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Chronic kidney disease (CKD) is a global health problem with continuously increasing prevalence and mortality. This condition is characterized by a progressive and irreversible decline in kidney function, which is clinically assessed using the estimated glomerular filtration rate (eGFR) as one of the main parameters for staging and monitoring disease progression. Red blood cell distribution width (RDW) is a hematological parameter that reflects the degree of variation in erythrocyte size. In patients with CKD, elevated RDW levels are often associated with oxidative stress and chronic inflammation, which may accelerate kidney damage and increase mortality risk. To analyze the correlation between RDW and eGFR values in patients with chronic kidney disease at ODSK Hospital, North Sulawesi Province. This study used an analytical observational design with a cross‑sectional approach. It was conducted retrospectively using secondary data from the medical records of CKD patients at ODSK Hospital, North Sulawesi Province, from February 2024 to August 2025. This study used a total sampling method with 189 CKD patients who met the inclusion and exclusion criteria.  Based on Spearman-rank correlation analysis, the p‑value obtained was 0.129 (>0.05). There was no significant relationship between RDW and eGFR values in CKD patients at ODSK Hospital, North Sulawesi.Province.

The increasing prevalence of metabolic syndrome and chronic kidney disease underscores the need for simple, low-cost, and community-applicable screening indicators. This study aimed to evaluate the association between basic anthropometric parameters and blood pressure, metabolic indicators, and renal function among adults in the Badui Luar community. A cross-sectional design was employed involving 41 participants who underwent anthropometric assessment, biochemical measurements, and blood pressure evaluation. Pearson correlation analysis was used to examine linear associations between variables. The results demonstrated that neck circumference exhibited significant correlations with dyslipidemia components, including LDL (r = 0.377), TC/HDL ratio (r = 0.516), and HDL (r = –0.433), indicating cervical adiposity as a strong marker of atherogenic risk. Calf circumference showed protective correlations with fasting glucose (r = –0.352) and eGFR (r = 0.322), suggesting the metabolic relevance of peripheral muscle mass in glycemic regulation and renal status. Body mass index showed a weak correlation with systolic blood pressure (r = 0.149), whereas waist and hip circumferences exhibited mild, clinically insignificant correlations with triglycerides and total cholesterol. Overall, these findings highlight that simple anthropometric measures—particularly neck and calf circumference—may serve as early indicators of cardiometabolic and renal risk in community-based screening. Further longitudinal studies with larger and more heterogeneous populations are required to validate these associations and determine the predictive power of anthropometric indicators.

Low back pain (LBP) is one of the most common musculoskeletal complaints globally and is the main cause of decreased work productivity. One of the risk factors that has been widely studied in the literature is prolonged sitting duration. Prolonged sitting activities cause increased static pressure on the lumbar spine, fatigue of the supporting muscles, as well as a decrease in local blood flow that can trigger chronic pain. This study is a literature review with a meta-analytical approach that aims to analyze the relationship between long-term sitting and the incidence of LBP. The review process was carried out following PRISMA guidelines through searches on PubMed, Scopus, ScienceDirect, and Google Scholar databases for publication in 2020–2025. Of the 20 previous studies analyzed, most showed a positive association between sitting time and an increased risk of LBP, both in adults, adolescents, and children. Sitting for more than 6 hours per day increases the risk of LBP by 33%, especially in individuals with low physical activity. In addition, longer sitting durations with poor posture and minimal active rest were found in the group of office workers and professional drivers who had a high prevalence of LBP. Physical activity has been shown to play a protective role against the risk of LBP, while ergonomic interventions such as lumbar support can reduce pain complaints. Although most studies were observational, the consistency of results supports the importance of prevention through reduced sitting time, increased physical activity, and ergonomic work environment settings. These findings provide a scientific basis for multidimensional interventions to effectively reduce the incidence of LBP.  

Epistaxis, or more commonly known as nosebleeds, is one of the most frequently encountered medical emergencies in the field of ENT. Epistaxis is a condition in which blood flows from the nasal cavity. Although often considered a minor disorder, epistaxis can be a sign of a more serious medical condition, especially if it occurs repeatedly or in large amounts. Globally, the prevalence of epistaxis is estimated to be around 21.7%, with a wide range of variation between countries, namely between 3 and 60 cases per 100,000 population per year. This paper aims to review the aspects of diagnosis and management of epistaxis based on the latest literature. The method used in this study was a search and analysis of various scientific publications, guidelines, and relevant current journals. The discussion covers the identification of types and signs of epistaxis, emergency management, and tampon insertion strategies. Understanding the appropriate and rapid diagnosis and management is essential to prevent the condition from worsening.

Concurrent stunting and overweight/obesity (CSO) in adolescents represents a complex form of the double burden of malnutrition, characterized by linear growth faltering coexisting with excess body fat. This condition poses significant metabolic, cognitive, and reproductive risks that may affect long-term health and productivity. This review employs a narrative literature approach by synthesizing evidence from PubMed, Scopus, Web of Science, Google Scholar, and national journal portals. Included literature comprises studies assessing stunting, overweight/obesity, metabolic risk, cognitive function, and reproductive health among adolescents. Indonesian evidence (Harits et al., 2024) indicates that obese adolescents with a history of stunting exhibit a higher prevalence of metabolic syndrome (18.75%), greater abdominal adiposity, and elevated systolic blood pressure compared to non-stunted obese peers. Biologically, stunting impairs neurocognitive development and reduces muscle mass, while obesity promotes metabolic inflammation; the coexistence of these factors may reduce physical fitness, learning capacity, and overall productivity. CSO also affects reproductive health, including increased risks of ovulatory dysfunction, delayed sexual maturation, and intergenerational nutritional disadvantages. Although linear growth recovery is limited due to epiphyseal closure, functional recovery through improved diet quality and physical activity remains possible. In conclusion, adolescents with CSO experience greater metabolic, cognitive, and reproductive vulnerabilities than those affected by stunting or obesity alone. Interventions emphasizing metabolic function, diet quality, physical fitness, and reproductive health preparation are essential to prevent long-term consequences and break the intergenerational cycle of malnutrition. Further national research is required to map the prevalence and implications of CSO comprehensively.

Myopia is a multifactorial disease, affected by various hereditary and environmental conditions. This literature review aims to evaluate the association between risk factors in incidence of myopia in children aged 6 to 12 years old. A cross-sectional study of elementary students in MI Patihan Kidul, Ponorogo, East Java was performed. Eligible samples were 6 to 12 years old students. Examination was performed on September 7th 2023. The students underwent short history taking, body mass index (BMI), and visual acuity examination. Age, sex, BMI, family history of myopia, sleeping time, screen time, and duration of outdoor activity were examined as risk factors. A total of 336 children met the inclusion criteria, of which 48 (14.2%) of them had myopia. Family history of myopia was proven to increase the risk for myopia on their children (p value 0.012, OR 0.436).  Heredity is a well-established risk factor for myopia. This literature review provides evidence on the positive correlation between family history and the occurrence of myopia in children. 

The increasing proportion of the elderly population in Indonesia has led to a rise in degenerative health problems, one of which is osteoporosis. Osteoporosis is a bone disease characterized by decreased bone density, increasing the risk of fractures, particularly among elderly women. Low calcium intake, lack of physical activity, and limited knowledge regarding osteoporosis prevention are major contributing factors. This community service activity aimed to improve the knowledge of Aisyiyah women in Cirebon Regency regarding osteoporosis in the elderly, including its definition, risk factors, impacts, and prevention strategies through proper nutrition and regular physical activity. The activity was conducted from October to December at the Aisyiyah Study Hall in Cirebon Regency, targeting pre-elderly and elderly women. The methods used included health education through lectures and interactive question-and-answer sessions, supported by laptops, LCD projectors, and PowerPoint presentations. Evaluation of participants’ knowledge was carried out using oral pre-tests and post-tests related to the delivered material. The results indicated an improvement in participants’ understanding of osteoporosis, the importance of adequate calcium intake, and the role of physical activity in maintaining bone health. This community service program is expected to contribute to increasing health awareness and reducing the risk and prevalence of osteoporosis among the elderly.

This study examines the short story "Click that Kills" by Taufiqurohman to reveal the position of humans in the increasingly dominating digital algorithm environment. Using a descriptive qualitative approach that focuses on structural analysis and literary psychology based on Freud's psychoanalytic theory, this study thoroughly analyzes the intrinsic elements as well as the inner conflicts of the characters. The findings of this study show that the AIDA system poses a profound existential crisis, where individual freedom is threatened due to systemic information manipulation. The characters of Dito and Genta experience a serious conflict between id, ego, and superego when dealing with the figure of "Shadow User" who is a real symbol of the shift in human dignity through raw data. In terms of structure, the storyline conveys a deep social critique of the loss of human self-control in cyberspace. This research shows that this short story is a premonious criticism of the importance of maintaining the essence of humanity in the midst of the prevalence of mechanical algorithms. The phenomenon emphasizes that digital technology can potentially alienate the moral consciousness of individuals in modern society.

Chronic Kidney Disease (CKD) is a global health problem with a continuously increasing prevalence and mortality rate. Global data indicates that kidney disorders have affected more than 850 million people, with CKD being one of the leading causes of death. North Sulawesi is recorded as one of the provinces with the highest prevalence of CKD. Blood creatinine is used as the primary marker of kidney function, while hypertension is a comorbidity commonly found in CKD patients and can act as both a cause and a consequence of impaired kidney function. Several studies have reported varying results regarding the relationship between creatinine levels and blood pressure. Purpose to analyze the association between serum creatinine levels and blood pressure in chronic kidney disease patients with hypertension at ODSK Hospital, North Sulawesi Province. Methods the research design used an observational analytic cross-sectional design. This study used an observational analytic cross-sectional design. It was a retrospective study utilizing secondary data from medical records for the period of June 2022 to August 2025. Total sampling method was employed with a sample size of 65 patients who met the inclusion criteria. Based on the Spearman correlation test results, the significance values between creatinine and systolic pressure was 0.685, and between creatinine and diastolic pressure was 0.787 (p-value >0.05). There is no significant correlation between serum creatinine levels and blood pressure in chronic kidney disease patients with hypertension at ODSK Hospital, North Sulawesi Province.

Type 2 Diabetes Mellitus (T2DM) is a global health problem with continuously increasing prevalence, covering the majority of diabetes cases worldwide. Persistent hyperglycemia in T2DM progressively damages the kidneys. Early assessment of kidney function, especially through the examination of urea levels and estimated glomerular filtration rate (eGFR) values, is important to predict CKD prognosis and guide therapeutic intervention. To discover the profile of urea levels and eGFR values in Type 2 Diabetes Mellitus patients at ODSK Hospital, North Sulawesi Province. This study is a descriptive quantitative observational study with a cross-sectional design, conducted retrospectively using secondary data from the medical records of Type 2 Diabetes Mellitus patients at ODSK Hospital, North Sulawesi Province during the period February 2024–August 2025 who met the inclusion criteria. From a total sample of 658 Type 2 Diabetes Mellitus patients, the majority of patients had high urea levels (53.3%). Based on sex, the proportion of high urea levels in males (57.2%) was higher compared to females (50.5%). Meanwhile, the distribution of eGFR values showed that the G1 category was the most frequent (23.9%). However, the majority of other patients (75.1%) were already in categories G2 to G5, which indicates a decrease in kidney function. This decrease in kidney function was slightly more detected in male patients (76.1%) compared to female patients (74.4%). Type 2 Diabetes Mellitus patients at ODSK Hospital, North Sulawesi Province, have high urea levels and the majority have decreased eGFR values.

The nutritional status of toddlers is an important indicator that reflects the level of public health in a region. This study aims to analyze the nutritional status of children aged 0–5 years in Teupin Desa Teupin Gapeuh Kecamatan Tanah Pasir Kabupaten Aceh Utara. This research employed a descriptive quantitative method using secondary data obtained from health records and posyandu (integrated health post) reports. The study involved a total of 60 children under five, consisting of 33 boys and 27 girls. The findings revealed that based on the weight-for-age (W/A) index, 81.7% of children had normal nutritional status, 13.3% were undernourished, and 3.3% were severely undernourished. Based on height-for-age (H/A), 90.0% were normal, 5.0% were short, and 3.3% were very short. According to the weight-for-height (W/H) index, 83.3% were normal, 11.7% were undernourished, and 5.0% were at risk of overweight. Furthermore, the prevalence of stunting, wasting, and underweight were 8.3%, 11.7%, and 16.7% respectively. These results indicate that although most children have normal nutritional status, some still experience nutritional deficiencies that require special attention. Therefore, health workers and local governments need to strengthen nutrition education programs, increase community awareness of balanced nutrition, and improve monitoring of child growth to prevent malnutrition in the area

The prevalence of correct handwashing behavior with soap in Aceh Province is 36%. School-age children are the time to instill PHBS values ​​and have the potential to be agents of change to promote PHBS both in the school environment, family, and society. The impact of lazy handwashing with soap can cause various diseases such as diarrhea, flu, hepatitis A, and impetigo (a contagious infection that usually occurs in children who rarely wash their hands, this disease is characterized by red skin which then develops into small blisters). The purpose of this study is to determine the effectiveness of mini posters as a health promotion media on handwashing behavior with soap in elementary school students. The research method is one group pretest posttest design. The sampling technique is total sampling, while the number of samples in this study was 80 students from grades 5 and 6 of elementary school. The results of the study obtained before the intervention of mini posters washing hands with soap behavior of elementary school students 77.5% of students did not wash their hands with soap after urinating and defecating. After the intervention of mini posters washing hands with soap behavior of elementary school students 87.5% did wash their hands with soap. There is an effect of mini poster intervention on increasing handwashing behavior in elementary school students with a p value of 0.000 < 0.05. The results show that mini posters are a reference for the effectiveness of health promotion in preventing infectious diseases in elementary school children by implementing a handwashing program with soap in the school environment

Introduction: Triglycerides are a lipids fractions that play an important role in energy metabolism, but high levels in the blood are strongly associated with increased risk of cardiovascular disease, metabolic syndrome, and type 2 diabetes. The prevalence of hypertriglyceridemia tends to increase, including in urban area such us West Jakarta which have high risk consumption patterns. This community service activity aimed to raise public awareness about the importance  lipid profile management with screen triglyceride levels in community of Kelurahan Kota Bambu. Method: The activity was conducted in June 2025, involving 168 adult participants. The method was used was health education on the role of triglycerides and their risk,, followed by laboratory testing using the Nesco BL-101 5in1 Lipid Panel Monitoring System. Triglyceride level was classified into normal, borderline, high, and very high categories according to the NCEP ATP III guidelines. Results: The average triglyceride level of the participants was 181.21 mg/dL, with a range of 47–830 mg/dL. The triglyceride levels of the majority of participants were in the normal category, but the proportion with high and very high triglyceride levels was significant, indicating the existence of a risk group that needs attention. Conclusion: This activity confirms that simple triglyceride testing at the community level can be an effective step in early detection, education, and prevention

Tilapia Lake Virus (TiLV) is an RNA pathogen that causes high mortality rates in tilapia (Oreochromis niloticus), posing a major threat to global aquaculture. This study aimed to detect the presence of TiLV in tilapia populations in East Kalimantan Province, Indonesia, using the Polymerase Chain Reaction (PCR) method. A total of 60 tilapia samples were collected from three main aquaculture areas: Kutai Kartanegara, Samarinda, and Penajam Paser Utara. Molecular analysis revealed that one sample from Penajam Paser Utara was positive for TiLV, with an overall prevalence of 5%, while all samples from other sites tested negative. This finding indicates that TiLV has been molecularly detected in East Kalimantan, albeit at a low prevalence. The overall prevalence of TiLV infection in East Kalimantan was 1.67%. The results provide important baseline data for strengthening disease surveillance, biosecurity implementation, and the development of preventive strategies in tilapia aquaculture systems in Indonesia.

The phenomenon of burnout has evolved into a significant occupational health problem with a prevalence reaching 82% across various global work sectors, especially post-COVID-19 pandemic. This study aims to identify and analyze the causal factors of burnout through a systematic literature review approach using PRISMA 2020 guidelines. Literature search was conducted on four main electronic databases yielding 309 articles which were then selected down to 10 high-quality articles meeting inclusion criteria for the 2021-2025 publication period. Synthesis results indicate that burnout is a multidimensional phenomenon influenced by complex interactions between organizational and individual factors. Dominant organizational factors include work overload, lack of managerial support, unsafe working conditions, and resource inadequacy with burnout prevalence ranging from 17-94%. Individual factors encompass demographic characteristics, coping strategies, resilience, and internal psychological conflicts that serve as moderator variables. Job satisfaction and work meaningfulness function as mediator variables connecting organizational conditions with burnout outcomes. These findings provide theoretical contributions in understanding burnout etiology and can practically serve as a foundation for developing evidence-based preventive interventions to reduce burnout prevalence in work environments.

Stunting remains one of the major chronic nutritional problems in Indonesia, including in Oesapa Village, Kelapa Lima District, Kupang City, East Nusa Tenggara Province. This condition is not only caused by inadequate nutritional intake but is also closely related to chronic infections resulting from poor hygiene and sanitation, particularly intestinal parasitic diseases. To reduce the risk of parasitic infections and improve children’s nutritional status, preventive efforts through education and health promotion are essential.This community service activity aimed to increase public awareness and knowledge, especially among parents and caregivers of stunted children, regarding the importance of maintaining hygiene and sanitation to prevent intestinal parasitic diseases. The methods used included participatory approaches such as interactive lectures, group discussions, and practical demonstrations of clean and healthy living behavior (PHBS), food hygiene, clean water management, and household waste disposal. Evaluation was conducted using pre-test and post-test instruments to measure changes in participants’ knowledge.The activities, carried out from May to September 2025 in Oesapa Village, showed a significant improvement in community understanding of hygiene and sanitation practices. Participants demonstrated greater commitment to maintaining environmental cleanliness and adopting healthier daily behaviors. Continuous educational efforts and multisectoral support are needed to help reduce the prevalence of stunting in the region

Smoking behavior among adolescents remains a major public health issue due to its high prevalence and potential long-term effects on physical, psychological, and social health. One key factor influencing adolescent behavior is the family environment. A family approach that incorporates effective communication, parental supervision, role modeling, emotional support, and consistent enforcement of rules is believed to significantly impact the prevention and reduction of smoking behavior in adolescents. This study aims to analyze the effect of a family approach on smoking behavior in adolescents. Adolescents who experience open communication, good supervision, and emotional support from their families tend to exhibit stronger self-control and are more likely to resist peer pressure to smoke. The findings suggest that an optimal family approach is crucial in shaping healthy behavior in adolescents and serves as an effective strategy in smoking prevention efforts. This approach not only helps in reducing smoking behavior but also fosters overall well-being by creating a supportive family environment. In conclusion, family involvement plays an essential role in promoting healthier behaviors in adolescents and preventing smoking, contributing significantly to public health improvement

Non-communicable diseases (NCDs) are the leading causes of morbidity and mortality, particularly among older adults. Integrated Development Posts for Non-Communicable Diseases (Pos Pembinaan Terpadu Penyakit Tidak Menular / Posbindu PTM) play a crucial role in the early detection of NCD risk factors at the community level. This activity aimed to conduct NCD risk factor screening through the measurement of blood pressure, random blood glucose, total cholesterol, and uric acid levels, as well as to provide health consultations for participants of Posbindu Rosella, South Kembangan. The activity was conducted in November 2025 using a descriptive design. A total of 30 Posbindu participants were involved. Health examinations included blood pressure, random blood glucose, total cholesterol, and uric acid measurements. Data were analyzed descriptively and classified into normal and abnormal categories based on clinical guidelines. The majority of participants were female (80%), with a mean age of 60.5 ± 9.7 years. The mean systolic blood pressure was within the hypertensive range. Approximately 50% of participants had impaired glucose regulation, 60% experienced hyperuricemia, and 40% had total cholesterol levels classified as borderline or higher.  Health screening activities at Posbindu revealed a high prevalence of NCD risk factors among participants. Posbindu plays an essential role in early detection and community-based prevention of non-communicable diseases.

The study was conducted at Middle Technical University (College of Health & Medical Techniques, Baghdad) from 29Th October 2024 to 15Th January 2025, enrolling 148 students aged 20–24 years (47.3%), 25–29 years (41.9%), 30–39 years (9.5%), and over 40 years (1.4%), Participants completed a structured questionnaire to assess attitudes toward drug abuse. Regarding protective attitudes, 66.2% agreed that educational programs aid prevention, 68.9% viewed better education as protective, 58.8% cited close family ties, and 72.2% recommended avoiding friends who use drugs, Departmental analysis showed the highest proportion of ―good knowledge in Anesthesia Techniques (95.3%) and the lowest in Physical Therapy Techniques (80.2%) While overall awareness of drug abuse is high among health and medical students, misconceptions regarding its symptoms and effects persist. Targeted educational interventions—especially within departments showing lower knowledge—and reinforcement of accurate prevention and treatment strategies are recommended to strengthen students’ competencies in addressing drug abuse.

Background: Sleep disorders in adolescents are a significant health problem, with a global prevalence reaching 57.8% and particularly high rates in several cities in Indonesia. Poor sleep quality negatively impacts physical health, such as the risk of cardiovascular disease and anemia, as well as mental and cognitive health. Sleep behavior is influenced by a dynamic interaction between personal and environmental factors, as explained in Social Cognitive Theory (SCT). Research Objective: To identify the determinants of sleep deprivation in adolescents, specifically individual and environmental factors, based on a Social Cognitive Theory (SCT) perspective through a literature review from 2019 to 2025. Method: This study utilized a literature review. To obtain research data, the authors searched for scientific articles through Google Scholar, PubMed, and ScienceDirect databases, then analyzed 10 articles that met the inclusion criteria, published between 2020 and 2025. Results: Factors significantly associated with adolescent sleep quality were identified, with individual factors being the most dominant determinant (found in 7 studies), including academic stress and smartphone addiction. Furthermore, a positive association was found with environmental factors (found in 4 studies), such as bright lighting, noise, and uncomfortable room temperature. Conclusion: Within the framework of Social Cognitive Theory, adolescent sleep quality is the result of a reciprocal interaction between personal factors (perceived stress and self-control over gadgets), the physical environment, and sleep behavior. Individual factors such as stress and nighttime gadget use reduce self-efficacy for regular sleep, which is exacerbated by an unfavorable environment.