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Patient satisfaction with healthcare services remains a major concern in the delivery of healthcare. The behavior of healthcare workers, including friendliness, politeness, and communication skills, plays an important role in improving patient satisfaction. Preliminary data indicated that the number of BPJS patient visits at BLUD UPTD Puskesmas Mokoau had decreased annually, while the results of the patient satisfaction survey were still not optimal because several health programs had not achieved the targeted service standards. This study aimed to analyze the relationship between the quality of healthcare services and BPJS patient satisfaction in the working area of Puskesmas Mokoau in 2025. This research applied a quantitative method with a descriptive-analytic approach using a cross-sectional study design. The study involved 306 respondents selected through a random sampling technique, ensuring that each member of the population had an equal opportunity to be chosen as a research sample. Data were collected using questionnaires and analyzed through the Chi-Square test. The findings revealed significant relationships between facilities, procedures, interaction, and communication with BPJS patient satisfaction, with each variable obtaining a P-value of 0.000 (<0.05). Therefore, the quality of healthcare services is closely associated with the level of patient satisfaction, indicating that healthcare workers need to improve service quality effectively and professionally.

High consumption of sugar-sweetened beverages (SSBs) has become an increasing public health concern, particularly among adolescents. Excessive SSB intake is a major risk factor for various non-communicable diseases, including type 2 diabetes mellitus, cardiovascular diseases, obesity, dental caries, and certain types of cancer. This study aimed to analyze the factors associated with the level of sugar-sweetened beverage (SSB) consumption among adolescents. This study employed a descriptive literature review approach. Data were obtained from national and international journals relevant to the topic of SSB consumption among adolescents. The selected articles were analyzed to identify factors associated with SSB consumption. The findings indicated that SSB consumption among adolescents is influenced by several factors, including individual factors (gender and knowledge), socioeconomic factors (peer influence and pocket money allowance), environmental factors (mass media exposure and beverage availability), and psychological factors (stress level and preference for sweet tastes). This study highlights that SSB consumption is a multifactorial behavior influenced by various interacting determinants. Therefore, comprehensive interventions targeting both individual and environmental factors are needed to reduce SSB consumption among adolescents.

Work stress is a critical occupational health concern among midwives working at primary healthcare facilities. This cross-sectional study aimed to analyze factors associated with work stress among 30 midwives, including age, marital status, length of service, and dual-role conflict. Data were collected using structured questionnaires measuring work stress (9 valid items) and dual-role conflict (6 items), and analyzed through univariate, bivariate (Fisher's Exact Test and Chi-Square), and multivariate (binary logistic regression) analyses. Results showed that 43.3% of midwives experienced high work stress and 53.3% reported high dual-role conflict. Bivariate analysis revealed significant associations between work stress and marital status (p=0.009) and dual-role conflict (p=0.004), while age (p=0.633) and length of service (p=0.586) were not significant. Multivariate analysis identified dual-role conflict as the primary determinant of work stress (OR=15.762; 95% CI: 2.149–115.631; p=0.007). Healthcare facility management should develop gender-responsive policies and workplace stress intervention programs to reduce dual-role conflict and work stress among midwives.

Dental caries is an oral health problem associated with the activity of Streptococcus mutans. Water hyacinth (Eichhornia crassipes) contains bioactive compounds such as flavonoids, tannins, and alkaloids with antibacterial potential. This study aimed to evaluate the effectiveness of water hyacinth extract against the growth of Streptococcus mutans. The research method used was an in vitro experimental study with a post test only group design. A total of 24 samples were divided into four treatment groups with extract concentrations of 6.25%, 12.5%, 25%, and 50%. Antibacterial activity was tested using the disc diffusion method on Mueller Hinton Agar media. Data were analyzed using the Kruskal-Wallis and Mann-Whitney tests. The results showed that water hyacinth extract inhibited the growth of Streptococcus mutans. The largest inhibition zone was observed at 50% concentration, while the smallest was found at 6.25% concentration. Kruskal-Wallis analysis showed significant differences among groups (p<0.05). In conclusion, water hyacinth (Eichhornia crassipes) extract has antibacterial activity against Streptococcus mutans.

Preeclampsia is a pregnancy complication that significantly contributes to maternal and neonatal morbidity and mortality worldwide. Globally, it affects approximately 3–8% of pregnancies and causes more than 70,000 maternal deaths each year. In Indonesia, preeclampsia accounts for around 30% of the 4,151 maternal deaths reported in 2024. In Padang City, there were 254 cases in 2023 and 129 cases in 2024, with Puskesmas Bungus having the highest prevalence (7.2% and 3.77%). This study aimed to analyze the association between body mass index (BMI), history of hypertension, and history of preeclampsia with the incidence of preeclampsia among pregnant women at Puskesmas Bungus, Padang. This study used a quantitative case-control design involving 50 cases and 50 controls. Data were analyzed using chi-square and logistic regression tests. The results showed significant associations between obesity (p=0.031; OR=2.897), history of preeclampsia (p=0.006; OR=13.821), and history of hypertension (p=0.002; OR=17.216) with the incidence of preeclampsia. Multivariate analysis identified history of hypertension as the most dominant factor associated with preeclampsia. This study concludes that obesity, history of hypertension, and history of preeclampsia are significant risk factors for preeclampsia among pregnant women. Strengthening early detection and routine antenatal care for high-risk pregnancies is necessary to reduce maternal complications associated with preeclampsia.

Circulating tumor DNA (ctDNA) has emerged as a promising liquid biopsy biomarker for real-time monitoring of tumor dynamics. In urothelial carcinoma (UC), effective monitoring of treatment response remains a clinical challenge due to the limitations of conventional imaging and invasive procedures. This systematic review aims to synthesize the existing evidence on the association between ctDNA dynamics and treatment response monitoring across various stages and therapeutic settings. A comprehensive systematic review was conducted. We included cohort studies, randomized controlled trials, and meta-analyses that evaluated ctDNA in UC patients undergoing treatment. Data were extracted on patient population, methodology, treatment, sampling strategy, clinical outcomes, and statistical associations. The review encompassed 80 studies. Baseline ctDNA positivity was strongly prognostic, associated with a 4- to 6-fold increased risk of recurrence or death (HR 4.23-6.56). Dynamic ctDNA clearances or significants reduction during treatment, were strongly associated with improved outcomes. Showing hazard ratios for adverse events as low as 0.10-0.31. ctDNA demonstrated time advantages of 53-90 days over radiographic detection. ctDNA is a potent tool for monitoring treatment response in urothelial carcinoma. It provides superior prognostic and offers a significant lead time for detecting treatment failure. Future research must focus on standardizing methodologies and validating ctDNA-guided therapeutic.

Muscle-invasive bladder cancer (MIBC) is an aggressive malignancy associated with high morbidity, reduced survival, and impaired quality of life. Radiotherapy (RT) has been widely used as a bladder-preserving strategy, particularly for patients unsuitable for surgery or systemic chemotherapy. RT may also enhance tumor immunogenicity through programmed death-ligand 1 (PD-L1) upregulation, providing a rationale for combination therapy with immunotherapy. This study aimed to evaluate the effectiveness of combining immunotherapy and radiotherapy in MIBC treatment. A systematic review was conducted following PRISMA 2020 guidelines using the PICO framework. Literature searches were performed in PubMed, Embase, Cochrane, ClinicalTrials.gov, Web of Science, and Scopus databases for studies published between 2016 and 2025. Risk of bias was assessed using the Cochrane Risk of Bias Tool and ROBINS-I. Of 105 identified studies, five met the inclusion criteria and were included in the final analysis. Only one Phase II randomized controlled trial demonstrated low risk of bias in randomization and allocation concealment. ROBINS-I assessment indicated moderate to serious risk in confounding and participant selection domains. Clinical findings showed promising outcomes, with complete response rates ranging from 35%–50% and partial response rates from 25%–40%. Median overall survival ranged from 24–30 months, with favorable disease-free and progression-free survival outcomes. Combined immunotherapy and radiotherapy demonstrate potential to improve survival and disease control in MIBC; however, further rigorous clinical studies are needed to optimize patient-centered treatment strategies.  

Risk factors for melasma have been identified at several points such as the use of birth control pills, cosmetics, sun exposure, estrogen therapy, decreased thyroid and ovarian function, ovarian tumors, nutrition, drugs that are classified as phototoxic or photoallergic, and epilepsy drugs. This article aims to determine the incidence of melasma and its risk factors. This study uses articles collected from the Google Scholar database. The data collection step uses the keyword "Risk Factor Melasma" according to the title and keyword criteria. The articles used are publications in the 2018-2023 year range. The stages of analysis are carried out using VOSviewer software for visualization and trend analysis in the form of bibliometric maps. The bibliometric approach was applied to identify publication patterns, research developments, and relationships among topics related to melasma risk factors. Based on the visualization results, 100 selected documents were published within 5 years, from 2018 to 2023. The findings provide an overview of the main research trends and contribute to a better understanding of the incidence of melasma and the factors associated with its occurrence

This research examines the potential application of the Right to Be Forgotten (RTBF) in Indonesia's criminal justice system, focusing on individuals who have been acquitted or have completed their sentences. The study explores the legal, social, and ethical implications of RTBF in relation to criminal records, aiming to assess how it could support the rehabilitation and reintegration of acquitted individuals. In Indonesia, criminal records often remain publicly accessible long after a person has been legally exonerated, creating barriers to social reintegration due to the stigma associated with past accusations. The study investigates the gaps in the current legal framework, such as the lack of provisions for the removal or anonymization of criminal records for acquitted individuals, and explores how RTBF could promote justice and fairness. The research uses a literature review methodology, analyzing relevant legal texts including Law No. 11 of 2008 on Information and Electronic Transactions (ITE Law), Law No. 39 of 1999 on Human Rights, and the 1945 Indonesian Constitution. The review critically evaluates the challenges and opportunities of implementing RTBF, focusing on balancing privacy rights with public safety concerns. The findings suggest that RTBF could reduce the negative impact of criminal records on individuals who have been acquitted, facilitating their reintegration into society. However, the study also highlights the challenges in implementing RTBF due to societal and legal factors. Legal reforms recommendations allow individuals to request the removal of criminal records, aligning Indonesia's legal system with international human rights standards.

Environmental-based diseases remain a major public health issue associated with unsafe drinking water, inadequate sanitation, poor hygiene behavior, improper household waste management, and unsafe domestic wastewater disposal. Community-Based Total Sanitation, known in Indonesia as Sanitasi Total Berbasis Masyarakat or STBM, is a community empowerment approach designed to change hygiene and sanitation behavior through five pillars. This article aims to develop an STBM program planning design and an impact evaluation model for reducing environmental-based diseases, particularly diarrhoeal disease. This study used a narrative review method by analyzing national regulations, official guidelines, global WASH reports, and recent scientific literature. The proposed program design includes situation analysis, multisectoral advocacy, community triggering, household mentoring, strengthening sanitation facilities, monitoring, verification, and impact evaluation. The evaluation model uses process, output, outcome, and impact indicators, with diarrhoea incidence as the main measurable health indicator. The findings indicate that an integrated STBM program supported by community participation, valid baseline data, and periodic evaluation can strengthen the prevention of environmental-based diseases. This article recommends implementing STBM as a sustainable community-based public health intervention rather than a short-term sanitation activity. 

The Integrated Primary Care Posyandu (ILP) program requires cadres to assume a much broader role compared to conventional Posyandu services. In the working area of Puskesmas Penusupan, ILP achievement reached only 20% in 2025, while merely 25 out of 225 cadres (11%) had received related training. This condition indicates that cadre readiness needs to be examined more comprehensively before the program can be implemented optimally. This study aimed to analyze the factors associated with the readiness of ILP Posyandu cadres using a descriptive-analytic method with a cross-sectional approach. The study involved 144 cadres selected proportionally from a population of 225 using the Slovin formula. Data were collected through structured interviews using a validated questionnaire and analyzed using univariate, bivariate (Spearman Rank), and multivariate (ordinal logistic regression) analyses. The results showed that among the eight variables examined, only skills (r = 0.171; p = 0.040) and resource availability (r = 0.225; p = 0.007) were significantly associated with cadre readiness. In the multivariate analysis, resource availability emerged as the most influential factor with an OR = 2.839 (95% CI: 1.311–6.149), indicating that cadres supported by adequate resources were 2.8 times more likely to demonstrate good readiness. In conclusion, resource availability was identified as the dominant factor associated with the readiness of ILP Posyandu cadres in the working area of Puskesmas Penusupan. Therefore, improving the availability of facilities and infrastructure, providing practice-based training, and strengthening operational support should become priority programs in the future.

Diabetes Mellitus is a non-communicable disease with an increasing prevalence and has become a major public health concern globally and nationally. The incidence of diabetes mellitus is influenced by various individual and environmental factors. This study aimed to analyze the relationship between age, gender, and residential proximity to landfill areas and the incidence of diabetes mellitus in Bendosari District. A quantitative analytic observational design with a cross-sectional approach was employed. The study population consisted of 1,890 patient visit records recorded in the Management Information System of Bendosari Public Health Center in 2025. A total of 363 respondents were selected using proportionate stratified random sampling. Data were analyzed through univariate analysis, bivariate analysis using the Chi-Square test, and multivariate analysis using multiple logistic regression. The findings showed that age was significantly associated with diabetes mellitus incidence (p=0.000; OR=79.790; 95% CI=53.511–118.974). Gender was also significantly related to diabetes mellitus incidence (p=0.000; OR=0.298; 95% CI=0.203–0.435), indicating that females had a higher risk than males. In contrast, residential proximity to landfill areas was not significantly associated with diabetes mellitus incidence (p=0.308; OR=1.247; 95% CI=0.439–3.540). Multivariate analysis revealed that age and gender were the dominant factors influencing diabetes mellitus incidence, with the model explaining 56.1% of the variation. The study concludes that age and gender are significant determinants of diabetes mellitus incidence, whereas residential proximity to landfill areas has not been proven to significantly affect its occurrence.

Allergic rhinitis (AR) is a chronic inflammatory disorder of the nasal mucosa mediated by immunoglobulin E (IgE) in response to allergen exposure. This condition has become a significant global health concern because of its increasing prevalence and substantial impact on quality of life, sleep, cognitive function, and work productivity. AR is also commonly associated with other atopic diseases, including asthma and atopic dermatitis. This article aims to review the current understanding of allergic rhinitis, focusing on epidemiology, pathophysiology, clinical manifestations, diagnostic approaches, and evidence-based management strategies. This study used a narrative literature review method by analyzing scientific articles, clinical guidelines, and peer-reviewed journals published between 2015 and 2025. Literature sources were obtained from PubMed, Google Scholar, and relevant medical databases using keywords related to allergic rhinitis, IgE, diagnosis, and immunotherapy. The findings indicate that allergic rhinitis involves complex immune mechanisms characterized by Th2 lymphocyte activation, IgE production, and inflammatory mediator release. Diagnosis is primarily established clinically and supported by allergy testing such as skin prick tests or serum-specific IgE measurement. Intranasal corticosteroids remain the first-line therapy for moderate to severe cases, while antihistamines and leukotriene receptor antagonists are used as adjunctive therapies. Allergen immunotherapy has shown effectiveness in modifying disease progression and improving long-term outcomes. In conclusion, allergic rhinitis is a manageable chronic disease that requires a comprehensive and individualized treatment approach involving environmental control, pharmacotherapy, and immunotherapy.

Geographic tongue or benign migratory glossitis is a benign disorder of the oral mucosa that is relatively common in dental practice. This condition is characterized by erythematous areas caused by the loss of filiform papillae surrounded by irregular white borders. To understand the clinical characteristics of geographic tongue and the contributing factors involved in the development of the lesion in order to establish an appropriate diagnosis and provide adequate patient education. A 25-year-old female patient presented with complaints of patches on the tongue for approximately two months. The patient had been following an OMAD (One Meal A Day) diet for one year and reported an allergy to white rice. The patient also had a history of psoriasis. Nutritional deficiencies such as vitamin B complex, vitamin B12, folic acid, iron, and zinc may affect the integrity of the oral mucosa and disrupt the regeneration of the lingual epithelium. These conditions may lead to atrophy of the filiform papillae, resulting in the characteristic erythematous appearance of geographic tongue. In addition, immunological and inflammatory factors associated with psoriasis are also suspected to contribute to lesion development. Geographic tongue is a benign inflammatory condition with a multifactorial etiology, including nutritional deficiencies and immunological factors such as psoriasis. Evaluation of systemic conditions and nutritional status is important to support accurate diagnosis and proper patient management.

The development of digital media has transformed virtual public spaces into major arenas for shaping public opinion on religious issues, including Islamic law and sharia in Indonesia. Discussions surrounding sharia on social media are frequently accompanied by stigma and misperceptions influenced by media framing, digital algorithms, and identity polarization. This study aims to analyze the construction of stigma toward Islamic law in the digital era, identify forms of sharia misperception in the Indonesian public sphere, and explain factors contributing to the reproduction of such stigma. This research employs a qualitative approach based on an integrative literature review combined with digital media discourse analysis. Data were collected through scientific literature reviews, social media observations, and analysis of digital content related to sharia discourse. The findings reveal that sharia is often associated with violence, anti-democracy, restrictions on women’s rights, and opposition to modernity due to media simplification and emotionally driven digital content. In addition, low levels of religious digital literacy and the prevalence of echo chambers reinforce the spread of stigma toward Islamic law in virtual public spaces. This study emphasizes the importance of strengthening religious digital literacy and promoting moderate and inclusive Islamic narratives in contemporary digital society.

The term "breach of contract" in contract law refers to a breach of promise. Discussions of breach of contract, both in doctrine and jurisprudence, are usually associated with a statement of negligence by the debtor, where the debtor has failed to properly fulfill their contractual obligations, and the debtor is at fault. It must be acknowledged that a breach of contract, or breach of promise, already involves bad faith on the part of the party failing to fulfill their promise. The meaning of "breach of contract" in banking law relates to the occurrence of problem loans at banks, which cause the loan to become non-performing. This is usually due to the debtor or customer not paying by the previously agreed payment date. The existence of a breach of contract is inseparable from the existence of a credit agreement. Whether a debtor is in default cannot be determined simply because there are efforts to rescue loans that have entered a problematic stage. The beginning of a violation of an agreement or default due to someone not being paid, in meeting the credit rescue standards at the bank, usually efforts are made such as Rescheduling, Reconditioning, Restructuring, through this rescue, the debtor is given the opportunity to lose his business, so the concept of default in BW and the Banking Law must be measured through the performance given, in both regulations, then from there the concept of problem credit can be classified. This banking regulation can be said to be a default, the comparison of this concept is the discussion in this thesis.

The quality of rice that is suitable for consumption, one of which is determined by the absence of associated components when the rice is in storage. Rice storage is carried out by means of long shelf life and good rice quality. Damage to rice due to pest attacks causes a decrease in quality and quantity. Environmentally friendly efforts are needed to control the rice weevil Sitophilus oryzae using vegetable materials. This study sought to ascertain the death rate of rice weevils treated with lemongrass stem (Cymbopogon citratus), bay leaves (Syzygium polyanthum), and pandan leaves (Pandanus amaryllifolius). The study employed a fully randomized design with three treatments in the form of simplicia plant components. There were 21 study units because each treatment included seven repetitions. Each treatment used 20 rice weevil imago breeding results which were infested in a jar containing 200 g of rice for 4 weeks in the laboratory. The use of pandan leaf, bay leaf, and lemongrass simplicia at 7 days after treatment showed the proportion of rice weevil mortality was 59,29%, 39,29%, and 50,00%, respectively. As for the observations of 14 day after treatments, 21 day after treatments, and 28 day after treatments showed that the mortality rate of all rice beetles was above 50%. Regarding the percentage of rice powder, hollow rice, and rice weight loss, the findings of observations on rice weevil mortality did not reveal any significant variations across all treatments.

Iron deficiency anemia (IDA) is a condition of insufficient iron that lowers hemoglobin levels and disrupts erythrocyte formation. This condition commonly occurs in children and can weaken the immune system, thereby increasing the risk of recurrent respiratory tract infections such as bronchiolitis, pneumonia, and Acute Respiratory Tract Infections (ARTI). Children with IDA are also at risk of worsening clinical conditions. This study employed a literature review method with a descriptive-analytical approach. A total of 10 journals (2020–2026) from Google Scholar, PubMed, ResearchGate, Elsevier, and the National Center for Biotechnology Information (NCBI) were analyzed using the Population, Intervention, Comparison, Outcome, Study Design (PICOS) framework and synthesized narratively. The results of the review indicate that iron deficiency anemia is significantly associated with an increased risk of recurrent respiratory tract infections in children. Children with IDA have a 2–5 times higher risk of developing bronchiolitis and pneumonia, and up to 10 times greater susceptibility to recurrent ARTI. This condition is also associated with increased disease severity, characterized by low hemoglobin levels, mean corpuscular volume (MCV), and serum iron, as well as elevated total iron-binding capacity (TIBC). Iron supplementation has been proven effective in reducing the incidence of recurrent infections. In conclusion, iron deficiency anemia is associated with an increased risk and severity of recurrent respiratory tract infections in children. Early detection and iron supplementation are essential to reduce morbidity and prevent infection recurrence.

In Islam, prayer (salat) is a fundamental obligation that must be performed under all circumstances, including during illness. Muslim patients have high spiritual needs, in which religious practices serve as a source of strength in coping with disease. Although Islam provides concessions (rukhsah) in performing prayer for the sick, limitations in patients’ understanding of how to perform prayer according to their health conditions are still found. This lack of knowledge may affect the proper practice of prayer during hospitalization. Therefore, this study aims to identify patient characteristics related to the practice of prayer, to examine the level of knowledge of the five daily prayers in relation to their practice among patients, and to analyze patients’ overall level of knowledge regarding prayer. This study employed a quantitative method with a cross-sectional design. The results show that patient characteristics, particularly productive age and higher educational level, contribute to their ability to perform prayer during hospitalization. A significant relationship was found between the level of knowledge of prayer and its practice, where better understanding was associated with more optimal religious practice. Overall, most patients had a high level of knowledge of prayer, although a small proportion still had low knowledge, indicating the need for spiritual education. It can be concluded that the level of knowledge of prayer is associated with the quality of prayer practice among Muslim patients at RSUD Haji Makassar. Strengthening spiritual education is needed to support the fulfillment of patients’ religious needs during hospitalization.

Knee septic arthritis is an orthopedic emergency that requires prompt and appropriate management to prevent permanent joint damage and systemic complications. Inflammatory markers such as erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) are commonly used for diagnosis and monitoring of treatment response; however, their prognostic value after surgical debridement remains variable. This systematic review aimed to evaluate the role of ESR, CRP, and platelet count as prognostic indicators following irrigation and/or surgical debridement in patients with knee septic arthritis. A literature search was conducted in January using PubMed, Google Scholar, ScienceDirect, Wiley Online Library, SpringerLink, and Semantic Scholar, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Study quality was assessed using the National Heart, Lung, and Blood Institute (NHLBI) tools. Fifteen studies meeting the inclusion criteria were qualitatively analyzed. The findings indicate that elevated preoperative CRP levels and delayed postoperative CRP reduction are associated with unfavorable clinical outcomes, including failure of infection eradication and the need for repeat debridement. Although ESR is consistently elevated during the acute phase, its slower decline limits its short-term prognostic utility. Platelet count may increase as part of the systemic inflammatory response but shows inconsistent prognostic value.