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The axiology of science is a branch of the philosophy of science that examines the values, goals, and orientations of scientific knowledge utilization. This article aims to philosophically analyze the concept of the axiology of science from Western and Islamic perspectives, highlighting their fundamental similarities and differences. This research employs a qualitative method, employing a literature review approach with descriptive-analytical and comparative methods. The results of the study indicate that in the Western philosophical tradition, the axiology of science has developed historically, from the search for the highest good in classical times to the tendency towards value relativism in the modern and postmodern eras, with human rationality as the center of value determination. Meanwhile, the axiology of science in Islam is rooted in monotheism as a metaphysical foundation, with revelation as the primary source of values ​​and reason serving as an interpretive instrument. Despite paradigmatic differences, both traditions affirm that science cannot be separated from moral dimensions and ethical responsibility. This article concludes that dialogue between Western and Islamic axiology is essential for building a scientific paradigm that is not only rational and progressive, but also moral, just, and oriented towards the welfare of humanity.

The mysteries of humanity are like the mysteries of nature: the more dimensions we know, the more we realize that there are still many unknown things. Humans are a symbol of the natural wonders created by God. There are people who have very attractive personalities and it is from their strong and noble personalities that they achieve success in society, become honorable people and are respected by society. Quraish Syihab in his book "The Science of the Qur'an" expresses Alexis Carrel's views regarding the difficulties faced in understanding human nature, according to which "humans have essentially devoted enormous attention and effort to understanding ourselves, even when we has quite a large nature. This research uses qualitative methods with a library research approach. The results of this research show that the nature of humans in the Islamic view is that humans were created to worship Allah Subhanahu Wa Taala, and the indicator of those who are said to believe and be devoted to Allah Subhanahu Wa Taala is that they believe in Allah Subhanahu Wa Taala, then they are patient in all forms. tests that Allah gives and be grateful if you are given favors, then advise each other on the truth.