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Diabetes mellitus is a chronic disease that requires long-term pharmacological therapy, increasing the risk of Drug Related Problems (DRPs). DRPs can affect the success of therapy, increase the risk of complications, and reduce the patient's quality of life. This article aims to identify the use of antidiabetic drugs, the characteristics of DRPs, and their clinical implications. The method used was a literature review of articles from 2016-2026 that are relevant to the analysis of DRPs in diabetes mellitus patients. The results of the study indicate that metformin is the most widely used antidiabetic drug, both as a single therapy and in combination. The dominant types of DRPs include drug interactions, inappropriate drug selection, inappropriate dosages, omissions from therapy, and use of drugs without indications. These DRPs can cause hypoglycemia, failure to achieve glycemic control targets, an increased risk of complications, and increased duration and cost of treatment. Based on the results of the study, it is concluded that DRPs remain a challenge in the management of diabetes mellitus therapy, requiring more optimal monitoring and an active role of pharmacists through medication review to improve the safety, effectiveness, and quality of treatment.

Logic gate learning is a fundamental topic in digital electronics; however, the learning process is often delivered theoretically with limited visualization of logic gate operations, making it difficult for students to understand the concepts. This study aims to design and develop an Augmented Reality (AR)-based learning media using a markerless approach with the 3D Object Tracking technique on Android devices. The application was developed using the Multimedia Development Life Cycle (MDLC) method, which consists of the stages of concept, design, material collection, development, testing, and distribution. The developed application provides three-dimensional visualization of logic gates, learning materials, interactive simulations, and quizzes. The application quality was evaluated based on the ISO/IEC 25010 standard, covering the aspects of Functional Suitability, Performance Efficiency, Usability, Compatibility, and Portability. The evaluation results showed that the application achieved a score of 100% in the Functional Suitability, Performance Efficiency, Compatibility, and Portability aspects. Meanwhile, the Usability evaluation obtained scores of 86,6% from respondents who had not previously studied logic gates and 89% from those who had, indicating that the application is categorized as highly feasible. Therefore, the developed markerless Augmented Reality-based learning media can serve as an interactive, engaging, and effective learning alternative for improving students' understanding of logic gate concepts.

The quality of Catholic Religious Education learning is an important aspect in shaping students’ faith, character, knowledge, and religious life skills. However, the learning process at SMK Negeri 1 Talibura still faces various challenges, particularly in the areas of spiritual attitudes, social attitudes, Catholic religious knowledge, and religious life skills. This study aims to describe the implementation of the Independent Learning Curriculum (Merdeka Belajar Curriculum) and its contribution to improving the quality of Catholic Religious Education learning at SMK Negeri 1 Talibura. The research employed a qualitative approach with a descriptive research design. Data were collected through observations, interviews, and documentation involving the principal, Catholic Religious Education teachers, students, and parents. Data analysis was conducted through data reduction, data presentation, and conclusion drawing. The results show that the implementation of the Independent Learning Curriculum has been carried out effectively through learning planning, learning implementation, learning assessment, and the Pancasila Student Profile Strengthening Project (P5). This implementation has had a positive impact on the learning process, outputs, and outcomes. Students demonstrated improvements in spiritual attitudes, social attitudes, Catholic religious knowledge, and religious life skills, as well as positive behavioral changes in their daily lives. The findings imply that the Independent Learning Curriculum can serve as an effective strategy for improving the quality of Catholic Religious Education learning in a holistic manner.

Background: Chronic Kidney Disease (CKD) patients undergoing long-term hemodialysis often experience anxiety due to therapy dependency, changes in health conditions, and uncertainty regarding the disease. Unresolved anxiety can reduce quality of life, comfort, and patient adherence to treatment. Therefore, non-pharmacological interventions are needed that are safe, easy to implement, and aligned with the patient's spiritual values. Mantram Tri Sandya has the potential to provide relaxation and psychological calm, thus helping to reduce anxiety. However, scientific evidence regarding the effectiveness of this therapy in hemodialysis patients is still limited, making this research crucial.  Purpose: The aim of this research is to determine the effect of the Tri Sandya mantra on reducing anxiety levels in CKD patients who are undergoing hemodialysis at the Buleleng Regency Regional Hospital. Methods: Pre-Experimental One Group Pre-Test & Post-Test research design with the Wilcoxon Signed Rank Test conducted at the Buleleng Regency Regional General Hospital. Data were collected using the HARS (Hamilton Anxiety Rating Scale) questionnaire sheet with Purposive Sampling technique with a sample size of 88 people. Results: The results obtained from this study were that there was a decrease in anxiety levels when given Mantra Tri Sandya therapy to CKD patients who were undergoing hemodialysis with a P value <0.001 (p<0.05). Conclusion: There is a significant effect of administering the Tri Sandy mantra on reducing anxiety levels in CKD patients who are undergoing hemodialysis at the Buleleng Regency Regional Hospital.

Road improvement projects require consistency between technical planning documents and field implementation to ensure that service quality, structural performance, construction time, and user safety are achieved. This article evaluates the conformity between planning and realization in the Pangkalan-Batas Jambi road improvement project in Rawas Ulu District, North Musi Rawas Regency. The study used a descriptive-quantitative evaluative approach based on field monitoring, project technical documents, comparative quantity analysis between contract and Contract Change Order (CCO), and identification of implementation constraints. The results showed that several work items changed during construction because initial planning data did not fully capture actual field conditions. Quantities increased for drainage excavation (+18.87%), roadbed preparation (+8.99%), aggregate class A base course (+12.51%), and AC-Base (+11.98%). Conversely, reinforced pipe culverts decreased (-58.33%), unsealed aggregate base/sirtu decreased (-43.50%), and tack/prime coat volume slightly decreased (-0.47%). The time schedule showed a minor delay of -0.13% in the first week but recovered in the second week, indicating effective field coordination. Main constraints included traffic interference, limited worker visibility, and equipment visibility. The study recommends more detailed site surveys during planning, stronger traffic management, stricter occupational safety implementation, systematic progress control, and routine post-construction maintenance to maintain road service life.

Background: The elderly are a vulnerable group requiring special attention, particularly regarding degenerative diseases like hypertension. In Melinggih Village, there are around 250 elderly residents, but participation in village activities is very low (only 57 are active). The main issues include limited information on degenerative diseases, a lack of skills in preparing traditional medicine, and weak cadre capacity in designing productive activities. Based on these conditions, this community service program (PKM) was implemented to improve the quality of life, health, independence, and productivity of the elderly, supporting the Indonesia Emas 2045 Vision and SDGs targets. Method: The research team partnered with the elderly group. Implemented solutions included education on degenerative diseases, training in making celery-based herbal drinks using Balinese local wisdom to lower hypertension, cadre mentoring, and elderly gymnastics. The program concluded with a comprehensive evaluation of participants' knowledge and skills. Results: Active activities were structured to increase elderly productivity: 1) Elderly gymnastics, educational activities, and active mentoring were conducted with the PKM team, cadres, and elderly in Melinggih Village regarding hypertension, resulting in increased knowledge and skills in managing elderly hypertension. 2) The elderly learned to make herbal drinks from celery. 3) Health cadres appeared active and collaborated well with the PKM team. Conclusion: Education on degenerative diseases, specifically hypertension, went well, successfully increasing cadres' and the elderly's understanding of their conditions to optimize health awareness. Training on traditional medicine preparation, specifically making celery drinks to lower hypertension, also progressed successfully.

Stroke is a neurological disorder caused by impaired blood flow to the brain, resulting in brain tissue damage and various functional impairments. One of the common problems experienced by stroke patients is sleep disturbance, which may be influenced by neurological deficits, limited physical mobility, pain, and post-stroke anxiety. Persistent sleep disturbances can delay the recovery process and reduce patients’ quality of life. The long-term use of sleeping medications may lead to adverse effects; therefore, safe and easily applicable complementary therapies are needed. This study aimed to determine the effectiveness of peppermint oil aromatherapy in improving sleep quality among stroke patients in the working area of Barebbo Community Health Center, Bone Regency. The method used was the implementation of complementary therapy through the administration of peppermint oil aromatherapy to stroke patients experiencing sleep disturbances. Sleep quality was assessed using the Pittsburgh Sleep Quality Index (PSQI) before and after the intervention. The assessment results showed that before the intervention, patients experienced poor sleep quality, characterized by difficulty initiating sleep, frequent nighttime awakenings, insufficient sleep duration, and daytime fatigue. After receiving peppermint oil aromatherapy, patients demonstrated increased comfort, reduced anxiety, improved ability to initiate sleep, and better overall sleep quality compared to their condition before the intervention. Therefore, peppermint oil aromatherapy was found to be effective in improving sleep quality among stroke patients and can be used as a complementary non-pharmacological intervention in nursing care.

Joint pain is one of the most common health problems among older adults and may reduce mobility and quality of life. Community self-survey data in Cepoko Village indicated that 55% of residents, particularly older adults, experienced joint pain complaints. One non-pharmacological intervention that can be applied is warm lemongrass foot soaking therapy known as SEHATI (Serai Hangat untuk Kaki). This community service activity aimed to improve elderly knowledge regarding self-management of joint pain and demonstrate warm lemongrass foot soaking therapy as a complementary treatment. The methods included health education, demonstration of warm lemongrass preparation, direct practice by participants, and evaluation through discussion and question-answer sessions. The participants were elderly individuals experiencing joint pain in Cepoko Village, Panekan District, Magetan Regency. The results showed that participants actively engaged in all activities, were able to explain the preparation steps of SEHATI, and understood the benefits of warm lemongrass foot soaking therapy for reducing joint pain. This program provides an easy, affordable, safe, and home-based complementary therapy alternative for elderly people.

The rapid advancement of digital technology has significantly transformed various aspects of human life, including the education sector. In the Society 5.0 era, educational institutions are expected to integrate digital technologies into learning processes to develop adaptive, innovative, and globally competitive human resources. This study aims to analyze digital technology-based learning innovations in improving educational quality, identify their potential benefits, and examine the challenges and strategies for optimizing their implementation. This research employed a qualitative descriptive approach through a literature review by analyzing relevant academic sources, including scholarly journals, books, conference proceedings, and other scientific publications. The findings indicate that digital learning innovations are implemented through the utilization of Learning Management Systems (LMS), Artificial Intelligence (AI), Augmented Reality (AR), Virtual Reality (VR), interactive learning media, blended learning, and flipped classroom models. These technologies contribute to enhancing learning effectiveness, expanding educational accessibility, increasing student motivation and engagement, and fostering essential twenty-first-century competencies. Nevertheless, several challenges remain, including digital inequality, inadequate technological infrastructure, limited digital competencies among educators, and concerns related to digital ethics and cybersecurity. Therefore, effective implementation requires comprehensive strategies, such as strengthening teachers' digital competencies, improving educational infrastructure, developing adaptive curricula, integrating innovative learning media, and promoting digital literacy and ethical awareness. These efforts are expected to support the development of a more adaptive, inclusive, and high-quality education system that aligns with the demands of the Society 5.0 era.

The high number of elderly people has led to various health problems that must be faced. However, there are still elderly people who are reluctant to carry out regular physical activity, so the health status and quality of life of the elderly also decline. Aims: This systematic review aims to identify the relationship between social cognitive theory (SCT) on physical activity in the elderly. Methods: This systematic review method approach is based on PRISMA. This systematic review examines several research articles from journal databases, namely PubMed and ScienceDirect, and obtained 13 articles in 2019-2024. The keywords used in the search are “Social Cognitive Theory”, “SCT”, “Physical Activity”, “PA”, and “Elderly”. The articles reviewed met the inclusion criteria, namely relevant article topics, original research articles in English, and publications in the last five years. The eligibility criteria were then assessed separately using the JBI Critical Appraisal Checklist tool.  Results: From a total of 13 articles reviewed, it can be concluded that the majority of articles explain how important the social cognitive patterns that elderly people must have in relation to the physical activity of the elderly, such as predicting the physical activity of the elderly, increasing the exercise behavior of the elderly, influencing the level of physical activity for people with chronic diseases, and adjusting physical activity with the abilities of the elderly. The higher an elderly person's social cognition, self-efficacy, encouragement, and social support to be able and willing to carry out physical activities in accordance with the elderly's abilities and physical condition. Conclusion: The social cognition of the elderly places more emphasis on the ability of the elderly to learn things around them, so that the elderly have self-efficacy, encouragement, and social support to do things in according to their goals and beliefs. Health workers in provide health services to the community, social cognitive theory can be used for alternative to increase the physical activity of the elderly. A personalized smartphone-based intervention based on SCT is highly effective for promoting physical activity in older adults.  

The quality of life and well-being of women in Indonesia can be measured through the Female Life Expectancy indicator. Data on Female Life Expectancy from 2022 to 2024 shows a nationally positive trend; however, a significant disparity persists across provinces, particularly between the Western and Eastern regions of Indonesia. The nation still faces challenges in ensuring an equitable quality of life for women, as evidenced by the national Female Life Expectancy (FLE) in 2024 at 74.21 years, which remains lower than ASEAN counterparts such as Singapore at 83.86 years. Furthermore, regional imbalances are reflected in the performance gap between D.I. Yogyakarta (77.4 years) and West Sulawesi (68.28 years). This study aims to analyze the effects of Women's Income Contribution, Access to Clean Water, the Number of Families Receiving Social Assistance, and Women's Mean Years of Schooling on Female Life Expectancy in Indonesia during the 2022–2024 period. The estimation method applied in this research is the Fixed Effect Model (FEM) via a quantitative panel data regression approach, spanning an observation area of 33 provinces (n=99). Based on the analysis, Female Life Expectancy is proven to be positively and significantly influenced by Women's Mean Years of Schooling and Access to Clean Water. These findings indicate that human resource quality and environmental conditions serve as dominant factors in driving up Female Life Expectancy. Therefore, government policy interventions should ideally focus on expanding educational access for women and ensuring the equitable distribution of clean water infrastructure.

This study examines the impact of implementing the Smart City Program in Grobogan Regency on the social and economic well-being of the local community. The research is motivated by local government efforts, supported by the Ministry of Communication and Information Technology, to apply the Smart City concept in order to improve public service quality, community welfare, and local economic growth. This study uses a qualitative approach with a case study method focused on Grobogan Regency. The method enables an in-depth analysis of the local context and the implementation of the program, which covers various social and economic dimensions. Data were collected and analyzed descriptively and inferentially to obtain a comprehensive understanding of the program’s impact. The results show that the Smart City Program has improved public service efficiency, strengthened local businesses through business ecosystem development, increased financial literacy, and enhanced the quality of life of the Grobogan community. However, challenges remain, particularly inequalities in access and digital literacy. The findings emphasize the important role of Smart Cities in sustainable development by promoting social and economic transformation, inclusive prosperity, capacity building, and cross-sector collaboration based on the real needs of the community in a gradual, adaptive, collaborative, and community-oriented regional manner.

Evolving tourism trends indicate a transition among tourists from merely visual recreation (hedonic) toward transformative travel (eudaimonic), which is oriented toward self-reflection and the search for meaning in life. Museum Topeng Cirebon holds significant potential for transformative tourism due to its mask collection that is rich in life philosophies. The urgency of this research is to analyze these transformative tourism experiences to support the quality of tourists' intellectual experiences and the sustainability of local culture. This qualitative research employed thematic analysis with purposive sampling techniques, involving 70 respondents who completed a Google Form questionnaire, which was further supported by interviews and a literature review. The results from the pre-visit phase showed that initial motivations were dominated by hedonic tourism at 37.1%. During the visit, a transformation occurred; tour guides acted as human catalysts in building narrative engagement (62.9%), and the chronological, philosophical flow of the masks sparked an awakening of consciousness for 80% of respondents. In the post-visit phase, eudaimonic impacts were experienced by 91.4% of respondents, including an expanded worldview (37.1%) and a commitment to becoming agents of cultural change (27.1%). However, operational challenges remain, including inconsistent opening hours and a lack of digital self-information facilities.

Nutritional problems among adolescents are increasingly associated with unhealthy dietary habits and low physical activity, contributing to the rising prevalence of overweight. According to the 2023 Indonesian Health Survey, overweight prevalence among adolescents ranges from 12% to 16.2%. This study aimed to develop Zea Coffee Tab, a functional beverage made from Robusta coffee and corn silk containing bioactive compounds, including caffeine and flavonoids, which may support metabolism and body fat oxidation. An experimental method with a Completely Randomized Design (CRD) was employed. The evaluated parameters included organoleptic tests (hedonic and hedonic quality) involving 30 semi-trained panelists, proximate analysis, and identification of bioactive compounds. Data were analyzed using the Kruskal–Wallis, Mann–Whitney, One-Way ANOVA, and Duncan’s multiple range tests. Three formulations were tested: F1 (30% Robusta coffee:70% corn silk), F2 (50%:50%), and F3 (70%:30%). The findings showed that F3 was the most preferred formulation, with an acceptance score categorized as “very much liked.” The product contained energy ranging from 319.20–324.26 kcal/100 g, protein 5.12–5.34%, fat 0.48–0.58%, carbohydrates 73.85–74.51%, moisture 9.12–9.66%, ash 2.10–2.32%, caffeine 182.45–205.86 mg/100 g, and flavonoids 4.28–6.03 mg/100 g. Zea Coffee Tab has the potential to serve as a healthy functional beverage for overweight adolescents. Further studies on shelf life and clinical effectiveness are recommended to support product commercialization.

Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels due to impaired insulin secretion, insulin action, or both. Uncontrolled diabetes can lead to various complications and decreased quality of life. Moringa oleifera leaves contain bioactive compounds, including flavonoids, vitamins A, C, and E, as well as selenium, which possess antioxidant properties and are believed to help reduce blood glucose levels. This study aims to determine the effect of Moringa leaf decoction on reducing blood glucose levels in patients with diabetes mellitus in Padaleu Village, Kambu District, Kendari City. The study employs a quantitative pre-experimental design using a one-group pretest-posttest approach. The population consists of 35 diabetes mellitus patients, with 17 respondents selected through purposive sampling. Blood glucose levels are measured before and after the administration of Moringa leaf decoction using a glucometer and observation sheets. Respondents receive 200 ml of Moringa leaf decoction daily for five consecutive days. Data analysis is conducted using paired statistical tests to determine differences in blood glucose levels before and after the intervention. The findings of this study are expected to provide scientific evidence regarding the effectiveness of Moringa leaf decoction as a non-pharmacological therapy for controlling blood glucose levels among diabetes mellitus patients. Furthermore, the results may contribute to nursing science development and serve as a reference for healthcare providers and future researchers in implementing complementary therapies for diabetes management.

Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that may persist into adulthood and affect academic, social, and occupational functioning. In adult patients, ADHD is frequently associated with an increased risk of Substance Use Disorder (SUD), raising concerns regarding the potential for misuse and dependence related to stimulant medications used in ADHD therapy. This study aimed to evaluate the effectiveness of pharmacotherapy for adult ADHD and to review the risk of stimulant misuse and dependence based on current scientific evidence. The method employed in this study was a literature review using data obtained from national and international journals indexed in Scopus, PubMed, and Google Scholar published between 2017 and 2026. The findings indicated that stimulant medications, such as methylphenidate and amphetamine, were effective in reducing the core symptoms of ADHD by increasing dopamine and norepinephrine activity in the central nervous system. Most studies reported that the use of stimulant medications at therapeutic doses and under medical supervision was not significantly associated with an increased risk of substance misuse or dependence. The risk of misuse was more commonly observed in cases involving non-medical use and inadequate clinical monitoring. In addition to pharmacological therapy, non-pharmacological approaches such as cognitive behavioral therapy (CBT) also contributed to improving treatment outcomes and patients’ quality of life. Therefore, the use of stimulant medications in adult ADHD patients may be considered relatively safe and effective when administered rationally, individually, and under appropriate medical supervision.

Complications of Diabetes Mellitus often arise and without being realized have developed to cause acute and chronic complications that make it difficult for DM sufferers to maintain their condition and will affect the condition of DM sufferers that impact the quality of life of sufferers. Consuming too many carbohydrates causes insulin in the body to work extra, so that the insulin's ability to work in the body will be reduced, which can cause blood sugar to rise. Nutritional therapy can be done by replacing carbohydrate intake with tubers that are low in glucose levels, one of which is Ganyong and pharmacological therapy through herbal medicines, one of which is sentalo leaf tea which is easily obtained and inexpensive. The objectives of this community service activity are to improve the knowledge, skills and quality of service of partners in the implementation of family posyandu related to DM. The method used is empowering posyandu groups through educational activities and training. The results of this activity show an increase in knowledge and skills of partners before and after the community service activity was carried out. And an increase in visits to the posyandu after the implementation of PMT using ganyong flour as the raw material.

Attention Deficit Hyperactivity Disorder (ADHD) is a neurodevelopmental disorder that may persist into adulthood and affect academic, social, and occupational functioning. In adult patients, ADHD is frequently associated with an increased risk of Substance Use Disorder (SUD), raising concerns regarding the potential for misuse and dependence related to stimulant medications used in ADHD therapy. This study aimed to evaluate the effectiveness of pharmacotherapy for adult ADHD and to review the risk of stimulant misuse and dependence based on current scientific evidence. The method employed in this study was a literature review using data obtained from national and international journals indexed in Scopus, PubMed, and Google Scholar published between 2017 and 2026. The findings indicated that stimulant medications, such as methylphenidate and amphetamine, were effective in reducing the core symptoms of ADHD by increasing dopamine and norepinephrine activity in the central nervous system. Most studies reported that the use of stimulant medications at therapeutic doses and under medical supervision was not significantly associated with an increased risk of substance misuse or dependence. The risk of misuse was more commonly observed in cases involving non-medical use and inadequate clinical monitoring. In addition to pharmacological therapy, non-pharmacological approaches such as cognitive behavioral therapy (CBT) also contributed to improving treatment outcomes and patients’ quality of life. Therefore, the use of stimulant medications in adult ADHD patients may be considered relatively safe and effective when administered rationally, individually, and under appropriate medical supervision.

A common health problem, especially in developing countries, is anemia. This is common among adolescent girls due to their lack of knowledge about anemia. This puts them at risk of developing anemia, particularly because menstruation is a contributing factor. Providing health education is expected to change behaviors toward a healthy lifestyle and contribute to preventing anemia among adolescent girls. This community service activity was held on May 26, 2026, at SMK Bhakti Indonesia Medika, and was attended by female students of childbearing age. The methods used included lectures, discussions, question-and-answer sessions, and sharing sessions. Pretests and posttests were used as evaluation materials to measure the increase in students' knowledge. The average pretest score was 7, while the average posttest score was 12, indicating a 5 point increase in knowledge about anemia among adolescent girls. The students demonstrated interest and enthusiasm during this activity. The results and conclusions of the e-booklet-based education program proved to be an effective alternative medium for increasing students' knowledge about anemia prevention. It is hoped that similar education can be implemented sustainably to improve the quality of healthy life in adolescent girls.

This study investigates the critical factors influencing job satisfaction among night shift employees at RSUD KHZ Musthafa Singaparna Tasikmalaya, given the inherent challenges of 24-hour hospital operations. Night shift workers are particularly susceptible to physical and psychological strain, which can elevate job stress and disrupt work-life balance, ultimately threatening their job satisfaction. The research employs a quantitative associative approach, utilizing Likert-scale questionnaires distributed to 75 night shift staff selected through purposive sampling. Data were analyzed using Multiple Linear Regression with SPSS. Instrument validation confirmed that all items were both valid and reliable. Partial regression results reveal that job stress exerts a positive and significant effect on job satisfaction (t = 3.106, Sig. = 0.003), while work-life balance also demonstrates a positive and significant impact (t = 1.815, Sig. = 0.044). Simultaneously, both variables together significantly influence job satisfaction (F = 10.121, Sig. < 0.001), with an RSquare of 0.419, indicating that 41.9% of the variance is explained by the model, while 58.1% is attributable to external factors. These findings underscore the importance for hospital management to actively manage job stress through targeted interventions and design equitable shift scheduling policies. Such strategies are essential to sustaining high levels of employee satisfaction, which in turn supports both staff well-being and the quality of patient care in a demanding healthcare environment.