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Najwa Amalia Putri; Haqqelni Nur Rosyidah; Didi Yunaspi

Antigen : Jurnal Kesehatan Masyarakat dan Ilmu Gizi 2026 LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Hypertension is a non-communicable disease that is still a major health problem in Batam City. This study aims to determine the relationship between energy, carbohydrate, fat, protein, and sodium intake with the incidence of hypertension in the elderly at the Sei Langkai Public Health Center, Batam City. This type of study is observational with a cross-sectional design. A sample of 73 elderly people was selected using a purposive sampling technique based on predetermined inclusion and exclusion criteria. The results showed that the majority of elderly participants had adequate energy intake (54.8%) and carbohydrate intake (57.5%), while inadequate intake was observed for fat (56.2%), protein (52.1%), and sodium (79.5%). In addition, 54.8% of the participants were found to have hypertension. Statistical analysis revealed significant associations between energy intake (p=0.020), carbohydrate intake (p=0.004), fat intake (p=0.009), and protein intake (p=0.015) and the incidence of hypertension among the elderly. However, no significant association was found between sodium intake (p=0.300) and the incidence of hypertension among the elderly. It can be concluded that energy, carbohydrate, fat, and protein intake were significantly associated with the incidence of hypertension among the elderly, whereas sodium intake was not. The elderly are advised to implement a healthy and balanced dietary intake.

Linda Fajarwati; Muhammad Irfan Hilmi; Deditiani Tri Indrianti; Sylva Alkornia

The development of digital technology has brought major changes to people's lives, including in the fields of education, economics, and social life. However, many people are still unable to utilize digital technology optimally, especially communities in remote areas. This study aims to analyze the role of out-of-school education as a solution for community empowerment in the digital era. This study uses a qualitative approach. While this type of research uses case studies. Case studies are empirical methods that investigate contemporary phenomena in real-life contexts, especially when the boundaries between phenomena and contexts are unclear. The results of the study indicate that out-of-school education has a strategic role in improving people's digital skills through technology-based training, courses, and empowerment programs. Out-of-school education is also able to improve the quality of human resources, expand digital economic opportunities, and reduce the digital divide in society. Thus, out-of-school education is a relevant and flexible educational alternative in facing the challenges of the digital era.

Nuraini Nuraini; Zahra Atiah; Azizah Hanum OK

Jurnal Pendidikan Anak Usia Dini dan Kewarganegaraan 2026 Asosiasi Riset Ilmu Pendidikan Indonesia

For every child to receive an equal education, inclusive education at the early childhood education (PAUD) level is a strategic step. The purpose of this study is to thoroughly study the basic concepts of inclusive education in early childhood, identify various types of specific challenges for Children with Special Needs (ABK) in regular classes, and evaluate how effective the use of inclusive learning methods is in optimizing child development. This study uses a literature review with a descriptive qualitative approach. Secondary data were analyzed using content analysis. According to the study, teachers in regular classes face multidimensional characteristics of ABK. These obstacles include visual impairment, deafness, mental retardation, physical disability, emotional retardation/ADHD, autism, and exceptional intelligence. To overcome these problems, it has been proven that the use of assistive technology, a more flexible curriculum, individualized learning programs (IPC) based on initial assessment, varied teaching methods, and a friendly environment can be helpful. This study shows that teachers are not the only key to the success of inclusive education. This requires strong multi-stakeholder collaboration between the government, schools, special education teachers (GPK), professionals, and parents to address facility challenges and eliminate existing stigma in the field.

Siti Rahma; Syamzaimar Syamzaimar

Jurnal Pendidikan Pancasila dan Kewarganegaraan 2026 Asosiasi Periset Bahasa Sastra Indonesia

This research used a qualitative approach with a descriptive analytical research type through a literature study method. The research data were obtained from various written sources such as scientific journals, books, research articles, and other documents relevant to the research topic. Data collection techniques were carried out through documentation by reading, recording, and classifying data according to the focus of the research. Data analysis was conducted descriptively and qualitatively through the stages of data reduction, data presentation, and drawing conclusions. The results of the study indicate that Civic Education has an important role in instilling tolerance values in students through materials related to diversity, democracy, human rights, and Pancasila values. Civic Education learning helps students understand the importance of respecting differences in ethnicity, religion, culture, and opinions in everyday life. In addition, teachers also play an important role in fostering tolerance through group discussions, teamwork, and presentation activities that train students to respect and cooperate with one another. However, there are still obstacles in implementing tolerant attitudes, such as environmental influences and the lack of awareness among some students. Therefore, cooperation between teachers, schools, and parents is needed to continuously foster students’ attitudes of tolerance.

Amal Bahrum Penas; Cut Meurah Yeni; Yusra Septivera; Cut Rika Maharani; Fara Julyta Aliyah

Jurnal Riset Rumpun Ilmu Kedokteran 2026 Pusat riset dan Inovasi Nasional

Bariatric surgery is effective in treating obesity and type 2 diabetes mellitus (T2DM); however, pregnancy occurring within 12–24 months after surgery carries significant risks. This report presents a complex pregnancy case in a patient with a history of sleeve gastrectomy, post-hemithyroidectomy hypothyroidism, and T2DM. A 29-year-old primigravida conceived 2 months after undergoing sleeve gastrectomy, which successfully induced T2DM remission, with HbA1c decreasing from 11% to 5.5%. Although glycemic control and euthyroid status were maintained throughout pregnancy, the patient developed severe preeclampsia at 35–36 weeks of gestation, complicated by intrauterine growth restriction (IUGR) and oligohydramnios. An emergency cesarean section delivered a male infant weighing 2000 grams with Apgar scores of 8 and 9 at the first and fifth minutes, respectively. The neonate required 14 days of NICU care due to respiratory distress syndrome, respiratory failure, and hyperbilirubinemia. Maternal gestational weight gain was suboptimal at only 4 kg, below the recommended range for pregnant women with obesity. This case highlights the importance of adhering to the recommended surgery-to-conception interval following bariatric surgery. Early pregnancy after surgery, combined with multiple metabolic comorbidities, may contribute to adverse maternal and neonatal outcomes. Multidisciplinary management, comprehensive nutritional monitoring, and optimization of comorbidities before conception are essential to improve pregnancy outcomes in this population.

Mohammad Ilyas Yunus; Dewi Shinta Achmad; Indri Afriani Yasin; Tusaban Tusaban

Student Scientific Creativity Journal 2026 Pusat Riset dan Inovasi Nasional

Nile tilapia (Oreochromis niloticus) culture requires an efficient and low-cost feeding strategy that can support fry growth and survival. This study aimed to analyze the effects of three types of natural feed, namely silk worms, earthworms, and snails, on absolute length growth, absolute weight growth, and survival of Nile tilapia fry. The study was conducted at the Aquaculture Laboratory, Faculty of Science and Computer Science, Universitas Muhammadiyah Gorontalo, from January 31 to March 2, 2026. An experimental method was applied using a Completely Randomized Design consisting of three treatments and three replications. A total of 45 Nile tilapia fry were reared in 9 plastic containers filled with 10 L of water, with 5 fish in each container. Growth and survival data were analyzed using ANOVA at the 5% significance level, while water quality was analyzed descriptively. The results showed that the type of natural feed had no significant effect on absolute length growth, absolute weight growth, and survival. Descriptively, silk worms produced the highest length and weight growth, with values of 2.99 cm and 6.37 g, respectively. Snails produced the highest survival rate of 86.66%. Water quality remained stable, with temperature ranging from 26.3 to 26.8°C, pH from 7.6 to 7.9, and dissolved oxygen from 5.2 to 5.6 mg/L. These findings indicate that silk worms are potential natural feed for improving growth, while snails support the survival of Nile tilapia fry.

Adam Azmi Fauzi

Jurnal Ekonomi dan Pembangunan Indonesia 2026 Asosiasi Riset Ekonomi dan Akuntansi Indonesia

This study aims to analyze the effect of profitability, company size, and type of public accounting firm on Key Audit Matters (KAM), with audit fees as a moderating variable in manufacturing sector companies listed on the Indonesia Stock Exchange for the 2022–2024 period. This study used a quantitative approach with a purposive sampling method. Data were obtained from audited financial statements and annual reports published on the official Indonesia Stock Exchange website. The study sample consisted of 67 companies, with a total of 201 observations. Data analysis techniques used included descriptive statistical analysis, classical assumption tests, multiple linear regression, and Moderated Regression Analysis (MRA). The results showed that profitability had a significant negative effect on KAM disclosure, while company size had a significant positive effect on KAM disclosure. The type of public accounting firm showed a significant negative effect on KAM disclosure. Furthermore, audit fees did not moderate the relationship between profitability and KAM, but they did moderate the relationship between company size and type of public accounting firm on KAM disclosure. This study demonstrates that company and auditor characteristics play a significant role in determining the disclosure of Key Audit Matters in the independent auditor's report.

Ahmad Akmal Muhyiddin; Tommy Trides; Shalaho Dina Devi; Revia Oktaviani; Albertus Juvensius Pontus

Globe: Publikasi Ilmu Teknik, Teknologi Kebumian, Ilmu Perkapalan 2026 Asosiasi Riset Ilmu Teknik Indonesia

This study aims to determine the soil classification of rock disintegration products based on the Unified Soil Classification System (USCS) and analyze its relation to sample depth variations on the lowwall slope of Pit North, PT Karya Putra Borneo, Kutai Kartanegara Regency, East Kalimantan. Soil samples were obtained through the Slake Durability test, simulating rock weathering from wetting and drying cycles, producing fine particles classified as weathered soil. These samples were analyzed for physical properties using Atterberg Limits tests and Grain Size Analysis. Observation point coordinates were X 508523.011 m, Y 9922791.186 m, at an elevation of 87.548 m. Drilling indicated soil material at 0–1.5 m depth; claystone with coal fragments at 2.97–4.44 m; siltstone with coal fragments at 4.44–10.55 m; and claystone at 12.05–29.36 m. USCS classification showed the materials were dominated by fine-grained soils: clay (CL) and silt (ML), with minor silty sand (SM). Correlation with borehole depth revealed no significant changes in soil classification, indicating that depth variations primarily affect soil physical properties rather than its classification type.  

Oliverensius Ngatamri; Fransiskus Erick Saputra Pantur; Fransiskus Sandriano

jurnal Riset Rumpun Agama dan Filsafat 2026 Pusat Riset dan Inovasi Nasional

The book on the City of God and the City of Man is a masterpiece by St. Augustine that is very influential in the history of philosophy and theology. This book contains the background of Augustine's philosophical and theological reflections on the accusation of the destruction of the Roman Empire against Christianity. The City of God described in Augustine's perspective is a city that prioritizes love for God. While the City of Man is a city that reflects self-love. The implications of both types of cities in Augustine's perspective are very relevant to be discussed in the discourse on the concept of statehood. This paper also aims to analyze the relationship between democracy and capitalism in the perspective of Augustine of Hippo's thought, especially through the concept of civitas Dei (City of God) and civitas terrena (World City). This study uses a qualitative method with a library research approach. The results of this study show that democracy and capitalism, although providing space for freedom, are vulnerable to deviations when not guided by the correct moral orientation. In light of Augustine's thought, the crisis in modern democracy such as; Money politics, media manipulation, and anarchic demonstrations reflect the dominance of self-love (amor sui) that characterizes the civitas terrena. Therefore, democracy can only operate fairly if it is rooted in moral values ​​that lead to the common good (Bonum communae).

Ruth Manurung; Cindy C. Nadeak; Helda H. Hia; Jesika P. Sitorus; Nurjasni Nurjasni +1 more

Publikasi Para ahli Bahasa dan Sastra Inggris 2026 Asosiasi Periset Bahasa Sastra Indonesia

This study examines the use of dysphemistic language in selected songs from Sabrina Carpenter’s Man’s Best Friend album. The research aims to identify the dysphemistic expressions found in the lyrics and to analyze how these expressions are linguistically constructed to convey emotional intensity and communicative meaning. The study applies a qualitative descriptive approach. The data consist of dysphemistic expressions collected from the selected song lyrics and classified according to the dysphemism categories proposed by Keith Allan and Kate Burridge. The analysis focuses on identifying the types of dysphemism and examining their function as a language strategy within the lyrical context. The findings indicate that dysphemistic expressions appear consistently in the lyrics and contribute to the expression of emotional tension and interpersonal conflict. These expressions also function as a stylistic device that shapes the tone and communicative impact of the songs. The study highlights the role of dysphemistic language as part of the expressive and stylistic resources used in contemporary pop music lyrics.

Nisrina Khalisha Bahij; Sri Mulyati; Risna Meliyani

DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan 2026 International Forum of Researchers and Lecturers

Therapeutic adherence is a fundamental cornerstone in managing Type 2 Diabetes Mellitus (DM) to maintain stable blood glucose levels and prevent chronic complications. Family support serves as a significant external determinant influencing the development of long-term patient adherence behaviors. This quantitative study, utilizing a correlational analytic design with a cross-sectional approach, aimed to analyze the relationship between family support and therapeutic adherence levels among Type 2 DM patients at Royal Prima Hospital, Jambi City. Through total sampling, 92 respondents were enrolled as the study sample. Data were collected via questionnaires and analyzed using the Chi-Square test. Univariate analysis revealed that the majority of respondents received moderate family support (46.7%) and demonstrated adherent behavior (62.0%). Bivariate analysis yielded a Pearson Chi-Square value of 17.186 with a p-value of 0,000 (α < 0,05), leading to the rejection of H0 and the acceptance of Ha. In conclusion, there is a statistically significant relationship between family support and therapeutic adherence levels among Type 2 DM patients at Royal Prima Hospital, Jambi City, indicating that more optimal family support is directly proportional to increased therapeutic adherence.

Afifah Tasya Kamila; Baiq Aulia Ali; Adila Rizkika; Luluk Alfhina

JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL 2026 CV. ALIM'SPUBLISHING

Drug-Related Problems (DRPs) are common in patients with type 2 Diabetes Mellitus (T2DM) who receive combination therapy involving oral antidiabetic agents and insulin. This literature review aims to identify the main types of DRPs and the factors contributing to their occurrence based on recent studies from PubMed, ScienceDirect, ResearchGate, and Google Scholar. The most frequently reported DRP is drug interaction, followed by underdosing, overdosing, therapy without indication, untreated indications, adverse drug reactions, and patient-related problems such as non-adherence. Several factors contribute to the occurrence of DRPs, including polypharmacy, inappropriate dosing, the presence of comorbidities, limited patient knowledge regarding therapy, and inadequate clinical monitoring. These conditions may increase the risk of poor glycemic control and treatment failure. Therefore, effective management of DRPs is essential to improve therapeutic outcomes. The findings of this review emphasize the important role of pharmacists in conducting medication reviews, identifying DRPs early, and implementing appropriate interventions to enhance patient safety and optimize treatment in T2DM patients.

Afifah Tasya Kamila; Baiq Aulia Ali; Adila Rizkika; Luluk Alfhina

JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL 2026 CV. ALIM'SPUBLISHING

Drug-Related Problems (DRPs) are common in patients with type 2 Diabetes Mellitus (T2DM) who receive combination therapy involving oral antidiabetic agents and insulin. This literature review aims to identify the main types of DRPs and the factors contributing to their occurrence based on recent studies from PubMed, ScienceDirect, ResearchGate, and Google Scholar. The most frequently reported DRP is drug interaction, followed by underdosing, overdosing, therapy without indication, untreated indications, adverse drug reactions, and patient-related problems such as non-adherence. Several factors contribute to the occurrence of DRPs, including polypharmacy, inappropriate dosing, the presence of comorbidities, limited patient knowledge regarding therapy, and inadequate clinical monitoring. These conditions may increase the risk of poor glycemic control and treatment failure. Therefore, effective management of DRPs is essential to improve therapeutic outcomes. The findings of this review emphasize the important role of pharmacists in conducting medication reviews, identifying DRPs early, and implementing appropriate interventions to enhance patient safety and optimize treatment in T2DM patients.

Desy H Sihombing; Yuki Tambunan; Selfius Dur; Rahel Dwi Ivana; Ronny Simatupang

jurnal Riset Rumpun Agama dan Filsafat 2026 Pusat Riset dan Inovasi Nasional

This study aims to examine the methods, models, strategies, as well as the design and development of the Christian Religious Education curriculum within the family. The research employs a qualitative approach with a descriptive type through library research, using data sources such as books, scientific journals, and relevant articles. The results of this study indicate that faith education in the family should be carried out holistically through various methods such as modeling, habituation, teaching, and mentoring. In addition, educational models such as the theocentric, relational, and participatory models provide clear direction in nurturing children’s faith. Effective strategies include modeling, dialogical communication, spiritual habituation, mentoring, and discipline based on love. Meanwhile, a simple family-based curriculum that includes objectives, materials, methods, media, and evaluation is essential to support a well-directed educational process. The success of Christian Religious Education in the family largely depends on the active role and consistency of parents in implementing methods, models, strategies, and curriculum in an integrated manner. With the right approach, the family can become an effective center of faith education in shaping children who are faithful, have strong character, and are prepared to face life’s challenges.

Salma Puspita Ramadhanti; Adiratna Sekar Siwi; Aji Kurniawan

JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL 2026 CV. ALIM'SPUBLISHING

Intracerebral Hemorrhage (ICH) is one of the types of stroke with the highest rates of mortality and morbidity. This condition is often accompanied by decreased levels of consciousness and hemodynamic instability, particularly in patients undergoing intensive care in the ICU. The application of murottal (Qur’anic recitation) therapy is expected to contribute to the stabilization of patients’ hemodynamic, physical, and physiological conditions. The purpose of this study was to explore the effect of Qur’anic murottal therapy on the hemodynamic stability of ICU patients at RSUD Prof. Dr. Margono Soekarjo Purwokerto. This study used a case study design in the form of a nursing care report involving one patient diagnosed with ICH and a nursing problem of decreased intracranial adaptive capacity. The intervention consisted of listening to the recitation of Surah Ar-Rahman for 20 minutes once per shift over three consecutive days. The observed hemodynamic parameters included blood pressure, heart rate, respiratory rate, body temperature, oxygen saturation, and the Glasgow Coma Scale (GCS). The results showed that after the administration of the murottal therapy of Surah Ar-Rahman, the patient experienced improvement and stabilization in hemodynamic parameters, including blood pressure, pulse rate, respiration, and oxygen saturation. Qur’anic murottal therapy of Surah Ar-Rahman has a positive effect on the hemodynamic stability of ICH patients in the ICU at RSUD Prof. Dr. Margono Soekarjo Purwokerto. This intervention has the potential to serve as a non-pharmacological approach to support holistic recovery and improvement in critically patients.

Annisa Ritonga; Rapotan Hasibuan; Delfriana Ayu A; Eliska, Eliska; Muhammad Zali

JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL 2026 CV. ALIM'SPUBLISHING

The intake of macro and micro nutrients is very important because the intake of these macronutrients is the main contributor to energy which is the main source for muscle growth. The purpose of this study is to determine the intake of macro and micro nutrients in the Islamic Islamic Boarding School Padang Garugur Padang Lawas Utara. This type of research is a quantitative descriptive research with the aim of creating a description or descriptive of a state of the research object. Data collection was conducted through interviews using macro and micro nutrient tester questionnaires. The questionnaire was given to students and students. The data were analyzed univariate to determine the distribution and frequency. The results of the study showed that the intake of macronutrients of students was in the protein intake of 19 respondents in the poor category, carbohydrate intake as many as 7 respondents in the poor category, and fat intake in 10 respondents in the poor category. The intake of micronutrients, namely the intake of drinking water consumed by students, was 9 respondents in the category of lack. It is recommended that students need to consume a variety of food and beverage intake that has nutritional content, in order to meet nutritional needs.

Salma Puspita Ramadhanti; Adiratna Sekar Siwi; Aji Kurniawan

JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL 2026 CV. ALIM'SPUBLISHING

Intracerebral Hemorrhage (ICH) is one of the types of stroke with the highest rates of mortality and morbidity. This condition is often accompanied by decreased levels of consciousness and hemodynamic instability, particularly in patients undergoing intensive care in the ICU. The application of murottal (Qur’anic recitation) therapy is expected to contribute to the stabilization of patients’ hemodynamic, physical, and physiological conditions. The purpose of this study was to explore the effect of Qur’anic murottal therapy on the hemodynamic stability of ICU patients at RSUD Prof. Dr. Margono Soekarjo Purwokerto. This study used a case study design in the form of a nursing care report involving one patient diagnosed with ICH and a nursing problem of decreased intracranial adaptive capacity. The intervention consisted of listening to the recitation of Surah Ar-Rahman for 20 minutes once per shift over three consecutive days. The observed hemodynamic parameters included blood pressure, heart rate, respiratory rate, body temperature, oxygen saturation, and the Glasgow Coma Scale (GCS). The results showed that after the administration of the murottal therapy of Surah Ar-Rahman, the patient experienced improvement and stabilization in hemodynamic parameters, including blood pressure, pulse rate, respiration, and oxygen saturation. Qur’anic murottal therapy of Surah Ar-Rahman has a positive effect on the hemodynamic stability of ICH patients in the ICU at RSUD Prof. Dr. Margono Soekarjo Purwokerto. This intervention has the potential to serve as a non-pharmacological approach to support holistic recovery and improvement in critically patients.

Annisa Ritonga; Rapotan Hasibuan; Delfriana Ayu A; Eliska, Eliska; Muhammad Zali

JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL 2026 CV. ALIM'SPUBLISHING

The intake of macro and micro nutrients is very important because the intake of these macronutrients is the main contributor to energy which is the main source for muscle growth. The purpose of this study is to determine the intake of macro and micro nutrients in the Islamic Islamic Boarding School Padang Garugur Padang Lawas Utara. This type of research is a quantitative descriptive research with the aim of creating a description or descriptive of a state of the research object. Data collection was conducted through interviews using macro and micro nutrient tester questionnaires. The questionnaire was given to students and students. The data were analyzed univariate to determine the distribution and frequency. The results of the study showed that the intake of macronutrients of students was in the protein intake of 19 respondents in the poor category, carbohydrate intake as many as 7 respondents in the poor category, and fat intake in 10 respondents in the poor category. The intake of micronutrients, namely the intake of drinking water consumed by students, was 9 respondents in the category of lack. It is recommended that students need to consume a variety of food and beverage intake that has nutritional content, in order to meet nutritional needs.

Nizma Hartin Ferawati; Farida Noor Irfani; Nazula Rahma Shafriani

JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL 2026 CV. ALIM'SPUBLISHING

Neonatal sepsis is a major factor contributing to morbidity and mortality in newborns. C-Reactive Protein (CRP) and leukocytes are laboratory tests used as indicators of inflammation. This study aims to determine the relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients. The research method used was an observational analytic with a cross-sectional approach. Neonatal sepsis at PKU Muhammadiyah Yogyakarta in the period 2021-2026 consisted of 30 samples using a total sampling technique. The distribution of respondents was dominated by male gender compared to female gender, who had a low birth weight <2,500 grams. Based on the study, normal CRP levels were found in 21 respondents, which was caused by a delay in increasing CRP levels. Leukocytes had high levels in 18 respondents. Leukocytes are an initial phase of examination in detecting inflammation that does not require a long time, have several different morphological types in detecting inflammation in the body. This study shows that the most dominant increase in leukocyte levels is found in eosinophils and neutrophils. Based on medical record data at PKU Muhammadiyah Hospital Yogyakarta, analysis using the Spearman correlation test yielded a correlation coefficient of 0.261 with a significance value of 0.164 (p > 0.05). The results showed no significant relationship between the studied variables, with a positive direction and weak correlation strength. The conclusion of this study is that there is no significant relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients.

Nizma Hartin Ferawati; Farida Noor Irfani; Nazula Rahma Shafriani

JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL 2026 CV. ALIM'SPUBLISHING

Neonatal sepsis is a major factor contributing to morbidity and mortality in newborns. C-Reactive Protein (CRP) and leukocytes are laboratory tests used as indicators of inflammation. This study aims to determine the relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients. The research method used was an observational analytic with a cross-sectional approach. Neonatal sepsis at PKU Muhammadiyah Yogyakarta in the period 2021-2026 consisted of 30 samples using a total sampling technique. The distribution of respondents was dominated by male gender compared to female gender, who had a low birth weight <2,500 grams. Based on the study, normal CRP levels were found in 21 respondents, which was caused by a delay in increasing CRP levels. Leukocytes had high levels in 18 respondents. Leukocytes are an initial phase of examination in detecting inflammation that does not require a long time, have several different morphological types in detecting inflammation in the body. This study shows that the most dominant increase in leukocyte levels is found in eosinophils and neutrophils. Based on medical record data at PKU Muhammadiyah Hospital Yogyakarta, analysis using the Spearman correlation test yielded a correlation coefficient of 0.261 with a significance value of 0.164 (p > 0.05). The results showed no significant relationship between the studied variables, with a positive direction and weak correlation strength. The conclusion of this study is that there is no significant relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients.