion boundaries and decompose mixed-sentiment reviews into independently classifiable sentence units. A total of 14,730 raw reviews collected between May and July 2025 were subjected to data cleaning and quality filtering, resulting in 7,187 valid reviews that were further segmented into 14,187 sentence-level instances. Each instance was manually annotated by three annotators using a four-class labeling scheme consisting of app-positive, app-negative, app-neutral, and service categories. Sentiment-level inter-annotator agreement, computed on the subset of instances unanimously categorized as app-related by all three annotators (n = 4,384), achieved substantial agreement (Fleiss'  = 0.636). Hyperparameter optimization was conducted using Optuna with the Tree-structured Parzen Estimator (TPE) sampler across four experimental scenarios. The best performance was achieved by IndoBERTweet under Stratified K-Fold evaluation, attaining an accuracy of 0.751 and a macro F1-score of 0.729, outperforming all IndoBERT configurations. The results demonstrate the effectiveness of domain-adaptive pre-training on informal Indonesian text and highlight the value of conjunction-aware segmentation for preserving fine-grained opinion structures in mixed-sentiment reviews. These findings suggest that domain-aligned language representations provide a practical and effective solution for sentence-level sentiment analysis of Indonesian app reviews.

Defnaldi; Siti Marfu’ah

Ulumul Quran merupakan salah satu cabang ilmu dalam studi Islam yang membahas segala sesuatu tentang Al-Qur’an, mulai dari proses turunnya wahyu, penulisan, pembacaan, penafsiran, hingga kandungan hukum yang terdapat di dalamnya. Kajian Ulumul Quran sangat penting karena membantu umat Islam memahami Al-Qur’an secara benar dan mendalam. Penelitian ini bertujuan untuk mengetahui pengertian Ulumul Quran, ruang lingkup kajiannya, serta peranannya dalam memahami kandungan Al-Qur’an. Metode yang digunakan dalam penelitian ini adalah metode studi pustaka dengan mengkaji berbagai sumber literatur yang relevan. Hasil penelitian menunjukkan bahwa Ulumul Quran memiliki kontribusi besar dalam membantu umat Islam memahami makna dan tujuan ayat-ayat Al-Qur’an secara tepat sehingga dapat diterapkan dalam kehidupan sehari-hari.

Adelia Putri Callysta; Feris Dzaky Ridwan Nafis; Anis Puji Rahayu

Jurnal Sains dan Kesehatan (JUSIKA) 2026 Universitas Muhamadiyah Manado

California papaya leaves (Carica papaya L.) are known to contain various active compounds that have the potential to stimulate appetite and boost metabolism, making them a promising candidate for development as a pharmaceutical formulation. This study aims to design a capsule formulation of California papaya leaf extract with appropriate excipients and to evaluate its ability to increase body weight through preclinical testing using a zebrafish (Danio rerio). The extract was obtained via maceration with 96% ethanol and formulated into capsules using the wet granulation method in four variations (F0–F3). Physical evaluations included organoleptic properties, flowability, angle of repose, loss on drying, disintegration time, weight uniformity, and stability testing using the cycling test method. The results indicated that all formulas met the physical requirements, with disintegration times of 3–4 minutes and loss on drying <15%. Formula F2 exhibited the most optimal physical characteristics; however, stability testing revealed a decline in physical properties after extreme temperature treatment. Efficacy tests showed a significant increase in zebrafish weight (p < 0.05), with F3 yielding the best results. A high survival rate (≥80%) suggests the formulation is relatively safe. In conclusion, California papaya leaf extract capsules demonstrate significant potential as an agent to promote weight gain.

Tahnia, Tia; Defrin, Defrin; Firdawati, Firdawati; Semiarty, Rima; Sriyanti, Roza +1 more

Jurnal Sains dan Kesehatan (JUSIKA) 2026 Universitas Muhamadiyah Manado

Preeclampsia is a pregnancy complication that significantly contributes to maternal and neonatal morbidity and mortality worldwide. Globally, it affects approximately 3–8% of pregnancies and causes more than 70,000 maternal deaths each year. In Indonesia, preeclampsia accounts for around 30% of the 4,151 maternal deaths reported in 2024. In Padang City, there were 254 cases in 2023 and 129 cases in 2024, with Puskesmas Bungus having the highest prevalence (7.2% and 3.77%). This study aimed to analyze the association between body mass index (BMI), history of hypertension, and history of preeclampsia with the incidence of preeclampsia among pregnant women at Puskesmas Bungus, Padang. This study used a quantitative case-control design involving 50 cases and 50 controls. Data were analyzed using chi-square and logistic regression tests. The results showed significant associations between obesity (p=0.031; OR=2.897), history of preeclampsia (p=0.006; OR=13.821), and history of hypertension (p=0.002; OR=17.216) with the incidence of preeclampsia. Multivariate analysis identified history of hypertension as the most dominant factor associated with preeclampsia. This study concludes that obesity, history of hypertension, and history of preeclampsia are significant risk factors for preeclampsia among pregnant women. Strengthening early detection and routine antenatal care for high-risk pregnancies is necessary to reduce maternal complications associated with preeclampsia.

Tiara Sandari M; Maison, Maison; Ilham Falani

Bhinneka: Jurnal Bintang Pendidikan dan Bahasa 2026 Universitas Palan

Misconceptions on the topic of waves are a systemic problem in high school physics learning that requires a comprehensive diagnostic instrument. Conventional diagnostic instruments up to the four-tier generation have limitations in revealing the conceptual structure behind students' thinking errors. This study aims to develop a five-tier multi-representation diagnostic instrument on the topic of waves using the 4D model (Define, Design, Develop, Disseminate). The main innovation of this instrument lies in the integration of multi-representations (verbal, pictures, graphics, mathematical) in Tier 1 and the addition of a paraphrase tier (Tier 5) that asks students to rewrite their understanding in their own words. The development process includes needs analysis, designing a grid of 16 questions, validation by two experts, and a limited trial on 34 grade XI students of SMAN 13 Kota Jambi. The results of expert validation showed an average percentage of 91.25% (Very Good) from both validators. Content validity was met with a percentage of False Positive (FP) of 6.80% and False Negative (FN) of 4.41%, both below the 10% threshold. Construct validity was confirmed through a significant Product Moment correlation (r = 0.342–0.348; sig. < 0.05) and factor analysis with six significant factors (eigenvalue > 1). The instrument's reliability was high, with a Cronbach's Alpha of 0.726. This instrument is expected to help physics teachers diagnose students' misconceptions more precisely and thoroughly on the topic of waves.

Aska, Aska; Wicaksana, Ervan Johan; Zurweni, Zurweni

Bhinneka: Jurnal Bintang Pendidikan dan Bahasa 2026 Universitas Palan

The keywords are required for computerization. Research and abstract title search made easy with these keywords. This study aims to determine the application of the entrepreneurship-based Project-Based Learning (PjBL) model to improve students' critical thinking and collaboration skills in Biology lessons at MAN 2 Tanjung Jabung Timur. This study used the Classroom Action Research (CAR) method, implemented in two cycles: Cycle I and Cycle II. Each cycle consisted of planning, implementation, observation, and reflection. Data collection techniques included observation, assessment, evaluation, reflection, and observation sheets for students' critical thinking and collaboration skills. The results showed that the implementation of the entrepreneurship-based PjBL model improved student learning outcomes, critical thinking skills, and collaboration. Assessment scores increased from 62 in Cycle I to 83 in Cycle II, representing a 33.87% increase. Evaluation scores increased from 73 to 93, representing a 27.40% increase, while reflection scores increased from 76 to 91, representing a 19.74% increase. Students' critical thinking skills also improved in the focus, reason, inference, situation, clarity, and overview indicators, which were dominated by categories 3 and 4 in Cycle II. Furthermore, students' collaborative skills improved across indicators of shared understanding, taking appropriate action, and team regulation. Based on the research results, it can be concluded that the implementation of the entrepreneurship-based Project-Based Learning (PjBL) model is effective in improving students' critical thinking and collaboration skills in Biology.

Ayu Febriasari; Jodion Siburian; Ali Sadikin

Bhinneka: Jurnal Bintang Pendidikan dan Bahasa 2026 Universitas Palan

This study aims to analyze the effect of the implementation of the Flipped Classroom model with a Deep Learning approach on the critical thinking and collaboration skills of Phase F XI students on the digestive system material. The study used a mixed methods with an embedded experimental design type. The research sample consisted of one experimental class that received Flipped Classroom learning with a Deep Learning approach and one control class that received Problem Based Learning (PBL) learning. Data on critical thinking skills were collected through essay tests, while collaboration skills were obtained through observation sheets. Quantitative data analysis used One-Way MANCOVA and qualitative analysis was carried out through data reduction, data presentation, and drawing conclusions assisted by NVivo. The results showed a simultaneous significant effect between the learning model on students' critical thinking and collaboration skills after controlling for initial abilities with a significance value of 0.002 (p<0.05). The average posttest critical thinking of the experimental group was 71.69 higher than the control group at 62.53. Meanwhile, the collaboration skills of both groups showed a relatively balanced increase. The ANCOVA results showed that the Flipped Classroom model with a Deep Learning approach significantly impacted critical thinking skills, but did not show a significant difference in collaboration skills. The research findings indicate that the integration of Flipped Classroom and Deep Learning is effective in improving students' critical thinking skills and supporting 21st-century learning.

M. Azka Khoirin; Esti Nur Janah

Jurnal Praba : Jurnal Rumpun Kesehatan Umum 2026 STIKES Columbia Asia Medan

Gastroesophageal Reflux Disease (GERD) merupakan gangguan saluran pencernaan di mana isi lambung berulang kali kembali ke kerongkongan, menyebabkan berbagai gejala dan komplikasi. Prevalensi GERD di Indonesia pada tahun 2023 dilaporkan sebesar 42,3% dengan 274.396 kasus. Data rekam medis RSUD Banyumas menunjukkan peningkatan kasus GERD dari 71 kasus (2023) menjadi 118 kasus (2024). Tujuan: Mendeskripsikan penerapan asuhan keperawatan pada pasien Nn. S dengan Gastroesophageal Reflux Disease (GERD) di Ruang Melati RSUD Banyumas. Metode: Studi kasus deskriptif dengan pendekatan proses asuhan keperawatan, dilakukan pada tanggal 27–28 Januari 2026 di Ruang Melati RSUD Banyumas melalui wawancara, observasi, pemeriksaan fisik, studi dokumentasi, dan studi literatur. Hasil: Diagnosis keperawatan yang muncul adalah nyeri akut berhubungan dengan agen pencedera fisiologis (D.0077), nausea berhubungan dengan gangguan pada esofagus (D.0076), dan defisit pengetahuan berhubungan dengan kurang terpapar informasi (D.0111). Intervensi yang dilakukan meliputi manajemen nyeri, manajemen mual, dan edukasi kesehatan. Kesimpulan: Setelah dilakukan implementasi keperawatan selama 2 hari, diagnosis nyeri akut dan nausea teratasi sebagian, sedangkan diagnosis defisit pengetahuan teratasi penuh. Discharge planning dilakukan dengan menganjurkan teknik relaksasi napas dalam, aromaterapi minyak kayu putih, serta modifikasi pola hidup sehat.

Muhammad Rizki Fadil; Fabian Gamal Sutrisno; Siti Fira Rahmawaty; Archie Fontana Iskandar

Jurnal Sains dan Kesehatan (JUSIKA) 2026 Universitas Muhamadiyah Manado

Circulating tumor DNA (ctDNA) has emerged as a promising liquid biopsy biomarker for real-time monitoring of tumor dynamics. In urothelial carcinoma (UC), effective monitoring of treatment response remains a clinical challenge due to the limitations of conventional imaging and invasive procedures. This systematic review aims to synthesize the existing evidence on the association between ctDNA dynamics and treatment response monitoring across various stages and therapeutic settings. A comprehensive systematic review was conducted. We included cohort studies, randomized controlled trials, and meta-analyses that evaluated ctDNA in UC patients undergoing treatment. Data were extracted on patient population, methodology, treatment, sampling strategy, clinical outcomes, and statistical associations. The review encompassed 80 studies. Baseline ctDNA positivity was strongly prognostic, associated with a 4- to 6-fold increased risk of recurrence or death (HR 4.23-6.56). Dynamic ctDNA clearances or significants reduction during treatment, were strongly associated with improved outcomes. Showing hazard ratios for adverse events as low as 0.10-0.31. ctDNA demonstrated time advantages of 53-90 days over radiographic detection. ctDNA is a potent tool for monitoring treatment response in urothelial carcinoma. It provides superior prognostic and offers a significant lead time for detecting treatment failure. Future research must focus on standardizing methodologies and validating ctDNA-guided therapeutic.

Siong Tji Djun; Tan Lili Wati; Sri Rezeki

Jurnal Pengabdian Kepada Masyarakat 2026 Sekolah Tinggi Pastoral Kateketik Santo Fransiskus Assisi

This community service study investigates a marketing training program implemented by theology students of STT Kadesi Bogor at the GPIA Sidoasri congregation in Sumbermanjing Wetan District, Malang Regency, East Java. The program targeted eighteen women members of the congregation to improve their economic capacity through the marketing of low-cost everyday clothing via three channels: door-to-door sales, a small storefront at the church, and online commerce through TikTok. The study applied a pre- test/post-test design evaluated using the Normalized Gain (N-Gain) method to measure changes in knowledge and skill across five indicators: marketing knowledge, selling skills, online media usage, basic financial recording, and entrepreneurial motivation. Results indicated a moderate-to-high N-Gain across all measured indicators, with an average N-Gain score of 0.656 (moderate category), and the highest individual gain in entrepreneurial motivation (0.76, high category). Sales data over the three-month period (January–March 2025) recorded a total profit of Rp1,967,500 across 345 garments sold, representing an income supplement of approximately 27–35% relative to participants' baseline household income for the most active participants. A marked sales decline in February and March was attributed to seasonal demand shifts ahead of Eid al-Fitr, as consumers redirected purchases toward formal Muslim attire. The program demonstrated that congregation-based economic empowerment rooted in a biblical theology of work, stewardship, and the dignity of labor can yield measurable and holistic socioeconomic outcomes for Christian women in rural communities.

Putri Selvi Febriyana; Siti Fatimah

Jurnal Praba : Jurnal Rumpun Kesehatan Umum 2026 STIKES Columbia Asia Medan

Background: Community nursing is a service process that is a combination of nursing and public health. Family nursing care is health services focused on the family where the entire process from assessment, diagnosis, planning, implementation to evaluation involves all family members both in healthy and sick conditions. The elderly are individuals in the age range of 60 years and above. Stroke is a disorder of brain function that appears suddenly accompanied by clinical signs both local and global in nature that last more than 24 hours caused by disruption of blood flow to the brain. Objective: To provide family nursing care to Tn. W with Neurological System Disorders: Stroke in Karangjati Village RT 02 RW 05 Tonjong District, Brebes Regency. Methods: This scientific paper is compiled using a descriptive narrative study approach following the stages of the nursing process including assessment, diagnosis, intervention, implementation, and evaluation. Data collection techniques include interviews, observation, physical examination, and documentation studies. Results: Nursing diagnoses that emerged were physical mobility impairment and knowledge deficit. Nursing interventions for physical mobility impairment included recognizing health problems and understanding stroke management, particularly related to mobilization through passive and active range of motion (ROM) exercises. For knowledge deficit, interventions included health education about stroke using educational media. Conclusion: After implementation over three days (December 27–29, 2025), the physical mobility impairment problem was partially resolved and knowledge deficit was resolved. It is expected that patients can increase their knowledge about health, particularly stroke disease.