Artikel Review: Drug Related Problems pada Penggunaan Terapi Antidiabetik Oral dan Insulin pada Penderita Diabetes Mellitus Tipe 2

Afifah Tasya Kamila ; Baiq Aulia Ali ; Adila Rizkika ; Luluk Alfhina
JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL 📅 2026 Vol 4, No 2 🔗 DOI: 10.59024/jikas.v4i2.1667
Abstract
Drug-Related Problems (DRPs) are common in patients with type 2 Diabetes Mellitus (T2DM) who receive combination therapy involving oral antidiabetic agents and insulin. This literature review aims to identify the main types of DRPs and the factors contributing to their occurrence based on recent studies from PubMed, ScienceDirect, ResearchGate, and Google Scholar. The most frequently reported DRP is drug interaction, followed by underdosing, overdosing, therapy without indication, untreated indications, adverse drug reactions, and patient-related problems such as non-adherence. Several factors contribute to the occurrence of DRPs, including polypharmacy, inappropriate dosing, the presence of comorbidities, limited patient knowledge regarding therapy, and inadequate clinical monitoring. These conditions may increase the risk of poor glycemic control and treatment failure. Therefore, effective management of DRPs is essential to improve therapeutic outcomes. The findings of this review emphasize the important role of pharmacists in conducting medication reviews, identifying DRPs early, and implementing appropriate interventions to enhance patient safety and optimize treatment in T2DM patients.
Keywords
Combination Therapy; Drug-Related Problems; Insulin; Oral Antidiabetic Agents; Type 2 Diabetes Mellitus
How to Cite

Afifah Tasya Kamila, et al. (2026). Artikel Review: Drug Related Problems pada Penggunaan Terapi Antidiabetik Oral dan Insulin pada Penderita Diabetes Mellitus Tipe 2. JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL, 4(2). https://doi.org/10.59024/jikas.v4i2.1667

Afifah Tasya Kamila; Baiq Aulia Ali; Adila Rizkika; Luluk Alfhina, "Artikel Review: Drug Related Problems pada Penggunaan Terapi Antidiabetik Oral dan Insulin pada Penderita Diabetes Mellitus Tipe 2," JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL, vol. 4, no. 2, 2026.

Afifah Tasya Kamila; Baiq Aulia Ali; Adila Rizkika; Luluk Alfhina. "Artikel Review: Drug Related Problems pada Penggunaan Terapi Antidiabetik Oral dan Insulin pada Penderita Diabetes Mellitus Tipe 2." JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL, vol. 4, no. 2, 2026.

Afifah Tasya Kamila; Baiq Aulia Ali; Adila Rizkika; Luluk Alfhina. "Artikel Review: Drug Related Problems pada Penggunaan Terapi Antidiabetik Oral dan Insulin pada Penderita Diabetes Mellitus Tipe 2." JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL 4, no. 2 (2026).

Afifah Tasya Kamila, et al. (2026) 'Artikel Review: Drug Related Problems pada Penggunaan Terapi Antidiabetik Oral dan Insulin pada Penderita Diabetes Mellitus Tipe 2', JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL, 4(2). doi: 10.59024/jikas.v4i2.1667.

Afifah Tasya Kamila; Baiq Aulia Ali; Adila Rizkika; Luluk Alfhina. Artikel Review: Drug Related Problems pada Penggunaan Terapi Antidiabetik Oral dan Insulin pada Penderita Diabetes Mellitus Tipe 2. JURNAL ILMIAH KESEHATAN MASYARAKAT DAN SOSIAL. 2026;4(2).

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