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Tintin Hariyani; Dwi Ertiana; Brivian Florentis Yustanta; Rofiul Adauwiyah; Rizki Ananda Eka

Nusantara: Jurnal Pengabdian kepada Masyarakat 2025 Pusat Riset dan Inovasi Nasional

Indonesia is prone to natural disasters because it is located at the confluence of three active tectonic plates. This condition causes high earthquake, volcano, and tsunami activity in Indonesia. Mount Kelud is the most active volcano in Indonesia with cycles that recur every 8 to 15 years. The community service method carried out is to collect data on the area, population, targets, capacity, vulnerability level, and empirical data on the 2014 eruption of Mount Kelud. Then conduct analysis, calculate estimates of health logistics needs, especially reproductive health, socialize the results of the analysis, and conduct disaster preparedness education. This activity was carried out for 6 weeks from March 12 to April 21, 2025. Based on the results of the risk assessment, the Ngancar District, Kediri Regency area has a score of frequent risk scale, severe impact scale, and priority and impact scale in the high category. To overcome the health crisis, a contingency plan is needed, especially for the reproductive health sub-cluster, which includes the preparedness of target data, existing capacity in the region, the level of vulnerability, and the estimated amount of health logistics needed to anticipate the eruption of Mount Kelud. Mount Kelud has a periodic eruption pattern in 8 to 15 years. The contingency plan for dealing with the health crisis of the eruption of Mount Kelud is very important for health service stakeholders because it can minimize the adverse impacts caused, increase rapid response, and ensure smooth coordination between related institutions in dealing with the natural disaster effectively and efficiently. It also supports disaster risk reduction efforts at the community level and strengthens the resilience of local communities.

Diyanggi Priya Romaito Pane; Alexandro Wiranto Tambe

Pemuliaan Keadilan 2025 Asosiasi Penelitian dan Pengajar Ilmu Hukum Indonesia

Technological developments in the modern era have experienced rapid growth, one of which is through the advancement of Artificial Intelligence (AI). This technology has now become an integral part of people's daily lives because it can provide convenience, efficiency, and innovation in various fields. However, behind the benefits offered, AI also carries potential risks, especially when misused. One of the most worrying forms of misuse is deepfakes, namely AI-based digital content manipulation that can convincingly imitate a person's voice, face, and movements. Deepfakes have triggered various digital crimes, such as identity forgery, the creation and distribution of non-consensual pornographic content including sexual exploitation, blackmailing, the spread of fake news (hoaxes), digital terror, fraud, and defamation. The increasingly sophisticated level of AI in manipulating data demands swift action, appropriate regulations, and effective oversight strategies from the government to anticipate its negative impacts. This research uses a normative juridical method with a statute approach and a conceptual approach. This approach allows for a comprehensive analysis of the existing legal framework, the concept of legal protection, and the urgency of establishing new regulations related to AI technology. The research findings indicate that the government needs to take a number of strategic steps, including: (1) drafting specific regulations governing the use and limitations of AI, particularly regarding deepfakes; (2) developing and implementing effective deepfake detection technology; (3) providing protection, recovery, and rehabilitation mechanisms for victims; and (4) implementing widespread public education to raise public awareness of the risks of AI misuse.

Augustinus Robin Butarbutar; Jilly Toar; Priscilia Pingkan Mamuaja

Systematic Literature Review Journal 2025 International Forum of Researchers and Lecturers

Environmental health risks, including air pollution, unsafe water, and climate-sensitive diseases, remain pressing global challenges that continue to threaten public well-being. Conventional monitoring systems are typically manual, costly, and geographically limited, making it difficult to provide timely and accurate data for intervention. This study explores how digital health technologies—specifically mobile health (mHealth), the Internet of Things (IoT), artificial intelligence (AI), and remote sensing—are applied to strengthen the monitoring and management of environmental health risks. A structured literature review was carried out by synthesizing 87 peer-reviewed articles published between 2013 and 2024, using an evaluation framework built on keyword clustering, metadata filtering, and multi-criteria scoring to assess usability, scalability, interoperability, and relevance to health outcomes. Findings show that mHealth platforms are highly accessible and user-friendly but often face limitations in integration with broader health systems. IoT and AI technologies offer strong scalability and predictive capability, particularly in real-time risk detection, though they are hindered by interoperability issues across platforms. Meanwhile, remote sensing is powerful for capturing large-scale environmental data but lacks direct connections to health-specific applications. The analysis identifies a critical gap in the integration of these technologies, emphasizing the need for cross-sector collaboration to build more robust, interoperable systems. Additionally, the findings highlight the importance of ethical considerations, validation processes, and interdisciplinary approaches to ensure sustainable and impactful implementation. Overall, this study provides not only a comparative synthesis of current practices but also a methodological roadmap to guide future digital innovations in environmental health. By bridging technological potential with practical application, it underscores the urgent need for integrated strategies that can better address the growing complexity of environmental health risks in the modern era.

Silvoni Saleh; Reny Retnaningsih

Nursing Applied Journal 2025 LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Chronic Energy Deficiency (CED) in pregnant women remains a major nutritional problem in Indonesia and contributes to various maternal and neonatal complications. CED reflects a long-term energy and macronutrient deficit, often influenced by inadequate nutritional intake and socioeconomic limitations. This study aims to analyze nutritional intake and economic status as risk factors for Chronic Energy Deficiency (CED) in pregnant women in the Patilanggio Community Health Center (Puskesmas) working area. This study used a quantitative observational design with a cross-sectional approach. The study sample consisted of 30 pregnant women selected using a total sampling technique. Data were collected through interviews using a respondent characteristics questionnaire and food recall to assess energy and protein intake, as well as Mid-Upper Arm Circumference (MUAC) measurements to determine CED status. Data analysis was conducted descriptively and cross-descriptively. The results showed that all respondents had energy and protein intakes below 90% of the Recommended Dietary Allowance (RDA) and all were categorized as CED based on the MUAC measurement. All respondents were also categorized as low economic status, reflecting a homogeneous socioeconomic condition. These findings indicate that CED in pregnant women at the study site is associated with inadequate nutritional intake and limited economic status. In conclusion, CED in pregnant women is a chronic nutritional problem influenced by nutritional and socioeconomic factors, necessitating comprehensive prevention and treatment efforts based on primary health care services.

Euis Kusumarini; Eka Selvi Handayani; Maria Yosevina Tridarmawati; Riska Wanti; Suwaibatul Aslamiyah

Jurnal Pengabdian Masyarakat Nian Tana 2025 Fakultas Ekonomi & Bisnis, Universitas Nusa Nipa

This study aims to explain attempts to build honest character in less active children and increase their interest in learning through traditional congklak or dakon games. Congklak games were chosen because they have elements of competition that require honesty, while also involving fine motor activities that can stimulate the participation of children who tend to be passive. The method used is a literature methods based on literature review and analysis of earlier research result in PAUD, TK, and SD. The finding indicate that congklak these games prove beneficial in instilling honesty values, improving simple arithmetic skills, and triggering learning motivation in less active children. The strategies applied include the preparation of clear rules, providing positive encouragement, and reflection after the game. Thus, congklak games may serve as an alternative tool for educational purposes character and academics that are fun, both at school and at home, which are relevant to the developmental needs of early childhood to elementary school.

Mundakir Mundakir; Diny Wulansari

International Journal of Health and Social Behavior 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

Compliance of healthcare and medical personnel with established procedures—particularly Enterprise Risk Management (ERM) Standard Operating Procedures (SOPs)—is crucial for ensuring patient safety, high-quality healthcare services, and the sustainable operation of hospitals. This study analyzes the influence of Organizational Support, Motivation, and the Completeness of ERM SOPs on personnel compliance at Petrokimia Gresik Driyorejo Hospital. A quantitative approach using a survey method was employed. The study population included all healthcare and medical personnel directly involved with ERM SOPs. Through purposive sampling, 85 respondents were selected. Data collection used closed-ended questionnaires tested for validity and reliability. Data were analyzed using multiple linear regression through SPSS version 25. The analysis found that Organizational Support (X1), Motivation (X2), and ERM SOP Completeness (X3) simultaneously had a statistically significant effect on Compliance (Y), with the F-test showing F_calculated > F_table and significance < 0.05. Individually, all three independent variables showed a positive and significant relationship with compliance. Among them, ERM SOP Completeness had the greatest influence, followed by Motivation and then Organizational Support. These findings emphasize that clear, comprehensive, and accessible SOPs are essential in guiding staff behavior and ensuring consistent adherence to risk management protocols. Additionally, motivated employees supported by the organization are more likely to comply with procedures and internal policies. Therefore, organizational strategies should not only focus on developing complete SOPs but also on fostering a supportive work culture and enhancing staff motivation through training, recognition, and leadership support. In conclusion, the study suggests that hospitals aiming to improve compliance with ERM procedures should adopt a holistic approach by investing in SOP development, providing consistent organizational support, and maintaining high levels of employee motivation. These efforts will contribute to better risk mitigation, service quality, and overall hospital performance.

Josep Adiyono Kardipo; Abdi Sugiarto; Cut Nuraini

International Journal of Mechanical, Electrical and Civil Engineering 2025 Asosiasi Riset Ilmu Teknik Indonesia

Land use changes in the watershed (DAS) area of Tebing Tinggi City have increased the risk of flooding and contributed to the development of slum settlements in vulnerable zones. Uncontrolled urbanization and economic pressures have driven residential expansion along riverbanks, forcing communities to live in substandard environmental conditions. This study aims to analyze the integration of watershed land use change management with slum rehabilitation strategies to enhance regional resilience against flood disasters. The research employed a mixed methods approach, combining qualitative phenomenological studies with quantitative descriptive statistical analysis. The findings indicate that collaboration among spatial planning, environmental policy, and community participation is crucial in creating a sustainable and disaster-responsive watershed management model. Strategic recommendations are centered on strengthening cross-sector coordination and implementing policies based on spatial and social data.

Siti Aisyah Siahaan; Cut Nuraini; Abdi Sugiarto

International Journal of Mechanical, Electrical and Civil Engineering 2025 Asosiasi Riset Ilmu Teknik Indonesia

Slum settlements developing around Final Disposal Sites (TPA) represent a complex phenomenon that affects the quality of the urban living environment. In Karo Regency, the proximity of the TPA to residential areas has raised various issues such as air pollution, declining sanitation quality, and limited community participation in spatial planning processes. This study aims to analyze the influence of Distance to the TPA (X1), Length of Residence (X2), Community Participation (X3), Perception of TPA Impact (X4), and Household Income (X5) on the Quality of Slum Settlements (Y). A quantitative approach was applied using a multiple linear regression model, based on primary data from 200 respondents residing in areas affected by the TPA. The analysis revealed that, simultaneously, the four independent variables (X1–X4) significantly influence settlement quality, whereas household income does not show a significant effect. Partially, Distance to the TPA and Length of Residence have negative effects, while Perception of TPA Impact has a positive effect. Interestingly, Community Participation shows a negative influence, indicating ineffective engagement in environmental management. The R² value of 0.016 suggests that the model explains only a small portion of the variation, yet the F-test significance supports the overall model's relevance. Recommendations from this study include the importance of establishing a minimum 300-meter buffer zone between the TPA and residential areas, implementing sanitary landfill methods to replace open dumping systems, forming environmentally-based community forums with advocacy strength, and conducting community-based waste management training focusing on high-risk households. Strengthening participatory approaches through integration into village and sub-district spatial planning is essential for managing environmental impacts collaboratively and sustainably.

Reflin Mangengke; Reny Retnaningsih

Jurnal Ilmu Kesehatan dan Gizi 2025 Pusat Riset dan Inovasi Nasional

Early pregnancy among adolescents remains a significant public health problem and contributes to long-term medical, psychological, and social risks. Low knowledge and preventive attitudes towards reproductive health are among the factors contributing to the high rate of early pregnancy. This study aims to analyze the effect of peer education on adolescent attitudes towards early pregnancy prevention in the Ibu Community Health Center (Puskesmas Ibu) working area of West Halmahera Regency. The study design used a quasi-experimental approach with a pretest–posttest with a control group involving 40 respondents, consisting of 20 respondents in the intervention group and 20 respondents in the control group. The research instrument was an attitude questionnaire with a Likert scale that had undergone validity and reliability testing. Analysis was performed using the Wilcoxon test and the Mann–Whitney U Test at a significance level of 0.05. The results showed a significant increase in attitudes in the intervention group after receiving peer education, while the control group showed no significant change. Comparison of score changes between the two groups also showed a significant difference. These findings indicate that peer education is effective in improving adolescent attitudes towards early pregnancy prevention. This program is recommended as a community-based intervention strategy in primary health care and schools to support adolescent pregnancy prevention efforts.

Muniroh, Fitrotul; Maliha Amin; Kamsul Kamsul; Faiza Yuniati; Intan Kumalasari

DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan 2025 International Forum of Researchers and Lecturers

Tuberculosis (TB) is a contagious illness triggered by Mycobacterium tuberculosis, with transmission influenced by not only personal behaviors but also by the physical condition of the home environment. Environmental risk factors include flooring, wall material, ceiling structure, indoor temperature, humidity levels, air ventilation, habits of opening windows, and housing density. This research aimed to explore the correlation between individual behavior and the quality of home environmental conditions with pulmonary TB incidence in the Sematang Borang Health Center’s coverage area, Palembang, in 2025. A descriptive observational design was employed, involving 91 participants from Lebung Gajah Subdistrict. The sample consisted of both confirmed pulmonary TB patients (PCR positive) and individuals without TB (PCR negative), selected through purposive sampling. Data were processed using univariate analysis to describe frequency distributions and respondent characteristics. The study found that 35.2% of respondents were diagnosed with pulmonary TB, while 64.8% were not. Most participants were between 46 and 65 years old (42.9%), predominantly female (59.3%), and had a senior high school education (40.7%). In terms of TB-related knowledge and behavior, 59.3% had good knowledge, 63.7% held a positive attitude, and 50.5% practiced proper prevention measures. Nevertheless, more than half (56.0%) of the housing conditions failed to meet health standards for a safe home environment. These findings highlight that while the community shows generally good awareness and preventive behavior regarding TB, many still reside in environments that may contribute to TB transmission. Therefore, continuous health education, proactive contact tracing, and targeted health campaigns for at-risk groups—especially among those with lower educational backgrounds—should be prioritized.

Sudana Fatahillah Pasaribu; Farhatun Nurha; Dhea Syafitri; Dwitri Amalia Susanti; Etika Lase +3 more

Journal of Health Sciences, Nursing and Nutrition 2025 International Forum of Researchers and Lecturers

The nutritional status of elementary school children serves as a vital indicator of their overall growth, development, and future health outcomes. Poor nutritional status, whether in the form of undernutrition or overweight, can lead to a range of health and academic performance issues. This study aimed to assess the nutritional status of Grade 4A students at SD 064981 Cempaka Raya using anthropometric measurements and to examine the association between snacking habits and nutritional categories. A descriptive quantitative research design was employed, utilizing a total sampling approach involving all 20 students in the class. Data collection consisted of direct height and weight measurements conducted according to standardized procedures. The data were then analyzed using the WHO Anthro Plus software to classify nutritional status into undernourished, normal, overweight, and obese categories. Additionally, information on students’ snacking habits during school hours was obtained through structured questionnaires. The results indicated that 25% of students were undernourished, 50% had normal nutritional status, 20% were overweight, and 5% were obese. Bivariate analysis using the Chi-Square test demonstrated a statistically significant relationship (p < 0.001) between snacking behavior and nutritional status. Specifically, all students who reported frequent consumption of snacks at school were classified as overweight or obese, whereas those who did not engage in frequent snacking predominantly fell within the undernourished or normal categories. These findings highlight the potential role of unhealthy snacking patterns in contributing to excessive weight gain among school-age children. Based on the results, it is recommended that nutrition education programs be implemented for both students and parents, coupled with stricter regulations on the availability and sale of high-calorie snack foods within the school environment. Such measures may serve as preventive strategies to promote healthy growth, maintain optimal nutritional status, and reduce the risk of non-communicable diseases later in life.

Nafis Sururi; Fendy Bayu Firmansyah; Danang Satya Nugraha; Zamilu Toniatul Mina; Muh Fahrizal A

Jurnal Pengabdian dan Keberlanjutan Masyarakat 2025 Lembaga Pengembangan Kinerja Dosen

This community service activity was motivated by the need for an efficient and structured library management system at MI Hidayatul Ulum. Previously, book recording, borrowing, and reporting were done manually, creating administrative challenges and limiting access to information for students and teachers. To address these challenges, the community service team implemented a web-based library information system designed to simplify collection management, facilitate book searches, and expedite the borrowing and return process. The implementation method included partner needs analysis, system design and installation, training for staff and teachers, and evaluation of implementation results. The system was designed to be accessible through the school's local network with a simple and user-friendly interface. Training was provided to ensure the school was able to utilize and manage the system independently. The results showed that the implementation of this information system improved library management efficiency and expanded user access to information. Teachers could more easily monitor book collections, while students found it easier to search for and borrow books. Furthermore, the system accelerated administrative processes and reduced the risk of recording errors. Another positive impact was the growth of a technology-based literacy culture within the madrasah. With the availability of faster book search and borrowing services, students' interest in reading increased. A participatory approach involving schools from the planning stage through evaluation ensures that the resulting solutions meet needs and can be implemented sustainably. This community service activity is expected to serve as a model for implementing simple technology that has a real impact on improving the quality of basic education services.

Harnanik Nawangsari; Raudhatul Munawarah; Rosita Syaripah

Journal of Health Sciences, Nursing and Nutrition 2025 International Forum of Researchers and Lecturers

Preeclampsia is a severe pregnancy complication characterized by hypertension and signs of organ damage, with a multifactorial etiology involving maternal, genetic, and environmental interactions. This study aims to analyze determinants contributing to the occurrence of preeclampsia through a comprehensive literature review. The research method involved an in-depth analysis of 15 scientific journals, consisting of 8 national publications from Google Scholar and 7 international publications from PubMed, selected based on relevance, credibility, and publication date. Data from these sources were synthesized to identify common risk factors, biological mechanisms, and preventive measures. The findings indicate that the primary risk factors for preeclampsia include a history of chronic hypertension, obesity, gestational diabetes, nulliparity (first pregnancy), and a family history of preeclampsia. Nutritional deficiencies, particularly low calcium and vitamin D intake, are also significantly associated with increased risk. Furthermore, immunological factors such as abnormal maternal immune tolerance, as well as placental dysfunction leading to poor perfusion, play a crucial role in the pathogenesis of preeclampsia. The interplay between these factors suggests that preeclampsia is not caused by a single mechanism, but rather by a complex network of physiological, metabolic, and genetic influences. This complexity underscores the importance of early risk factor identification and intervention strategies during antenatal care. Preventive efforts may include nutritional supplementation, weight management, blood pressure monitoring, and targeted medical interventions for high-risk individuals. In conclusion, preeclampsia remains a significant contributor to maternal and perinatal morbidity and mortality worldwide. Understanding its determinants enables healthcare providers to implement timely preventive measures and reduce its negative impacts on both mother and fetus. Further research is warranted to elucidate the precise mechanisms underlying these determinants, potentially paving the way for more effective prevention and treatment strategies.

Usi Lanita

International Journal of Health and Medicine 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

Stunting is a chronic nutritional problem in toddlers that remains a global concern, including in Indonesia. This condition is characterized by height that is not appropriate for age due to long-term malnutrition, repeated infections, and environmental and social factors. The impact of stunting not only affects physical growth but also cognitive development, future productivity, and increases the risk of degenerative diseases in adulthood. Various factors contribute to stunting, including biological factors such as the child's gender and behavioral factors such as maternal knowledge about nutrition and health. This study aims to analyze the relationship between child gender and maternal knowledge and the incidence of stunting in toddlers. The research design used a quantitative cross-sectional approach. A sample of 73 respondents was selected using a stratified proportional sampling technique. Data collection was conducted through structured interviews using questionnaires and anthropometric measurements of toddlers. Data analysis was performed using univariate analysis to describe frequency distributions, and bivariate analysis using the chi-square test with a 95% confidence level. The results showed no significant association between child gender and stunting (p > 0.05). This indicates that biological factors such as gender are not the primary determinant of stunting in the study area. Conversely, there was a significant relationship between maternal knowledge and the incidence of stunting in toddlers (p < 0.05), indicating that mothers with low levels of knowledge are at greater risk of having stunted children. These findings emphasize the importance of improving maternal knowledge through ongoing nutrition education programs, health counseling, and promotive-preventive activities at community health centers. These interventions are expected to prevent stunting and other health problems in toddlers and support the achievement of the national stunting reduction target.

Nilot Pramudita; Nailla Rafa; Panji Utomo; Kukuh Hussein; Ken Ayu

Jurnal Penelitian Komunikasi dan Sosialisasi 2025 Asosiasi Peneliti dan Pengajar Ilmu Sosial Indonesia

The use of social media has become an inseparable part of daily life for Indonesian teenagers. Platforms such as Instagram, TikTok, and WhatsApp are widely used for communication, self-expression, entertainment, and information. However, behind these benefits lie significant negative impacts, particularly the rise of juvenile delinquency and digital violence. Phenomena such as cyberbullying, the spread of negative content, hoaxes, hate speech, and online exploitation are increasingly prevalent. Data from GoodStats and the 2024 National Survey on the Life Experiences of Children and Adolescents (SNPHAR) reveal high rates of violence experienced and perpetrated by teenagers in digital spaces. Furthermore, reports from the Indonesian Child Protection Commission (KPAI) show a yearly increase in cases of juvenile misbehavior linked to social media usage. This study employs a descriptive quantitative approach using secondary data from KPAI, GoodStats, and SNPHAR. The objective is to identify various forms of juvenile delinquency triggered by social media use and to explore both existing and potential strategies for prevention. The analysis indicates that low levels of digital literacy among teenagers, weak parental supervision, and the influence of social media algorithms that often amplify extreme content are major contributing factors to deviant behavior. This research emphasizes the importance of collaborative efforts among families, schools, the government, and digital platforms to create a safe and healthy digital environment for teenagers. Comprehensive digital literacy education, character development, stronger child protection regulations on the internet, and increased parental involvement are key strategies that need to be strengthened. Through an integrated approach, it is hoped that the risks of delinquency and digital violence can be minimized, enabling Indonesian youth to grow into a generation that is intelligent, critical, and responsible in their use of social media.

Hotman DS; M. Irsan Nasution

Prosiding Seminar Nasional Ilmu Ekonomi dan Akuntansi 2025 Asosiasi Riset Ekonomi dan Akuntansi Indonesia

This study aims to analyze the influence of the lifestyle of credit relationship managers (RMs) and the potential for fraud on the occurrence of non-performing loans in the banking sector. Relationship managers are the spearheads of credit distribution, interacting directly with customers, so their behavior, lifestyle, and integrity have a significant impact on the quality of a bank's credit portfolio. This study uses a qualitative descriptive method with a systematic literature review approach, reviewing various recent studies related to bank employee lifestyles, factors driving fraud, and their correlation with non-performing loans. The results indicate that a consumptive lifestyle disproportionate to income can increase the risk of fraudulent behavior, such as manipulation of credit analysis or collusion with customers, which ultimately results in an increase in non-performing loans. Furthermore, weak internal control systems, pressure to achieve credit targets, and moral hazard exacerbate this risk. A lifestyle that prioritizes social symbols and self-image can also encourage employees to engage in deviant behavior to maintain this lifestyle. Several studies have shown that RMs trapped in a hedonistic lifestyle are more vulnerable to conflicts of interest and violations of professional ethics. Meanwhile, the potential for fraud in banking practices is also influenced by employees' weak personal financial literacy, as well as limited training in risk management and ongoing work ethics. In an organizational context, a work culture oriented toward achieving targets without regard for the quality of credit analysis has the potential to create a work climate that is permissive of irregularities. This study recommends strengthening a culture of integrity through the establishment of a firm code of ethics, technology-based supervision (such as an AI-based fraud detection system), and regular training on a healthy financial lifestyle and risk management for RMs.

Balqis Khansa Rahmatillah; Anisa Humaira Pelupessy; Amelia Putri; Aisril Eka Pertiwi; Afiq Rabbani Majid +1 more

Jurnal Riset Rumpun Matematika dan Ilmu Pengetahuan Alam 2025 Pusat riset dan Inovasi Nasional

Inflammation is the body's natural biological response to tissue injury, infection, or other harmful stimuli. Inflammatory processes play an important role in maintaining the body's homeostasis, but excessive or chronic inflammation can trigger various degenerative diseases, including arthritis, cancer, and cardiovascular disorders. One of the main mediators of inflammation is the enzyme cyclooxygenase-2 (COX-2), which is in charge of converting arachidonic acid into pro-inflammatory prostaglandins. Inhibition of COX-2 activity is an important strategy in controlling inflammation. Selective COX-2 inhibitors (Coxibs) have been developed to reduce the gastrointestinal side effects commonly caused by conventional nonsteroidal anti-inflammatory drugs (OAINS). However, the use of Coxibs still poses a significant cardiovascular risk, so the search for alternatives from natural ingredients continues. Flavonoid compounds, which are abundant in fruits, vegetables, teas, and spices, show great potential as natural COX-2 inhibitors. Flavonoids have a polyphenol structure that allows for strong interactions with COX-2 active sites through hydrogen bonding and hydrophobic forces. This study is a literature review that examines the potential of flavonoids from natural ingredients as COX-2 inhibitors based on an in silico approach. This method was carried out through a literature search on the Google Scholar database using the keywords "Flavonoid", "COX-2", "In Silico", "Molecular Docking", and "Anti-inflammatory". The results of the analysis of ten articles showed that compounds such as myricetin, quercetin, rutin, catechin, and epicatechin-3-O-gallate have a high bonding affinity with COX-2, even exceeding in some cases standard drugs such as diclofenac and dexamethasone. Low bond energy values (ΔG) and optimal amount of hydrogen bonds support this potential. The findings indicate that flavonoids from natural ingredients can be developed into candidates for selective anti-inflammatory drugs COX-2 that are safer and more effective than existing synthetic therapies.

Shafa Salsabila; Yuztitya Asmaranti

Jurnal Ekonomi dan Keuangan Islam 2025 Asosiasi Riset Ekonomi dan Akuntansi Indonesia

Financial statement restatements often negatively impact investor perceptions and a company's market value. Previous studies have shown that companies conducting restatements experience significant share price declines, with an average decline of 20% following the announcement. This phenomenon reflects investors' high sensitivity to negative information related to the reliability of financial statements and suggests that a company's reputation can be damaged quickly. Financial statement restatements are generally associated with material errors or manipulation of financial information, and are therefore often linked to indications of fraud or deception in prior financial reporting. This study aims to analyze the factors influencing financial statement restatements and their impact on firm value, focusing on infrastructure companies listed on the Indonesia Stock Exchange (IDX) from 2021 to 2023. The research method used is a quantitative approach with secondary data obtained from financial statements and official company publications. The analysis was conducted using logistic regression to examine the influence of fraud factors (pressure, opportunity, and rationalization) on restatements, and linear regression to assess the impact of restatements on firm value. The results of the study indicate that of the three main factors of fraud, only rationalization significantly influences financial statement restatements. Meanwhile, pressure and opportunity do not show significant effects. Furthermore, financial statement restatements were not shown to significantly impact the value of companies in the infrastructure sector during the study period. These findings provide important insights for stakeholders in understanding financial reporting risks and the urgency of strengthening ethics and internal controls in companies.

Najwa Belvana Dofanov

VitaMedica : Jurnal Rumpun Kesehatan Umum 2025 STIKES Columbia Asia Medan

Adolescence is a crucial phase in shaping behavior and knowledge, including regarding nutritious food selection. The increased use of social media among adolescents provides opportunities for delivering nutrition education, but also carries risks associated with exposure to misleading information, including inaccurate nutrition claims. This study aims to analyze the relationship between exposure to nutrition education on social media and adolescents' awareness of food products with nutrition claims. The method used in this study was quantitative with an associative study design. The study sample consisted of 302 respondents, students from the Faculty of Public Health and the Faculty of Economics and Business, Airlangga University, class of 2022. Data collection was conducted online through a Google Form questionnaire, which included respondent characteristics and measured perceptions in shaping behavior related to exposure to nutrition education on social media and awareness of nutrition claims on food products. Data analysis was performed using Kendall's tau-b test to measure the relationship between variables. The results showed that TikTok was the most widely used social media platform by respondents, and there was a significant relationship between exposure to nutrition education on social media and adolescents' awareness of food products with nutrition claims (p < 0.01). Respondents who were more frequently exposed to educational content tended to have a better understanding and were able to respond more critically to nutrition claims. These findings emphasize the importance of utilizing social media as an effective nutrition intervention tool, particularly for adolescents who are active social media users, to increase their awareness of the importance of choosing nutritious foods. These results indicate the importance of optimizing social media as an effective nutrition intervention tool, especially for adolescents as a group of active social media users.

Hakim Tobroni HR; Berna Detha Meilyana

DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan 2025 International Forum of Researchers and Lecturers

Background : Self-management of hyperglycemia refers to a series of efforts carried out independently by individuals suffering from diabetes or hyperglycemia to manage and control their health condition. These efforts include regulating diet, physical activity, medication adherence, blood glucose monitoring, and preventive measures to avoid complications. Such complications may include vascular issues like heart disease and stroke, as well as neuropathic problems such as nerve damage. Proper implementation of self-management practices can help stabilize blood glucose levels and significantly improve the overall quality of life for patients. General Objective : This study aims to examine the effect of self-management on the risk of complications in patients with hyperglycemia in the working area of the Kandangan Health Center, Kediri Regency.Research Method : This research utilized a quasi-experimental design with a one-group pretest-posttest approach accompanied by a control group. The sampling technique applied was probability sampling using simple random sampling, involving a total of 45 respondents. The research instruments included the Diabetes Self-Management Questionnaire (DSMQ) and observation sheets to assess the risk of complications. The study population consisted of all hyperglycemic patients residing in Putuk Hamlet, Banaran Village, Kandangan District, Kediri Regency. Data processing was carried out through editing, coding, and tabulation, followed by data analysis using the Wilcoxon statistical test. Results : The Wilcoxon test results showed a significance value of p = 0.000 (p < 0.05), indicating a significant effect of self-management on reducing the risk of complications in hyperglycemic patients. Therefore, the alternative hypothesis (H1) was accepted. Recommendation : The implementation of self-management in hyperglycemic patients is essential to prevent long-term complications. Thus, healthcare professionals, especially nurses, are encouraged to provide continuous education regarding diabetes self-management. This will enable patients to manage their health conditions independently and reduce the risk of further complications.