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Kajian Stabilitas Fisikokimia Antibiotik β-laktam: Implikasi terhadap Formulasi dan Penyimpanan
Abu Dzar Alghifary
; Nor Latifah
Inovasi Kesehatan Global
Vol 2
, No 3
(2025)
β-lactam antibiotics are a very important group of drugs and are most frequently used in the treatment of bacterial infections, both in healthcare facilities and for self-medication. The advantages of β-lactams lie in their effectiveness and broad spectrum of action. However, the development of pharmaceutical preparations containing β-lactams still faces significant challenges, particularly related to the physicochemical stability of these compounds. The reactive ring structure of β-lactams make...
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Hubungan Polusi Laut dan Perubahan Iklim terhadap Sebaran Resistensi Antibiotik
Adelia Ikrima
; Nadia Nadia
; Nor Latifah
Inovasi Kesehatan Global
Vol 2
, No 3
(2025)
Antibiotic resistance (AR) has emerged as a critical global public health concern, particularly due to the spread of antibiotic-resistant bacteria (ARB) and their genes in natural environments. The oceans, which host diverse ecosystems and serve as major food sources, are increasingly affected by ARB pollution, originating from human, agricultural, and industrial activities. Simultaneously, climate change (CC) exacerbates the situation by raising ocean temperatures, lowering pH, and altering mar...
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Peran Inovasi Kemasan dalam Menjaga Stabilitas dan Keamanan Produk Farmasi: Sebuah Literature Review
Nabilah Nabilah
; Ratna Habibah
; Nor Latifah
Jurnal Riset Ilmu Farmasi dan Kesehatan
Vol 3
, No 4
(2025)
Pharmaceutical packaging plays an important role in maintaining the stability, safety, and effectiveness of drug products during storage and distribution. Drug stability can be affected by various environmental factors such as temperature, humidity, oxygen, and light. Therefore, packaging innovation is a crucial strategy to extend the shelf life of drugs and maintain product quality, especially for sensitive preparations such as injections, transdermal patches, and biologics. This study is a lit...
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Studi Stabilitas Sediaan Suspensi Obat dalam Kondisi Suhu yang Berbeda
Muhammad Fadhli
; M. Chaidir Hafidz
; Nor Latifah
Jurnal Riset Ilmu Farmasi dan Kesehatan
Vol 3
, No 4
(2025)
Stability testing is an important step in the development of pharmaceutical products. This testing must be conducted before the product is manufactured, whether on an industrial or non-industrial scale. Currently, liquid formulations are experiencing rapid development, one of which is suspension. Suspension itself is a liquid formulation that contains undissolved solid particles dispersed in the liquid phase. To assess the stability of suspension, various evaluations are performed such as organo...
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Peran Material Pengemas Primer dan Sekunder dalam Menjaga Mutu Obat
Ghina Faiha
; Hana Salma Cantika
; Nor Latifah
Jurnal Riset Ilmu Farmasi dan Kesehatan
Vol 3
, No 4
(2025)
Packaging plays an important role in maintaining the quality, stability, and effectiveness of medicines, both in the form of pharmaceutical preparations and herbal products. This review article aims to analyze the role of primary and secondary packaging materials through literature studies from various relevant journals. The method used was a literature review of four selected national and international journals that discussed the influence of packaging on product stability, information effectiv...
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Uji Stabilitas Obat Sediaan Tablet: Prinsip, Pedoman ICH Q1, dan Parameter Kritis
Jannatun Nisa
; Nicky Saputra
; Nor Latifah
Jurnal Riset Ilmu Farmasi dan Kesehatan
Vol 3
, No 4
(2025)
This article provides a comprehensive review of drug stability testing, specifically focusing on tablet dosage forms. It elucidates the fundamental principles, the critical role of ICH Q1 guidelines, and essential parameters evaluated during stability studies, including physical, chemical, and microbiological aspects. The discussion covers various types of stability studies, standardized storage conditions, and the interpretation of results for determining shelf life and ensuring product quality...
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Review Jurnal : Perbandingan Uji Stabilitas Paracetamol dan Asetosal dalam Sediaan Tablet
Rakha Widyastama
; Sri Tami Dewi
; Nor Latifah
Jurnal Kesehatan dan Kedokteran
Vol 2
, No 3
(2025)
Drug stability testing is a critical aspect in the development and storage of pharmaceutical preparations to ensure the safety, quality, and efficacy of the product throughout its shelf life. Drug stability is influenced by various intrinsic and extrinsic factors, such as temperature, humidity, light, pH, and chemical and physical interactions. Stability evaluation includes long-term stability testing, accelerated stability, and in-use stability testing in accordance with ICH, WHO, or FDA guidel...
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Analisis Metode dalam Pengemasan Obat Primer dan Sekunder di Industri Farmasi
Fayza Nindya Nur’Assyfa
; Nia Kusumadewi
; Nor Latifah
Jurnal ilmu Kesehatan Umum
Vol 3
, No 3
(2025)
Optimization of primary and secondary packaging is crucial for the quality and efficiency of drug production. The drug packaging process consists of primary packaging that is in direct contact with the product and secondary packaging that provides additional protection and important information. This study aims to analyze various methods applied in pharmaceutical packaging to assess the effectiveness of Lean Manufacturing (VSM), Single Minute Exchange of Dies (SMED), and Overall Equipment Effect...
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Uji Stabilitas Fisik dan Kimia Sediaan Tablet Parasetamol dalam Berbagai Kondisi Penyimpanan
M. Jian Prayoga
; Maulida Maulida
; Maura Putri Ariqah
; Nor Latifah
Jurnal ilmu Kesehatan Umum
Vol 3
, No 3
(2025)
Paracetamol is a widely used analgesic and antipyretic drug in tablet dosage form. Ensuring the stability of paracetamol tablets is essential to maintain drug efficacy, safety, and quality during their shelf life. This study aims to evaluate the physical and chemical stability of paracetamol tablets stored under different temperature and humidity conditions. The review method used in this article involves analyzing published data from several sources, focusing on changes in physical appearance (...
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Artikel Review: Dampak Limbah Farmasi terhadap Lingkungan dan Upaya Pengelolaannya di Industri
Muhammad Rezky Wahyudi
; Hidayatur Rizky
; Ufaul Apriani
; Nor Latifah
Jurnal ilmu Kesehatan Umum
Vol 3
, No 3
(2025)
The pharmaceutical industry produces solid, liquid, and gaseous waste containing active pharmaceutical ingredients that pose serious environmental risks. These wastes can disrupt ecosystems and accelerate antimicrobial resistance. This systematic literature review examines pharmaceutical waste concepts, classifications, characteristics, and relevant regulatory frameworks. It also addresses ecotoxicological effects on aquatic and terrestrial ecosystems, antibiotic contamination and resistance, wa...
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