Kimia Medisinal dalam Terapi Kanker : Analisis Jalur Sinyal dan Interaksi Ligand-Target

Saeful Amin ; Alfi Nurul Aini ; Nandita Marsya Putri Utami ; Dini Aryani
Jurnal Riset Rumpun Ilmu Kesehatan 📅 2025 Vol 4, No 1 🔗 DOI: 10.55606/jurrikes.v4i1.4385
Abstract
Cancer is a chronic disease that poses a major challenge to global health, with increasing mortality rates. Although conventional chemotherapy has been the mainstay of treatment, this approach has limitations, including non-selectivity leading to severe side effects. Therefore, the development of longer-term cancer therapies, such as targeted therapy and immunotherapy, is of great importance. Medicinal chemistry plays a role in the discovery of bioactive compounds, including xanthones from Garcinia mangostana, which exhibit anticancer activity. This article reviews the contribution of medicinal chemistry to cancer therapy through the analysis of molecular signaling pathways and ligand-target interactions, as well as the use of computational techniques in drug design. With this approach, it is expected to improve the effectiveness of therapy and the quality of life of cancer patients.
Keywords
medicinal; chemistry; cancer; signaling; pathway
How to Cite

Saeful Amin, et al. (2025). Kimia Medisinal dalam Terapi Kanker : Analisis Jalur Sinyal dan Interaksi Ligand-Target . Jurnal Riset Rumpun Ilmu Kesehatan, 4(1). https://doi.org/10.55606/jurrikes.v4i1.4385

Saeful Amin; Alfi Nurul Aini; Nandita Marsya Putri Utami; Dini Aryani, "Kimia Medisinal dalam Terapi Kanker : Analisis Jalur Sinyal dan Interaksi Ligand-Target ," Jurnal Riset Rumpun Ilmu Kesehatan, vol. 4, no. 1, 2025.

Saeful Amin; Alfi Nurul Aini; Nandita Marsya Putri Utami; Dini Aryani. "Kimia Medisinal dalam Terapi Kanker : Analisis Jalur Sinyal dan Interaksi Ligand-Target ." Jurnal Riset Rumpun Ilmu Kesehatan, vol. 4, no. 1, 2025.

Saeful Amin; Alfi Nurul Aini; Nandita Marsya Putri Utami; Dini Aryani. "Kimia Medisinal dalam Terapi Kanker : Analisis Jalur Sinyal dan Interaksi Ligand-Target ." Jurnal Riset Rumpun Ilmu Kesehatan 4, no. 1 (2025).

Saeful Amin, et al. (2025) 'Kimia Medisinal dalam Terapi Kanker : Analisis Jalur Sinyal dan Interaksi Ligand-Target ', Jurnal Riset Rumpun Ilmu Kesehatan, 4(1). doi: 10.55606/jurrikes.v4i1.4385.

Saeful Amin; Alfi Nurul Aini; Nandita Marsya Putri Utami; Dini Aryani. Kimia Medisinal dalam Terapi Kanker : Analisis Jalur Sinyal dan Interaksi Ligand-Target . Jurnal Riset Rumpun Ilmu Kesehatan. 2025;4(1).

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