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Caries is caused by microbial activity of a fermented carbohydrate. The results of Basic Health Research (RISKESDAS) state that the largest proportion of dental problems in Indonesia are damaged/cavities/sick teeth (45.3%). Preventive efforts gargling mouthwash contains antibacterial, long-term use has side effects, so we need herbal ingredients that have antibacterial properties, one of which is celery leaves. This study aims to prove the potential of celery leaf extract (Apium graveolens L.) as a mouthwash ingredient in inhibiting the growth of caries-causing bacteria and being able to reduce the number of bacterial colonies compared to formulary controls without active ingredients. This type of research used laboratory and field experiments with pretest-posttest consisting of the intervention group of celery leaf extract mouthwash formulation concentrations of 30%, 15% and control formulary without active ingredients, the sample consisted of 39 people, the sample was rinsed for 1 minute. Saliva collection before and after gargling. The variables studied the inhibition of bacteria. The results of the inhibition of Streptococcus mutans bacteria carried out by the ANOVA test at a concentration of 15% showed a mean of 5 mm and a concentration of 30% with a mean of 6.2 mm with a p-value of 0.000 which means that there was a significant difference in inhibiting Streptococcus mutans bacteria, while the control had a mean of 0. 0 mm which means there is no resistance formed. The conclusion of this study is that giving celery leaf extract mouthwash Calculate the inhibition zone with a concentration of 15%, 30% being able to inhibit bacteria while the control has no inhibition on Streptococcus mutans bacteria.

Determination of total flavonoid levels is calculated based on the linear regression equation based on the calibration curve of the quercetin standard solution from the reading results of the UV-Vis spectrophotometry tool. The absorbance value (ppm) is entered into the linear regression formula as the y value, while the x value is the concentration of flavonoids in the working sample solution. The results are stated in triplicate and the flavonoid content is stated with the equivalence of flavonoid standards using quercetin standard standards, qualitative and quantitative research methods to determine metabolite compounds and determination of levels using UV-vis spectrophotometry. Qualitative testing is carried out by taking a thick extract and adding reagents according to the identified compounds. Based on the results of the tests carried out, it shows that alkaloid, flavonoid, steroid, triterpenoid, tannin, and saponin compounds show positive results while quinone compounds show negative results. Quantitative testing From the results of this study, the total flavonoid content of the ethanol extract of itching leaves (Laportea stimulans) was 175.961%. Based on the results of qualitative tests, it shows that the ethanol extract of itchy leaves (Laportea stimulants) positively contains several compounds including alkaloids, flavonoids, steroids, terpenoids, tannins, and saponins which are indicated by changes in color. Based on the results of quantitative tests, it shows that the determination of the content of 95% ethanol extract of itchy leaves (Laportea stimulants) spectrophotometrically at a wavelength of 430 nm has an average total flavonoid content of 0.2999%.  

Body scrub is a type of cosmetic preparation that has seen increased use, particularly with the incorporation of natural ingredients as its base. Belimbing wuluh (Averrhoa bilimbi Linn.) is a traditional medicinal plant known for its high content of saponins, flavonoids, tannins, glycosides, and formic acid, all of which contribute to its significant antioxidant activity. This makes it a promising candidate for development into a cosmetic product for skin care. This study involved the formulation of body scrub preparations using A. bilimbi powder, with variations in triethanolamine (TEA) as an emulsifying and alkalizing agent to optimize the resulting product formula, which was then tested physically. The A. bilimbi fruit was processed into simplicia, which was subsequently ground and formulated into three different body scrub formulas. These three formulas were subjected to organoleptic tests, homogeneity tests, and pH tests to assess the impact of varying TEA concentrations. The results indicate that TEA influences the texture and pH values of the body scrub preparations. However, the distribution of the preparations based on the homogeneity test results showed no significant differences among the three formulas. The study identified Formula II, with a 3% TEA concentration, as the most optimal formula, meeting SNI standards for pH and demonstrating the best organoleptic properties among the three formulas.

Hydroquinone is a compound that is often used in skin whitening beauty products. According to BPOM 2007, the use of hydroquinone at levels above 2% can cause skin disorders, namely hyperpigmentation which can lead to skin cancer. This research was conducted to qualitatively analyze the hydroquinone compound found in skin whitening soap which does not have a BPOM number. The aim of this research is to determine the presence of hydroquinone compounds contained in skin whitening soap samples and to determine the differences in Rf values ​​resulting from the comparison of the concentrations of the mobile phase used. Qualitative analysis was carried out by calculating the Rf value of paper chromatography using a comparison of variations in mobile phase concentration, namely 50% ethanol: chloroform (1: 1) and 90% ethanol: chloroform (1: 1). The analysis results show that the standard Rf value of hydroquinone from the eluent of 50% ethanol and chloroform is 0.46, where this Rf value is the same as the Rf value from sample number 5, namely 0.46. Meanwhile, the Rf value using 90% ethanol and chloroform eluents in sample No. 5 is 0.67, which is not the same as the standard Rf value, namely 0.56. Of the whitening soap samples, 1 sample showed a positive result containing hydroquinone.

Pear skin contains flavonoids which have potential as antioxidants. Considering the existence of humans as social creatures, interacting with each other requires self-confidence to be well accepted. For this reason, humans need self-care to appear charming, attractive and full of self-confidence. Masks are a type of cosmetic treatment that is well known and widely used. The mask works deeply to remove dead horn cells on the skin. This research aimed to determine the potential antioxidant activity of the ethanol extract of pear peel (Pyrus bretschneideri) which was formulated as a sheet mask preparation. Extraction was carried out by maceration using 96% ethanol to obtain pear peel extract. The antioxidant activity test method was carried out using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. The results obtained from the concentration of the sheet mask preparation of pear peel extract (Phyrus bretschneideri) were homogeneous and stable. The pH results obtained from F0 (5,1), F1 (5,4), F2 (5,5), F3 (5,6), are still within the safe range of facial skin pH. The results of the antioxidant activity test showed that the IC50 value for F1 was 84.58 ppm with intensity (Strong), F2 69.96 ppm with intensity (Strong), and F3 63.79 ppm with intensity (Strong).

This study aims to determine the energy and carbohydrate content of soybean hulls soaked with husk ash water filtrate (FAAS). The study used an experimental method with a randomized complete block design (RAL) Factorial, Factor I; the concentration of husk ash water filtrate consists of F1: 10%, F2: 20% and F3: 30%. The second factor is the length of soaking time consisting of W1: 24 hours, W2: 48 hours, and W3: 30 hours. Each treatment was repeated three times. Based on the results of statistical analysis showed that there was no interaction (P<0.05) between the concentration of FAAS and the length of soaking time on the Energy and Carbohydrate values of soybean hulls. 

Concentration of learning in children is how children focus on doing or doing something until the job is done in a certain time. In some 6th grade children at Eben Haezer Family Elementary School have difficulty concentrating which causes a decrease in learning achievement due to the fact that children often play gadgets, experience low thinking levels such as memory disorders, and children have a history of illness since childhood so that teachers who also complain and are confused in improving and overcoming children who have difficulty concentrating when learning takes place. Brain gym is a collection of simple movements that aim to connect or unite the mind and body so that not only will facilitate the flow of blood and oxygen to the brain, but also movements that can stimulate the work and functioning of the brain optimally. This study was conducted to determine the effect of Brain Gym on the level of learning concentration in students at SDS Eben Haezer Family. This study is a quantitative research pre-Experimental approach one group pre-post test with a sample of 21 respondents with a total sampling technique. Analysis of the data in this study using the Wilcoxon test with the analysis test obtained the value of p value =0.000 (p<0.05) so that the conclusion of this study there is the influence of Brain Gym on the level of concentration of learning in students at SDS Eben Haezer Family.    

Coal mining activities often result in acid mine drainage (AMD), which can cause environmental pollution if not properly managed. This study aims to evaluate the potential use of fly ash from the Stream Power Plant (PLTU) Tenggarong to mitigate the impacts of AMD, specifically targeting iron (Fe), manganese (Mn), and pH parameters. Acid Mine drainage is formed when sulfide minerals oxidize, producing acidic compounds that can harm the environment. This research focuses on analyzing the ability of fly ash to adsorb iron and manganese from AMD solutions, as well its capability to increase solution pH. Based on the conducted research, the optimum pH value was achieved when using 10 grams and 15 grams of fly ash in the adsorption process. The optimum concentration of iron (Fe) was attained using 10 grams to 15 grams of fly ash, while for manganese (Mn), it was achieved with 20 grams to 25 grams of fly ash. The adsorption process using 25 grams of fly ash showed the highest efficiency in reducing iron (Fe) concentration by 93.78 % and manganese (Mn) concentration by 75.47 %.

This research develops an indoor air quality monitoring notification system for production rooms based on the Internet of Things (IoT) using the ESP8266. The system is designed to detect and provide early warnings of air pollution in production rooms. The Sharp GP2Y1010AU0F sensor is used to measure the concentration of dust particles in the air. Data from the sensor is sent to the ESP8266 module connected to the internet. This information is then forwarded to the Blynk application, enabling real-time monitoring through mobile devices. If the dust concentration exceeds the predetermined threshold, the system will activate the buzzer as an alarm. Test results show that this system can provide accurate and responsive notifications, thus helping to improve safety and health in the production environment.

An innovative and sensitive method for extracting liquid-liquid flour using pre-mixingwith the single-drop microextraction technique. This working system is distinguished by itsability to be applied to chemical and biological analyses. It is suitable for microfluidics, has ashort time, is free of contaminants, and has a simple design that can be installed anywhere inthe laboratory. The working system consists of several basic parts: a pump device to pump orfall back the organic and aqueous phase from the liquid-liquid micro-system through micro-rubber tubes and two precise micro-needles to generate drops, two mixers using two magneticclamps on two graduated holders, and a precise micro-mixer to complete the mixing process.Study of the main variables in the system containing dithizone (0.0001 M). ) in CHCl₃ solventsolution and aqueous copper chloride solution (1000 ppm) to see how they affect theextraction performance obtained by this method. The effect of the copper concentration in theinitial sample, the speed of the mixer, and the flow rate were discussed and studied, and thebest conditions were determined: for (2 ml) sample an aqueous solution of copper (II)chloride, the optimal concentration of copper. (II) in the analyzed sample is (0.0001M), thespeed of the micromixer is maximum, and the pump flow rate is (0.5 ml /sec). In theseoptimal conditions, the degree of extraction was (97±2%).

Plants have several ways to protect themselves from bacteria, one of which is by producing compounds that are toxic or repellent to bacteria. Compounds produced by plants are known as secondary metabolite compounds which originate from secondary metabolic processes. Several secondary metabolite compounds such as flavonoids, alkaloids, saponins, tannins, steroids and terpenoids are currently widely used as antibacterials. One of the plants that has the potential to be developed as a herbal medicine is kaffir lime leaves. Citrus hystrix is ​​the part of the plant most often used by the public. Both for cooking and traditional medicine purposes. In this research, it is hoped that lime peel extract can act as an antibacterial for Escherichia coli and staphylococcus aereus, so that it can be used as a herbal plant for diseases caused by these two bacteria. In the research, the concentrations used for each test bacteria were 50%; 25%; 12.5%. in observing S. aureus bacteria 1x24 hours with a concentration of 50%, the size of the inhibitory zone was 16 mm, the 25% concentration was 11 mm and the 12.5% ​​concentration was 9 mm. Meanwhile, E. Coli bacteria did not show any reaction to the heruk peel extract.

Plants have several ways to protect themselves from bacteria, one of which is by producing compounds that are toxic or repellent to bacteria. Compounds produced by plants are known as secondary metabolite compounds which originate from secondary metabolic processes. Several secondary metabolite compounds such as flavonoids, alkaloids, saponins, tannins, steroids and terpenoids are currently widely used as antibacterials. One of the plants that has the potential to be developed as a herbal medicine is kaffir lime leaves. Citrus hystrix is ​​the part of the plant most often used by the public. Both for cooking and traditional medicine purposes. In this research, it is hoped that lime peel extract can act as an antibacterial for Escherichia coli and staphylococcus aereus, so that it can be used as a herbal plant for diseases caused by these two bacteria. In the research, the concentrations used for each test bacteria were 50%; 25%; 12.5%. in observing S. aureus bacteria 1x24 hours with a concentration of 50%, the size of the inhibitory zone was 16 mm, the 25% concentration was 11 mm and the 12.5% ​​concentration was 9 mm. Meanwhile, E. Coli bacteria did not show any reaction to the heruk peel extract.

This study aims to identify the phenomenon of gadget addiction among Pharmacy students at Muhammadiyah University Makassar through a qualitative literature review. Excessive gadget use has become a global issue, with students often being particularly vulnerable due to academic demands and easy access to technology. The research methodology employed is qualitative literature review, encompassing various sources such as scientific journals, books, and research reports on gadget addiction and its impact on students. Literature analysis involved identifying key themes emerging from the reviewed sources. Findings indicate that gadget addiction can affect various aspects of students' lives, including reduced study concentration, poor sleep quality, and decreased face-to-face social interaction. Additionally, the study found a correlation between gadget addiction and increased levels of stress and anxiety among students. The study concludes that gadget addiction is a significant phenomenon among Pharmacy students and underscores the importance of university interventions to mitigate its negative effects. Recommendations include education on healthy gadget use and provision of psychological support for students.

This research aims to analyze the breakfast habits of teenagers at SMK Negeri 3 Bogor. The impact of skipping breakfast is that it causes weight gain, increasing the risk of disease. The recommended breakfast time is 7 or 8 in the morning because they have enough time for breakfast. According to most students, breakfast is a healthy lifestyle and affects their concentration and enthusiasm for studying at school and so that students have a strong immune system. The data collection technique in this research is by distributing a questionnaire which is distributed via the Google Form application which contains 16 statements that have passed validation tests and reliability tests. Other data collection was carried out by reading literature books, the internet, and articles related to the problem topic. The number of respondents in this study was 188 people, 46 men with a percentage of 24.5% and 142 women with a percentage of 75.5%. The indicators contained in the questionnaire include the benefits of breakfast, the impact of breakfast, the time of breakfast, the variety of breakfast, the type of breakfast consumed, and the amount of breakfast. Based on the results of this research, it can be concluded that many factors influence the breakfast habits of teenagers at SMK Negeri 3 Bogor.

Coated tablets are compressed tablets that are coated with a mixture of various substances such as: resin, gum, fillers, sugar, plasticizers, polyols, coloring agents, and flavor enhancers in the active substance. The types of coated tablets that are developing are sugar-coated, thin-coated and enteric-coated tablets. One of the additional materials that plays an important role in making coated tablets is a binder. This review article aims to obtain information and examine what is a good concentration of binder to use in coated tablet formulations. Based on a literature study from several articles collected, it can be concluded that the lactose binder, porang tuber starch, and PVP in several coated tablet dosage formulations, these binders have no effect on the physical properties of the dosage form.

. Avocado seeds are one of the plants used as a medicine for diabetes mellitus with the Latin name (Persea americana Mill.). Avocado seeds contain compounds such as alkaloids, flavonoids, saponins, tannins and triterpenoids which are beneficial for health. This study aims to determine the effect of avocado seed extract (Persea americana Mill.) on the growth of Staphylococcus aureus bacteria in diabetic wounds using the disc diffusion method. The extraction process is by maceration using 96% ethanol. The treatment was repeated 4 times with extract concentrations of 25%, 50%, 75%, 100%, as a positive control Ciprofloxacin and DMSO (Dimetyl Sulfoxide) as a negative control. The results of phytochemical screening show that avocado seeds contain alkaloids, flavonoids, saponins, tannins and triterpenoids. Based on the results of research conducted, avocado seed extract can inhibit the growth of Staphylococcus aureus bacteria as an inhibition zone is formed. The most effective concentration in inhibiting the growth of Staphylococcus aureus bacteria is at 100% concentration of 10.14 mm.

The process of identifying the ripeness level of cayenne peppers is an important step in cultivation and post-harvest handling. Dependence on the quality factors of farmers, such as visual diversity and differences in ripeness perception, results in subjective harvest outcomes. This manual process is also prone to inconsistent results, as humans have time limitations, fatigue, and sometimes lack concentration when sorting for long periods. To minimize these issues, technological intervention is needed to mechanically classify the ripeness level of cayenne peppers. This research aims to develop a classification model for the maturity level of cayenne pepper plants. This research proposes the use of the CNN method for feature extraction and KNN for data classification based on the features extracted by CNN. From the test scenarios carried out, the classification carried out by KNN based on CNN feature extraction got the best accuracy of 99.33%, while the CNN classification model got the best accuracy of 87.33%.

Dysmenorrhea is a gynecological complaint resulting from an imbalance of the hormone progesterone in the blood, resulting in pain. The impact of menstrual pain is very diverse, including young women being unable to walk, having difficulty sleeping, being in a bad mood, losing concentration in doing something, and so on. Gymnastics is a relaxation technique for experiencing dysmenorrhea. To find out nursing care for adolescents with reproductive disorders, dysmenorrhea, the design used in this scientific report is a case study. This case study results from the application of Evidence Based Practice (EBP), client K experienced moderate dysmenorrhea pain on a scale of 4 after being given the intervention, decreasing to mild pain on a scale of 2, client R experienced mild dysmenorrhea pain with a pain scale of 3 after being given the intervention, decreasing to mild pain on a scale of 1 and client S experienced mild dysmenorrhea pain with a pain level of 3 after being given the intervention, decreasing to no pain on a scale of 0. Applying Evidence Based Practice (EBP) it can be concluded that dysmenorrhea exercises can reduce the dysmenorrhea pain experienced by young women during menstruation.

Introduction : Indonesia is country that passed by the equator causing sunlight intensity increase that causes skin problems. Sunscreen is a cosmetic which used to protect skin from sun exposure. Kawista stem bark (Limonia acidissima Groff) has a flavonoid dan phenolic as UV protector. This study analyzed SPF values of ethanol extract, n-hexane fraction, etil acetate fraction, water fraction and sunscreen cream. Method : Spesific and non spesific standardization of ethanolic extract. Extraction using maceration method with 96% ethanol. The suncreen cream were made in 2% (F1), 4% (F2) and 6% (F3) concentration. Physical characteristics has tested include organoleptic, homogeneity, pH, dispersibility and adhesion and viscosity. Oneway ANOVA and kruskall wallis test statistic analysis. Oneway ANOVA and kruskall wallis test statistic analysis. Result : SPF values on F1 is 3,63 (minimal protection); F2 is 7,53 (Extra protection) and F3 is 15, 43 (Ultra protection). Conclusion : All three cream formula has a different significant SPF values (p < 0,05). The suncreen cream fulfilled the requirements of physical characteristics.

Diabetes Mellitus (DM) or what is commonly called diabetes is a chronic metabolic disorder caused by the insulin hormone in the body which cannot be used effectively to regulate blood sugar balance, thereby increasing the concentration of sugar levels in the blood. The aim of this community service is to increase community knowledge regarding diabetes mellitus. The benefits of community service activities are providing education about diabetes. The location of the community service activities is at BTN Bukit Permai in the Kerka Community Health Center Unit 1 Sumbawa area. This community service activity has been carried out well involving public health students and nursing students, in carrying out outreach activities to the community with the title "Productive Healthy Living Free of Diabetes with Health Education about Diabetes Mellitus in the Pkm Unit 1 Sumbawa Working Area" on Saturday 29 June 2024