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Nosocomial infections are a serious problem that often occurs in hospitals and can have a negative impact on patient safety. The role of nurses, especially in inpatient rooms, is very important in preventing these infections. Preliminary studies found 0.34% of HAIs in hospitals, 0.00% of urinary tract infections, 0.86% of Phlebitis, 0.00% of Ventilator Associated Pneumonia. The aim of this study was to determine the relationship between knowledge and behavior of nurses regarding the prevention of nosocomial infections.This type of research is quantitative research with a cross sectional approach. Data collection was carried out through questionnaires. This population is all nurses in the Inpatient Room at PKU Muhammadiyah Sukoharjo Hospital. The sample for this research was 42 respondents who were selected using the total data saturated sampling technique used, namely univariate and bivariate analysis (Spearman rho test).The results of the univariate analysis research showed that the nosocomial infection prevention process variable, nurse knowledge was in the good category at 100% and the nosocomial infection prevention process variable, nurse behavior was in the good category at 100%. The results of bivariate analysis using the Spearman's rho statistical test show that there is a p-value of 0.000, where this value is smaller than 0.05 with a coefficient value of 0.528. So it can be said that there is a relationship between knowledge and behavior of inpatient room nurses in preventing nosocomial infections at the PKU Muhammadiyah Sukoharjo hospital.In conclusion, there is a relationship between knowledge and behavior in preventing nosocomial infections at the PKU Muhammadiyah hospital. Suggestions: Increase counseling and training on preventing nosocomial infections for nurses and health workers and non-health workers at the PKU Muhammadiyah Sukoharjo Hospital.

The research conducted aims to analyze the impact of public service quality on the level of public satisfaction in Ngamprah District, particularly in the implementation of the District Integrated Administration Service System (PATEN). Using simple linear regression analysis, this study evaluates the relationship between public service quality (X) and public satisfaction (Y). Data was collected from 33 respondents through questionnaires measured using a Likert scale. The analysis results indicate that public service quality has a significant impact on public satisfaction, with a regression parameter value of 0.423 and a significance value of 0.000. The coefficient of determination, or R Square, is valued at 0.771, indicating that 77.1% of the variance in public satisfaction can be explained by the quality of public service. This study concludes that improvements in public service quality are directly associated with increases in public satisfaction. The findings highlight the importance of focusing on service aspects such as timeliness, ease of access, service model variety, accuracy, completeness, courtesy, responsibility, friendliness, and comfort to achieve higher service standards and enhance public trust.

The combination of hormone treatment and genetic liabilities in transgender women leads to a complicated situation for breast cancer growth particularly linked to BRCA1 mutations. Gender-affirming treatment relies heavily on estrogen and causes intense cell growth and differentiation in breast tissue driven by estrogen receptor mechanisms. Mutations in BRCA1 lead to weak DNA repair processes which enhance an individual's vulnerability to cancerous changes. Rodestrogens enhance the functioning of proliferative pathways like PI3K/AKT and MAPK pathways in cells with dysfunctional BRCA1. This collaborative action elevates the threats posed by benign growths such as fibroadenomas leading to invasive breast cancer. By affecting the expression of vital regulatory proteins linked to cell proliferation estrogen further compromises the genomic integrity in cells harboring BRCA1 mutations. The hormone environment influenced by exogenous estrogen therapy can shape the tumor microenvironment for better cancer progression and metastasis. Comprehending the relationship between estrogen signaling and pathways related to BRCA1 is important for identifying the enhanced risk of cancer in transgender women using hormone therapy. This detailed study aligns recent discoveries regarding genetic vulnerability and hormonal impacts with cell mechanisms to reveal a detailed insight into breast cancer progression in these individuals. The study emphasizes the necessity for custom-designed cancer screening methods and targeted treatments to help mitigate risks and support transgender care. Understanding these pathways greatly enriches our knowledge of hormone-induced carcinogenesis among those who carry certain genetic markers while also guiding the creation of personalized care for transgender women at enhanced risk of breast cancer.

The objective of this study is to determine the impact of environmental performance on the sustainability reporting of companies in Indonesia, utilizing the PROPER scale as a measurement tool. This research examines whether there is an improvement in sustainability report disclosures associated with the environmental performance assessed through the PROPER scale. The study involves companies listed on the Indonesia Stock Exchange that have published annual and sustainability reports for five consecutive years. The analytical method employed is WarpPLS, with a total of 85 observations. WarpPLS is used to identify statistical relationships between environmental performance and the intensity of sustainability reporting. The findings indicate that there is an enhancement in sustainability report disclosures when the audit committee and board of directors hold regular meetings. Companies without governance committees tend to focus more on governance improvement rather than on disclosing sustainability reports. Good environmental performance, particularly in companies with specific industry types and the presence of governance committees, enhances sustainability reporting. However, companies with strong environmental performance tend to make the audit committee and board of directors focus on other responsibilities, given that the community already understands that these companies manage their environmental impact well. This study underscores the importance of the Indonesian government's support in encouraging, facilitating, and urging companies to achieve the gold category in the PROPER scale. This not only demonstrates good environmental performance but also enhances sustainability report disclosures. This research implies that good environmental performance should be accompanied by increased transparency in sustainability reporting to truly contribute to sustainable development.    

Allergic rhinitis (AR) is an atopic disease characterized by symptoms of nasal congestion, clear rhinorrhea, sneezing, postnasal drop, and nasal pruritis. The disease affects one in six people and is associated with significant morbidity, loss of productivity, and health care costs. Historically, AR was considered a disease process in the nasal airways only, although it is not serious, allergic rhinitis should be considered as a quite serious condition because it can affect the sufferer's quality of life due to the severity of the symptoms experienced and can also cause various complications. However, the development of integrated airway theory has classified AR as a component of the systemic allergic response, with other related conditions, such as asthma and atopic dermatitis, having an underlying systemic pathology. Even though it is not serious, allergic rhinitis should be considered as a quite serious condition because it can affect the sufferer's quality of life due to the severity of the symptoms experienced and can also cause various complications. In addition to nasal symptoms, patients with AR may also experience allergic conjunctivitis, non-productive cough, Eustachian tube dysfunction, and chronic sinusitis. Once diagnosed, AR can be treated in a variety of ways, with intranasal glucocorticoids being the first line of therapy.

Language and society are very closely related, this relationship includes age and social status which mutually influence language, voice color and accent for each language speaker. Sociolect (from the words social and dialect) or social dialect is a language variation associated with a particular social group. Sociolect occurs in various groups of society according to social class, age and occupation. Language differences between upper class and lower class society, teenagers and old people, doctors and lawyers, are examples of social dialect. This research aims to describe the use of sociolectic language variations in communication between the Bugis-Makassar community, Minasa Upa Village, Rappocini District, Makassar City. The data in this research are all everyday language utterances in communication that are identified as using sociolect. Meanwhile, the data source used is the Bugis-Makassar community who live in Minasa Upa Village, Rappocini District, Makassar City. Data collection techniques include; observation techniques, recording techniques and note-taking techniques. The data analysis technique is carried out in an interpretative descriptive manner, namely data that has been collected on a device, listened to and recorded, then identified and analyzed in depth by sorting and selecting information according to the research focus, namely the various forms of sociolect in communication among the Bugis-Makassar community. Based on the results of the research, the researchers found 16 data on sociolectic language variations, especially conversations in terms of age level, nobility level, and education level, with details of 8 data variations of colloquial language, 2 data variations of slang language, and 6 data variations of vulgar language.

Background:Stunting reflects the condition of children under the age of five, due to malnutrition especially in the first 1000 days of life (HPK), children are very short for their age. In Indonesia, stunting is a major and major problem that is being faced. Toddlers are children over one year old and children under 5 years old. Objective: To determine the factors associated with stunting in toddlers in the working area of ​​the Lagari Inpatient Health Center UPTD, Nabire Regency. Method: The type of research used in this study is quantitative and the design used is observational analytic. Results: analysis test using the chi-square test p-value> 0.05, 0.82 indicates that there is no relationship between education and stunting in toddlers. Analysis test using the chi-square test p-value> 0.05, namely 0.09 indicates that there is no relationship between work and stunting in toddlers. Analysis test using the chi-square test p-value <0.05, namely 0.04 indicates that there is a relationship between income and stunting in toddlers. Analysis test using chi-square test p-value <0.05, which is 0.05 indicates that there is a relationship between knowledge and the incidence of stunting in toddlers. Analysis test using chi-square test p-value <0.05, which is 0.05 indicates that there is a relationship between exclusive breastfeeding and the incidence of stunting in toddlers. Conclusion: Factors that influence stunting in toddlers include: education, employment, income, knowledge and exclusive breastfeeding. There is no relationship between education and employment with the incidence of stunting in toddlers, and there is a relationship between employment, knowledge and exclusive breastfeeding with the incidence of stunting in toddlers. Suggestion: Create a program on stunting, especially the factors that influence stunting to reduce stunting rates and need to increase counseling activities on stunting for mothers of toddlers to increase awareness and understanding of stunting.  

This qualitative literature review explores "Dynamic Workload Adjustment in Condition-Based Maintenance: A Review of Robust Optimization Approaches for Production Systems." The study synthesizes recent advancements in condition-based maintenance (CBM) frameworks, focusing on the application of robust optimization techniques to enhance production efficiency and maintenance decision-making. The review highlights the importance of dynamic workload adjustment as a crucial strategy for aligning maintenance activities with fluctuating production demands, ultimately aiming to minimize downtime and optimize resource utilization. By analyzing eight key studies in the field, this review identifies the strengths and challenges associated with the implementation of robust optimization models in CBM practices. Key findings indicate that while robust optimization significantly improves maintenance outcomes, challenges remain in terms of complexity, required skill sets, and organizational culture. The review concludes by emphasizing the need for further empirical research and the exploration of hybrid models to fully realize the benefits of dynamic workload adjustment in diverse industrial contexts. This study provides a comprehensive overview that will aid researchers and practitioners in understanding and advancing condition-based maintenance methodologies.

Approximately 5-10% of children worldwide experience impaired motor development. Disrupted child development will contribute to morbidity that occurs throughout the child's life cycle, the transmission of poverty between generations, and in the long term can hold back the pace of a country's development. The purpose of this study was to determine the factors associated with motor development in toddlers aged 2-3 years at the Nagaswidak Health Center, Palembang. The research design used observational analytic with a cross-sectional approach. The population was all mothers who had toddlers aged 2-3 years in the Nagaswidak Health Center working area in January - March 2024, totaling 32 people. Sampling used the total population technique . Data analysis used the Spearman rank test. The results of the study obtained a relationship between knowledge and gross motor development (p value 0.080) and fine motor (p value 0.135), a relationship between gender and gross motor development (p value 0.144) and fine motor (p value 0.135), a relationship between nutritional status and gross motor development (p value 0.000) and fine motor (p value 0.003). There is a relationship between nutritional status and motor development, there is no relationship between knowledge and gender and motor development. It is expected that all related parties will increase stimulation for children related to motor development.

The objective of this study is to determine the impact of environmental performance on the sustainability reporting of companies in Indonesia, utilizing the PROPER scale as a measurement tool. This research examines whether there is an improvement in sustainability report disclosures associated with the environmental performance assessed through the PROPER scale. The study involves companies listed on the Indonesia Stock Exchange that have published annual and sustainability reports for five consecutive years. The analytical method employed is WarpPLS, with a total of 85 observations. WarpPLS is used to identify statistical relationships between environmental performance and the intensity of sustainability reporting. The findings indicate that there is an enhancement in sustainability report disclosures when the audit committee and board of directors hold regular meetings. Companies without governance committees tend to focus more on governance improvement rather than on disclosing sustainability reports. Good environmental performance, particularly in companies with specific industry types and the presence of governance committees, enhances sustainability reporting. However, companies with strong environmental performance tend to make the audit committee and board of directors focus on other responsibilities, given that the community already understands that these companies manage their environmental impact well. This study underscores the importance of the Indonesian government's support in encouraging, facilitating, and urging companies to achieve the gold category in the PROPER scale. This not only demonstrates good environmental performance but also enhances sustainability report disclosures. This research implies that good environmental performance should be accompanied by increased transparency in sustainability reporting to truly contribute to sustainable development.

Based on data from the Central Statistics Agency (BPS) for 2021, the number of couples of childbearing age (PUS) in Denpasar City ranks third with a total of 81,575. In Denpasar City, the number of active family planning (FP) participants is 63,024, while those not using contraception number 10,730, and new FP participants amount to 7,840. Choosing contraception is not an easy task for healthcare providers or related agencies, as the decision must align with the individual needs of each person. In North Denpasar, there are 21,545 PUS, with 15,854 active FP participants and 5,691 not using contraception. The relatively low number of active FP participants in Denpasar City indicates a lack of understanding of the importance of contraception within families. The main issue in Denpasar City regarding the family planning program is the insufficient use of contraceptives, as evidenced by many families having more than two children, some even reaching five. This study aims to analyse the factors affecting contraceptive use in North Denpasar. Data analysis was performed using path analysis with SPSS software. The results indicate that: 1) education level negatively affects contraceptive use in North Denpasar; 2) income level and patriarchal culture positively affect contraceptive use in North Denpasar. This implies that higher income and stronger patriarchal culture are associated with higher contraceptive use in North Denpasar; 3) education level and income negatively but not significantly affect fertility in North Denpasar, suggesting that these factors do not have a significant impact on fertility; 4) patriarchal culture and contraceptive use positively but not significantly affect fertility in North Denpasar, indicating that these factors also do not significantly impact fertility.

The many possible risks associated with laboratory work are unavoidable. This study aimed to determine and analyze hazards, risks, impacts, risk levels and occupational safety and health (OHS) controls in the physics and chemistry laboratories of the Occupational Safety and Health Center (OHS) Medan. This is a qualitative research method with phenomenological approach hazard identification using Task Risk Analysis method using AS/NZS 4360: 2004 semi-quantitative. The tolerable risk threshold in the chemistry lab was 52, priority 3 was 10, and major was 11. The only thing OHS controlled in the physics lab was the air conditioning system. The presence of SOP (work procedures), MSDS (material safety data sheet) documents, OHS signs, supervision, managerial support, and the use of PPE masks, gloves, long-hand lab coats, rubber shoes, and other safety measures were all necessary in chemistry labs. Expanding the space, adding SOP, installing ventilation are all suggested at the physics laboratorium, Adopting ANSI / AIHA Z9.5-2003 ventilation guidelines, changing or replacing processes with safer chemicals, providing OHS training, and wearing coveralls and glasses are all recommended in the chemistry laboratory.

Energy is an essential requirement for civilisation, and due to the rapid expansion of the population in Indonesia, energy consumption has also experienced a substantial rise. Hence, it is crucial to utilise and enhance the capacity of sustainable energy resources present across the archipelago, including geothermal, hydropower, wind, bioenergy (including bioethanol, biodiesel, and biomass), ocean current energy, nuclear, and solar energy. Indonesia's energy strategy is currently focused on the use of renewable energy to decrease carbon emissions. This is backed by legislation that promotes the development of renewable energy programs under the National Energy strategy. This article evaluates the regulatory factors associated with the advancement of new renewable energy and its influence on the establishment of sustainable energy infrastructure in Indonesia. This research provides a comprehensive legal analysis of the changing regulations surrounding renewable energy. It examines how these regulations affect the establishment of sustainable energy infrastructure and investigates the current legal consequences. The study aims to understand how the regulatory framework can either support or impede the progress of renewable energy development. This research offers valuable insights on the role of legislation in facilitating the shift towards sustainable energy sources in Indonesia. It also sheds light on the potential obstacles and advantages that may arise during this transition.

Behçet's disease is a multisystem inflammatory disorder that can significantly impact patients' quality of life. This study conducts a meta-analysis aimed at elucidating the effects of social anxiety on treatment outcomes for Behçet's disease through a comprehensive synthesis of existing literature. Initially, a systematic search was performed across major electronic databases to identify relevant studies published between 2014 and 2024. Out of 1,253 initially identified articles, 18 studies met the inclusion criteria, encompassing 2,487 Behçet's disease patients. The meta-analysis revealed a significant negative correlation between social anxiety levels and treatment adherence for Behçet's disease (r = -0.42, p < 0.001), which was positively associated with disease symptom severity (g = 0.58, 95% CI [0.41, 0.75]). Moderator analysis indicated that the effect of social anxiety on Behçet's treatment outcomes was more pronounced in patients with mucocutaneous manifestations (Q = 7.23, p = 0.007). Additionally, social anxiety showed a strong negative correlation with patients' quality of life in health (r = -0.53, p < 0.001), with the most substantial impact observed in the social functioning domain. Furthermore, thematic analysis of the potential mechanisms underlying the relationship between anxiety and Behçet's treatment outcomes confirmed the mediating roles of patient-doctor communication barriers, increased stigma perception, and avoidance behaviour. These findings underscore the importance of assessing and addressing social anxiety in the comprehensive management of Behçet's disease. The researchers suggest that these findings could have implications for improving patient treatment and quality of life. Finally, the study supports the integration of targeted psychological interventions into standard care protocols for Behçet's disease and emphasizes the need for a biopsychosocial approach to managing this condition. 

Thyroid gland disease is a disorder that affects the thyroid gland, which plays a vital role in regulating the body's metabolism. Common symptoms associated with thyroid disease include tremors, concentration difficulties, changes in the menstrual cycle, and neck enlargement. At RSUD Dr. RM. Djoelham, Binjai, many patients struggle to understand and diagnose this disease early due to a lack of information and specific symptoms. To address this issue, an information technology-based system is needed to help the public recognize thyroid disease symptoms and provide an early diagnosis. One effective approach for designing such a system is using Case Based Reasoning (CBR), a method based on experience that solves problems by finding similar cases from existing data. This system can process symptoms entered by users, such as dry skin, anxiety, neck enlargement, and others. Based on previous cases, the system will calculate the percentage probability of the disease, thereby providing a more accurate early diagnosis. For example, if the selected symptoms are dry skin, neck enlargement, and shortness of breath, the system can give a 42% probability of a thyroid gland disorder.

This study analyzes related to the application of mathematical concepts to the demand and supply function of MSME products in North Pelawi Village, Babalan District, Langkat Regency. The results show that there is an elasticity associated with mathematical concepts for the demand function and the supply function. Usually, because MSME products are hampered by supply chain disruptions and production. However, through recovery strategies and interventions to apply mathematical concepts in the demand and supply functions, a balance curve between the demand and supply functions is formed. Awareness to apply mathematical concepts for business actors has an important role in controlling the rate of supply of goods so that the number of goods demand can be fulfilled according to the number of desires and the prices offered can be adjusted to the prices requested by consumers. This research highlights the importance of awareness and understanding the role of business actors who are aware of the application of mathematical concepts so that regulating demand and supply can run systematically and not damage the market price offered to consumers.

This research discusses the hadith in Sahih Bukhari that narrates that one of the places of misfortune is women. Textually, this hadith is controversial as it is perceived to contain misogynistic suggestions conveyed by the Prophet Muhammad (peace be upon him). The purpose of this research is to comprehensively understand the process of transmission and the scholars' interpretation of this hadith. Additionally, this research also attempts to interpret the hadith through the contemporary Fiqh al-Hadith methodology proposed by contemporary scholars. The researcher employs a qualitative inductive method, obtaining data and information by collecting classical Islamic texts, including those that specifically explain the related hadith as well as other relevant books. These include books on hadith terminology, hadith commentaries, hadith text, and hadith narrator studies, among others. This research finds that the Sahih Bukhari hadith number 5093 is of hasan quality. This hadith also has many corroborating and supporting narrations of better grades. Meanwhile, the meaning of misfortune contained in it, according to the majority of scholars, is attributed to women temporarily and not permanently. Misfortune is associated with women when they have bad character, infertility, and other non-permanent negative traits. In the mubadalah (reciprocal) method, misfortune is not only attributed to women but also to men, as men can also experience infertility, bad character, and other non-permanent negative traits.

Stunting is a chronic nutritional problem that occurs worldwide caused by suboptimal nutritional intake from pregnancy to 24 months or 2 years of age. Stunting in childhood is associated with delays in motor development and lower intelligence levels. Symptoms shown by stunting sufferers include a child's height that is shorter than children of the same age, the child looks smaller for his age, low body weight, and delayed bone growth (Laska et al., 2024). Stunting has short-term and long-term impacts. In the short term, stunting causes depression of immune function, metabolic changes, decreased motor development, low cognitive values, and low academic values (Widjayatri et al., 2020). Meanwhile, the long-term impacts of children with stunting include, when they grow up, they will be at risk of obesity, coronary heart disease, hypertension, osteoporosis, decreased work performance, and productivity (Dekasari & Gunawan, 2024)

The integration of digital transformation into government agencies' performance management has become essential in enhancing public service delivery, efficiency, and accountability. This study focuses on implementing the Electronic System for Government Agency Performance Accountability (E-SAKIP) in Indonesia as a case study of digital transformation. The research employs a qualitative approach with a case study design to explore the effectiveness, challenges, and impact of E-SAKIP on performance management. The findings indicate that E-SAKIP has significantly improved transparency and efficiency in government operations, reducing time and costs associated with performance reporting by up to 70%. However, challenges such as inadequate infrastructure, resistance to change, and insufficient training for government employees have hindered its full potential. The study underscores the need for ongoing support, including enhanced infrastructure, continuous training, and stronger leadership to ensure successful digital transformation. These insights offer valuable recommendations for further development of E-SAKIP and similar systems in other government contexts.

This study examines the business communication strategy used by Warkop Royal and the inhibiting factors of Warkop Royal's business communication strategy. To obtain the results of this study, a qualitative descriptive research method was used, then direct interviews were conducted with various sources needed in this study. The results of this study indicate that the communication strategy used by Warkop Royal is to greet consumers with polite language, promote by word of mouth, strategic location, collaboration with local businesses, and maintain the quality of food and beverages. The inhibiting factors of Warkop Royal's business communication strategy are not yet optimal in using social media, lack of training for employees, cultural and language barriers, economic conditions, and tight competition. While the SWOT theory used by Warkop Royal is that they always greet consumers with polite language, Strategy (SO) Using formal but relaxed language. Strategy (WO) Carrying out a more inclusive and adaptive approach. Strategy (ST) Providing polite and friendly language. Strategy (WT) Developing a business approach based on a deep understanding of the local market. When associated with the AIDDA Theory, Warkop Royal's business communication strategy is very promising.