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Liver damage induced by hepatotoxic compounds such as N-acetyl-p-aminophenol (N-APAP) remains a significant global health concern. Hepatotoxicity caused by N-APAP, particularly in cases of overdose or prolonged use, can lead to a reduction in glutathione levels in the liver, resulting in oxidative stress and cellular damage. This condition contributes to an increased incidence of liver diseases, including toxic hepatitis and acute liver failure, which can lead to serious complications and even death. Although various pharmacological therapies, such as N-acetylcysteine (NAC), are available to address N-APAP-induced liver damage, limitations such as side effects, high costs, and variable efficacy have driven the search for safer and more affordable therapeutic alternatives. Therefore, research on natural hepatoprotective agents, such as extracts from the rhizomes of fingerroot (Boesenbergia rotunda), has become increasingly relevant in addressing this issue. The aim of this study was to evaluate the hepatoprotective potential of ethanol extract from fingerroot rhizomes (Boesenbergia rotunda) in protecting the liver from N-acetyl-p-aminophenol (N-APAP)-induced damage. Specifically, this research focuses on measuring glutathione levels as a key indicator of the liver's protective mechanism against oxidative stress. In this study, 30 male White rats were randomly divided into six groups, each consisting of five rats. All rats were orally administered the extract at predetermined doses for 10 consecutive days, except for the negative and positive control groups. On the 10th day, all groups (except group 1) were treated with paracetamol (800 mg/kg body weight) to induce liver damage. Twenty-four hours after induction, the rats were sacrificed and liver samples were collected. Glutathione levels were measured using the ELISA immunosorbent assay. Statistical analysis showed that administering the ethanol extract of Fingerroot rhizomes (EERTK) for 10 days prior to N-APAP induction significantly increased the average antioxidant enzyme GSH-Px levels in the liver homogenate of rats in the EERTK 250 mg/kg BW (43.36 ± 1.34 U/mg protein), EERTK 500 mg/kg BW (55.70 ± 2.15 U/mg protein), and 750 mg/kg BW (53.14 ± 2.57 U/mg protein) group compared to the negative control group (N-APAP 800 mg/kg BW), which had the lowest average antioxidant enzyme GSH-Px level (33.86 ± 3.52 U/mg protein).

Gundala (2019) can be seen as a work that not only entertains but also reflects and criticizes Indonesian social realities. This film conveys a message about the importance of courage and solidarity in facing social injustice, as well as raising issues that are relevant to society, such as corruption, economic inequality, and the struggles of the lower classes. This film by Joko Anwar represents heroic values such as courage, patience, willingness to sacrifice, and optimism, which not only inspires but also provides relevant moral learning, especially for the younger generation. This research aims to describe the heroic values displayed in Joko Anwar's Gundala (2019). This research uses a qualitative descriptive research method. The results of this research show that the heroic values found in the film Gundala (2019) by Joko Anwar are in accordance with Matta's (2004) theory. This theory reveals that heroic values contain four symbols, namely Courage, Patience, Willingness to Sacrifice, Optimism and implication.

Short stories are more popular among readers, especially young readers, because they are shorter than novels and contain fewer pages. Numerous moral lessons can be conveyed through short stories. Short stories serve as one of the methods for teaching morality to young readers among other approaches. This thesis examines the moral messages in the short story Dua Tengkorak Kepala by Motinggo Busye. The main research question of this study is: What are the moral messages contained in the short story Dua Tengkorak Kepala by Motinggo Busye? The purpose of this study is to identify the moral messages in the short story Dua Tengkorak Kepala by Motinggo Busye. This research employs a library research approach. Library research involves exploring various literature relevant to the issues being studied. The moral messages in the short story Dua Tengkorak Kepala by Motinggo Busye are categorized into three types: 1) religious moral messages, 2) moral messages regarding the relationship between humans and themselves, including courage, perseverance, responsibility, independence, honesty, and conscience, and 3) moral messages concerning the relationship between humans and others, which include obedience to parents, willingness to sacrifice, respecting others, and helping others.

The act of sacrifice (udhiyah) is a form of worship in Islam that holds profound spiritual and social values. Sacrifice aims to draw closer to Allah SWT while demonstrating solidarity with others through the distribution of meat to the community, especially those in need. However, the implementation of sacrifice is often not fully understood, particularly regarding its rulings and etiquettes, such as the selection of animals, slaughtering procedures, and meat distribution. This study aims to provide a comprehensive understanding of the rulings of udhiyah and the etiquettes of sacrifice based on Islamic law.The research employs a qualitative approach with a library research method. Data were collected from primary sources such as the Qur'an and hadith, as well as secondary sources including books of Islamic jurisprudence, scholarly journals, and other relevant literature. Data analysis was conducted descriptively to identify and organize systematic insights related to the topic.The results indicate that sacrifice is obligatory for those who can afford it according to some scholars, while the majority consider it a strongly recommended act (sunnah muakkad). The etiquettes of sacrifice include sincere intentions, selecting animals that meet Islamic requirements, proper and humane slaughtering, and proportional meat distribution. Sacrifice also holds spiritual wisdom, such as strengthening faith and gratitude, as well as social benefits by fostering community bonds through sharing.This study concludes that sacrifice is not merely an annual ritual but also a reflection of values such as devotion, sincerity, and solidarity that must be instilled continuously in the lives of Muslims.

Ludruk "Sogol Pendekar Sumur Gemuling" is a performing art work rich in human values. In this analysis, the theme of solidarity is highlighted through the interaction of characters who support each other in facing challenges. The courage of the characters in fighting for the truth and protecting the weak illustrates the essence of human struggle in everyday life. Intelligent and meaningful dialogues lead the audience to reflect on their role in the community, as well as the importance of respecting and helping each other. In addition, the sacrifices shown by the main characters provide a deeper dimension to the understanding of human values. These sacrifices are not only physical, but also emotional, reflecting the complexity of human relationships. Through these elements, this ludruk successfully invites the audience to absorb the importance of empathy and a sense of social responsibility. Thus, "Sogol Pendekar Sumur Gemuling" is not only entertainment, but also a means of reflection on the noble values that must be upheld in community life.

Movies can inspire, educate, or even influence the way we see things. movies about parents' struggles for their children can educate us all about how great parental love is in seeking justice for their children. The web series movie Cinta Pertama Ayah tells the story of a father's love and sacrifice to seek justice for his daughter. The purpose of this research is to find out the connotation and denotation meanings of father's love and the representation of father's love in this movie. The research method is using a qualitative approach with Roland Barthes semiotic theory analysis. The data collection technique uses documentation in the form of capturing movie scenes and literature study to find things related to this research. The results of this study show that there are many scenes that contain elements of representation of father's love which are divided into 4 scenes studied. The denotation and connotation meanings in the 4 scenes can be seen from the efforts to be willing to sacrifice, help the child overcome problems, support the child whatever happens. The connotation meaning is in the form of creating courage in children, emotional support when anxious and frustrated, embracing children when fear arises, teaching children what they don't know, and encouraging and always accepting the child no matter what.

The birth of various Islamic financial institutions (LKS) shows that Islamic teachings cover the economic scope, including cooperatives in the form of Islamic finance These Islamic teachings must absolutely be obeyed and guided by all Muslims in making daily life activities, including in transaction and investment activities, Mashlahah refers to all forms of benefits or goodness that can bring prosperity to individuals and society in general.  without ignoring sharia values. For manufacturers of mashlahah formulations, it is an important challenge in carrying out production activities that not only pursue material profits, but also contribute to economic sustainability, social justice, and environmental preservation Qualitative descriptive research is aimed at describing and describing existing phenomena, both natural and man-made, that pay more attention to the characteristics, quality, and linkages between activities. In addition, descriptive research does not provide treatment, manipulation or alteration to the variables studied, but rather describes a condition as it is. The only treatment given is the research itself, which is carried out through observation, interviews from competent sources in their fields The imbalance between profits and benefits is one of the fundamental issues in the formulation of mashlahah for producers who are faced with pressure to maximize profits in a short time, which sometimes has the potential to sacrifice the principles of benefits caused by several factors, such as adopting strategies that are oriented towards short-term profits to meet financial targets or pressure from shareholders. As a result, the benefits are often overlooked. The imbalance between profits and benefits is an important problem for sharia-based cooperatives that lack understanding of the principles of mashlahah in Islamic business, such as avoiding riba and using a clear profit-sharing system on every transaction

This study examines Chairil Anwar's poem "Diponegoro" from the perspective of literary sociology, focusing on the analysis of the values ​​of struggle contained therein. This poem depicts the figure of Prince Diponegoro as a symbol of resistance against colonialism, which reflects the spirit of the Indonesian people's struggle during the colonial period. Through the approach of literary sociology according to Wellek and Warren. This analysis also pays attention to how Chairil Anwar uses the figure of Diponegoro to convey messages about courage, sacrifice, and steadfastness in fighting oppression. The results of the study show that the poem "Diponegoro" not only functions as an individual expression of the author, but also as a form of representation of the collective aspirations of the people who are fighting for independence. Thus, the values ​​of struggle in this poem have strong social relevance, illustrating the relationship between literary works and the social dynamics around them.

This study examines the character of Bahar in the novel "Janji" by Tere Liye, focusing on the themes of sacrifice and regret. The background of this research stems from the significance of literature in reflecting human life conflicts. The problem statement raised is how Bahar's character illustrates sacrifice and regret within his social context. The method employed is descriptive qualitative, with data collection through reading and literature review. The findings indicate that Bahar makes significant sacrifices by replacing Mas Puji's position who is detained, while also confronting the stigma of being an ex-convict. Despite experiencing regret, social support and love from Delima help him overcome feelings of inferiority and achieve intimacy. This research recommends that literary works like "Janji" can serve as a medium to understand individual psychological dynamics in a social context and as educational materials in literature studies to explore humanitarian values.

Lutung Kasarung is a folk tale from West Java that can be famous among the public. This story tells about a handsome prince named Sanghyang Guruminda who was punished by being thrown to earth for making a mistake in the form of a lutung. Sanghyang Guruminda got lost in a forest so he was named Lutung Kasarung. In Sundanese Lutung Kasarung means lost Lutung. The popularity of Lutung Kasarung makes the other two characters, namely Purbasari and Purbararang, look like side characters, in fact, these siblings characters play an important role in the development of the storyline. This research aims to analyze the intrinsic elements contained in the Lutung Kasarung folklore. The formulation of this story problem includes: How is the journey of lutung kasarung to return to its original form? How is the plot of the lutung kasarung folk story? What mandate can be taken from the folk tale of lutung kasarung?. The research methods used are qualitative methods and Library Studies. Data sources are collected through literature studies that use various literature sources, including articles, journals, and websites that discuss Lutung Kasarung folklore. The analysis used is literary theory according to Meyer Howard Abrams, which is objective theory. An objective approach looks at the work of an autonomous object. It means, literary works can stand alone without involving things that are outside the work such as politics, economy, and others. Therefore, the focus of the objective approach is the work itself. The research results in this story show loyalty and sacrifice in the character of Lutung Kasarung, the characters in this story describe honor and strong inner strength with the outside world. The recommendation from this research is the need for further study development because it is still less related to the symbolism in this folklore, as well as efforts to preserve in folklore as part of cultural identity that can educate the younger generation to still preserve the noble values of our ancestors.

Aroma Karsa is a novel with a complex storyline, which combines various characters who play the role of heroes and villains, one of which is the character Raras Prayagung who has an obsession with a plant called Puspa Karsa. What is unique about the character of Raras Prayagung is his portrayal as a dark and gray figure. The purpose of this research will focus on the representation of the character of Raras Prayagung, then the role, function and contribution of Raras Prayagung in the plot of the story and identify the values and messages that can be learned through the character of Raras Prayagung in the novel Aroma Karsa.  The method used in this research is descriptive qualitative because the data used in this research comes from words, sentences, or quotes found in the novel Aroma Karsa. The result of the research found is that Raras Prayagung is a character who has a complex characterization because it represents various things, including ambition, determination, sacrifice, and moral complexity.

The statements of Jesus on the cross represent a deeply theological aspect that must continue to be studied, understood, and applied in today’s Christian ministry. Christian ministry must not ignore the meaning of Jesus’ holy suffering as an expression of His sacrifice to redeem sinful humanity. Unfortunately, there are still some who question the authenticity of this suffering, even believing that the one who was crucified was not Jesus, but one of His disciples or another person. This perspective stands in opposition to the core teachings of the Christian faith.This study aims to narrate the peak quality of Jesus’ holy suffering through His seven last sayings on the cross. The research uses a qualitative method with a library research approach and grammatical analysis of biblical texts. Data were collected from theological literature and analyzed in light of biblical implications concerning the idea of Jesus’ suffering.The findings show that each statement of Jesus on the cross holds profound theological meaning and reflects God’s eternal plan for the redemption of human sin. A grammatical analysis of these texts strengthens the understanding that Jesus’ suffering is not only a historical event but also bears a deep spiritual significance essential for human salvation. Therefore, the teaching of Jesus’ words on the cross must become an integral part of church ministry today to strengthen the faith of believers in the truth of the Gospel.

This article explores the relationship between nationalism and Christian faith from a biblical perspective. Nationalism is often defined as loyalty to nation and state, while Christian faith centres on loyalty to God and His kingdom. In the Indonesian context, churches participated in the nationalism movement from the colonialism era until independence. Based on theological studies, the Bible provides insight that believers' primary loyalty should be to God, although they are also expected to be good citizens. This article uses a literature study method with a qualitative approach to analyse relevant biblical texts as well as related theological literature. The concept of nation in the Bible is examined from the perspective of the Old Testament, which focuses on the ethnic identity of the nation of Israel, to the New Testament, which expands the nation's identity into an inclusive community of faith. The article also highlights the ethical implications of nationalism for Christians, who should reflect the values of justice, love and sacrifice, and avoid exclusionary and xenophobic attitudes.

The purpose of writing this article is to find out that Dalihan Natolu in Batak customs, especially us as Toba Batak people and we can understand that this theology is also connected to the concept of Dalihan Natolu as a symbol of unity in Toba Batak tribal customs and we also as Indonesian people are a reflection of traditions and culture that have been known throughout the world since the time of our ancestors. However, with the entry and domination of Western religions in Indonesia, traditional and cultural values ​​began to experience a process of desacralization and were even marginalized. As a result, the identity of the Indonesian people seems to be lost in expressing their beliefs. To face this challenge, a new theological model is needed that is rooted in what exists in Indonesia, in this case the concept of Dalihan Na Tolu, namely the customs of the Batak tribe. And dalihan na tolu is a kinship system that brings society to an egalitarian status in love and sacrifice.

This article discusses Jesus Christ's sacrifice on the cross as evidence of human atonement and its relevance to believers today. From the perspective of Christian faith, this event is considered a central point in the history of salvation, demonstrating divine grace and justice. Through a search of the meaning of Christ's sacrifice, this article provides a broad understanding of the meaning of Christ's suffering for man's atonement and explains how Christ's sacrifice is concrete evidence of unconditional love and the divine will to blot out human sin. Through the analysis of the meaning of redemption worked out by Jesus Christ, which will expand the theoretical basis of the purpose of Jesus' sacrifice on the cross. This article also provides a theory of the importance of understanding Christ's sacrifice on the cross, thus becoming a reference for believers in terms of faith and belief that through Christ's sacrifice brings redemption to believers. Meanwhile, the relevance of Christ's sacrifice on the cross will also affect several aspects of the believer's life, namely in terms of faith, confession, and holy living. In writing this article, a qualitative approach method is used with a literature study method. The search for the meaning of Christ's sacrifice can be studied from several perspectives, namely the theological perspective, the moral perspective and the psychologist's perspective. From a theological perspective, Christ's sacrifice is a form of God's love for man, so He sent His Son, Jesus Christ, as a sacrifice to redeem believers. So that the work of salvation done by Jesus Christ leads to a victory for believers because they have been redeemed and freed from the power of death, and also becomes a means of improving the relationship between man and God. From a moral perspective, it can be understood that Christ's sacrifice on the cross is an example of sacrifice and an example of love for believers. Thus, this article contributes to the understanding of Christ's sacrifice on the cross as a form of human atonement, and enriches the spiritual life of believers and strengthens faith, motivates spiritual life, and clarifies the moral principles underlying the Christian life.

Love is a central theme in the Christian faith, as stated in 1 John 4:7-12. This letter confirms that love comes from God, and love is the essence of God's existence and character. This article examines in depth the concept of divine love (agape) in 1 John, which is demonstrated through the sending of Jesus Christ as an atoning sacrifice for human sins. Using a hermeneutic approach and textual analysis, this article explores how God's love enables believers to reflect the character of Christ in everyday life. Through true love, believers are called to live in harmony with others as proof of their knowledge of God. Love in this context is not only a moral act, but a spiritual transformation that signifies spiritual maturity and a life in line with God's will.

This research aims to study the story of Elisha in 1 Kings 19:19-21, which describes God's call to Elisha to replace Elijah as a prophet. Elisha's action of burning his plow and slaughtering his oxen is understood to be a symbol of total sacrifice & commitment to leave his old life behind in order to follow God's call. This research uses a literature study method using Qualitative approach, analyzing biblical texts and related literature about the prophetic call & sacrifice in the Bible. The results of the analysis reveal that Elisha's actions reflect full commitment to God's call, which involves sacrifice not only materially as well as spiritually. Apart from that, Elisa's request to say goodbye to other people indicates the importance of balance between spiritual calling & human interaction. This research concludes that God's calling requires total sacrifice & commitment, but always pays attention to obligations towards family & society. It is hoped that the research output This can enable Christians to understand how to carry out God's call with full responsibility.

Every human being will experience death, and will leave his property to his heirs. Indonesia adheres to three inheritance law systems, namely Islamic inheritance law, customary inheritance law, and western inheritance law (Burgerlijk Watboek). Customary inheritance law is a hereditary belief that regulates the distribution of wealth, both material and immaterial, to heirs. Toraja society adheres to a patrilineal system in its customary inheritance law, where inheritance rights are inherited through the male lineage. The Toraja traditional inheritance system has two main concepts, namely pa'tallang and pa'rinding. Pa'tallang Refers to the process of dividing inherited assets based on sacrifices made by the heirs during the testator's lifetime. The greater the sacrifice made, the greater the inheritance rights obtained. Meanwhile, pa'rinding is related to animal sacrifice during death ceremonies, which is also a determining factor in the distribution of inheritance. The results of the research show that adopted children who are recognized by custom can receive almost the same inheritance as their biological children, especially if the deceased person does not have biological children. In addition, biological children who do not participate in this ceremony may face serious consequences in terms of their inheritance rights, which can lead to reduced rights or even loss of inheritance rights altogether.  

This article explains the interpretation of the Qur'anic verses about the hijrah, by explaining the hijrah, the various types of hijrah, verses that discuss the hijrah, and the interpretation of the Qur'anic verses about the hijrah. Hijrah is an important theme in the Qur'an which is related to physical, spiritual and social movement from one situation to a better one in order to get closer to Allah. In the context of Islamic history, hijrah refers to the movement of the Prophet Muhammad SAW and his companions from Mecca to Medina to escape persecution and achieve religious freedom. Interpretation of hijrah verses, as in QS. Al-Baqarah: 218, QS. An-Nisa: 100, and QS. At-Taubah: 20, emphasizes the importance of steadfast faith, sacrifice and struggle in achieving Allah's approval. Hijrah is seen as a form of obedience that is highly valued by Allah, with a guarantee of great rewards for those who do it with sincere intentions. The interpretation of these verses also contains a spiritual dimension, where hijrah is defined as moving from a state of sin to the path of obedience. Thus, hijrah is not only limited to the physical aspect, but also includes changes in mental and moral attitudes to improve the quality of faith and piety.This abstract explains the concept of hijrah in the Al-Qur'an and its interpretation, covering historical, spiritual and social aspects in the life of a Muslim.    

Leadership in Islam is based on the principle of monotheism, namely the belief that humans only submit to the leadership of Allah SWT. Leadership characteristics in Islam have their own characteristics because they carry out a big mission in conveying Islamic teachings. The Qur'an comprehensively regulates various aspects of life, including the concept of an ideal leader, which aims to create peace and prosperity in society. Islam sees humans as caliphs on earth, in accordance with the provisions of the Koran. This article aims to explore the verses of the Qur'an that discuss leadership, as well as formulate the goals and characteristics that an ideal leader must have from the perspective of the Qur'an. Some of the characteristics of an ideal leader identified by the author include: First, Al-Ilm (knowledgeable), and second, Mujahid (warrior). who always fights. Third, Mutay (someone who always makes sacrifices). Fourth, a caliph has potential, and is actually able to distance himself from desires in carrying out his leadership. Fifth, Mutajarrid (someone who has full and total commitment).