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Universities are educational institutions that have an important role in addressing various problems in rural areas by motivating, empowering, and broadening the perspectives of local communities. Through community service activities, universities can contribute to improving community skills and encouraging economic independence. This community service program aims to foster an entrepreneurial spirit among female farmers in APK Bandung Village, Selupu Rejang District, through training and assistance in producing pineapple-flavored papaya jam as a value-added agricultural product. The program was conducted in November 2025 and involved one partner, namely the Srikandi Women's Farmers Group (Kelompok Wanita Tani/KWT) 02 of APK Bandung Village. The implementation stages included socialization, product-making demonstrations, mentoring, monitoring, and evaluation activities. These stages were designed to enhance participants’ knowledge and practical skills in processing local agricultural commodities into marketable products. Out of 20 registered members of KWT Srikandi, 17 members attended and actively participated in the program. The results of the evaluation, based on questionnaires distributed to participants, showed that approximately 64.70% of the members demonstrated an entrepreneurial spirit. These findings indicate that the program contributed positively to increasing entrepreneurial awareness and encouraging the development of small-scale rural business opportunities among female farmers.

California papaya leaves (Carica papaya L.) are known to contain various active compounds that have the potential to stimulate appetite and boost metabolism, making them a promising candidate for development as a pharmaceutical formulation. This study aims to design a capsule formulation of California papaya leaf extract with appropriate excipients and to evaluate its ability to increase body weight through preclinical testing using a zebrafish (Danio rerio). The extract was obtained via maceration with 96% ethanol and formulated into capsules using the wet granulation method in four variations (F0–F3). Physical evaluations included organoleptic properties, flowability, angle of repose, loss on drying, disintegration time, weight uniformity, and stability testing using the cycling test method. The results indicated that all formulas met the physical requirements, with disintegration times of 3–4 minutes and loss on drying <15%. Formula F2 exhibited the most optimal physical characteristics; however, stability testing revealed a decline in physical properties after extreme temperature treatment. Efficacy tests showed a significant increase in zebrafish weight (p < 0.05), with F3 yielding the best results. A high survival rate (≥80%) suggests the formulation is relatively safe. In conclusion, California papaya leaf extract capsules demonstrate significant potential as an agent to promote weight gain.

Desa Manggihan in Semarang Regency is an environmental education tourism village supported by culinary MSMEs providing souvenirs. However, MSME actors faced challenges in business communication, including low self-confidence, suboptimal non-verbal communication, and an inability to deliver the Unique Selling Proposition (USP) of their products. This Community Service (PKM) activity aimed to improve verbal and non-verbal business communication skills, self-confidence, and elevator pitch techniques among partners. The method used was participatory training conducted on May 20, 2026, at the Manggihan Village Hall, involving three culinary MSME actors: producers of fried cheese cassava, crispy papaya floss, and peanut brittle (gula kacang). The activity stages included needs analysis, training, elevator pitch simulation, and qualitative descriptive evaluation through participatory observation. The results showed a significant improvement across all observed aspects. The MSME actors, who were previously passive and only mentioned prices/ingredients, became proactive, demonstrated better eye contact and open body language, and successfully delivered their product's USP briefly, clearly, and compellingly. This participatory training is proven effective in strengthening partners' business communication skills to better welcome tourists.

Bulay Village has an entrepreneurial spirit, with the idea of creating, developing, and managing new businesses and exploiting its papaya production potential. This innovation involves processing papaya chips (kreeyaa), which is expected to increase income. The goal of the PKM is to improve the community's economy by providing training and guidance on processing papaya into marketable products, motivating the community to generate creative ideas using existing resources, and establishing papaya chips businesses. The method used is partisipatory Action Research, an approach based on the assets, strengths, and potential of the community. Entrepreneurship mentoring seminars and training on making papaya chips (kreeyaa) in Bulay Village are expected to create jobs, develop community skills, and increase income by leveraging potential assets.

Local food innovation is not only focused on product development but also requires effective communication strategies to build positive perceptions and enhance market competitiveness. This study aims to analyze the implementation of innovation communication strategies by micro, small, and medium enterprises (MSMEs) in developing papaya-based chili chips as a flagship product in Nagori Karang Anyar, Gunung Maligas District, Simalungun Regency. The research employs a descriptive qualitative approach, focusing on the product innovation process, marketing communication patterns, and efforts to build product image amid competition in the local food industry. The findings indicate that innovation communication strategies play a crucial role in creating product differentiation through narratives of unique taste, utilization of local raw materials, and promotional strategies combining traditional methods and digital media. Papaya chili chips are positioned as a product that blends distinctive local flavors with a modern touch, attracting consumer interest and increasing the added value of papaya as a local commodity. This study emphasizes that the success of local food innovation depends not only on product quality but also on the ability of MSMEs to manage adaptive and persuasive communication strategies.

Papaya fruit (Carica papaya L.) is a tropical plant widely consumed as food and known to contain various bioactive metabolites with potential health benefits. The increasing interest in natural products as functional resources highlights the importance of reviewing the chemical characterization and health applications of papaya bioactive compounds. This article aims to systematically review the types of bioactive metabolites found in papaya fruit, the chemical characterization methods applied, and their potential applications in the health sector. This review was conducted through a literature study of relevant scientific articles, focusing on metabolite identification and biological activity evaluation. The results indicate that papaya fruit contains diverse bioactive metabolites, including flavonoids, phenolic compounds, alkaloids, saponins, terpenoids, and proteolytic enzymes. These compounds are commonly characterized using chromatographic and spectroscopic techniques. Several studies have reported that papaya bioactive metabolites exhibit biological activities such as antioxidant, antimicrobial, anti-inflammatory, and antidiabetic effects. This review suggests that papaya fruit has promising potential as a functional natural resource for health and pharmaceutical applications.

A high-fat diet can cause hyperlipidemia, which is one of the main risk factors for atherosclerosis. Papaya flowers (Carica papaya L.) contain antioxidants that have the potential to inhibit the development of atherosclerotic lesions. This study aims to determine the effect of papaya flower extract on the histopathological features of the aorta of Wistar rats induced by a high-fat diet. The study design is a posttest only-trial group design. The study sample consisted of 25 male Wistar rats divided into 5 groups with treatment for 21 days. Group A received no treatment. Group B was given high-fat diet consisting of 3 mL of pork fat and 2 g of duck egg yolk. Group C was given high-fat diet and simvastatin 0.18 mg/200 gBW. Groups D and E were given high-fat diet and papaya flower extract 125 mg/kgBW and 250 mg/kgBW, respectively. The parameter used is the histopathological description of the aorta in the form of foam cell formation. The results showed that there were few foam cell in group A. Group B had many foam cells in the tunica intima and media of aorta. Group C, D and E showed a reduction in the number of foam cells. The administration of papaya flower extract (Carica papaya L.) was effective in inhibiting foam cell formation in the aorta of Wistar rats induced by a high-fat diet, with a better effect seen at a dose of 250 mg/kgBW, which was almost comparable to simvastatin.

The extract of Carica papaya L. leaves contains phytochemical compounds such as flavonoids, alkaloids, phenolics, and saponins that play a role in biological activities, including antioxidants, anti-inflammatory, analgesic, and modulation of the nervous system. This study aims to evaluate the effects of fresh papaya leaf extract on the central nervous system (CNS) and autonomic nervous system based on varying extract concentrations. The study used test animals with treatment groups consisting of negative control, positive control, and extracts at concentrations of 4%, 8%, and 16%. Parameters observed included parasympathomimetic (PSM), parasympatholytic (PSL), sympathomimetic (SM), sympatholytic (SL), analeptic effects (ANA), CNS stimulation (SSSP), CNS depression (DSSP), and muscle relaxation (RO). The results showed that the 16% concentration produced the highest PSM activity (46.82%) and dominant CNS stimulation (38.59%), while DSSP and RO decreased at higher concentrations. This phenomenon indicates that increasing the extract concentration does not always enhance CNS depression, but rather leads to stimulation. These findings support the potential of papaya leaf extract as a neuroprotective and multifunctional agent. Further research is needed to confirm its molecular mechanisms and clinical effectiveness as a phytotherapy candidate.

This study examines the role of religious moderation as an ethical foundation for economic practices in sustainable community empowerment in Bintang Meriah Village. The research employs a descriptive qualitative approach with a participatory model through the Community Service Program (KKN) of the State Islamic University of North Sumatra. The values of religious moderation were integrated into various social, economic, and environmental programs, including anti-bullying campaigns, Islamic financial literacy, eco-print training, and the use of papaya leaf extract as an organic pesticide. Religious moderation serves as an ethical basis for fostering tolerance, social responsibility, and economic balance, while eco-theology strengthens ecological awareness and sustainability. The findings indicate an increase in community awareness of the importance of ethical and spiritual values in economic and environmental activities. The synergy between students, the community, and local government created empowerment practices that are not only economically beneficial but also uphold spiritual values and social sustainability.

This study aimed to evaluate the forage production characteristics of Japanese papaya (Cnidoscolus aconitifolius) as a potential feed source for ruminant livestock. The research employed a case study approach through direct field observations on four mature Japanese papaya plants naturally grown as living fences in Malang City. Measured variables included the diameter of the main branch, number and length of sub-branches, forage yield, and nutrient composition. Data were analyzed using correlation and simple linear regression to determine the relationship between plant structure and forage productivity. The results indicated that the diameter of the main branch showed a strong positive correlation with the number and length of sub-branches, as well as with forage yield and nutrient content (DM, OM, CP, CF, and EE). Regression analysis confirmed that larger branch diameters were consistently associated with higher forage production and better nutrient values. These findings suggest that the diameter of the main branch can serve as a reliable indicator for estimating the forage yield and nutritional potential of Japanese papaya, providing a practical tool for its use in sustainable ruminant feed management.

This Community Service Program (PKM) was implemented in Siantar Martoba, Pematangsiantar City, with the aim of enhancing the local economy through empowering farmer groups in optimizing backyard land. The program is a collaboration between Universitas Murni Teguh PSDKU Pematangsiantar, Politeknik Bisnis Indonesia, and the Food Security and Agriculture Office of Pematangsiantar City, attended by 15 farmers on July 4, 2025. The resource person, Henry Dunan Pardede, S.P., M.M., provided training on cultivating high-value crops such as California Papaya and Caplak Chili. The activities consisted of preparation, training, field assistance, and distribution of seedlings. The results showed an improvement in skills, entrepreneurial motivation, and more productive use of backyard land. This program also contributed to the achievement of SDGs point 1 (No Poverty), point 2 (Zero Hunger), and point 8 (Decent Work and Economic Growth) by strengthening the local economy based on agricultural potential. With a community-based approach, this program successfully increased food security, household income, and the sustainability of agricultural practices, while demonstrating the effectiveness of empowerment that can be extended to other areas facing similar challenges.

This community service article presents the implementation of the GELORA outreach and training program conducted in Sebanen Village, Jember, Indonesia, focusing on the promotion of low-cost and eco-friendly fermented feeds formulated from locally available agricultural residues such as papaya leaves, rice bran, molasses, and EM4. The program aimed to strengthen the capacity of smallholder catfish farmers and the village enterprise (BUMDes) through a series of integrated activities including a rapid needs assessment, hands-on training sessions, technical mentoring, and knowledge dissemination. As a result, participants demonstrated improved technical skills in household-scale feed formulation and fermentation, a stronger understanding of sustainable and circular economy principles, and an increased willingness to adopt environmentally friendly aquaculture practices. Moreover, follow-up mentoring groups were established to ensure program continuity and local innovation. This participatory model effectively combines community engagement with scientific evidence in aquaculture nutrition and is suitable for replication in other rural aquaculture development contexts.

Globally, 33% of all productive women aged 15-49 have anemia problems. Anemia is a condition where there is a deficit of erythrocyte cells, which is often found in all age groups, including women of childbearing age (WUS) and young women, namely 29% of young women and non-pregnant women and 38% of pregnant women have problems with anemia. This research aims to determine the effect of giving papaya fruit to young women who suffer from anemia on increasing hemoglobin in the work area of the Jabi Village Community Health Center, Batam City in 2024. This research was conducted using the Pre-Experiment method using the One Group Pretest Posttest Design approach. The sample for this research was 16 young women. The results of this study showed that the majority of young women experienced moderate anemia, as many as 10 young women (62.5%). After giving papaya to young women for 10 days, it was found that the majority of young women were not anemic, as many as 10 young women (62.5%). Based on the results of the Paired Sample T Test statistical test, show that the p-value is 0.000 < 0.05, so it can be concluded that there is an effect of giving papaya fruit to young women who experience anemia on increasing hemoglobin in the working area of the Jabi Village Community Health Center, Batam City in 2024. It is hoped that the Health workforce can minimize anemia in young women by giving them papaya.

Ketergantungan pada pestisida kimia dalam kegiatan pertanian berdampak negatif terhadap kesehatan manusia, lingkungan, dan menimbulkan resistensi hama. Pemanfaatan limbah organik seperti kulit bawang putih, kulit bawang merah, dan daun pepaya berpotensi sebagai bahan baku pestisida alami karena mengandung senyawa bioaktif yang bersifat insektisida. Tujuan dari program pengabdian masyarakat ini bertujuan untuk memberikan edukasi pembuatan pestisida alami dari bahan lokal di Desa Cibangkong, meningkatkan keterampilan masyarakat dalam mengolah limbah organik menjadi pestisida nabati, dan mendorong penerapan pertanian ramah lingkungan. Metode pada kegiatan dilaksanakan melalui sosialisasi bahaya pestisida kimia, pelatihan pembuatan pestisida alami berbahan kulit bawang putih, kulit bawang merah, dan daun papaya.

Women's empowerment is a program increasingly promoted by the government. When women are empowered, they will contribute in various sectors, including education, economics, culture, health, the environment, and so on. The presence of female entrepreneurs will shape the presence of women entrepreneurs in each region, bringing new breakthroughs to their respective business fields. The objectives of this community service activity are: 1) To provide knowledge about digital technology that women in Purwo Hamlet, Pasuruan Regency, can use to explore creative entrepreneurial ideas. 2) To provide mentoring and capital assistance for the most creative, original ideas, which will be developed with a systematic business plan and business control. The stages of this community service activity begin with planning, implementation, and evaluation. The results of this community service activity are: 1) The women of Purwo Hamlet, consisting of housewives, teenagers, and adult women who have graduated from school, are very enthusiastic about finding entrepreneurial ideas by opening several business applications on their mobile phones, then designing business ideas or business plans. They are also given modest capital rewards for original ideas. 2) The business plan submitted by the women of Purwo Hamlet related to the natural resources in Purwo Hamlet and what was implemented was young papaya fruit, which was planned to be made into shredded fruit targeting vegetarian consumers.

The use of chemical pesticides in modern agriculture in Indonesia has a negative impact on the environment and health. To address this issue, students from the 24th Community Service Program (KKN) of Raja Ali Haji Maritime University (UMRAH) held a training session on making plant-based pesticides from papaya leaves in Kota Baru Village, Bintan. This activity aimed to provide environmentally friendly and easy-to-apply pest control solutions to local farmer groups. The training involved agricultural extension workers from the Bintan Regency Food Security and Agriculture Office as resource persons. The results of this training are expected to increase farmers' knowledge and skills in utilizing papaya leaves as natural pesticides, reducing the use of chemical pesticides, and realizing more sustainable and environmentally friendly agriculture in Kota Baru Village. Despite obstacles in community participation, this activity succeeded in sparking farmers' interest in applying plant-based pesticides in their crop cultivation.

The agricultural sector plays a strategic role in ensuring national food security, particularly in rural areas where the majority of the population depends on agricultural production. Sememu Village, an agricultural-based community with rice and tobacco as its primary commodities, has faced recurring pest attacks in recent years. Conventional pest control methods in the area have primarily relied on chemical pesticides. However, excessive and prolonged use of these chemicals has resulted in serious problems, including pest resistance, environmental contamination, and potential health risks to farmers and consumers. This study aims to improve farmers’ knowledge and practical skills by introducing an alternative, eco-friendly approach through a training program on the production of botanical pesticides derived from papaya leaves (Carica papaya L.). Papaya leaves are known to contain bioactive compounds such as papain, chymopapain, alkaloids, terpenoids, and flavonoids, which exhibit natural insecticidal properties. The training activities consisted of initial observation, presentation of scientific and practical materials, hands-on practice in the preparation of botanical pesticides, and field testing on rice and tobacco plants. The findings demonstrated that the use of papaya leaf-based pesticides effectively reduced pest feeding activity and increased pest mortality rates, thereby minimizing crop damage. Importantly, this approach did not cause harmful effects on the surrounding ecosystem. The program highlights the potential of botanical pesticides as a sustainable solution for integrated pest management in agricultural villages, contributing both to environmental conservation and farmers’ welfare.

The agricultural sector plays a vital role in supporting Indonesia's economy, particularly in food provision and increasing rural household income. One of the promising horticultural commodities is California papaya (Carica papaya L.), known for its high productivity and short harvesting cycle. This crop is favored by farmers due to its stable market demand. However, to ensure the financial feasibility of this farming enterprise, a comprehensive financial analysis is necessary. This study aims to analyze the revenue, production costs, income, and financial feasibility of California papaya farming in Hinai Subdistrict, Langkat Regency. The research employed a descriptive quantitative method through a survey approach, with a purposive sample of 34 farmers. Data were analyzed using a farm income analysis approach, including the calculation of fixed costs, variable costs, total revenue, net income, and the Revenue/Cost (R/C) ratio. The results showed that the total production cost was IDR 590.734.000, while the total revenue reached IDR 1.970.685.000. The net income obtained by farmers amounted to IDR 1.379.951.000, with an average income of IDR 40.586.794 per farmer. The R/C ratio was calculated at 3.33, meaning that every IDR 1 spent on production costs generated IDR 3.33  in revenue. California papaya farming in Hinai Subdistrict is financially feasible, provides significant profit, and has strong potential to be further developed as a primary income source for horticultural farmers.

Dyslipidemia is a health problem characterized by impaired fat metabolism in the body, characterized by changes in blood lipid levels, either increasing or decreasing. This condition is generally seen through increased levels of total cholesterol, low-density lipoprotein (LDL), triglycerides, and decreased levels of high-density lipoprotein (HDL). This imbalance in the lipid profile, if persisted over the long term, has the potential to accelerate the formation of atherosclerotic plaque on artery walls, which can lead to cardiovascular disease. This study aims to determine the effectiveness of papaya leaf (Carica papaya L.) ethanol extract microcapsules in reducing cholesterol levels in white rats induced by a high-fat diet. The high-fat diet is formulated from a mixture of beef fat, eggs, and lard to increase cholesterol levels in a controlled manner. After the induction phase, the rats were divided into six treatment groups: a negative control group, a positive control group (simvastatin 0.36 mg), and three treatment groups with doses of papaya leaf ethanol extract microcapsules of 0.25%, 0.50%, and 0.75%. The treatment was given orally for 14 consecutive days. Total cholesterol levels were measured before and after treatment to evaluate the effectiveness of the intervention. The results showed that administration of papaya leaf extract microcapsules significantly reduced cholesterol levels. The 0.50% dose provided the most optimal effect, with a reduction reaching 77 mg/dL, greater than the simvastatin group. However, increasing the dose to 0.75% did not show a significant additional reduction effect, indicating an optimal dose-response point. Therefore, the 0.50% concentration can be considered the most effective dose and has the potential to be developed as an alternative natural cholesterol-lowering therapy. These findings also strengthen the potential use of papaya leaves as a bioactive source to support efforts to prevent and control dyslipidemia.  

Dengue Hemorrhagic Fever (DHF) remains a significant public health challenge in Indonesia, with the increasing prevalence of cases every year. One of the key methods of controlling the spread of DHF is to target the vector, Aedes aegypti mosquitoes, by eradicating their larvae. However, the widespread and continuous use of chemical larvicides has raised concerns regarding the development of mosquito resistance and environmental pollution. This community service activity aimed to provide students at Duta Karya Vocational High School with knowledge and practical skills to use natural, eco-friendly alternatives for controlling mosquito larvae, focusing on papaya seeds (Carica papaya) and alum as natural larvicides. The methods for this activity included interactive counseling, a demonstration on how to produce larvicides using papaya seeds and alum, and an engaging question-and-answer session. Thirty 12th-grade students from the Pharmacy class participated in this activity. The results revealed that the activity was highly effective in increasing the students' understanding and practical ability to independently create and apply natural larvicides. The students expressed a high level of enthusiasm and interest in the topic, actively participating in the discussions and demonstrations. As a result of this community service, the school has expressed interest in incorporating this activity into its School Health Unit (UKS) work program, which will further promote the use of natural, sustainable methods for controlling mosquito populations. The students, now equipped with the necessary skills, are ready to become "jumantik" cadres—community health volunteers responsible for monitoring and preventing mosquito larvae development. This initiative also raised awareness about utilizing organic waste, such as papaya seeds, to create valuable products for the prevention of DHF.