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Non-communicable diseases (NCDs) are chronic health conditions that affect not only physical but also psychological well-being, including increased anxiety. Untreated anxiety can reduce quality of life and treatment adherence. Acupressure, as a form of complementary therapy, offers a safe and non-invasive approach to managing anxiety. This narrative review aims to evaluate the effectiveness of acupressure in reducing anxiety among patients with NCDs. Articles were searched using Google Scholar with keywords such as "acupressure", "anxiety", and various chronic diseases. Six studies with experimental and quasi-experimental designs were selected based on inclusion criteria, involving patients with cancer, chronic kidney disease, and osteoarthritis. The findings consistently demonstrated that acupressure reduced anxiety levels, whether performed by a therapist or self-administered, with commonly used points including ST36, LI4, and PC6. This review concludes that acupressure is an effective complementary therapy that can be incorporated into holistic care strategies for anxiety management in patients with NCDs.

Inflammation is a physiological response to tissue injury, infection, or harmful stimuli, characterized by redness, swelling, heat, and pain. However, excessive or chronic inflammation may lead to tissue damage and degenerative diseases. Long-term use of non-steroidal anti-inflammatory drugs is associated with gastrointestinal and cardiovascular side effects, highlighting the need for safer natural alternatives. Taro leaves (Colocasia esculenta) are traditionally used to treat swelling and wounds and contain bioactive compounds such as flavonoids, alkaloids, tannins, saponins, and triterpenoids with potential anti-inflammatory effects. This study aimed to evaluate the anti-inflammatory activity of ethanol extract of taro leaves and determine the most effective dose. An experimental study was conducted using male white mice (Mus musculus) divided into five groups: negative control (Na-CMC), positive control (sodium diclofenac), and three treatment groups receiving extract doses of 25, 50, and 75 mg/kg BW. Inflammation was induced by 1% carrageenan injection. The extract significantly reduced inflammation, with the highest inhibition (84.13%) observed at 75 mg/kg BW, comparable to diclofenac.  

Atherosclerosis, as the leading cause of cardiovascular disease, can be triggered by a high-fat diet that causes hyperlipidemia. Fern leaves (Diplazium esculentum) contain various bioactive compounds (alkaloids, phenols, flavonoids, terpenoids) with antioxidant and anti-inflammatory potential, which are suspected to inhibit the formation of atherosclerotic lesions. This study aims to determine the effect of administering fern leaf extract on the histopathological features of the aorta in Wistar rats induced by a high-fat diet. This laboratory experimental study used 25 male Wistar rats divided into five groups: (A) normal control, (B) negative control (high-fat diet), (C) positive control (high-fat diet + simvastatin), (D) treatment I (high-fat diet + fern leaf extract 600 mg/kgBW), and (E) treatment II (high-fat diet + fern leaf extract 1200 mg/kgBW). The treatment was administered for 21 days. On the 22nd day, the aorta was taken and processed into histopathological preparations using Hematoxylin-Eosin (H&E) staining. The number of foam cells was counted at 400x magnification. Data were analyzed using the One-Way ANOVA test followed by the Tukey test. There were differences in the number of foam cells between groups. The post-hoc test showed a significant difference between group B (high-fat diet) and all other groups (p<0.001). There was no significant difference between group E (extract 1200 mg/kgBW) and group C (simvastatin) (p=0.783), nor between group D (extract 600 mg/kgBW) and group C (p=0.075). Fern leaf extract (Diplazium esculentum) is able to reduce the number of foam cells in the aorta of Wistar rats induced by a high-fat diet.

A high-fat diet can cause hyperlipidemia, which is one of the main risk factors for atherosclerosis. Papaya flowers (Carica papaya L.) contain antioxidants that have the potential to inhibit the development of atherosclerotic lesions. This study aims to determine the effect of papaya flower extract on the histopathological features of the aorta of Wistar rats induced by a high-fat diet. The study design is a posttest only-trial group design. The study sample consisted of 25 male Wistar rats divided into 5 groups with treatment for 21 days. Group A received no treatment. Group B was given high-fat diet consisting of 3 mL of pork fat and 2 g of duck egg yolk. Group C was given high-fat diet and simvastatin 0.18 mg/200 gBW. Groups D and E were given high-fat diet and papaya flower extract 125 mg/kgBW and 250 mg/kgBW, respectively. The parameter used is the histopathological description of the aorta in the form of foam cell formation. The results showed that there were few foam cell in group A. Group B had many foam cells in the tunica intima and media of aorta. Group C, D and E showed a reduction in the number of foam cells. The administration of papaya flower extract (Carica papaya L.) was effective in inhibiting foam cell formation in the aorta of Wistar rats induced by a high-fat diet, with a better effect seen at a dose of 250 mg/kgBW, which was almost comparable to simvastatin.

The United States is often called the "land of the free" and the "land of opportunity," but its history is also rife with discrimination and injustice. This abstract explains how racism and inequality have shaped American society throughout the ages. This discrimination began with the system of slavery imposed on African Americans in the 17th century. This system not only took away their freedom but also placed them in a highly unfair situation. After slavery ended, discrimination persisted through Jim Crow laws, which allowed for racial segregation in areas such as education, transportation, and public services. Additionally, other groups such as Native Americans, Asian immigrants, and Latino communities also faced oppression. Native Americans' ancestral lands were confiscated, and they were forced to relocate to reservations. Asian immigrants experienced unfair treatment, including bans on entry and exclusion. Although the Civil Rights Movement of the mid-20th century successfully eliminated many laws that discriminated against, injustice persists. Systematic forms of racism are still evident in economic inequality, the way the law is administered, and disparities in access to education and adequate housing. Thus, American history is a story of the ongoing effort to realize the promise of justice for all its people, a process that continues to this day.

The management of material and labor costs at Gregors Barbershop is still manual and not formally structured, resulting in wastage of consumable materials, suboptimal labor utilization, and difficulties in determining service prices that align with the expected profit margins. Material costs, such as hair gel, tissues, disposable razors, and alcohol/disinfectants, are not recorded systematically, leading to frequent mismatches between stock and actual needs, while labor costs are calculated improvisationally without considering productivity and service targets. This activity aims to improve the ability of owners and employees to plan, control, and evaluate operational costs systematically, ensuring efficiency, resource optimization, and business profitability. The method uses an applied, hands-on approach, including the identification of partner needs, preparation of relevant training modules, direct operational mentoring, and evaluation with follow-up. The object of the activity is Gregors Barbershop in Batu Aji District, Batam City, which offers services such as modern men’s haircuts, classic shaves, shaving, hair treatments, and the sale of grooming products like pomade and hair oil. The results show increased efficiency in the use of consumable materials, more productive labor management, more systematic cost planning, and the ability to set service prices in line with costs and profit margins. It is recommended to implement a digital recording system and productivity-based incentives to ensure more accurate cost control, more efficient operations, and sustainable business profitability.

This article examines in depth the concept of protecting human dignity through the regulation of gaze and physical contact among mahram according to the Shafi‘i School of Islamic law. From an Islamic perspective, the preservation of dignity (ḥifẓ al-‘irḍ) occupies a highly fundamental position as part of the objectives of Islamic law, particularly in regulating social relations and family interactions. Although mahram relationships legally allow closer interaction, Islam continues to establish ethical boundaries to safeguard purity and moral values. This study is a normative legal research employing conceptual and normative-fiqh approaches, relying on primary sources such as the Qur’an, the Prophetic traditions (hadith), and classical as well as contemporary Shafi‘i jurisprudential literature. The findings indicate that the Shafi‘i School does not regard mahram relations as a sphere of absolute and unrestricted freedom, but instead provides clear regulations concerning gaze and physical contact. Visual interaction is permitted in a limited manner, restricted to certain parts of the body and subject to the condition that it does not provoke desire or potential moral temptation (fitnah). Meanwhile, physical contact is regulated more strictly and, in principle, is only permitted in situations of legitimate shar‘i necessity, such as medical treatment or emergency circumstances. Therefore, the regulation of gaze and physical contact among mahram in the Shafi‘i School functions as an instrument for protecting human dignity, preserving the sanctity of family relationships, and preventing behavioral deviations from an early stage.

Hypertension in the elderly requires long-term treatment to prevent cardiovascular consequences. Adherence to antihypertensive medication is crucial for blood pressure management. Adherence to antihypertensive medication is a crucial aspect in hypertension management. Poor adherence can lead to uncontrolled blood pressure, thereby increasing the risk of cardiovascular problems, including stroke, myocardial infarction, and heart failure. This study aims to determine the correlation between adherence to antihypertensive medication and blood pressure in the elderly at the Ronggo Husada Primary Inpatient Clinic in Malang. This study used a cross-sectional design. The cohort consisted of 52 geriatric patients with hypertension who consistently visited the Ronggo Husada Primary Inpatient Clinic in Malang. The sample consisted of 40 patients. The sampling method used was purposive sampling. Research factors included medication adherence and blood pressure. Data collection was conducted through a questionnaire. This study was conducted at the Ronggo Husada Primary Inpatient Clinic in Malang on November 6, 2025. Data processing used the Chi-square test. The analysis included univariate and bivariate analyses, using the Chi-square test. The results showed that more than 50% of elderly participants demonstrated moderate adherence to antihypertensive medication (18 individuals (45%). Nearly 50% of elderly participants suffered from stage I hypertension (14 individuals (35%), and stage II hypertension (11 individuals (27.5%). Statistical analysis using the Chi-square test showed a significant correlation between adherence to antihypertensive medication and blood pressure in the elderly, with a p-value of 0.000, which is below the alpha threshold of 0.05 (5%). Elderly individuals who demonstrated strong adherence had better blood pressure regulation compared to those with poor adherence. These results emphasize the importance of adherence to therapy in the management of hypertension in the elderly.    

The extract of Carica papaya L. leaves contains phytochemical compounds such as flavonoids, alkaloids, phenolics, and saponins that play a role in biological activities, including antioxidants, anti-inflammatory, analgesic, and modulation of the nervous system. This study aims to evaluate the effects of fresh papaya leaf extract on the central nervous system (CNS) and autonomic nervous system based on varying extract concentrations. The study used test animals with treatment groups consisting of negative control, positive control, and extracts at concentrations of 4%, 8%, and 16%. Parameters observed included parasympathomimetic (PSM), parasympatholytic (PSL), sympathomimetic (SM), sympatholytic (SL), analeptic effects (ANA), CNS stimulation (SSSP), CNS depression (DSSP), and muscle relaxation (RO). The results showed that the 16% concentration produced the highest PSM activity (46.82%) and dominant CNS stimulation (38.59%), while DSSP and RO decreased at higher concentrations. This phenomenon indicates that increasing the extract concentration does not always enhance CNS depression, but rather leads to stimulation. These findings support the potential of papaya leaf extract as a neuroprotective and multifunctional agent. Further research is needed to confirm its molecular mechanisms and clinical effectiveness as a phytotherapy candidate.

Long-term treatment adherence is critical for schizophrenia patients, yet non-adherence remains a significant global challenge, contributing to relapse, re-hospitalization, and increased healthcare costs. Understanding the underlying multidimensional factors is crucial for developing effective interventions. This systematic literature review aims to identify and categorize the dominant factors contributing to medication non-adherence among schizophrenia patients, based on current quantitative evidence (2019-2024). A systematic search of Google Scholar and PubMed targeted quantitative cross-sectional studies using the PICOST framework. Article selection followed PRISMA guidelines, and quality was assessed using the JBI Critical Appraisal Checklist. Seven articles were included in the final narrative synthesis. The synthesis confirms that non-adherence is multifactorial. Identified factors were categorized into three groups: (1) Patient-related factors (e.g., poor illness insight, feeling cured, treatment fatigue); (2) Treatment-related factors (e.g., medication side effects, therapy duration); and (3) System and social factors (e.g., low family support, stigma, poor therapeutic alliance). Non-adherence is a complex issue arising from the interplay of patient, treatment, and social factors. Low family support and poor patient knowledge consistently emerge as key determinants. Interventions require a holistic approach extending beyond pharmacotherapy, focusing on comprehensive psychosocial education for patients and families, active side-effect management, and strengthening the family's role in care.

Drug abuse constitutes a serious threat to public health, social stability, and national security. This study examines law enforcement mechanisms against drug abuse under Indonesian Law Number 35 of 2009 on Narcotics and evaluates preventive measures implemented to combat this phenomenon. Employing a normative juridical approach through a comprehensive literature review, this research analyses the implementation of both penal and non-penal approaches in addressing narcotics-related offences. The findings reveal that law enforcement practices predominantly emphasise punitive measures, despite legislative provisions accommodating rehabilitation for drug users. The dual approach integrating criminal sanctions with social and health services remains suboptimal due to institutional constraints, limited rehabilitation facilities, inadequate training for law enforcement personnel, and weak inter-agency coordination. Preventive efforts through education, family empowerment, school-based programs, community engagement, and media campaigns have been implemented but continue to face challenges, including social stigma and insufficient public awareness. This study recommends strengthening restorative justice implementation, expanding rehabilitation service capacity, and enhancing cross-sectoral collaboration to build societal resilience against drug abuse while ensuring that users receive appropriate treatment rather than mere criminalisation.

The right to health is a fundamental human right that remains inherent to prisoners. This study aims to examine the legal protection of prisoners' right to health care as regulated in Law Number 22 of 2022 on Corrections, as well as its implementation in correctional institutions. The research uses a normative juridical method with statutory and conceptual approaches. The findings show that Law Number 22 of 2022 formally guarantees prisoners' access to health services, including mental health care and special protection for vulnerable groups such as women, the elderly, and persons with disabilities. Key provisions in Articles 10, 11, 12, and 14 establish the state's obligation to provide adequate health services equivalent to community standards. However, in practice, the realization of this right faces several obstacles including: (1) overcapacity of correctional facilities exceeding 180% of ideal capacity, (2) limited medical personnel with many institutions lacking permanent doctors, (3) inadequate health facilities and medicine supplies, (4) complicated referral procedures causing delays in emergency treatment, and (5) insufficient budget allocation. Strengthening technical regulations, improving infrastructure, enhancing cross-sectoral collaboration, and implementing effective oversight mechanisms are essential to ensure effective protection of prisoners' health rights as mandated by the constitution and international human rights standards.

Background: Sexually Transmitted Infections (STIs) represent a global public health challenge. The increasing number of Sexually Transmitted Infection (STI) cases is a serious concern worldwide. A lack of education or minimal knowledge, along with risky behavior, contributes significantly to the high STI rates, particularly among the young age group. Purposes: The objective of this study is to conduct a comprehensive analysis of the major types of Sexually Transmitted Infections (STIs)—namely Gonorrhea, Hepatitis B, HIV/AIDS, Syphilis, and HPV—by identifying their risk factors and determining the most effective prevention strategies. Method:The researchers employed a literature review method. The data search process was conducted systematically on Google Scholar, limiting sources only to articles available in full text and having open access. Results: The literature review concludes that the factors of knowledge, attitude, behavior, and age significantly influence an individual's risk of contracting Sexually Transmitted Infections (STIs). Therefore, prevention efforts must be carried out comprehensively, encompassing promotive (awareness enhancement), preventive (prevention), curative (treatment), and rehabilitative (recovery) activities. Practically, this prevention must include sexual health education, adoption of safe sexual behavior, implementation of routine health checks (screening), and vaccination (specifically for Hepatitis B and HPV). Conclusion: Overall, controlling the spread of STIs requires active and collaborative roles from all parties—including the government, health workers, and the community. The main key to suppressing the spread and burden of STI diseases in the community is through improving appropriate sexual health education, improving access to health services, and periodic health screening.  

The use of laminated bamboo columns as alternative building materials has attracted increasing attention, particularly as a substitute for wood in construction. Bamboo lamination techniques enable the production of structural materials with tailored mechanical properties. Numerous previous studies have investigated the compressive strength of laminated bamboo short columns subjected to various treatments. This study aims to evaluate the compressive strength and failure patterns of laminated bamboo short columns under compression loading. The experimental program included physical and mechanical characterization of bamboo, followed by compression testing of laminated bamboo short columns with dimensions of 10 cm × 10 cm × 30 cm. Three treatment variations were examined: untreated laminated columns, epoxy resin–coated columns, and steel plate–reinforced columns. The results indicate that untreated laminated bamboo columns exhibited an average compressive strength of 28.044 MPa, with cracking concentrated at the top of the column. Epoxy resin–coated laminated bamboo columns achieved an average compressive strength of 28.774 MPa, showing crack formation distributed across several regions of the column. Steel plate–reinforced columns demonstrated the highest average compressive strength of 31.138 MPa, with failure localized in the region between the steel plates. These findings provide valuable insights into the effectiveness of different treatment methods in enhancing the compressive performance and failure characteristics of laminated bamboo columns.

Wheat has limited nutritional content, therefore fortification with other ingredients is required to complement these nutrients, one of which is fortification with pineapple peel flour and chicken bones in noodle products. Thus, this study was conducted to investigate the impact of adding chicken bone and pineapple peel flours on the characteristics of wheat flour noodles, with the goal of developing a product enriched in fiber and minerals, and exhibiting acceptable sensory qualities. The research design used a completely randomized design (CRD) with 2 experimental factors, namely pineapple peel flour concentration (0%,3%,5%) and chicken bone flour concentration (0%,5%,10%) with triplicate replication. Based on the optimal treatment by Zeleny method, sample N1T3 emerged as the most favorable formulation. This sample exhibited the following chemical profile: a moisture content of 8.77%, an ash content of 4.52%, a protein content of 14.45%, a fat content of 1.52%, and a fiber content of 0.4%. Furthermore, sensory evaluation of Sample C yielded scores of 3.11 for color, 3.11 for aroma, 3.00 for taste, 2.89 for texture, and 2.89 for overall acceptance.

Rice is a staple food for nearly two-thirds of the world's population, including Indonesians. Rice generally has a high glycemic index (GI) and cannot be consumed by diabetics.  Pratanak rice has a low GI, so it is recommended for diabetics. The study aimed to evaluate the effect of parboiled rice on the amount of LAB (Lactic Acid Bacteria), pH, and SCFA (Short-Chain Fatty Acids) of diabetic experimental animals. The research method consisted of 6 groups of rats with groups 1 (Cr and Mg fortified parboiled rice), 2 (Cr, Mg and cinnamon fortified parboiled rice), 3 (nonfortified parboiled rice), 4 (ciherang rice), 5 (standard feed for healthy rats), 6 (diabetic rats). All groups of rats were adapted for 3 days with standard feed and treatment for 14 days. LAB, pH, and SCFA were analyzed, statistical tests using One Way Anova if significantly different, followed by DMRT test. Giving chromium, magnesium, and cinnamon fortified rice gave a significant difference in the amount of LAB, pH, and SCFA feces between the treatment group and the control group. Thus, pre-cooked rice fortified with Cr, Mg, and cinnamon has the potential to be a healthier food option for individuals with diabetes.

This study investigates how puzzle games affect the fine motor development of young children. This study uses a quantitative approach and a quasi-experimental design. The study involved 30 children aged between 4 and 6 years who were divided into two groups: an experimental group and a control group. The experimental group received an intervention in the form of puzzle-playing activities for four weeks, with an interval of two to three times a week. On the other hand, the control group did not receive any special treatment for routine learning activities. To collect data, standardized fine motor skills test instruments were used. These included eye-hand coordination, finger movement control, precision, and the ability to assemble and copy shapes. A t-test was used to analyze the data to determine the difference in results between the two groups. The results of the study showed that the experimental group and the control group differed significantly. Compared to children who did not receive treatment, children who were involved in puzzle-playing activities showed greater improvement in all fine motor indicators. The results show that puzzle games can be used effectively as a learning tool to help the fine motor development of early childhood develop well.

The purpose of this study was to determine how puzzle games affect the problem-solving abilities of early childhood children. This study used quantitative methods and a quasi-experimental design. The study involved children aged 4 to 6 years from various early childhood education institutions (PAUD). Purposive sampling was used to collect samples. Data were collected through pre-tests and post-tests of problem-solving abilities and observations of children's behavior while playing puzzles. Logical thinking, creativity, concentration, focus, use of problem-solving strategies, and willingness to learn were all metrics used for assessment. To determine the differences in abilities before and after treatment, the collected data were analyzed statistically. The results of the study showed that puzzle game intervention improved children's problem-solving abilities. Children learned to identify problems, make plans for solutions, and work independently. In addition, it was proven that puzzle games as a learning medium were more effective with the help and guidance of teachers and parents. According to this study, puzzle games are an effective tool for developing the cognitive, social, and emotional abilities of early childhood.

Oil palm (Elaeis guineensis Jacq.) is an important plantation commodity that makes a significant contribution to Indonesia's economy. One of the macro nutrients that plays a role in supporting plant growth is potassium (K), which is involved in various physiological processes. The effectiveness of nutrient utilization is not only determined by the amount of fertilizer applied but also influenced by the application method, especially during the early seedling phase. This study aims to examine the growth response of oil palm seedlings to variations in KCl fertilizer doses and different fertilizer application methods during the pre-nursery phase. The experiment was arranged using a Factorial Randomized Block Design (RBD) with two treatment factors, namely KCl fertilizer dose and fertilizer application method, each with three replications. The KCl doses consisted of five levels, while the application methods included watering, broadcasting, and localized application (pocket). The observation data were analyzed using analysis of variance and followed by Duncan Multiple Range Test (DMRT) at a 5% level if there were significant differences. The results of the study showed that there was no interaction between the dose of KCl fertilizer and its application method on all observed oil palm seedling growth parameters.

Post-harvest handling of chili in Indonesia is still largely done manually, requiring a relatively long processing time and producing products with a non-uniform level of fineness. This condition impacts low production efficiency and the quality of processed chili. Therefore, the application of appropriate technology in the form of a chili flour machine is needed to increase production capacity and consistency. This study aims to analyze the effect of the number of blades and mesh size on the production capacity of a disk mill type FFC 15 chili flour machine. The research method used was an experiment with a factorial design, involving two variations in the number of blades, namely three and four blades, and three variations in mesh size, namely 0.5 mm, 1 mm, and 3 mm. Each treatment combination was carried out three times. The results showed that the number of blades and mesh size had a significant effect on the machine's production capacity. The best treatment combination was obtained by using four blades with a mesh size of 3 mm, which resulted in a production capacity of 6.84 kg/hour and a Composite Desirability value of 0.983. These results indicate that proper arrangement of machine components can increase the efficiency of post-harvest chili processing.