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The Miana Coleus atropurpereus plant is a unique plant because it has so many varieties. The differences in these varieties can be seen from the very diverse differences in leaf color. Several studies have known about the active antimicrobial compounds of Coleus atropurpereus miana leaves, namely in the form of flavonoids, saponins, steroids, tannins, essential oils, eugenol, polyphenolic compounds, alkaloids, ethyl salicylate, calcium oxalate, rosmarinic acid compounds. In this study, Escherichia coli and Staphylococcus aureus bacteria were used using thick extracts that had been macerated using 96% alcohol. in this study it showed 8 mm at a concentration of 50%, at a concentration of 25% it showed a clear zone of 7 mm and at a concentration of 12.5% ​​it showed 6 mm. It can be concluded that the extract of Coleus atropurpereus miana leaves is weakly toxic to E. coli and not toxic to S. aureus bacteria..  

Papaya Carica papaya L. is a fruit commodity that has many functions and benefits as cooking, sweets, medicine, snacks. Secondary metabolite compounds found in Carica papaya L. papaya are flavonoids, polyphenols, quinones and tannins. It is known that falvonoid compounds can have antibacterial properties. In this research, it is hoped that papaya leaf stalk extract can act as an antimicrobial so that it can be used as first aid for diseases caused by E. coli bacteria.  This research used ingredients from 500 grams of papaya leaf stalk extract which had been macerated using 96% ethanol, to produce a thick extract. The thick extract was tested on NA growth media using E. coli bacteria. In this study, the clear zone produced at a concentration of 50% was 7 mm, at a concentration of 25% it produced a clear zone of 6 mm and at a concentration of 12.5%  it did not produce a clear zone.

The Miana Coleus atropurpereus plant is a unique plant because it has so many varieties. The differences in these varieties can be seen from the very diverse differences in leaf color. Several studies have known about the active antimicrobial compounds of Coleus atropurpereus miana leaves, namely in the form of flavonoids, saponins, steroids, tannins, essential oils, eugenol, polyphenolic compounds, alkaloids, ethyl salicylate, calcium oxalate, rosmarinic acid compounds. In this study, Escherichia coli and Staphylococcus aureus bacteria were used using thick extracts that had been macerated using 96% alcohol. in this study it showed 8 mm at a concentration of 50%, at a concentration of 25% it showed a clear zone of 7 mm and at a concentration of 12.5% ​​it showed 6 mm. It can be concluded that the extract of Coleus atropurpereus miana leaves is weakly toxic to E. coli and not toxic to S. aureus bacteria..  

Papaya Carica papaya L. is a fruit commodity that has many functions and benefits as cooking, sweets, medicine, snacks. Secondary metabolite compounds found in Carica papaya L. papaya are flavonoids, polyphenols, quinones and tannins. It is known that falvonoid compounds can have antibacterial properties. In this research, it is hoped that papaya leaf stalk extract can act as an antimicrobial so that it can be used as first aid for diseases caused by E. coli bacteria.  This research used ingredients from 500 grams of papaya leaf stalk extract which had been macerated using 96% ethanol, to produce a thick extract. The thick extract was tested on NA growth media using E. coli bacteria. In this study, the clear zone produced at a concentration of 50% was 7 mm, at a concentration of 25% it produced a clear zone of 6 mm and at a concentration of 12.5%  it did not produce a clear zone.

Plants have several ways to protect themselves from bacteria, one of which is by producing compounds that are toxic or repellent to bacteria. Compounds produced by plants are known as secondary metabolite compounds which originate from secondary metabolic processes. Several secondary metabolite compounds such as flavonoids, alkaloids, saponins, tannins, steroids and terpenoids are currently widely used as antibacterials. One of the plants that has the potential to be developed as a herbal medicine is kaffir lime leaves. Citrus hystrix is ​​the part of the plant most often used by the public. Both for cooking and traditional medicine purposes. In this research, it is hoped that lime peel extract can act as an antibacterial for Escherichia coli and staphylococcus aereus, so that it can be used as a herbal plant for diseases caused by these two bacteria. In the research, the concentrations used for each test bacteria were 50%; 25%; 12.5%. in observing S. aureus bacteria 1x24 hours with a concentration of 50%, the size of the inhibitory zone was 16 mm, the 25% concentration was 11 mm and the 12.5% ​​concentration was 9 mm. Meanwhile, E. Coli bacteria did not show any reaction to the heruk peel extract.

Plants have several ways to protect themselves from bacteria, one of which is by producing compounds that are toxic or repellent to bacteria. Compounds produced by plants are known as secondary metabolite compounds which originate from secondary metabolic processes. Several secondary metabolite compounds such as flavonoids, alkaloids, saponins, tannins, steroids and terpenoids are currently widely used as antibacterials. One of the plants that has the potential to be developed as a herbal medicine is kaffir lime leaves. Citrus hystrix is ​​the part of the plant most often used by the public. Both for cooking and traditional medicine purposes. In this research, it is hoped that lime peel extract can act as an antibacterial for Escherichia coli and staphylococcus aereus, so that it can be used as a herbal plant for diseases caused by these two bacteria. In the research, the concentrations used for each test bacteria were 50%; 25%; 12.5%. in observing S. aureus bacteria 1x24 hours with a concentration of 50%, the size of the inhibitory zone was 16 mm, the 25% concentration was 11 mm and the 12.5% ​​concentration was 9 mm. Meanwhile, E. Coli bacteria did not show any reaction to the heruk peel extract.