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Breast cancer represents a significant public health challenge in Indonesia, accounting for the highest incidence with 68,858 new cases annually (16.6%). This study aimed to evaluate the therapeutic potential of bioactive compounds derived from Zingiber officinale (ginger) as anticancer agents, specifically against estrogen receptor-positive (ER+) breast cancer through the inhibition of estrogen receptor alpha (ERα). Utilizing molecular docking simulations, six active ginger compounds were assessed against the 3ERT receptor. Dihydrocurcumin and tetrahydrocurcumin were identified as the most promising candidates, exhibiting superior binding affinities of -8.091 kcal/mol and -7.565 kcal/mol, respectively, indicative of stable ligand-receptor interactions. A complementary in silico pharmacokinetic evaluation using pkCSM for zingerone, dihydrocurcumin, and tetrahydrocurcumin revealed favorable ADMET profiles, characterized by good intestinal absorption, adequate tissue distribution, low toxicity, and non-mutagenicity. Collectively, these findings underscore the significant potential of these ginger-derived compounds as promising lead candidates for the development of natural product-based breast cancer therapies

This research explores the meaning of leadership in employee experiences at Ayam Uleg Cak Abit outlets in Malang City using a transcendental phenomenological approach. In the context of culinary organizations operating 24 hours without formal managerial structures, leadership is understood not merely as a structural position but as relational experiences shaping daily work life. This study involves six participants (two leaders and four employees) selected through purposive sampling, with data collected through in-depth interviews, non-participatory observations, and documentation. Data analysis follows Moustakas' (1994) four stages: epoche, phenomenological reduction, imaginative variation, and synthesis of meanings and essences. Findings reveal that employees perceive meaningful leadership through leader's direct presence, involvement in operational work, emotional support during high-pressure situations, and creating work environments valuing each employee's contribution. Leadership essence emerges through authentic relationships, consistent exemplary behavior, and sincere care in daily interactions rather than formal authority or hierarchical position. This research contributes to leadership theory by providing phenomenological perspectives and offers practical implications for developing more humanistic leadership practices in informal organizations. The study concludes that meaningful leadership in culinary outlets is built through trust, open communication, and ability to build significant relationships with employees.

Limited access to adequate housing remains a major challenge for low-income households in Indonesia, including in Banyumas Regency. The subsidized housing program has been implemented as a public policy instrument to improve housing affordability while enhancing social and economic welfare. This study aims to analyze the role of subsidized housing in improving housing access and the economic conditions of low-income communities in Banyumas Regency. The research adopts a qualitative approach using a documentation study method by collecting and analyzing policy documents, official government reports, scholarly journal articles, and relevant publications related to subsidized housing and the socio-economic conditions of low-income households. Data analysis was conducted through content analysis to interpret the role of subsidized housing based on indicators of housing affordability and household economic impacts. The findings indicate that subsidized housing significantly reduces the housing cost burden of low-income households from levels exceeding the affordability threshold to a more economically manageable range. The reduction in housing expenditure contributes positively to household economic stability by allowing savings and reallocation of income toward productive needs such as education, healthcare, and financial security. However, the effectiveness of subsidized housing in improving economic outcomes is still influenced by location and accessibility of housing areas. This study concludes that subsidized housing plays a crucial role in expanding housing access and improving the economic conditions of low-income communities, while requiring integrated and sustainable policy support to maximize its long-term benefits.

Waktu tunggu pelayanan resep obat merupakan salah satu hal penting dalam pelayanan kefarmasian di puskesmas. Waktu menunggu dapat mempengaruhi kepuasan pasien ketika mendapatkan pelayanan, sehingga berdampak pada kualitas pelayanan di puskesmas. Tujuan dari penyusunan artikel ini adalah untuk memberikan gambaran terkait informasi pelayanan waktu tunggu resep obat racik dan non racik yang ada di puskesmas. Pencarian artikel ini mencakup berbagai publikasi mengenai waktu tunggu resep di puskesmas melalui Google Scholar dengan metode Boolean Operator (AND, OR) Kriteria inklusi dalam pencarian artikel yang relevan terdiri dari artikel yang dipublikasikan antara tahun 2016-2026 dan tersedia dalam teks lengkap gratis. Hasil seleksi artikel yang dilakukan, diperoleh 9 artikel jurnal yang memenuhi kriteria inklusi. Berdasarkan 9 artikel tersebut, sebanyak 3 artikel menunjukkan bahwa waktu tunggu pelayanan resep obat racik atau non racik sudah sesuai standar, dan sebanyak 6 artikel menyatakan masih terdapat waktu tunggu pelayanan resep obat racik atau non racik yang belum sesuai standar berdasarkan Permenkes atau puskesmas terkait.

Micro-teaching serves as a critical bridge between pedagogical theory and professional practice for pre-service teachers. In the context of Islamic Education (PAI), students are required to balance modern teaching methodologies with religious values. Objective: This study aims to explore the lived experiences of PAI students and identify their practical contributions to the Micro Teaching program at UNSIQ. Methods: Using an Interpretative Phenomenological Analysis (IPA) approach, this qualitative study involved 12 purposively selected students. Data were collected through semi-structured interviews, participant observations, and documentation during an intensive period from January 2 to January 30, 2026. Results: The findings reveal a significant transformation from "pedagogical anxiety" to professional confidence. Key contributions include the integration of Technology- Pedagogy-and-Content Knowledge (TPACK) through gamification in Fiqh subjects and the development of "Al-Qur’an-based Storytelling" rooted in local wisdom. Conclusion: The study concludes that the micro-teaching program at UNSIQ effectively fosters innovative and religious-humanist teaching identities, preparing students for the complexities of 21st-century Islamic education.

This study examines the implementation of Indonesian Language learning in higher education as a foundation for developing students’ academic literacy within an Outcome Based Education (OBE) framework. The research is motivated by serious concerns regarding students’ low academic writing ability, weak critical reading skills, and inconsistent use of academic language, which hinder the formation of academic culture at universities. The objective of this study is to describe and interpret the learning process, challenges, and outcomes of Indonesian Language courses in fostering academic literacy. This research employed a qualitative descriptive approach conducted intensively over a three-week period. Data were collected through classroom observations, in depth interviews with lecturers and students, and document analysis of lesson plans, teaching materials, and students’ academic assignments. The findings reveal that although the course design conceptually aligns with OBE principles, its classroom implementation has not fully emphasized reflective processes, critical engagement, and consistent academic language practice. Learning activities tend to focus on task completion rather than on the development of academic thinking processes. The study implies that Indonesian Language learning should be strengthened through reflective, contextual, and process oriented strategies to enhance students’ academic literacy and academic identity. These findings contribute theoretically to studies on academic literacy and practically to the improvement of Indonesian Language instruction in higher education.

Indonesian language education plays a strategic role in strengthening national identity and preserving cultural values amid the pressures of globalization. In the global era, the dominance of foreign languages, digital media, and transnational cultures poses challenges to the existence of national languages and local cultural identities. This study aims to analyze the role of Indonesian language education as an instrument for reinforcing national identity and cultural awareness in formal educational settings. The research employs a qualitative descriptive method with a literature review approach, examining scientific journals, policy documents, and relevant educational studies published within the last five years. Data were analyzed through content analysis to identify patterns, themes, and conceptual relationships related to language education and cultural identity. The findings reveal that Indonesian language education not only functions as a medium of communication but also serves as a vehicle for transmitting national values, cultural narratives, and collective identity. Learning materials that integrate local wisdom, literature, and cultural texts significantly contribute to students’ cultural awareness and national character development. Furthermore, Indonesian language education plays an important role in fostering critical literacy, cultural resilience, and a sense of belonging among learners in a globalized context. The study implies that strengthening Indonesian language education through curriculum development, contextual learning, and teacher competence enhancement is essential to sustaining national identity and cultural continuity in the era of globalization.

This study examines students’ understanding and application of Qawāʿid al-Fiqhiyyah in their daily muamalah practices and its implications for their ethical behavior. Using a descriptive qualitative approach, the research involved twenty students who provided data through questionnaires, in-depth interviews, and observations. The findings indicate that most students possess a solid understanding of the function of legal maxims as general principles guiding Islamic legal reasoning and as analytical tools for addressing contemporary issues. They are able to apply Qawāʿid al-Fiqhiyyah in various modern activities, such as digital transactions, social interactions, and financial management, which helps them act with greater caution, fairness, and responsibility. Nevertheless, several challenges remain, including difficulties in understanding Arabic terminology, limited contextual examples, and environments that do not always support consistent application. This study concludes that strengthening practical understanding and contextual learning is essential for Qawāʿid al-Fiqhiyyah to function effectively as a moral and Sharia-based guide for students navigating the complexities of modern life.

This article aims to analyze the role of human resource management in improving organizational performance and formulate strategic recommendations based on improvements in human resource management practices. The theoretical foundations used include strategic human resource management theory, organizational performance theory, and work motivation theory, which are used to examine the functions of workforce planning, competency development, performance appraisal, and reward systems. This study employed a qualitative, descriptive-analytical approach, with data collection techniques including in-depth interviews, non-participant observation, and documentation studies. Data analysis was conducted using an interactive qualitative analysis model that encompasses data reduction, data presentation, and conclusion drawing. The analysis results indicate that workforce planning based on organizational needs, continuous competency development, an objective performance appraisal system, and a performance-based reward system are directly related to increased effectiveness, productivity, and stability of organizational performance. Furthermore, efforts to improve human resource management practices through policy evaluation, strengthening strategic planning, enhancing internal communication, and data-driven decision-making have proven to be a strong foundation for formulating strategic recommendations for the organization. The study's conclusions confirm that the systematic and strategic integration of human resource management functions is a key factor in achieving sustainable organizational performance and adapting to changes in the work environment.

The juridical issues concern the limits of military criminal jurisdiction, patterns of sentencing for soldiers, command responsibility, and their implications for the principles of civilian supremacy and equality before the law. This study aims to analyze the implications and provide a comparative assessment of the expansion of the Indonesian National Armed Forces’ (TNI) authority following Law Number 3 of 2025 concerning the Amendment to Law Number 34 of 2004, particularly in relation to the addition of civilian positions that may be occupied by active-duty soldiers and the expansion of Military Operations Other Than War (OMSP). This research employs a normative juridical method with statutory, conceptual, and comparative approaches, using data sources in the form of legislation as well as national and international legal literature, which are analyzed qualitatively with deductive reasoning in drawing conclusions. The results of the study indicate that, first, the criminal law implications of the post-expansion of the TNI’s authority and roles give rise to the potential emergence of official offenses (delicta propria), particularly in the implementation of OMSP and the assignment of active-duty soldiers to civilian positions, which may generate ambiguity in judicial forums and criminal accountability; and second, a comparison with the military sentencing systems in the Netherlands and the United States demonstrates the importance of clear classification of offenses, a clearer separation between military jurisdiction and civilian courts, and the strengthening of due process of law, as well as effective civilian oversight to ensure the professionalism and legal certainty of the TNI.

The third trimester of pregnancy is a challenging period since pregnant women experience various physical and psychological changes that can affect their readiness for childbirth. High anxiety levels and the presence of pregnancy complications are known to reduce maternal preparedness for labor. This study aims to determine the relationship between anxiety levels and pregnancy complications with the readiness of third trimester pregnant women in facing childbirth in the working area of Benteng Community Health Center, Selayar Islands Regency. This research used a quantitative approach with a correlational design and a cross-sectional method. The population consisted of all third trimester pregnant women, with a total sample of 86 respondents selected using purposive sampling. The research instruments included an anxiety questionnaire using the Hamilton Anxiety Rating Scale (HARS), a pregnancy complication checklist, and a childbirth readiness questionnaire. Data were analyzed using the Chi-Square test and multiple logistic regression at a significance level of α = 0.05. The results of the study showed no significant relationship between anxiety and readiness for childbirth (p < 0.550) or between pregnancy complications and readiness for childbirth (p < 0.690). Therefore, it can be concluded that anxiety and pregnancy complications are not significantly related to the readiness of pregnant women in the third trimester for childbirth. This indicates that maternal readiness is influenced by factors other than the variables studied, such as knowledge, family support, and previous childbirth experiences.

This study aims to design a drug inbound and outbound transaction application that can improve the effectiveness and efficiency of drug data management at the UPTD Pharmacy Installation of Tanjungbalai City. The research method used in this study is a descriptive qualitative method with a case study approach. Data collection was carried out through direct observation at the research location, interviews with pharmacy staff, and documentation studies of documents related to drug management. The data obtained were then analyzed to identify weaknesses in the current system and determine the system requirements to be designed. The results of the study indicate that the existing manual recording system has not been able to support optimal drug management because it is less effective and prone to errors. The drug inbound and outbound transaction application designed in this study can assist pharmacy staff in recording incoming and outgoing drug data, monitoring drug stock in real-time, and generating reports automatically.

Injuries represent a common health issue associated with physical activity in both recreational and competitive sports settings. Appropriate initial management is essential to prevent complications and to facilitate optimal recovery. This study aims to describe the management of minor sports injuries at the Surisina Primary Health Center based on observational findings Sports and structured interviews with healthcare professionals. The study employed direct observation and structured interviews involving physicians and nurses at Surisina Primary Health Center on November 24, 2025. The findings indicate that sports injury management at the primary healthcare level involves a systematic initial assessment, comprehensive physical examination, and the implementation of simple immobilization techniques tailored to the type and severity of injury. Common injuries treated include sprains, muscle cramps, contusions, lacerations, ankle injuries, and minor fractures. Despite limitations in the availability of immobilization equipment, healthcare services were delivered effectively, supported by adequate patient education on injury care, warning signs, and activity recommendations during recovery. This study demonstrates the critical role of primary health centers in providing initial sports injury management and serving as practical learning sites for students in physical education and health programs.  

This research aimed to evaluate the implemention of the self assessment system in the collection of taxes on certain goods and services no food and/or beverages (restaurant tax) in increasing local revenue in Sikka Regency. This research was based on the fact that the realization of restaurant tax revenue has not yet been optimal, which was caused by dishonesty amomg taxpayers in reporting their sales turnover. The research method used in techniques including interviews, observation, and document studies. The results of this research indicated that the evaluation of the implemention of the self assessment system in the collection of taxes on certain goods and services on food and/or beverages (restaurant tas) in creasing local revenue has been carried out following the provisions of the applicable regional regulations but has not yet been fully optimal. This was due to the challenges and constraints faced by the Regional Revenue Agency in collecting restaurant taxes. The challenges encountered include dishonesty among taxpayers in reporting their sales turnover, while the constraints include the low level of  awareness and understanding of taxpayers regarding procedures for self-calculation, reporting, and payment. However, the Regional Revenur Agency has undertaken various efforts or strategies to increase restaurant tax revenue in Sikka Regency, such as conducting spot checks, implementing education and socialization programs, utilizing and installing technological tools such as M-Pos, and enforcing strict supervision to improve restaurant tax revenue targets and enchance local revenue in Sikka Regency, so that more optimal targets can be achievied

College represents a critical transitional period requiring high adaptation, where students often face escalating academic demands triggering psychological pressure. This study aims to deeply analyze the reciprocal relationship between sleep patterns and academic stress levels, and identify their subsequent impacts on cognitive function (concentration) and students' physical health. This study employs a qualitative method with a Systematic Literature Review approach. Data were collected through comprehensive searches of accredited national and reputable international scientific articles published within the last five years (2020–2025). Literature selection was conducted rigorously using specific keywords to screen empirical studies relevant to stress, sleep, and student health variables. Data synthesis reveals a strong and consistent negative correlation. High levels of academic stress whether stemming from the adaptation phase of new students (initiation), thesis preparation workload, or role conflicts in working students are significantly associated with decreased sleep quality. Physiologically, stress triggers increased cortisol levels causing insomnia, shortened sleep duration, and prolonged sleep latency. Subsequent impacts are proven to drastically reduce learning concentration and trigger physical health disorders, including an increased risk of primary dysmenorrhea in female students. This study concludes that academic stress and sleep disturbances form a destructive cycle that exacerbates one another. Therefore, holistic institutional interventions in the form of sleep hygiene education and stress management training are needed to break this chain for the sake of student well-being and academic performance.

This study aims to identify and describe the values of Islamic education embedded in the art of Rampak Barongan Dance performed by the Krido Turonggo Mudo Art Studio in Koya Barat Subdistrict, Jayapura City, as well as to analyze this artistic practice as a medium for character education and cultural da’wah within the community. This research employs a qualitative method with a descriptive approach, focusing on an in-depth understanding of the meanings and practices of Islamic values in artistic activities. Research data were collected through direct observation, in-depth interviews with the studio managers and members, and documentation related to the dance training and performance processes. The collected data were analyzed interactively through the stages of data reduction, data display, and conclusion drawing to obtain systematic and comprehensive results. The findings indicate that the Rampak Barongan Dance contains Islamic educational values, including faith (aqidah), sharia, morality (akhlak), and social values. These values are reflected in prayers before performances, the use of modest attire in accordance with Islamic sharia, sincerity in performance, social ethics, solidarity, and teamwork. The practice of training and performing the dance serves as a means of cultivating discipline, responsibility, respect for time, and functions as an effective medium of cultural da’wah by integrating artistic aesthetics with Islamic moral messages.

In demographic studies, population growth refers to changes in the number of inhabitants over a given period, measured by calculating numerical differences in population size and expressing them within specific time units to illustrate patterns of increase or decline. Based on data from Tembalang District in Figures 2025, the population growth rate in Kedungmundu Village rose by 0.51% between 2016 and 2025, with most residents relying on clean water services provided by PDAM Tirta Moedal as their primary source of drinking water. This study aims to estimate clean water demand based on projected population growth and to design a pipeline network system capable of meeting future needs. The analysis of water demand applies population projection methods, including arithmetic, geometric, and least square approaches, to compare their levels of accuracy, while the clean water distribution network is modeled using EPANET 2.0. One of the main challenges faced by PDAM is that service coverage has not yet been fully optimized. The ten-year projection results indicate that the arithmetic method provides a correlation value closest to 1, estimating a future population of 14,904 people with a total clean water requirement of 3.48 liters per second. To support this projected demand, the proposed network design utilizes High Density Polyethylene (HDPE) pipes with diameters of 12, 10, and 8 inches to ensure efficient and sustainable water distribution.

Employee cooperatives play a strategic role as an economic buffer for teachers and school staff, particularly in providing access to safe, transparent, and equitable financial services. This study aims to evaluate the salary and share deduction system in managing member loans at the “Maju Terus” Employee Cooperative of SMKS Yohanes XXIII Maumere. The evaluation focuses on salary deduction procedures for active members, share deduction mechanisms for inactive members, handling of arrears, system effectiveness, obstacles encountered, causes of obstacles, and improvement efforts that have been made. The research method used is a descriptive qualitative approach with data collection techniques through observation, interviews, and documentation studies. The study results show that the salary and share deduction system has been implemented in a structured and effective manner, successfully maintaining the non-performing loan rate below 2% for the past three years, as well as supporting cash flow stability and increasing cooperative revenue. However, the implementation of this system still faces obstacles such as late payment of salary deductions by the school treasurer, insufficient shares of inactive members to cover arrears, a manual recording system, and minimal outreach to new members. Improvement efforts that have been made include monthly coordination meetings, intensive outreach, transparency through membership books, quarterly reporting, and the implementation of moral sanctions. These findings confirm that the salary and share deduction system is not only a loan security tool, but also a concrete manifestation of cooperative values: kinship, collective responsibility, and economic justice.

The prevalence of diabetic ulcers in Indonesia reaches 12-15% of all sufferers. This condition has an impact on the patient's psychological condition in the form of anxiety due to wounds that are difficult to heal, changes in body image, and concerns about the possibility of amputation. One of the nonpharmacological interventions that can help overcome anxiety is the slow deep breathing technique. The purpose of writing this scientific paper is to carry out Nursing Care for Mrs. M with Diagnosis of Diabetic Ulcers using the application of slow deep breathing intervention in reducing anxiety at Az-Zahra Hospital. The writing method is a nursing care process that includes the stages of study, nursing diagnosis, planning, implementation, and evaluation. The subject of care was Mrs. M, a patient with diabetic ulcers in the inpatient room of Az-Zahra Hospital. Data collection was carried out through interviews, observations, documentation studies, and physical examinations, and using a medical-surgical nursing care assessment format. The ethical principles applied use the principles of Nursing Ethics. The results of nursing care showed that after three days of slow deep breathing intervention, patients reported feeling calmer, sleeping better, and anxiety levels decreased from moderate to mild based on observation results and anxiety scales used. This suggests that slow deep breathing interventions are effective in helping to reduce anxiety in patients with diabetic ulcers. It is hoped that patients and families can continue these breathing exercises independently as part of stress management efforts and quality of life improvement.  

Injuries, supported by continuous education, plays an essential role in preventing further injury and Sports injuries are common occurrences in physical activities, with minor injuries being the most frequently experienced by athletes, students, and the general community. Improper initial management of minor sports injuries may lead to more severe conditions and prolonged recovery periods. This study aimed to describe the management of minor sports injuries at Boawae Public Health Center based on observation and interviews with healthcare professionals. A descriptive qualitative method was employed through direct observation and structured interviews with a general practitioner and a nurse at Boawae Public Health Center. The results indicated that the most common minor sports injuries treated were contusions, mild sprains, muscle cramps, and muscle soreness. The initial management applied by healthcare providers was based on the RICE principle (Rest, Ice, Compression, and Elevation), accompanied by injury assessment before and after treatment. In addition, patients were provided with education regarding proper injury management and injury prevention. It can be concluded that appropriate early management of minor sports ensuring safe and sustainable participation in sports activities.