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Yulianing Tyas P.S; Gumiarti Gumiarti; Syiska Atik M

Jurnal Rumpun Ilmu Kesehatan 2023 Pusat Riset dan Inovasi Nasional

Exclusive breastfeeding is giving breast milk without other additional food and drinks to babies aged 0-6 months. Coverage of babies receiving exclusive breast milk in 2021 in Indonesia is 56.9%. At the Andongsari Jember Community Health Center in 2021 the coverage of exclusive breastfeeding was 9.2%. This coverage has decreased compared to 2020, amounting to 48.9%. The aim of this research is to determine the determinant factors for exclusive breastfeeding at the Andongsari Community Health Center. The research design used is descriptive. The population used by mothers breastfeeding babies aged 6-24 months was 100 people, the sample was 80 people. The technique used was simple random sampling with a questionnaire measuring instrument. The research results showed that knowledge was good 83.8%, fair 11.2%, less 5%, favorable attitude 55% unfavorable 45%, positive perception 50%, negative 50%, family income below UMK 82.5%, above UMK 17.5%, moderate husband support 68.8% high 31.2%, and the role of health workers supports 68.8%, does not support 31.2%. Almost all mothers have good knowledge about exclusive breastfeeding, most have a favorable attitude, half have positive perceptions, almost all have family incomes below the UMK, most have moderate husband support and most of the health workers' roles are supportive. It is recommended that breastfeeding mothers be able to increase and apply their knowledge in exclusive breastfeeding.

Kolentina Hutajulu; Yasrida Nadeak; Marlina Simbolon; Friza Situmorang

Journal of Educational Innovation and Public Health 2023 Pusat Riset dan Inovasi Nasional

One of changes that occur in puerperal ( post- partum is involution . uterus Involution or uterine contraction is a process uterus back into shape before pregnant . Uterine involution can also be regarded as the return of the uterus to its original state or condition before becoming pregnant. There are several factors that affect uterine involution including postpartum gymnastics. early mobility for maternal mothers, Early breastfeeding initiation, nutrition status, psychological age and parity factors. Early initiation of breastfeeding ( Inisiasi Menyusui dini or IMD ) is a breastfeeding process immediately after birth for 1 h. The purpose of research is to study influence of implementation early breastfeeding initiation ( IMD ) on the maternal uterine involution in BPS flora. This type of research is the study cohort analytic design Prospektive. Population and sample in this research is maternal in BPS flora in 2013 with techniques samples is concecutive sampling . The variables studied in this research is dependent and independent variables ,dependent variable studied were uterine involution while independent variables were early breastfeeding initiation (IMD). Quantitative data analysis include univariable and bivariate analysis with using t test. The results showed that average Height of uteri Fundus on day 6 postpartum that give Early Breastfeeding initiation ( IMD ) is 10,54 cm with standard deviation of 1.103 cm while Height of Fundus uteri in mother don;t give IMD is 13.33 with standard deviation 1,129 . based on statistical tests found an average difference both of them is p value of 0.000 with 95 % CI 2.143 to 3.440. There is a significant fundus height difference between mother that give IMD and who does not in BPS Flora . Health workers, particularly midwife are expected to be able to perform delivery assistance with IMD.

Sri Yanti; Sri Winarni

Jurnal Praba : Jurnal Rumpun Kesehatan Umum 2023 STIKES Columbia Asia Medan

Efforts to increase breast milk production can be done by carrying out early and routine breast care, improving breastfeeding techniques, or by consuming foods that can affect breast milk production. Indonesia is a country that is rich in various types of plants which are useful as medicinal plants. Some of them are efficacious as lactagogums such as katuk plants, lampes, sweet fennel, thorn spinach, bidara upas, blustru, chicken dadap, bitter black cumin, moringa, jackfruit, patikan kebo, pulai, curcuma, turi, and young papaya. Black cumin is one of them. spices containing lactagogum. This spice is in the form of black seed grains which have been known for thousands of years and are widely used by the people of India, Pakistan and the Middle East to treat various diseases. This type of plant has been referred to as a medicinal plant in the early development of Islam (Trubus, 2012). Lactagogum is a drug that can increase or facilitate milk production. Synthetic lactagogum is little known and relatively expensive. This causes the need to look for alternative lactagogum drugs.

Dewi Safitri; Dewi Sartika Hutabarat; Sastiani Br.Ginting; Ayu Rosarita; Syahrin Sakinah

Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) 2023 LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Early Initiation of Breastfeeding is the process of a baby breastfeeding immediately after birth, where the baby is allowed to look for the mother's own nipple (not having the nipple offered). Early initiation of breastfeeding will greatly help in the continuation of exclusive breastfeeding (breast milk only) and the duration of breastfeeding. IMD has been shown to extend the duration of breastfeeding, increase the chances of a baby being breastfed in the first months of life, and can also contribute to increased exclusive breastfeeding. Babies who practice IMD also appear to interact more with their mothers and cry less (UNICEF, 2018; WHO, 2019 ). This type of research is analytical, namely the researcher will analyze the relationship between maternal knowledge and basic immunization provision, with a cross-sectional design, namely data on the mother's level of knowledge and basic immunization provision. The research was conducted at the Midwife Sri Wulandari clinic, S.Tr.Keb in 2023. The research was conducted April to June 2022. The population is relatively small, namely under 100 people. From the description above, the author used a total sampling technique, namely 52 mothers with 1 year old babies.

Mei Tri Janti Silalahi; Sri Rezeki

Jurnal Riset Ilmu Kesehatan Umum dan Farmasi (JRIKUF) 2023 LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

According to data from the Indonesian Ministry of Health in 2021, the presentation of exclusive breastfeeding to infants showed an improvement from the previous year, from 69.62% to 71.58%. However, most provinces have a percentage below the national average, including Gorontalo (52.75%), Central Kalimantan (55.98%), West Papua (58.77%), Riau Islands (58.84%), DKI Jakarta 65.63%, Aceh (66.66%) and North Sumatra (57.83%). (Monavia, 2021). This study aims to identify the relationship between oxytocin massage and smooth breastfeeding for postpartum mothers in Tomuan Village, Siantar Timur District, Simalungun Regency in 2023.Type of quantitative research with cross sectional design. This study was conducted on a sample of 20 postpartum. To measure the characteristics of the respondents used a data collection form, to measure oxytocin massage with the smooth expulsion of breast milk in postpartum mothers respondents used a questionnaire.Based on the relationship between oxytocin massage and smooth breastfeeding in postpartum mothers, a p-value of 0.000 (p<0.05) was obtained which indicated that there was a significant relationship between oxytocin massage and smooth breastfeeding in postpartum mothers in Tomuan Village, Siantar Timur District, Simalungun Regency . Thus Ho is rejected, the correlation strength (r) = 0.014.The relationship between oxytocin massage and the smoothness of breastfeeding in postpartum mothers in the Tomuan Village, Siantar Timur District, Simalungun Regency, a category that has done oxytocin massage. It is recommended for postpartum mothers to do oxytine massage optimally so that breastfeeding can flow smoothly in Tomuan Village, East Siantar District, Simalungun Regency    

Herlien Sinay

Jurnal ilmu Kesehatan Umum 2023 Asosiasi Riset Ilmu Kesehatan Indonesia

Stunting is a condition of failure to thrive in children due to chronic malnutrition that results in a child's height not in accordance with their age. Stunting is not only caused by one factor but by multifactors. This study aims to determine the relationship between maternal education level, maternal knowledge, exclusive breastfeeding, complementary feeding and family economic status with the incidence of stunting in Kelapa Dua Hamlet, Kairatu District, West Seram Regency. The research design used was cross sectional. This study consisted of 100 samples with probability sampling technique. Data analysis was performed with the Chi-square test. The results showed that there was a relationship between the incidence of stunting and the level of maternal education (p-value = 0.000), maternal knowledge (p-value = 0.000), exclusive breastfeeding (p-value = 0.001) and complementary feeding (p-value = 0.000). However, family economic status (p-value = 0.511) has no relationship with the incidence of stunting in toddlers in Kelapa Dua Hamlet, Kairatu District, West Seram Regency.

Mustapa, Dwi Indrawan; Purwanda, Sunardi; Ambarwati, Auliah

DINAMIKA HUKUM 2023 Universitas Stikubank

This research was conducted with the aim of finding out the arrangements for the death penalty for climbing pregnant women and knowing the legal reasons for having to fulfill special rights, for example pregnancy, childbirth and breastfeeding for female prisoners who are temporarily carrying out the waiting period for execution of the death penalty. The type of research used in this research is normative research. Normative legal research is more likely to describe law as a descriptive discipline. Law Number 1 of 2023 which has been passed as a new law provides information that the implementation of the death penalty refers to Article 98 of Law Number 1 of 2023 which stipulates that capital punishment is punishable by an alternative which is only permitted to be released after a request for clemency for convicts who are rejected by the President. However, for pregnant women, women who are breastfeeding their babies, it turns out that it can be postponed until the women give birth, the women no longer breastfeed their babies, and also get a 10-year probation period for convicts to do good in prison. So there is a period of 10 years for the pregnant woman's desire to do good while being detained in prison.

Khoirunnisa M.J. Harahap; Mila Trisna Sari

Jurnal Riset Rumpun Ilmu Kedokteran 2023 Pusat riset dan Inovasi Nasional

Introduction: The incidence of stunting in North Sumatra Province reached 25.8% and is the 17th province with the incidence of stunting in Indonesia. Stunting in Medan City is spread across 63 urban villages and 20 sub-districts with the area that has the highest stunting rate is Medan Belawan Sub-district. Purpose: This research was conducted to assess the relationship between nutritional status, birth length and exclusive breastfeeding with the incidence of stunting in children aged 24-59 months in Medan Belawan District in 2023. Method: This research uses an observational study research design with a cross sectional design approach. carried out in the work area of ​​the Medan Belawan District Health Center. The sample was children aged 24-59 months who were recorded at the Medan Belawan District Health Center in 2023 who met the inclusion and exclusion criteria during the research period with a total sample of 44 people. Results: A total of 5 children (29.4%) with good nutrition experienced stunting, 11 children (68.8%) with poor nutrition experienced stunting and 11 children (100.0%) with poor nutrition experienced stunting with a p-value of 0.001. A total of 4 children (33.3%) with normal birth length experienced stunting and 22 children (59.4%) with short birth length experienced stunting with a p-value of 0.002. As many as 10 children (45.5%) who received exclusive breast milk experienced stunting and as many as 17 children (77.3%) who did not receive exclusive breast milk experienced stunting with a p-value of 0.030, which means p-value < 0.005. Conclusion: There is a significant relationship between nutritional status, birth length and exclusive breastfeeding with the incidence of stunting in children aged 24-59 months in Medan Belawan District in 2023.

Ramlan Nasution; Esrina Sinaga; Herawati Harahap

Jurnal Pengabdian Masyarakat Nian Tana 2023 Fakultas Ekonomi & Bisnis, Universitas Nusa Nipa

Community service for the D-III Nursing Study Program in Central Tapanuli, Medan Ministry of Health Polytechnic, is carried out in the form of education about community empowerment through balanced nutrition education as an effort to prevent stunting. The target of service activities is 40 pregnant women and mothers with early childhood children who are in the working area of the Hutabalang Community Health Center. The aim of this Community Service is to realize community service as one of the Tri Darma activities of higher education, increase the knowledge of pregnant women and mothers with early childhood regarding stunting and balanced nutrition and provide training on how to make naget as an effort to minimize the occurrence of stunting in the work area. Hutabalang Health Center, Lack of Knowledge about Stunting is caused by multi-dimensional factors and is not only caused by poor nutrition experienced by pregnant women and toddlers. Several factors that influence the incidence of stunting include maternal factors, home environmental factors, low food quality, inadequate feeding, food and drink safety, breastfeeding (breastfeeding phase), infection, political economy, health and health services, education, social and culture, agricultural and food systems, water, sanitation and the environment. Community service activities carried out in the working area of the Hutabalang Health Center, Badiri District, Central Tapanuli Regency by providing education to participants by means of lectures and question and answer/discussion, succeeded in increasing the knowledge of pregnant women and mothers with early childhood. Before the education was carried out, the level of knowledge in the good category was 40% and after the education was carried out it increased to 85%.

Devina Anggrainy Dencik

Jurnal Ventilator: Jurnal riset ilmu kesehatan dan Keperawatan 2023 Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Babies get their main nutrition, namely breast milk, through the breastfeeding process. However, in some cases breast milk can be low, one of the reasons is the mother's psychological condition. Mothers who feel unhappy, not calm, not relaxed, this will affect their breast milk. Hypnobreastfeeding is a relaxation technique to help smooth the breastfeeding process, by adding positive affirmations to your mind when you relax. Deep and regular relaxation makes the endocrine system, blood flow and other systems in the body function better because the endorphins produced by the mother will flow to the baby through breast milk and also make the baby feel comfortable and calm. Research objective: to determine the effect of hypnobreastfeeding on the smooth flow of breast milk in postpartum mothers at PMB Soraya Palembang. Method: This research uses a pre-experimental research design (one-group pre-post test design). The sampling technique used was total sampling with a total of 32 people. Univariate data analysis for homogeneity and bivariate tests used the dependent t test. The results of this study showed that respondents experienced an increase in breast milk production obtained from the pretest and posttest. The results of the dependent t test obtained a Z value of -2.129 and Asymp Sig of 0.001 < 0.005. The conclusion of this research states that there is an influence of the hypnobreastfeeding technique in expressing breast milk to the mother

Imelda Iskandar; Sendy Pratiwi Rahmadhani; Satiani Dalle; Rika Asriani

Nusantara: Jurnal Pengabdian kepada Masyarakat 2023 Pusat Riset dan Inovasi Nasional

Exclusive breastfeeding for babies in the first hour after birth and skin-to-skin contact between mother and baby are important factors in the beginning of the breastfeeding process where the baby will stay warm and the baby will get colostrum. However, the number of mothers who have breastfed their children in Indonesia is already high, namely 90%, but those who breastfeed exclusively for 6 months is still low at 20%. nutritional problems for toddlers and low achievement of exclusive breastfeeding as well as deaths under the age of 5, one of the causes of which is the lack of knowledge of mothers about the importance of giving exclusive breast milk, so it is necessary to carry out services aimed at increasing mothers' knowledge about exclusive breastfeeding in the Kassi-Kassi Health Center Working Area, Makassar City. The methods used in this activity are location survey, problem determination, formation of WhatsApp group classes, counseling and evaluation. The results of this activity. After carrying out online educational activities about exclusive breastfeeding, it was found that the activity increased pregnant women's knowledge about exclusive breastfeeding.

Ernawati Napitupulu; Isyos Sari Sembiring; Titin Suherni; Elnia Elnia; Rizky Andriani

Jurnal Ventilator: Jurnal riset ilmu kesehatan dan Keperawatan 2023 Stikes Kesdam IV/Diponegoro Semarang, Indonesia

BACKGROUND The exact incidence of infertility is not yet known with certainty, it varies greatly depending on geographical conditions, culture and social status of the country. Women who marry at an old age or mature and work actively will greatly affect a woman's fertility. It is estimated that around 2 million new infertile couples appear every year and this number continues to increase. It is estimated that a healthy couple will get fertilized within 1 year (Nuparma, 2017). Infertility data in the world according to the World Health Organization (WHO) and other reports estimates that 8-12% of couples experience infertility problems during their reproductive years. If eight percent of the global population figure is around 60-80 million couples who have not had children. OBJECTIVE To analyze the factors that influence the occurrence of primary infertility in couples of childbearing age at the Pegajahan Community Health Center, Pegajahan District, Serdang Bedagai District in 2023. METHOD chi square test p value < 0.05 means H0 is rejected and Ha is accepted, the statistical test results show a significant relationship. RESULTS: There is a significant relationship between age, menstrual cycle and no history of PMS and employment with the incidence of infertility and is a risk factor that has a significant influence on the incidence of infertility. Suggestions are given for research and for research sites and for educational institutions regarding exclusive breastfeeding and the implementation of IMD for newborn babies

Misdawati Misdawati; Nopalina Suyanti Damanik

Jurnal Ventilator: Jurnal riset ilmu kesehatan dan Keperawatan 2023 Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Service quality can be measured by comparing perceptions between the expected service and the service received and felt by the patient. Patient satisfaction is the level of patient feelings after comparing with his expectations. If a patient is satisfied with the value provided by a product or service, it is very likely that they will become a customer for a long time. The aim of this research is to analyze the relationship between service quality in the registration section and patient satisfaction for pregnant women at the Highlands Assistant Health Center, Highlands District, Binjai City in 2023. The type of research used in this study is analytical with a cross-sectional approach with the research sampling technique being non-probability sampling. or non-random sampling was carried out at PMB Tuti Khairina, Serdang Bedagai Regency with a sample of 32 KF 1 post partum mothers from February to May 2023. The results of the chi-square test obtained a p value = 0.001 (p <0.05). This means that there is The Relationship between Early Initiation and the Smooth Expenditure of Breast Milk in Post Partum KF 1 Mothers in PMB Tuti Khairina Serdang Bedagai Regency in 2023    

Sumarto Sumarto; Bercahaya Siregar; Muslika Sari; Parlin Edward; Yehezkiel Andersen +5 more

jurnal ABDIMAS Indonesia 2023 STIKes Ibnu Sina Ajibarang

Stunting is a growth and development disorder in children caused by poor nutrition and frequent and insufficient psychosocial stimulation infections. Stunting usually occurs due to several factors such as environmental factors, genetic factors, socioeconomic conditions, infectious diseases and exclusive breastfeeding. In DISKOMINFOTIK Bengkalis Regency, it is said that the prevalence of stunting in Bengkalis Regency in 2021 will reach 21.9 percent and drop to 8.4 percent in 2022. This is what caused us as KKN Bangun Kampung students at Riau University to realize the socialization of stunting in Wonosari Village as our flagship program. From these conditions, we as KKN Bangun Kampung Wonosari Village Students together with the head of the PKK and Posyandu cadres make every effort to provide knowledge about the understanding, symptoms and ways to prevent stunting to PKK mothers and members of the Wonosari Village posyandu cadre.  

Andre Irawan; Pika Noplianti; Fathia Berliani Surlianita; Indah Sepni Lestari; Yolinda Putri +6 more

jurnal ABDIMAS Indonesia 2023 STIKes Ibnu Sina Ajibarang

Stunting is a chronic nutritional condition caused by long-term malnutrition resulting in impaired growth and development in children. Toddlers are very susceptible to disease and nutritional disorders that can cause delays in growth and development. Stunted children have a higher risk of developing degenerative diseases and death. This community service was carried out in Gunung Kesiangan Village, Benai District, Kuantan Singingi Regency. The purpose of this community service activity is to 1) inform and educate the public about malnutrition and stunting in children, 2) increase public knowledge and understanding of stunting prevention, 3) increase awareness of mothers about child development from an early age. The benefit of this community service is changing people's behavior so they better understand what stunting is, its causes, and efforts to prevent it from an early age, even during pregnancy. The targets of this activity are pregnant women, breastfeeding mothers and children aged 0-2 years. The method used in community service activities is to distribute brochures about stunting to posyandu.

Gentina Gentina; Erin Padilla Siregar

The Journal General Health and Pharmaceutical Sciences Research 2023 LPPM STIKES KESETIAKAWANAN SOSIAL INDONESIA

Based on the results of Basic Health Research (Riskesdas) in 2013, the prevalence of stunting among toddlers in Indonesia was 37.2%. Then in 2018 there was a national decline to 30.8% (RI Ministry of Health, 2018). Thus, the incidence of stunting in Indonesia is still a problem that needs consideration because the national prevalence is still above the tolerance set by WHO, which is only 20%. The aim is to determine the relationship between pregnancy spacing and the incidence of stunting at the South Tapanuli Pargarutan Community Health Center in 2023. Stunting is caused by several factors, one of which is namely maternal factors (mother's knowledge regarding nutritional status, exclusive breastfeeding and complementary foods for breast milk. The type of research used in this research is quantitative research with a cross sectional research design. The sample for this study was 68 people. Based on the results of statistical tests using the Chi-Square test, it was found that p value is 0.042

Khoirotul Umi Mahmudah; Sri Kustiyati

Jurnal Inovasi Riset Ilmu Kesehatan 2023 Pusat Riset dan Inovasi Nasional

Background: Sixty percent of all maternal deaths occur during the postpartum period and 45% of these cases occur within the first 24 hours postpartum (WHO, 2018). Steps that can prevent postpartum bleeding management include active third stage, administration of uterotonics and early initiation of breastfeeding. Oxytocin hormone levels will increase in the third stage after separation of the placenta and when early initiation of breastfeeding is carried out because the pituitary gland releases the oxytocin hormone through the baby's stomping, touching and licking of the mother's skin so that it can prevent postpartum bleeding and speed up the expulsion of the placenta naturally. Objective: To determine the effect of early initiation on the number of post-delivery events at the Griya Mazaya midwifery clinic in 2023. Method: The research method uses analytical observational analysis with case control. The research design used a retrospective approach with a sample size of 44 respondents divided into 22 groups of respondents who did IMD and did not do IMD with a data processing test using Mann Whitney. Results: The results of Mann Whitney data processing showed a p value of 0.000, which means p value < sig (0.05) thus proving that there is a difference in the incidence of post-delivery bleeding. Mothers who did IMD had less bleeding than mothers who did not do IMD. Conclusion: Management of early initiation of breastfeeding immediately after the new baby is born can significantly reduce the rate of postpartum hemorrhage.

Aisyah Miftahu Rosyidah; Sri Kustiyati

Jurnal Inovasi Riset Ilmu Kesehatan 2023 Pusat Riset dan Inovasi Nasional

Background: The birthing process can affect breast milk production because it tends to cause lactogenesis to be slower. This is one of the factors why breast milk is not smooth at the beginning of the birth period. One treatment that can be done to facilitate breast milk production is by consuming Black Seed. Because black seed contains lagtogonum which functions to facilitate breast milk production. Objective: To determine the effect of giving black seed on the smooth production of breast milk in breastfeeding mothers at PMB Bidan Ning, Tawangmangu District. This research method uses a quasi-experimental method with a post test control group design. The research sample used accidental sampling, totaling 30 breastfeeding mothers on days 3-14 after giving birth who were divided into 2 groups, namely 15 control groups and 15 experimental groups. Results: The results of bivariate analysis using the Mann-Whitney test showed that the results for the black seed experimental group and the control group were p=0.000. Conclusion: There is a significant difference in the smoothness of breast milk between those given black seed and those not given black seed in PMB Bidan Ning, Tawangmangu District.

Marshanda Qisty Prabasari; Septi Tri Aksari; Norif Didik Nur Imanah; Ellyzabeth Sukmawati

Jurnal Mahasiswa Ilmu Kesehatan 2023 STIKes Ibnu Sina Ajibarang

Ineffective breastfeeding if not immediately handled can cause problems such as swollen breasts, nipple blisters, and mastitis in mothers. To prevent this, midwives play a role in overcoming the problem of breast milk that is not smooth, one of which is by providing complementary care in the form of the marmet technique. This study aims to determine the effect of marmet technique on the smoothness of breast milk production. This research is a qualitative research with case studies with data sources and data types using primary data obtained from interviews, examinations, and observations and secondary data obtained from relevant sources.  The implementation technique was carried out on Mrs. T by providing the marmet technique with a duration of approximately 20 minutes a day and conducting an evaluation after administration with the results known to have an effect on the smoothness of breast milk production.    

Sutrisna Pratiwi Simbuang; Enny Yuliaswati

Jurnal Inovasi Riset Ilmu Kesehatan 2023 Pusat Riset dan Inovasi Nasional

Background: The postpartum period is a very complex period experienced by a woman, especially for those who have given birth for the first time. The problem that we often encounter in the early postpartum period is the discomfort of mothers breastfeeding their babies because they are bothered by the presence of stitches for mothers who experience perineal lacerations. Objective: to determine the effect of VCO administration on perineal wound healing in postpartum women at Hospital Mother and Child Kasih Fatima Kotamobagu Methods: Quasi experimental design with post-test only with nonequivalent groups with Mann-Whitney test with 34 respondents and divided into 2 groups of cases and controls Results: Based on the statistical test output, it is known that the Asymp Sig (2-tailed) value is 0.000 <0.05, so it can be concluded that the hypothesis is accepted. Thus it can be said that there is an effect of VCO administration on perineal wounds with perineal wound healing. Conclusion: There is an effect of giving VCO with healing perineal wounds in postpartum women at RSIA Kasih Fatimah Kotamobagu, with this research it is hoped that VCO administration can be applied by health workers for wound healing, especially pernieal wounds.