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Carcinoembryonic antigen (CEA) is a glycoprotein normally produced during fetal development, but presence of tissue damage and inflammation, its levels increase and this may be linked to  Carcinoembryonic antigen in the pathophysiology of preeclampsia. This study aims to assess the  level  of Carcinoembryonic antigen (CEA) in preeclamptic pregnant women in the third trimester of pregnancy. Forty (40) consenting pregnant women were recruited from St. Philomina Catholic Hospital, Edo State, Nigeria. After the subjects were  identified and recruited into the study, they were taken to the laboratory where their vital signs was taken and 10 milliliters (10 ml) of venous blood was drawn from consenting participants and placed in a lithium heparin sample bottles analyzed for Carcinoembryonic antigen (CEA) levels  by fluorescence immunoassay. Data obtained from this study were analysed using Graph Pad Prism 9. Results generated were expressed as mean ± SEM and a P-value of ≤ 0.05 were considered statistically significant. The present study showed that there was statistically significant increase in the level of Brain injury marker (CEA) was observed in preeclamptic women compared to normotensive pregnant women, indicating various underlying pathophysiological processes such as Brain injury in preeclampsia.

Sterilization is a process that aims to remove all forms of microbial life, including bacteria, viruses, fungi, and spores, from an object or surface. This process is very important in various fields, such as medicine, laboratories, food industry, and pharmaceuticals, to prevent infection and contamination. This article was written through a literature review of articles originating from international and national journals. Data searches were carried out through scientific-based websites and databases, namely Google Scholar, Science Direct, and PubMed. The results show that of various sterilization methods such as autoclave, oven, ozone, filtration, steam, 70% alcohol, UV radiation and gamma rays, each has different effectiveness in killing microorganisms, and each method has advantages and disadvantages. . The conclusion of this article provides a comprehensive evaluation of the effectiveness of various sterilization methods used in laboratory and industrial contexts. Various techniques, such as autoclave, oven, ozone, filtration, steam, 70% alcohol, UV radiation and gamma rays.  

Modern cellular tissues have evolved into cell tensegrity structures, where cell strength and stability are established through supportive interactions. Tensegrity improves the efficiency of frequency spectrum use and signal quality in cellular networks. Research shows miRNAs play an important role in the regulation of gene expression in the immune system, providing new insights into the complexity of modern biological systems. Structural Design of Cellular Tissues involves computer simulation studies and laboratory experiments on cell tensegrity. Immune Regulation by MicroRNAs includes analysis of MiRNA gene expression and functionality using technologies such as microarrays and high-throughput sequencing. Data Integration includes identifying microRNA gene targets and understanding transcriptional regulation through methods such as reporter gene assays and Chromatin Immunoprecipitation to predict cellular responses in clinical scenarios. The complex interplay between cellular tensegratas mechanisms and immune regulation by microRNAs shows how widespread their interactions are in human biological systems. The cellular tensegratas structure helps improve intercellular communication, while immune regulation by microRNAs ensures the body's proper response to pathogens. Recent research on microRNAs has exposed their role in the development and function of mammalian immune cells. MiRNAs play an important role in the development and function of mammalian immune cells. The complex interactions between cellular tensile mechanisms and immune regulation by microRNAs demonstrate how structural and functional integration can improve the performance of human biological systems. Integration of these data provides a complete picture of the complexity of modern biological systems and their clinical implications in the diagnosis and treatment of immunological diseases.

With the increasing development of society, information is an important tool today. Information forces every person, both individuals and groups, both private and government, to calculate the information system that will be implemented in order to remain competitive in the era of globalization. In this case, the implementation of the right strategy allows every government agency to further improve services. In addition, the rapid advancement of information technology, but the lack of proper utilization. In general, the problems faced in the Information Technology Study Program Laboratory of Aisyiyah Pontianak Polytechnic are the suboptimal service of the inventory system where laboratory data is still manual so that the search time for equipment takes a long time. In instrumentation maintenance if it is still manual, it will be difficult to find out how many hours the equipment has been used and how many times it has been damaged. Along with the progress of Information Technology development, globalization is also becoming increasingly rapid. The specific objective of implementing the use of applications related to the theory of the concept of the course given to students. Analytical survey method with a Cross Sectional approach. The qualitative research design used is Phenomenological Research. The results of this study can improve the knowledge and skills of students, in improving knowledge in the field of Information Technology. Promoting the information technology study program at the Aisyiyah Pontianak Polytechnic.

The study entitled “Cream Formulation of Methanol Extract of Tapak Kuda (Ipomoea pes-caprae (L.) R. Br.) Leaves) As an anti-inflammatory in male white mice (Mus musculus)” using laboratory experimental methods with posttest control group design, data analysis using SPSS 25.0 with One Way ANOVA test and Duncan test. The percentage of extract yield obtained was 3.12%, phytochemical screening test showed the presence of secondary metabolite compounds alkaloids, terpenoids, flavonoids, saponins, tannins and steroids. Cream preparation of methanol extract of Tapak Kuda leaves at concentrations of 2.5%, 5% and 10% showed anti-inflammatory activity and the maximum dose to reduce edema diameter was 10% concentration with a percentage inhibition of 87.97%. Data analysis with One Way ANOVA test with a significance value ≤ 0.05 which indicates the presence of anti-inflammatory activity in Ipomoea pes-caprae tread leaf methanol extract cream.

Soil pollution is a global problem with anthropological and natural sources. Pesticides are chemical compounds used to eradicate pests. Pesticides are chemical or biological agents that can weaken, paralyze, and kill pests. According to a report by FAO (2021), global pesticide use reaches more than 4 million tons per year, with Asia accounting for nearly 50% of total consumption. In Indonesia, data from the Ministry of Agriculture (2022) shows that pesticide use increased by 15% in the last decade. Unfortunately, the intensive and uncontrolled use of pesticides has triggered the accumulation of harmful residues in the soil, creating a serious threat to soil, environmental, and human health. The purpose of this study was to determine how the utilization of microbiology in the bioremediation of agricultural soil polluted with pesticides. The method in this journal article uses a library study (library research), namely a method with data collection by understanding and studying theories from various literatures related to the research. The results show that soil bioremediation to reduce pesticides in agricultural soils can be done by utilizing specific or local microorganisms (bacteria and fungi), or enzymatic degradation. Although in laboratory scale, many findings on soil bioremediation are available in the literature, only few data on real scale activities can be found.    

This study discusses the Optimization of the Use of Islamic Religious Education Laboratories in the Practice of Student Worship at State Junior High Schools in Pangkajene District, Pangkep Regency. The main problem is how the Islamic Religious Education Laboratory can be optimized as a facility and infrastructure that supports the development and progress of Islamic Religious Education. The author uses a research approach with qualitative methods in data collection, as well as testing and analyzing data qualitatively. The research paradigm is constructivism; data sources are Principals, PAI Teachers, Students (primary data) and documents related to the management of the PAI Laboratory (secondary data); The research instrument is the researcher himself and is assisted through data collection tools, namely observation guidesheets, interview guidelines and document study guidelines; Data collection techniques are participation observation, in-depth interviews, and documentation; and testing the validity of the research results applying source triangulation and triangulation techniques. The research was carried out in four State Junior High Schools in Pangkajene District, Pangkep Regency. The results of the study showed that 1) The condition of PAI laboratories in the schools studied varied in terms of availability and quality of facilities. All schools have PAI laboratories, but there are gaps in infrastructure and equipment due to differences in budget allocation. 2) Laboratory use of PAI showed variation in intensity and effectiveness. Some schools have integrated the use of laboratories into the curriculum, while others still face challenges in optimization. 3) The practice of students' worship varies in the level of consistency and understanding. The majority of students have awareness of the importance of worship, but the level of practice varies. 4) Factors that affect the use of PAI laboratories include the availability of infrastructure, teacher competence, budget allocation, school management, student motivation, and education policies. This study recommends increasing budgets, developing teacher competencies, integrating curriculum, collaboration between schools, utilizing technology, and periodic evaluations to optimize the use of PAI laboratories and improve students' practice of worship.

Bagelen bread is a processed dry bread product, processed by re-baking the finished bread to become dry bread. This study aims to determine the right  formulation of canna  starch substitution  for wheat flour in making bagelen dry bread, and to examine the effect of canna starch substitution on the physical properties, chemical properties and sensory properties of bagelen. The study was conducted at the Laboratory of Food and Agricultural Product Processing, Faculty of Agricultural Technology, University of 17 August 1945 Semarang. The research design used a completely randomized design (CRD) with 4 treatments and each treatment was repeated 3 times. Data were analyzed using Anova (Analysis of Variance) at a 95% confidence level. If significantly different, Duncan's Multiple Range Test (DMRT) will be carried out. The results of the analysis of physical hardness properties showed significant differences and the results of the color analysis (L a * b *) showed no significant differences. The results of the chemical properties analysis showed that there was no significant difference in water, ash and fat content, but there was a significant difference in protein and carbohydrate content in bagelen bread. The protein content of bagelen bread will decrease in line with the increasing portion of ganyong starch. Meanwhile, carbohydrate levels will increase as the number of canna starch substitutes increases. The results of the sensory properties analysis of color, aroma, taste and texture of bagelen bread showed significant differences. Substitution of canna starch up to 40% did not affect the level of preference for the attributes of taste, color, and aroma of bagelen bread, but the texture of the substitution with canna starch was less preferred.

This study aims to identify the problems faced by students in implementing learning. This study used a quantitative approach with a survey method, involving 30 students from two high schools in Yogyakarta. Data were collected through questionnaires about students' learning difficulties, interests, and needs for learning media. The results showed that 96% of the students considered chemistry as a difficult subject to understand because of the abstract nature of the material. As many as 64% of the students felt bored due to the uninteresting presentation of the material, while 72% of the students indicated the need for varied learning methods and interactive learning media to facilitate understanding. The results of the study showed that an innovation was needed to support chemistry learning activities to make learning more active and enjoyable so that it does not lead to student boredom. The developed virtual laboratory media provides flexible, safe and economical simulation of chemical experiments. This application is designed to be accessible without an internet connection using an Android device, allowing students to learn anytime and anywhere. The use of this virtual lab is expected to increase students' motivation, understanding of concepts, and learning experience.

Seed plants (Spermatophyta) are a group of plants with a very high level of diversity and are widely distributed throughout the world. This group of plants is known as higher plants or Phanerogamae, namely plants that have seeds and reproduce sexually. Spermatophyta can be divided into two main groups, namely Gymnospermae or plants that have characteristics of open seeds and Angiospermae or plants that have characteristics of closed seeds. Research on the structure of internal reproductive organs of seed plants was carried out at the Instructional Laboratory 1 on Campus I UIN SGD Bandung, Cipadung Village, Cibiru District, Bandung City, West Java Province. Qualitative methods were used in this study by conducting direct observations on the objects being observed. This study aims to see and observe how the reproductive structure is in seed plants. Based on data from observations made on paper flowers (Bougainvillea), the flower has no petals, 3 crowns attached to 27 stamens, and 4 pistils with the flower formula K0 [C3 A27] G4. Meanwhile, in the study of lilies (Crinum jagus) have 5 petals, 6 crowns attached to 6 stamens, and 1 pistil with a flower formula of K5 [C6 A6 ] G1.

This study aims to analyze the quality of service in the Culinary Arts Practical Laboratory at SMK Ibu Pertiwi 1 using the Service Quality (Servqual) method. Service quality is an important element in supporting the success of the education process, especially in the Culinary Arts expertise program that requires laboratory facilities as a means of practical learning. The Servqual method is used to evaluate five main dimensions, namely tangibles, reliability, responsiveness, assurance, and empathy.This study was conducted by collecting data through questionnaires distributed to students as users of laboratory services. Data analysis used a comparison between students' expectations of ideal service quality and their perceptions of the services received. The results of the study showed a gap in several dimensions of service quality, especially in the tangibles dimension which includes the completeness and condition of laboratory facilities. In addition, the responsiveness and reliability dimensions are also of concern because students feel that the response to complaints and service consistency are not optimal.From the results of the study, it can be concluded that the quality of laboratory services needs to be improved to meet student expectations. Recommendations for improvement include improving physical facilities, training for laboratory staff to improve responsiveness and reliability, and strengthening security assurance in the practical learning process. This study contributes to school management in creating a more effective and quality learning environment.

Previous studies have shown that red ginger has the potential to treat PCOS because it has been proven to be able to reduce serum FSH, LH and estradiol and testosterone, inhibit the cyclooxygenase pathway, change the pituitary axis, inhibit lipoxygenase expression in various animal studies. The purpose of this study is to prove the potential of red ginger extract as a regulator of anti-androgenic, ovulation, estrogenic activity and reduce insulin resistance. The research design used was for experimental research using a post-test-only control group design. And for the analysis of the potential bioactivity of red ginger extract as an immunomodulatory agent computationally (Insilico). Animal care was carried out in the Pharmacology and Biomedicine Laboratory and has received approval from the Ethics Committee. The sample used was a female Wistar rat on the 56th day of the experiment (after modeling). All treatments were given orally for 28 times. Independent variable = Red ginger extract. Dependent variable = Dependent variables are 1. Hormones: Testosterone, LH, FSH 2. ovarian inflammation activation (PPARγ activation and anti-inflammatory cytokines IL-4 and ROS, NFKB, TNF a. 3. Insulin resistance (insulin, glucose, HOMA IR) and 4 Lipid profile (TG, HDL, LDL, cholesterol). Control variables are: 1) Gender; 2) Age; 3) Strain; 4) Food and beverage intake; 5) Maintenance and care. Quantitative and qualitative research data. using parametric tests, namely One-Way ANOVA after meeting the requirements for normal data distribution and the same data variance. The One-Way ANOVA statistical test is continued with the Tuckey test to determine the differences in each group.

The purpose of this research is to examine and analyze the validity of scientific crime investigation as evidence in the process of proving murder cases and what are the advantages and disadvantages of using the scientific crime investigation method in crime scene processing carried out by forensic laboratories. Then the method used in this research is the normative legal research method. The results of the study show that the scientific crime investigation method, which is expressed in concrete form through forensic laboratory examinations and information from police forensic experts, is the central point. In connecting the relationship between the perpetrator, victim and evidence with the crime scene, the construction of evidence for a criminal act becomes stronger and can give confidence to the judge in deciding a case fairly and in accordance with the actual facts. In the case of the crime of murder with poison, the statements of the witnesses and the statements of the two defendants were linked and interconnected with each other after the scientific crime investigation method was applied; The advantages and disadvantages of using scientific crime investigation methods in crime scene processing carried out by forensic laboratories include. The advantages and disadvantages of using scientific crime investigation methods in crime scene processing carried out by forensic laboratories include: (1). The advantage of implementing scientific crime investigation is that uncovering cases using old methods full of violence, intervention, etc. has been abandoned. (2) Fast, precise and accurate inspection supported by special tools that have been internationally standardized, (3) Minimizing errors made before SCI implementation (manual patterns replaced with digital patterns). Meanwhile, the weaknesses are: Internal side of the SatKer (Work Unit): the number of human resources who supervise and understand the use of Special Tools (Alsus) is limited, the special equipment, both primary and secondary, is expensive. If we look at the human resources that this country has, it should be enough to assist the Forensic Laboratory team in supervision and are people who understand the special tools that support the performance of the Forensic Laboratory. Apart from that, the government should be more respectful of the procurement of these special tools, even though not everyone has to always use these special tools. However, these tools are very useful for the smooth running of investigations and/or investigations. Because the resulting examination data is much more detailed and accurate.

This Electronic Medical Record is a digital version of a medical record, the same as a paper-based manual medical record, this electronic medical record also contains information regarding health history, diagnoses, laboratory results, examination notes, medications given, medical procedures, and other data. relevant to the patient's health condition. It is hoped that the implementation of Electronic Medical Records can increase the efficiency of BPJS claims and improve the quality of service. Therefore, this study aims to analyze the use of RME using the Delone and Mclean method. The Delone and Mclean method is an information system quality evaluation framework that includes six dimensions, namely information system quality, information quality, service quality, use quality, user satisfaction, and user impact. In this study, we apply this method to analyze the quality of RME management. This research uses a quantitative approach by collecting data through questionnaires distributed to RME users in hospitals. The questionnaire measures user perceptions of information system quality, information quality, service quality, use quality, user satisfaction, and impact of using RME. The results of this research are expected to provide better insight into the use of RME in the context of work efficiency. The findings of this research will provide input for RME developers to improve the quality of information systems, the quality of information, and the quality of services provided to users. Apart from that, this research also contributes to theory and research in the field of information systems by applying the Delone and Mclean method in the context of RME management.

Worms are an infectious disease caused by parasites in the form of worms. According to data from the Papua Province Health Service in 2011, the number of worm cases was 528.8 per 1,000 population, while in the Jayapura City Health Service the number of worm cases in 2011 was 2.48 per 1,000 population. According to data from the Abe Pantai Community Health Center, the prevalence of worms in 2012 was 3.21 per 1,000 population. The prevalence in Hedam Community Health Center, Waena Community Health Center and Kotaraja Community Health Center in 2012 was 1.94 per 1,000 population, 1.25 per 1,000 population, 0.94 per 1,000 population, respectively. Vegetables that are eaten directly are at risk of being contaminated by various types of parasites during planting, harvesting and marketing and have the potential for transmission of infection to humans. This study aims to determine whether or not there is contamination with STH (Soil transmitted helminth) worm eggs contained in fresh vegetables from roadside tent stalls in Abepura District. The type of research used is descriptive research using a laboratory approach. The research sample was 20 samples of roadside tent stall traders in Abepura District taken using Random Sampling Technique. The method for examining worm eggs uses the Sedimentation method. The results of identification of worm eggs in fresh vegetables sold by roadside stall vendors in Abepura District showed that there was worm egg contamination found in 20 samples of fresh vegetables, with 8 samples contaminated or 40% and 12 samples or 60% not contaminated with worm eggs Soil transmitted helminth. The types of Soil Transmitted Helminth worm egg species found were Ascaris lumbricoides (35%), Trichuris trichiura (30%) and Hookworm (30%)

Hermina Hospital is one of the organizations that is a learning organization under the auspices of PT. Medikaloka Hermina Group. Hermina Hospital carries out Key Performance Indicators (KPI) to evaluate employees who work at Hermina Hospital. What is assessed from the KPI includes competency, performance, human resource development that is assessed, namely employee dropout and employee engagement with the company. Based on the results of interviews with the HRD department at Hermina Hospital, hospital employees with satisfaction, performance and strong attachment to the company were 73% of medical employees and 27% of non-medical employees. The data corresponds to the KPI values ​​for the period December 2022-May 2023 from each KPI unit that is declared good is with a minimum value of 6 (six) or more, along with data with a KPI value of less than 6, namely Directors, Jangmed, HRD, Finance, Quality staff and Accreditation, General Support and JKN, CSSU, Marketing while the KPI scores in the good category are Nursing, Yanmed, Laboratory units. The aim of this research is to analyze the influence of learning organizations on the performance of non-medical staff with job satisfaction, competence and employee engagement at Hermina Lampung Hospital. This research uses a questionnaire from the development of a previous research questionnaire. The questionnaire was collected using Google forms. This research uses a quantitative research method using a perception survey method to collect data from the population. This perception survey was conducted by distributing a list of questions to respondents. The survey conducted in this research was a cross-sectional survey. Apart from that, this research also used a quantitative descriptive approach using a total sampling that met the inclusion criteria of 58 respondents. Analysis using the path analysis method. The research results from data analysis showed that there was an influence between learning organization on performance, there was an influence of learning organization on job satisfaction, there was an influence of learning organization on competence, there was an influence of job satisfaction on performance, there was an influence of employee engagement on performance, while competency had no influence on performance.

Dengue Hemorrhagic Fever (DHF) is a disease caused by the Dengue virus and has a significant impact on public health, especially in tropical areas. Early diagnosis and prediction of DHF risk are essential to prevent complications and improve medical care. This study aims to develop a DHF risk prediction model using the Decision Tree method based on clinical symptoms and laboratory data. The data used include symptoms such as fever, joint pain, rash, and laboratory results such as platelet count and hematocrit. The Decision Tree model was chosen because of its ability to handle data with various variables and provide easy-to-understand interpretations. The research data were taken from patients diagnosed with DHF in several hospitals during a certain period. The dataset was then analyzed to find relevant patterns that could predict a high risk of DHF. The model training and testing process was carried out using cross-validation techniques to ensure prediction accuracy. The results showed that the Decision Tree model had an accuracy rate of 96.95% and consistent results from cross-validation which produced an average accuracy of 92.8%,, with good sensitivity and specificity in predicting DHF risk based on a combination of clinical symptoms and laboratory data. Factors such as low platelet count and fever symptoms lasting more than three days were found to be significant predictive variables. In conclusion, this Decision Tree model has the potential to be used as a tool in early prediction of DHF risk, which can help medical personnel in clinical decision making and patient management. Further development can be done by adding other variables such as epidemiological data to improve model performance.

Dengue Hemorrhagic Fever (DHF) is a disease caused by the Dengue virus and has a significant impact on public health, especially in tropical areas. Early diagnosis and prediction of DHF risk are essential to prevent complications and improve medical care. This study aims to develop a DHF risk prediction model using the Decision Tree method based on clinical symptoms and laboratory data. The data used include symptoms such as fever, joint pain, rash, and laboratory results such as platelet count and hematocrit. The Decision Tree model was chosen because of its ability to handle data with various variables and provide easy-to-understand interpretations. The research data were taken from patients diagnosed with DHF in several hospitals during a certain period. The dataset was then analyzed to find relevant patterns that could predict a high risk of DHF. The model training and testing process was carried out using cross-validation techniques to ensure prediction accuracy. The results showed that the Decision Tree model had an accuracy rate of 96.95% and consistent results from cross-validation which produced an average accuracy of 92.8%,, with good sensitivity and specificity in predicting DHF risk based on a combination of clinical symptoms and laboratory data. Factors such as low platelet count and fever symptoms lasting more than three days were found to be significant predictive variables. In conclusion, this Decision Tree model has the potential to be used as a tool in early prediction of DHF risk, which can help medical personnel in clinical decision making and patient management. Further development can be done by adding other variables such as epidemiological data to improve model performance.

This Industrial Internship (Prakerin) was conducted at PT. Perkebunan Nusantara IV Regional II, Plantation Unit, and Adolina Palm Oil Mill (PKS). It focused on analyzing the effect of crude palm oil (CPO) thickness in the Continuous Settling Tank (CST) on CPO impurity levels. The issue raised was the persistent variation in impurity levels in CPO, which is suspected to be influenced by the thickness of the oil layer during the collection process. This study aimed to determine the relationship between CPO thickness in the CST and the resulting impurity levels. The method used was CPO sampling at several oil thicknesses (33–46 cm), followed by laboratory impurity analysis using Gooch Crucible Filter filtration and gravimetric calculations. Data were obtained during the period July 4–11, 2025. The results showed that at a thickness of 45–46 cm, the lowest impurity content was 0.01%, while at a thickness of 33 cm, the highest impurity content was 0.04%. At a thickness of 35 cm, the impurity content was 0.03%, and at a thickness of 40 cm, it was 0.02%. This indicates an inverse relationship between CPO layer thickness and impurity content, where the thicker the oil layer, the lower the impurity content. Therefore, it can be concluded that maintaining a minimum oil thickness in the CST tank of ±40 cm is a crucial step in maintaining CPO quality and ensuring it meets industry standards.

One of the major causes of death in the globe is cancer. According to estimates, the number of people affected by cancer worldwide will continue to rise, reaching 21.4 million new cases and 13.2 million deaths by 2030.This study was carried out in the Sudanese state of East Darfur and it is a retrospective in nature. Clinical and Public Health Laboratory provided results, were collected, gathered then analyzed. The Statistical Package for Social Science (SPSS) version 25 was used evaluate demographic data and tumor cases. show that 87.3% of patients who were affected by were females, while only 12.7% of patients were males show that 15.87% of patients whom affected were 33 years old, followed by 9.52% their age were 34 and 45 years old endometritis accounted for (19.05% ) of the abnormalities that affected the patients, followed by ovaries (14.29%), endometrial polyps (12.70%), Breast masses (7.94%), chronic endometritis, prostatic hyperplasia The data on the present status of the most common benign and malignant tumors in Sudan and the neighboring areas is scarce. There is a complex interaction between the impact of infectious agents, genetics and environmental risk factors on the risk of development of most of these tumors.