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Vitamin A Deficiency (VAD) and iron deficiency anemia (IDA) are global nutritional issues affecting children, particularly in developing countries. The interaction between these two conditions can lead to a more complex condition known as Vitamin A Deficiency Anemia (VADA). This study aims to review the molecular relationship between Vitamin A deficiency and iron metabolism leading to VADA, as well as its impact on children's health. The methodology used in this article is a literature review of various clinical studies, epidemiological research, and relevant molecular experiments. The results show that VADA is primarily a functional iron deficiency, where iron absorption is impaired despite overall body iron levels not being critically low. This mechanism involves the regulation of hepcidin, redistribution of iron, and its effects on erythropoiesis. Additionally, therapy with Vitamin A supplementation has been shown to increase erythropoietin and hemoglobin production in children with dual deficiencies. The implications of these findings highlight the need for more integrated therapeutic strategies that consider both Vitamin A and iron status simultaneously. Further research is needed to understand the molecular mechanisms more deeply involved in this interaction and to develop more effective therapies for children with VADA.

The pregnancy period is a crucial time for ensuring the health of the mother and fetus through the provision of balanced nutrition. However, nutritional issues such as anemia and chronic energy deficiency (CED) are still commonly found among pregnant women. The use of local nutritious foods, such as moringa leaves (Moringa oleifera), can be a potential solution to support nutritional needs. This community service activity aims to improve the knowledge and skills of pregnant women in preparing healthy menus and balanced eating patterns using moringa leaves. The activity was carried out through interactive lectures, coaching on menu preparation, cooking demonstrations of moringa leaf dishes, and evaluation through pre-tests and post-tests. The participants were pregnant women in the working area of the Wara Selatan Health Center in Palopo City, totaling 25 people. The results showed an increase in participants' nutritional knowledge, with an average pre-test score of 55 rising to 82 in the post-test. Participants were also able to prepare a balanced daily menu based on moringa leaves and produce several processed products, including moringa soup, moringa fritters, and moringa pudding. It can be concluded that the healthy menu coaching activity using local moringa leaves effectively improves the knowledge and skills of pregnant women regarding balanced nutrition. The use of local foods such as moringa leaves has the potential to support the improvement of maternal nutritional status in a simple, economical, and sustainable manner.

A 64-year-old male patient presented to the emergency department (ED) of RS Cut Meutia with complaints of left-sided chest pain radiating to both arms, which had been occurring for two days prior to his hospital admission. The chest pain was described as sharp, sudden, and progressively worsening, and it persisted without relief from positional changes. The pain intensity was rated as 9/10 and was accompanied by cold sweats and nausea. The patient had a history of type 2 diabetes mellitus for 15 years and had been on antidiabetic medications, although he could not recall the names of the medications. The patient was a smoker but had quit smoking upon being diagnosed with diabetes. Vital signs and general status were within normal limits upon examination. Local examination of the heart revealed a murmur on auscultation. Laboratory results showed anemia, leukocytosis, hyperglycemia, and hypercholesterolemia. Electrocardiography (EKG) indicated signs of inferior STEMI (ST-Elevation Myocardial Infarction). The patient was treated with furosemide 1 amp/12 hours, atorvastatin 1x20 mg, arixtra 1x0.25 mg, aspilet 1x8 mg, clopidogrel 1x75 mg, nitrokaf retard 2x2.5 mg, and bisoprolol 1x2 mg, along with non-pharmacological management, including three-way catheter insertion and oxygen therapy at 2-4 liters per minute. Acute Coronary Syndrome (ACS) carries a poor prognosis if not managed promptly and correctly. Understanding the appropriate management of ACS is crucial in preventing further myocardial occlusion and improving patient outcomes. Therefore, rapid and accurate intervention is vital in improving the prognosis for patients with ACS.

Low Birth Weight (LBW) is a condition in which a newborn weighs less than 2.5 kg, generally caused by premature birth (<37 weeks) or intrauterine growth restriction. LBW increases the risk of health problems such as growth delays, cognitive impairments, infections, respiratory disorders, cardiovascular issues, gastrointestinal problems, kidney disorders, and higher rates of infant morbidity and mortality. This study aimed to identify factors associated with LBW in the working area of Rosalina Munthe Clinic. The study used an analytical design with a cross-sectional approach, and data were analyzed using univariate and bivariate methods with SPSS. Results showed that 33.3% of respondents had LBW infants. Mothers with unsafe age were 39.7%, those with unsafe pregnancy intervals were 61.9%, low socioeconomic status was found in 66.7%, and low educational level in 81%. Analysis revealed a significant association between maternal age and LBW incidence. However, pregnancy interval, anemia, and socioeconomic status showed no significant association with LBW. This study highlights that maternal age plays a key role in LBW occurrence, while other factors require further investigation to understand their contribution to the risk of delivering low birth weight infants.

The number of school-age adolescent girls in Banggai Regency, Central Sulawesi, still faces serious challenges related to nutritional problems such as anemia and chronic energy deficiency (SEZ). Low nutritional literacy and unbalanced food consumption habits also worsen their nutritional status, especially during puberty when nutritional needs increase significantly. This service activity aims to increase the understanding and awareness of young women on the principles of balanced nutrition through a participatory educational approach. The implementation of the activity was carried out at SMP Negeri 2 Bunta, Simpang Raya District, involving 30 students in grades VII and VIII as well as UKS supervisory teachers. The intervention included providing material on "Fill My Plate", the 4 pillars of balanced nutrition, and the risk of nutritional disorders in adolescents. The material was delivered in the form of interactive counseling using leaflet media, accompanied by knowledge measurement through pre-test, post-test, and one-week post-activity evaluation. The results of the activity showed a significant increase in students' understanding of the principles of balanced nutrition, with the knowledge score of the good category increasing from 40% to 87%. Most of the participants were able to mention the composition of the meal portion, the importance of breakfast, restrictions on fast food consumption, and the need to drink enough water every day. This activity also has an impact on increasing the capacity of teachers in assisting and monitoring the health status of students through the UKS program. Teachers become more active in conducting periodic counseling and recording the nutritional development of female students on a regular basis. School-based balanced nutrition counseling has been proven to be effective in improving adolescent nutritional literacy. This educational model can be replicated in other regions with cross-sectoral support such as education offices, health centers, and village governments, to support the achievement of sustainable development goals in the health sector.

The development targets in the Health sector in the 2020–2024 National Medium-Term Development Plan (RPJMN) place one of the main targets for maternal and child health is to reduce the incidence of children under five years old (toddlers) stunting (low height / short) by 30.8% (2018) to 19% in 2024. Optimal Health Status must be prepared since a woman before marriage. Then continued when the woman is pregnant, and while breastfeeding. Childhood is the foundation for growth and development in the next stage, if there are nutritional problems then the consequences that arise are permanent. The risk of stunting by 7x can occur in women 15-49 years who experience anemia and when they become pregnant will be at risk of giving birth to stunted babies. In women of childbearing age aged 15-49 years is the foundation for growth and development in the next stage, if during this period women experience nutritional problems then the consequences that arise can be permanent or irreversible. Its essence is a critical period when a system is plastic and sensitive to its environment, followed by a permanent loss of plasticity and functional capacity (Ummi Kalsum et al., 2021). Before education was provided, most adolescents showed a low level of understanding, namely 31 respondents (56.7%), and awareness of the importance of monitoring nutritional status during adolescence was also minimal. However, after interactive counseling with an easy-to-understand approach, there was a significant increase in knowledge, with 41 respondents (68.3%) showing an increase in understanding, reflected in a change in the knowledge category to a better level. This activity emphasizes the importance of promotive and preventive interventions in areas at high risk of nutritional problems. The implementation of direct and participatory education involving cadres and health workers has proven effective in increasing awareness and forming healthy lifestyle behaviors in adolescents. Therefore, similar education programs need to be implemented continuously to reduce anemia rates to prevent stunting and prevent stunting from adolescence.

Hemoglobin and hematocrit examinations serve as important early indicators of hematological status, reflecting the blood’s capacity to transport oxygen. A decrease in these two parameters leads to anemia, which is often undetected due to minimal early symptoms and low awareness to undergo examinations. This activity was carried out using the Plan-Do-Check-Act (PDCA) approach, by examining hemoglobin and hematocrit levels in adult participants. Capillary blood samples were analyzed using a portable device at the examination location. Education was delivered through leaflets regarding the importance of iron, vitamin B12, and folate intake to support erythrocyte formation. The examination was attended by 104 participants, the majority of whom were women. The average hemoglobin was recorded as approaching the lower limit of normal values, while hematocrit levels showed wide variations. More than half of the participants were classified as having anemia. This high proportion of anemia highlights the urgent need for targeted nutritional education. Hemoglobin and hematocrit screening proves effective as an early detection tool for hematological disorders. Education that is linked to laboratory findings should be prioritized to promote improved dietary patterns, particularly the consumption of iron-rich foods, vitamin B12, and folate, in order to prevent erythropoietic dysfunction and long-term health complications.

Anemia in pregnant women is one of the contributing factors to stunting in toddlers. The consumption of iron (Fe) tablets by pregnant women requires supervision from family members to support the success of the stunting reduction program in Bangli Regency. Iron tablet intervention in pregnant women has been proven to reduce the risk of complications, lower the incidence of low birth weight in infants, and decrease maternal mortality during childbirth. This study used a cross-sectional survey design, involving 48 pregnant women. Data collection was conducted using total sampling during the period from January 2024 to January 2025 at Kintamani IV Public Health Center. Bivariate data analysis was carried out using the chi-square test. The results of the study showed that 68% of pregnant women experienced mild anemia. Most pregnancies were in the third trimester (39%), and 43% of the participants were in their first pregnancy. The majority of the pregnant women had good knowledge levels. There was a significant relationship between pregnant women’s knowledge and their adherence to consuming iron tablets, with a p-value of 0.019. The odds ratio (OR = 5.014) indicated that pregnant women with good knowledge were five times more likely to adhere to iron tablet consumption compared to those with limited knowledge. Support and monitoring of the nutritional status of pregnant women are essential to reduce the incidence of low birth weight and stunting among toddlers in Selulung Village, Kintamani District.  

Background: Maternal nutritional status plays a crucial role in determining both maternal and neonatal health outcomes. According to data from the Indonesian Ministry of Health (2021), the prevalence of anemia among pregnant women reached 48.9%, while in Gorontalo Province, around 30% experienced malnutrition. Poor nutritional status during pregnancy is associated with increased risks of complications, including preterm birth, low birth weight, and higher maternal and neonatal mortality rates. Therefore, nutrition education is considered an essential strategy to enhance knowledge and promote adequate dietary intake among pregnant women.Objective: This study aimed to evaluate the effectiveness of nutrition education in improving the knowledge and nutritional status of pregnant women at the South Bulango Community Health Center. Methods: A quantitative study with a pre-experimental design was conducted involving 30 pregnant women selected through purposive sampling. Inclusion criteria included women aged 18–35 years, free from severe comorbidities, and willing to participate. Data were collected using questionnaires to assess nutritional knowledge, interviews to explore dietary patterns, and anthropometric measurements such as weight, height, and mid-upper arm circumference (MUAC). Data analysis employed descriptive statistics and the Wilcoxon test to assess differences before and after the intervention. Results: Most participants were aged 20–35 years (66.6%), had secondary education (63.3%), and were housewives (60%). Post-intervention results showed a substantial increase in good nutritional knowledge from 13.3% to 60%. Nutritional status also improved progressively across trimesters, with normal MUAC increasing from 33.3% to 60%, while undernutrition declined from 50% to 13.3%. The Wilcoxon test indicated a significant difference (p = 0.000; p < 0.05). Conclusion: Nutrition education effectively enhances both knowledge and nutritional status among pregnant women and should be integrated into routine antenatal care services.

Anemia is a hematological disorder that is often not recognized in the adult age group. One lifestyle factor that can affect hemoglobin and hematocrit levels is the consumption of tea or coffee with meals, because the tannin and polyphenol content inhibits the absorption of non-heme iron. Early detection of hemoglobin and hematocrit levels accompanied by education about eating and drinking habits is an important strategy in preventing anemia. This screening activity is carried out using the Plan-Do-Check-Act (PDCA) approach. Examination of hemoglobin and hematocrit levels is carried out using Point-of-Care Testing (POCT) from capillary blood. Education is provided to all participants through leaflets and group counseling regarding the effect of tea and coffee consumption on iron absorption. A total of 91 participants took part in this activity, consisting of 39.6% men and 60.4% women, with an average age of 47.4 years. The average hemoglobin was recorded at 11.2 ± 1.6 g/dL and hematocrit at 33.0 ± 4.7%. As many as 42.9% of participants experienced anemia based on hemoglobin levels below normal values ​​according to gender. Hemoglobin and hematocrit examinations successfully identified a significant proportion of individuals at risk of anemia. Education on the right time to consume tea or coffee and increasing consumption of foods rich in iron and vitamin C are preventive interventions that can be applied to maintain optimal hematological status.   Keywords: Hemoglobin, Hematocrit, Anemia, Iron, Tea, Coffee, Diet

Background: Iron-containing blood-boosting tablet supplements are crucial for meeting micronutrient needs in pregnant women and children. Micronutrient deficiencies, such as iron, have the potential to cause stunting. This supplementation program is expected to improve the nutritional status of the Indonesian population, prevent stunting, and support optimal growth.Objective: This systematic literature review aims to analyze the relationship between iron-boosting tablet supplements in meeting micronutrient needs and preventing stunting in children (toddlers and infants) in Indonesia.Method: A systematic literature search was conducted to identify relevant articles in 3 main databases (Scopus, PubMed, and Google Scholars). Studies on the consumption of iron-boosting tablets for meeting micronutrient needs in stunting cases require a systematic review with inclusion criteria limited to articles published between 2015-2024, free full text, in Indonesian and English.Results: Of the 10 articles analyzed, most showed that consumption of Iron-Boosting Tablets (TTD) in pregnant women can increase hemoglobin levels and reduce the risk of anemia, which contributes to the prevention of stunting in children. However, the compliance rate of pregnant women in consuming TTD is still low due to side effects and lack of awareness. Additionally, socio-economic factors also play a role in children's nutritional status, where families with low incomes have a higher risk of anemia and stunting.Conclusion: TTD supplementation plays an important role in the prevention of anemia and stunting in children. However, its effectiveness is greatly influenced by the level of consumption compliance and socio-economic factors. Therefore, more intensive education and multi-sectoral policies are needed to improve accessibility and compliance with TTD consumption in stunting prevention efforts in Indonesia.    

Pregnancy anemia is a medical condition that occurs when a pregnant woman experiences a lack of red blood cells or hemoglobin in her blood during pregnancy. Hemoglobin is a protein in red blood cells that is responsible for transporting oxygen from the lungs to the rest of the body and returning carbon dioxide to the lungs to be released. This study aims to determine the relationship between knowledge, age, education and nutritional status with the incidence of anemia in pregnant women in Soppeng district in 2024. The study design used Cross Sectional. Pregnant women at La Temmamala Hospital were 50 people. Based on the results of the Chi-square statistical test, the p Value = 0.273> α = 0.05 was obtained, so H0 was accepted and Ha was rejected, thus it can be concluded that there is no relationship between knowledge and the incidence of anemia in pregnant women at La Temmamala Hospital, Soppeng Regency. Based on the results of the Fisher's Exact Test statistical test, the p Value = 1,000 > α = 0.05 was obtained, so H0 was accepted and Ha was rejected, thus it can be concluded that there is no relationship between age and the incidence of anemia in pregnant women at La Temmamala Hospital, Soppeng Regency. Based on the results of the Fisher's Exact Test statistical test, the p Value = 1,000 > α = 0.05 was obtained, so H0 was accepted and Ha was rejected, thus it can be concluded that there is no relationship between age and the incidence of anemia in pregnant women at La Temmamala Hospital, Soppeng Regency.m Based on the results of the Chi-square statistical test, the p Value = 0.000 <α = 0.05 was obtained, so H0 was rejected and Ha was accepted. Thus, it can be concluded that there is a relationship between nutritional status and the incidence of anemia in pregnant women at La Temmamala Hospital, Soppeng Regency. For the author as information on the importance of mother's knowledge about For the author as information on the importance of mother's knowledge about the importance of ANC examination. For the government in general to optimize the dissemination of information about the importance of conducting pregnancy examinations

Anemia in pregnancy is still a major problem experienced by almost half of pregnant women in all countries in the world including Indonesia. Many pregnant women refuse and do not comply with taking FE tablets for various reasons so that the prevalence of anemia in pregnant women is still high. A mother is said to be compliant with taking FE tablets if ≥ 90 % of the amount should have been taken. Anemia in pregnancy is a national problem because it reflects the value of the socio-economic welfare of the community, and has a very large impact on the quality of human resources, which is called "potential danger to mother and child". The purpose of the service is to provide education on the addition of nutrients to reduce anemia. Based on the results of the activity, the delivery of material. The results of this activity are the participation of pregnant women during educational and simulation activities running smoothly, indicated by the activeness of pregnant women and attended by all pregnant women class participants and there is an increase in understanding of anemia by 50 %. The service was carried out on 23 June 2023 at Waonosari Polindes in the class of pregnant women. The method used was education and simulation in making soy milk and date pudding. Indonesia itself has an anemia prevention program for pregnant women by providing a minimum FE supplement of 90 tablets during pregnancy.

Human Immunodeficiency Virus (HIV) is a virus that weakens the immune system. HIV in pregnant women is one of the major health problems that is of concern throughout the world. In this case report, a patient aged 38 years G3P2A0, gestational age 37-40 weeks with complaints of coughing, shortness of breath, weight loss, burning sensation in the mouth in the form of white lesions that almost fill the entire oral cavity. The patient has a history of glandular TB and has received treatment for 6 months in the past 2 years. On the physical examination of the patient, the general condition of the patient was found to be seriously ill, composure of consciousness, blood pressure 100/70 mmHg, pulse rate: 78x/I, respiratory rate: 20x/I, temperature: 36.8ºC, SpO2: 98%, body weight 40 kg and height 157 cm. On examination of the general status of the skin, a reddish rash in the form of small vesicles was found on the right and left arms, back, neck and head. In the mouth and throat, white spots were found in the oral cavity, from the sides of the tongue to the throat. Laboratory investigations showed decreased hemoglobin levels, electrolyte imbalance, hypoalbumin. Serological examination revealed HIV (+) reactivity. Investigation of a PA chest photo showed infiltrate spots at the apex of the left medial lobe. Patients diagnosed with Std IV HIV + oesophageal candidiasis + pulmonary TB + hypoalbuminemia + anemia were given non-pharmacological and pharmacological treatments.

Stunting does not occur in a short time, but is a long and repeated process of malnutrition starting from the womb. Efforts to prevent stunting can be done starting from adolescence. The health status of adolescents determines the quality of life as adults, especially adolescent girls. The most common health problem in adolescent girls is nutritional problems, namely anemia. Adolescent girls who suffer from anemia are at risk of becoming women of childbearing age with anemia, then becoming pregnant women with anemia, and even experiencing protein energy deficiency. The activity method is carried out by providing counseling using the Pocket Book on Anemia in the work area of ​​the Perumnas II Health Center to participants who attended as many as 30 Adolescent Girls. Community service activities have been carried out and have received a good response from adolescent girls. The pocket book distributed to participants functions as an effective tool to remind and reinforce the material that has been delivered during the counseling.

The maternal mortality rate is an indicator of health status and is one of the health problems in the world. Brebes Regency is one of the contributors to the highest maternal mortality rate in Central Java. In 2021, the Bumiayu Regional General Hospital contributed to the Maternal Mortality Rate in Brebes Regency by 15 cases. The purpose of this research is to be able to provide comprehensive midwifery care for Mrs. The research method used is qualitative descriptive research with a case study approach. The case study carried out is in the form of comprehensive midwifery care that examines pregnancy, childbirth, newborns, postpartum and family planning with Varney's 7-step midwifery management and SOAP. The results of the pregnancy were found to be anemia and CED, delivery by caesarean section, the newborn was normal, during the neonatal period physiological jaundice was found, then appropriate management was carried out so that it could be resolved, during the postpartum period no problems were found, the mother used MOW KB. The conclusion obtained was that care had been carried out in accordance with midwifery service standards and the problem of anemia and CED had not been resolved  

Anemia is a medical condition characterized by a low number of red blood cells or low hemoglobin levels in the blood, namely <12 mg/dl for women and <13 mg/dl for men, thereby reducing the capacity of the blood to carry oxygen to the body's tissues which can cause fatigue. and decreased physical endurance which affects daily activities. This study aims to determine the description of the anemia status of the community in Rahandouna sub-district, Poasia sub-district, Kendari city. The research design used is descriptive, using a cross-sectional approach. The sample in this study was 50 respondents with an age range of 15 to 50 years. The tool used in this study was easy touch to measure the hemoglobin levels of respondents which are an indicator of anemia. The results showed that respondents with low hemoglobin levels reached 14% and the rest were in the normal category. From the results of this study, it was concluded that the problem of anemia in this area was not significant enough.

Hemoglobin (Hb) is a protein that functions to transport oxygen and carbon dioxide in the blood. Anemia, caused by iron deficiency, can affect physical health and academic performance, particularly in adolescents and students. Factors such as diet, habits, and socio-economic status contribute to the incidence of anemia. Anemia can lead to fatigue, reduced concentration, and decreased physical endurance. Therefore, improving nutritional status is crucial to support health and academic achievement.

The problem of anemia in adolescents is still a fundamental problem in the world. Anemia is associated with insufficient food intake and low food quality. Factors that correlate with the incidence of anemia in adolescents both in urban and rural areas are age, sex, health status of toddlers (ARI, diarrhea, tuberculosis), physical activity, nutritional status, breakfast, and diet, parenting and so on. This study aims to determine the anemia in adolescents. This study is an observational analytical study with a cross sectional design. This research was conducted in February-March 2024 in Cinta Damai Village, West Tanjung Jabung Regency. The population in this study were all toddlers aged 12-18 years. A sample of 89 people was taken by total sampling technique. Data collection using questionnaire sheets. The data obtained were analyzed univariately, bivariately using chi square and multivariate tests. The results showed that there was a relationship between infectious diseases (p =), toddler diet (p =) and parenting style (p =) with anemia in adolescents because the p value < 0.05. There was no relationship between giving MP-ASI too early and anemia in toddlers with a value of p = 0.647 > 0.05. The results showed that there was a significant relationship between the incidence of anemia during pregnancy with breakfast (p = 0.003), diet (p = 0.001) and head circumference because the p value < 0.05. There is no significant relationship between the incidence of anemia during pregnancy and chest circumference in newborns at the Jambi Kecil Muaro Jambi Health Center in 2023 with p values of 0.001 > 0.05. The most dominant factor affecting anemia in toddlers is the diet of toddlers with a value of p = 0.001 with OR = 13.108. It is hoped that the results of this study can provide information and recommendations to conduct a series of counseling and counseling activities for mothers of toddlers to prevent and overcome the problem of underweight.

The purpose of this study is to improve the health status of families so that healthy and prosperous families are realized. The study was conducted by collecting all available data through interview techniques and physical and supporting examinations. Subjective data, especially on the main complaint, namely the mother said she was weak, dizzy, tired quickly, short of breath and pain in the waist and legs. And objective data, namely the mother's general condition was good, anemic conjunctiva and Hb levels of 9.2 g%. The results of the study are the need for immediate action and collaboration on Mrs. A with mild anemia in Aik Lengis Hamlet, Kuta Village with the result that in this case no collaborative action was taken because there were no indications and data to support the action. Has determined a midwifery care action plan for Mrs. A with mild anemia in Aik Lengis Hamlet, Kuta Village with the results of planning care based on actual diagnoses/problems and potential problems that can occur and evaluating the results of the actions that have been carried out on Mrs. A with mild anemia in Aik Lengis Hamlet, Kuta Village with the result that the care that has been given was successful as indicated by changes in the mother's Hb levels which were initially 9.2 g% to 10.8 g%.