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Introduction: Dengue fever is a viral infection transmitted through the bite of infected female Aedes aegypti mosquito, caused by four dengue virus serotypes (DEN-1 to DEN-4), with clinical manifestations ranging from asymptomatic to severe disease and may be accompanied by warning sign. Concurrent infections, such as acute diarrhea, may worsen outcomes, particularly in children. Case Report: A nine-month-old female presented with a five-day history of intermittent fever and watery diarrhea. Additional symptoms included vomiting, lethargy, and decreased appetite. Physical examination showed a moderately ill appearance and sunken eyes. Laboratory findings revealed positive dengue IgM, negative dengue IgG, thrombocytopenia (22,000/µL), and hematocrit of 37%. The patient was diagnosed with dengue fever with warning sign and acute diarrhea. Management included intravenous crystalloid fluids, antipyretics, antibiotics, H2 receptor antagonists, and zinc supplementation. Conclusion: Dengue with warning sign and concurrent acute diarrhea in children increases the risk of morbidity and mortality. Early and appropriate management is essential to prevent disease progression and improve clinical outcomes.

Herpes zoster is a skin infection caused by the reactivation of the varicella-zoster virus, characterized by unilateral skin lesions corresponding to dermatome distribution and complaints of pain or itching. This disease is more common in adults and the elderly, especially in individuals with reduced immunity due to stress or work overload. A case was reported of a 40-year-old woman who worked as a nurse and came to a primary health care facility complaining of itching and red spots on her right breast area that had spread to the surrounding area two weeks before the examination and had worsened in the last few days. Physical examination revealed unilateral red skin lesions in a dermatomal pattern without crossing the midline of the body, consistent with the early phase of herpes zoster. Management was comprehensive, including medication, patient education about the disease and skin care, prevention of complications, and family support. A holistic approach is necessary to improve the success of therapy and the patient's quality of life.

Viral hepatitis is a systemic disease that primarily affects the liver and is characterized by a necroinflammatory process that plays a significant role in clinical and laboratory manifestations. Chronic hepatitis is defined as liver inflammation lasting more than six months, with persistent elevations in aminotransferases and characteristic histological features, and carries a risk of progression to cirrhosis and hepatocellular carcinoma. Chronic hepatitis C virus infection occurs due to an ineffective host immune response to the virus, allowing the infection to persist. The innate immune system, particularly type I interferon, plays a key role in the initial defense mechanisms against viral replication. Various antiviral therapies, such as interferon, nucleoside analogs, and nucleotide analogs, are currently available, which have been shown to reduce viral load and inhibit disease progression. Appropriate therapy is expected to prevent long-term complications in patients with chronic hepatitis.

Beef demand in Indonesia continues to increase, particularly during religious holidays. Bali cattle, one of the main sources of beef, face a serious threat from Jembrana disease, a viral infection that compromises the immune system and causes significant economic losses. This study aimed to determine the correlation between spleen weight, body temperature, and cycle threshold (Ct) values in Bali cattle following Jembrana virus inoculation. A correlational method was applied to eight female Bali cattle injected with Jembrana virus inoculum. Physiological changes in body temperature were monitored, followed by necropsy to assess spleen weight. In addition, Real-Time Polymerase Chain Reaction (RT-PCR) was performed before and after inoculation to detect viral presence and determine Ct values. Data were analyzed using SPSS with Pearson correlation tests. The results revealed a very strong positive correlation between spleen weight and body temperature, while a very strong negative correlation was observed between spleen weight and Ct values. These findings indicate that Jembrana virus inoculation leads to increased body temperature and splenic enlargement in Bali cattle, accompanied by a decrease in Ct values, reflecting higher viral loads. Therefore, the administration of antipyretics, anti-inflammatory drugs, analgesics, vitamins, and antibiotics prior to vaccination is recommended to reduce the risk of hyperthermia, splenic swelling, decreased Ct values, and secondary infections.

Currently, patients experiencing early symptoms of skin disease caused by the exanthema virus are unable to immediately consult a dermatologist due to the high cost and limited time available for specialists in hospitals. Therefore, the author needs to develop an expert system application that can address this issue. Through this application, users can consult with the system, much like an expert, to diagnose their symptoms and find solutions to their problems. This expert system is designed to provide answers based on whether the symptoms are correct or not, or to provide several recommended answer choices based on the symptoms. To diagnose skin disease caused by the exanthema virus, the author used the Case-Based Reasoning method. The CBR method is a weighting technique that compares new cases with previous cases. The diagnosis is based on data provided by the patient and expert, which is then analyzed using case-based reasoning and stored as a knowledge database in the expert system. Therefore, this expert system can help identify solutions for problems experienced by patients suffering from skin disease caused by the Exanthema Virus.

Background: Sexually transmitted diseases (STDs) are infectious diseases transmitted through sexual contact including vaginal, anal, oral intercourse and are caused by bacteria, viruses, and parasites, either directly or indirectly. Half of the 15-24 year olds contribute to sexually transmitted infections in the world. Objective: so that adolescents in Bangun Rejo Village are able to independently maintain their reproductive health to avoid sexually transmitted diseases. Method: Providing education about the prevention of sexually transmitted diseases in adolescents. The number of adolescents is 30 people. Population: all adolescents in Hamlet II, Bangun Rejo Village. Sample: all populations or total sampling. Data is frequency distribution. Results: before education, adolescents' knowledge about the prevention of infectious diseases was mostly lacking as many as 12 people (40%) and a minority of good as many as 7 people (23.3%), while after education, the results obtained were a majority of good as many as 16 people (53.3%) and a minority of less as many as 5 people (16.7%). Conclusion; There was an increase in knowledge after education about early disease prevention about sexually transmitted diseases in adolescents in Bangun Rejo Village. Suggestion: Provide counseling facilities for adolescents regarding sexually transmitted infections.

Sexually transmitted diseases (STDs) are infectious diseases transmitted through sexual contact including vaginal, anal, oral intercourse and are caused by bacteria, viruses, and parasites, either directly or indirectly. Half of the 15-24 year olds contribute to sexually transmitted infections in the world. So that adolescents in Bangun Rejo Village are able to independently maintain their reproductive health to avoid sexually transmitted diseases. Method: Providing education about the prevention of sexually transmitted diseases in adolescents. The number of adolescents is 30 people. Population: all adolescents in Hamlet II, Bangun Rejo Village. Sample: all populations or total sampling. Data is frequency distribution. before education, adolescents' knowledge about the prevention of infectious diseases was mostly lacking as many as 12 people (40%) and a minority of good as many as 7 people (23.3%), while after education, the results obtained were a majority of good as many as 16 people (53.3%) and a minority of less as many as 5 people (16.7%). Conclusion; There was an increase in knowledge after education about early disease prevention about sexually transmitted diseases in adolescents in Bangun Rejo Village. Provide counseling facilities for adolescents regarding sexually transmitted infections.

Tomato crop yields face significant threats from plant diseases, with existing deep learning solutions often computationally prohibitive for resource-constrained agricultural settings; to address this gap, we propose Efficient Disease Attention Network (EDANet), a novel lightweight architecture combining depthwise separable convolutions with hybrid attention mechanisms for efficient Tomato disease recognition. Our approach integrates channel and spatial attention within hierarchical blocks to prioritize symptomatic regions while utilizing depthwise decomposition to reduce parameters to only 104,043 (multiple times smaller than MobileNet and EfficientNet). Evaluated on ten tomato disease classes from PlantVillage, EDANet achieves 97.32% accuracy and exceptional (~1.00) micro-AUC, with perfect recognition of Mosaic virus (100% F1-score) and robust performance on challenging cases like Early blight (93.2% F1) and Target Spot (93.6% F1). The architecture processes 128×128 RGB images in ~23ms on standard CPUs, enabling real-time field diagnostics without GPU dependencies. This work bridges laboratory AI and practical farm deployment by optimizing the accuracy-efficiency tradeoff, providing farmers with an accessible tool for early disease intervention in resource-limited environments.

Cervical cancer is a malignant tumor that grows in the cervix caused by infection with the Human Papilloma Virus, acquired through sexual intercourse. Indonesia ranks 8th in the highest incidence of cancer in Southeast Asia, the highest prevalence of cancer is Yogyakarta Province where Sleman Regency ranks the highest IVA positive at 2.5% and Halis IVA at the Pakem Health Center is suspected of cervical cancer reaching 13 out of 22 positive IVA results. This achievement is still very low, because there is still low public awareness to carry out early detection of cervical cancer. To determine the relationship between attitude and behavior for early detection of cervical cancer. Quantitative research with a Case Control approach. A sample of 160 women with a proportional sampling technique. Data collection was in the form of filling out questionnaires online using Google Forms with chi square test data analysis and logistic regression. There was a relationship between positive attitude p-value=0.017 and OR of 3.462, women aged >35 years p- value=0.038, multipara parity p-value=0.007, with early detection behavior of cervical cancer. Parity provided a great chance of 7,038 times that women performed early detection behaviors of cervical cancer (CT 95%= 0.187-264,350). To improve early detection examinations, health workers can design health education and promotion models, increase educational socialization to cadres, the public and the community continuously and sustainably.

Penyakit Demam Berdarah Dengue (DBD) merupakan suatu penyakit yang disebabkan oleh gigitan nyamuk betina spesies aedes aegypti yang membawa virus dengue. Anak usia sekolah rentan terhadap penularan DBD sehingga sangat penting diberikan edukasi tentang penyakit ini. Metode edukasi yang tepat untuk anak usia sekolah salah satunya yaitu dengan permainan edukatif seperti permainan ular tangga. Metode permainan ini bisa memudahkan anak sekolah untuk menambahkan pengetahuan tentang penyakit DBD pada anak sekolah. Tujuan penelitian ini untuk mengetahui pengaruh edukasi permainan ular tangga tentang penyakit DBD terhadap tingkat pengetahuan pada anak sekolah. Jenis penelitian ini yaitu pre eksperimen dengan pendekatan one group pretest posttest design. Populasi adalah seluruh siswa-siswi sebanyak 193 orang. Teknik pengambilan sampel menggunakan proporsional random sampling yang ditetapkan berdasarkan rumus Slovin sehingga jumlah sampel sebanyak 66 orang. Instrumen pengumpulan data menggunakan lembar kuesioner. Analisis data menggunakan uji wilcoxon sampel t-test. Hasil penelitian pengaruh sebelum dan sesudah pemberian edukasi permainan ular tangga tentang penyakit DBD didapatkan p-value 0,000 (< 0.05). Kesimpulan penelitian ada pengaruh sebelum dan sesudah pemberian edukasi permainan ular tangga tentang penyakit DBD pada anak sekolah.

Dengue Hemorrhagic Fever (DHF) is an infectious disease caused by the dengue virus and transmitted through the bite of Aedes aegypti mosquitoes. In 2023, 48 cases of DHF were reported in the Kebun Lada Public Health Center area, reflecting a high incidence rate and limited medical resources in managing the cases. This situation emphasizes the need for an alternative solution that can support a fast and accurate diagnostic process. This study aims to develop an expert system for diagnosing DHF using the Case-Based Reasoning (CBR) method. CBR functions by comparing the symptoms experienced by patients with previous cases stored in the knowledge base, thereby producing relevant diagnostic recommendations. The proposed system is implemented as a web-based application using PHP as the programming language and MySQL as the database management system. The expected outcomes of this study are to assist medical personnel in reducing diagnostic time, improving the accuracy of decision-making, and increasing the effectiveness of health services in primary healthcare facilities. In addition, the system is designed to provide wider access for the community to recognize early symptoms of DHF, which can contribute to preventive actions and reduce the risk of severe complications. Thus, the developed expert system has the potential to become a practical solution to overcome the shortage of medical personnel and enhance public health awareness.

Dengue Hemorrhagic Fever (DHF) is an infectious disease caused by the dengue virus and transmitted through the bite of the Aedes aegypti mosquito. The high risk of dengue transmission is greatly influenced by the density of mosquito larvae which correlates with environmental conditions and community behavior. This study aims to describe the density level of Aedes aegypti mosquito larvae in the working area of the Gandus Health Center in Palembang City in 2025 through the measurement of House Index (HI), Container Index (CI), Breteau Index (BI), Larvae-Free Numbers (ABJ), and Density Figure (DF). The method used was descriptive observational with a purposive proportional random sampling technique on 100 households in three RTs. Data was collected through direct observation using checklist sheets. The results showed that the HI was 66%, CI was 44%, BI was 107%, and ABJ was only 34%, which indicates that the larval density is very high and far below the WHO standard (≥ 95%). The DF value is in the range of 7–9, reinforcing the finding of high vector density. This condition shows that the area is at high risk of dengue transmission. Interventions are needed in the form of regular mosquito nest eradication (PSN), increasing public education, and strengthening the role of jumantic cadres in sustainable vector control.

Community diagnosis is a strategic step that aims to identify fundamental problems in the community, determine problem priorities, and formulate appropriate solutions to overcome them. One of the identified health issues is a significant increase in cases of mumps (epidemic parotitis), an acute infectious disease caused by the mumps virus, a member of the Rubulavirus genus. This increase in cases was recorded in the Puskesmas work area from the beginning of the year to November 2024. This phenomenon raises concerns regarding the potential for widespread health problems at the community level. Therefore, this intervention activity was carried out with the hope of reducing the incidence of mumps in the Puskesmas work area.The methodology applied in this activity includes data collection through mini surveys, analysis of health determinants using the Blum Paradigm, determination of problem priorities through the Delphi method, and identification of root causes using a fishbone diagram. Based on the results of this analysis, the interventions implemented include counseling on mumps and preventive measures, as well as demonstrations of proper hand washing. The results of the intervention showed a significant increase in knowledge, where all participants (n=40, 100%) obtained a post-test score of ≥ 7, indicating a good understanding of the material presented. In the demonstration session, a number of participants were also able to demonstrate the steps for washing hands according to the correct procedure. From the results of the analysis, it was found that the increase in mumps cases in this area was closely related to community lifestyle factors. Therefore, this intervention is expected to not only increase community knowledge about mumps, but also encourage the implementation of clean and healthy living behaviors, especially in the practice of washing hands, as a preventive measure to reduce the number of transmissions and accelerate case handling.

This study aims to utilize data mining techniques, specifically the K-Nearest Neighbors (KNN) algorithm, to classify leaf diseases in sugarcane (Saccharum officinarum). Early and accurate detection of leaf disease types is a crucial step in prevention and control strategies, thereby reducing potential crop losses caused by pathogen attacks. Leaf diseases in sugarcane, such as leaf scald, rust, and mosaic virus, are known to affect photosynthesis, inhibit growth, and reduce the quality and quantity of sugarcane produced. The classification process in this study was carried out through image analysis of infected sugarcane leaves, where features such as color, texture, and shape were extracted using digital image processing techniques. The KNN algorithm was chosen because of its non-parametric nature, ease of implementation, and its ability to provide accurate classification results even with limited data size. The working principle of KNN is to determine the class of a new sample based on the majority class of its k nearest neighbors in the feature space, making it very suitable for the case of leaf disease image classification. In addition to building a classification model, this study also examines disease prevention strategies based on the identification results. These strategies include the use of disease-resistant sugarcane varieties, the implementation of appropriate planting patterns, land moisture management, regular plantation sanitation, and the measured and environmentally friendly use of pesticides or fungicides. Model performance evaluation was conducted using accuracy, precision, recall, and F1-score metrics to assess model effectiveness across various data scenarios. The results of this study are expected to not only contribute to the development of decision support systems for farmers and related parties but also support the application of artificial intelligence-based technology in the agricultural sector.

Pneumonia ialah penyakit Infeksi Saluran Pernapasan Bawah yang bersifat akut pada parenkim paru meliputi alveolus dan jaringan interential yang dikarenakan mikroorganisme seperti jamur, virus dan bakteri. Mikroorganisme yang masuk ke saluran pernafasan bagian bawah dapat mengganggu proses pernapasan serta membuat saluran pernapasan tidak berfungsi secara optimal, sehingga proses keluar masuk oksigen juga terhambat dan mengakibatkan gangguan pada pola napas. Beberapa permasalahan lain yang ditimbulkan dari pneumonia seperti adanya penumpukan sputum, otot bantu pernapasan, penurunan ekspansi thoraks dan juga nyeri dada. Dalam perawatanya, tenaga medis berperan dalam pemberian antibiotik selama 8 jam setelah pasien mengalami perawatan serta fisioterapi berperan dalam pemberian intervensi penyinaran Infrared, Chest physiotherapy, dan Myofascial release. Penelitian ini bersifat studi kasus yang mengangkat satu kasus pasien serta mengumpulkan data melalui proses fisioterapi. Intervensi fisioterapi dilakukan sebanyak 4 kali pertemuan di Rumah Sakit dr. Ario Wirawan, Salatiga dengan menggunakan Infrared, Chest physiotherapy yang meliputi Postural Drainage, Clapping, Vibrasi, Latihan Batuk Efektif, Pursed Lip Breathing dan Myofascial release. Setelah menjalani 4 kali terapi, diperoleh hasil kondisi pasien yang mengalami penurunan nyeri dada, penurunan tingkat sesak napas, peningkatan ekspansi thoraks, berkurangnya spasme otot bantu pernapasan dan retensi sputum.

Lungs are vital organs in the human respiratory system, responsible for fulfilling the body's oxygen needs. If the lungs experience health problems, it can have adverse effects on the human respiratory system. Common causes of lung diseases are usually due to inhaling air contaminated by dust, smoke, viruses, and bacteria. This study aims to compare the performance of two classification algorithms, namely Random Forest and Naive Bayes, in predicting lung diseases. The data used was obtained from the Kaggle website and processed using RapidMiner software. The attributes involved include smoking habits, pre-existing conditions, staying up late, exercise activities, age, and outcomes. Based on the test results, the Random Forest algorithm demonstrated the best performance with an accuracy of 93%, while the Naive Bayes algorithm achieved an accuracy of 87%. These findings indicate that the Random Forest algorithm outperforms the Naive Bayes algorithm in terms of lung disease prediction accuracy.

Bronchiolitis is an acute inflammatory injury to the bronchioles usually caused by a viral infection (most commonly respiratory syncytial virus). This condition can occur in people of any age, but severe symptoms are usually only seen in young babies.

Most people are exposed to sudden death as a result of viral hepatitis infection, especially at an advanced age, so we need to know the continuation of the disease until death in a sample of hospitals to know the differences in the services provided by those hospitals. The research aims to estimate a function for the Rayleigh distribution (RD) using several methods (maximum likelihood function, White, s, weighted least square) and choose the best method for estimation using the mean square error (MSE) and compare the survival rates of patients admitted to (Al-Kadhimiya, Al-Karkh, and Yarmouk) hospitals, The results of the research showed in the experimental aspect that the maximum likelihood method for all sample sizes is the best, followed by the weighted least squares method and finally the White method. In the applied aspect, on a sample consisting of (63) patients (liver cirrhosis + liver cancer) for the first quarter of 2025, it was found that their survival rate until death is (33%) for a time average of (2) months and (15) days.

The biggest challenge of today's health problems is still related to the human immunodeficiency virus (HIV) and Acquired Immunodeficiency Syndrome (HIV/AIDS). HIV and AIDS still have a negative stigma in society and are the cause of sufferers, still receiving bad treatment by their families. Every two minutes, one teenage girl or young woman is infected with HIV. In 2021, an estimated 250,000 teenage girls or young women are infected with HIV. The purpose of this community service is for teenagers and the community to recognize early on the signs of people with HIV and AIDS and to stay away from promiscuity which is one of the causes of the increase in HIV and AIDS. The implementation method is carried out by educating teenagers at the high school level aged 15-19 years and the community in Sannggaria Village. The implementation of education is carried out by providing lectures and video presentations explaining early sexual education. The results of the implementation of early sexual education for teenagers showed that 30 teenagers and 20 parents participated in the activity. The results of the knowledge evaluation showed that 90.75% of teenagers understood the material given. There are still teenagers who lack of understanding because in the middle of the process there were obstacles in absorbing information because the teenager had to attend other activities. Conclusion: adolescents' knowledge about HIV and AIDS is good but it needs to be emphasized in families to always supervise their teenagers.

COVID-19 is caused by the SARS-CoV-2 virus which infects the respiratory system and transmitted by droplets. This study aims to see the effect of administering Nigella sativa which has an immunomodulatory effect in reducing the clinical manifestations of COVID-19 disease by increasing the immune system. The method used is a literature review of five selected journals through a prism diagram flow from the PubMed, SpringerLink, and ScienceDirect electronic databases. Clinical manifestations of COVID-19 in patients decreased the length of patients’ hospital stay which become shorter in the intervention group compared to the control group. Nigella sativa has a positive response to increasing immunity. The immunomodulatory effect of NS is proven in increasing macrophage phagocytosis, immunoglobulin titer, lymphocyte ratio, and preventing T cell depletion and encouraging specific T cell proliferation.