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Diabetes Mellitus merupakan salah satu penyakit degeneratif dengan prevalensi yang terus meningkat, terutama pada kelompok usia lanjut. Kegiatan pengabdian kepada masyarakat ini bertujuan meningkatkan pengetahuan masyarakat mengenai pencegahan dan pengelolaan diabetes melitus melalui edukasi pola hidup sehat dan pemanfaatan tanaman obat. Kegiatan dilaksanakan di Desa Sambirata dengan sasaran ibu-ibu Posyandu Lansia. Metode yang digunakan meliputi penyuluhan kesehatan, pemeriksaan tekanan darah, pemeriksaan gula darah sewaktu, dan edukasi pemanfaatan tanaman obatantidiabetes. Sebanyak 44 peserta mengikuti kegiatan penyuluhan dan 71 peserta mengikuti pemeriksaan kesehatan. Hasil pemeriksaan menunjukkan 29 peserta mengalami hipertensi, 3 peserta memiliki kadar gula darah di atas normal, dan 50 peserta memiliki faktor risiko diabetes melitus. Kegiatan ini meningkatkan pengetahuan dan kesadaran masyarakat mengenai pentingnya pola hidup sehat serta penggunaan tanaman obat secara rasional dalam pencegahan diabetes melitus.

Diarrhea is a significant health issue that leads to a lot of illness and death, ranking third in Indonesia. The causes of diarrhea include inadequate environmental cleanliness, contaminated water sources, and insufficient knowledge in the community. When the community lacks knowledge, it can result in unsuccessful treatment outcomes. This ponder pointed to analyze how mother strengthening and family prosperity information influence loose bowels treatment in Karanganyar Kubu Karangasem Town, Bali. This think about executed a Pre Exploratory Plan, especially utilizing a one gather pre-post test arrange. The subjects of this ponder were moms chosen based on foreordained consideration and avoidance rules, centering on strengthening and family wellbeing. Data to assess the advancement of knowledge was gathered using questionnaires during the pretest, posttest I, and posttest II phases. Members included moms who were portion of family welfare activities in Karanganyar Kubu Karangasem town in Bali. Speculation testing was carried out to compare the comes about from the pretest to posttest I p <0.001, pretest to posttest II p <0.001, and posttest I to posttest II p <0.001, illustrating a noteworthy improvement in information after experiencing instruction through the CBIA strategy.

Diarrhea is a significant health issue that leads to a lot of illness and death, ranking third in Indonesia. The causes of diarrhea include inadequate environmental cleanliness, contaminated water sources, and insufficient knowledge in the community. When the community lacks knowledge, it can result in unsuccessful treatment outcomes. This ponder pointed to analyze how mother strengthening and family prosperity information influence loose bowels treatment in Karanganyar Kubu Karangasem Town, Bali. This think about executed a Pre Exploratory Plan, especially utilizing a one gather pre-post test arrange. The subjects of this ponder were moms chosen based on foreordained consideration and avoidance rules, centering on strengthening and family wellbeing. Data to assess the advancement of knowledge was gathered using questionnaires during the pretest, posttest I, and posttest II phases. Members included moms who were portion of family welfare activities in Karanganyar Kubu Karangasem town in Bali. Speculation testing was carried out to compare the comes about from the pretest to posttest I p <0.001, pretest to posttest II p <0.001, and posttest I to posttest II p <0.001, illustrating a noteworthy improvement in information after experiencing instruction through the CBIA strategy.

Leprosy is a chronic infectious disease caused by Mycobacterium leprae, an obligate intracellular bacterium that affects the skin, peripheral nerves, upper respiratory mucosa, and eyes. Type 2 diabetes mellitus (T2DM) is a comorbidity that can worsen the course of leprosy. The female patient, Mrs. D, aged 55 years came to the emergency room of Cut Meutia Hospital with the main complaint of red bumps accompanied by pain on the face, hands, chest, and back since 3 days ago and additional complaints such as fever, joint pain, and numbness and loss of feeling in the legs, weakness, frequent thirst, and frequent urination. Dermatologic status is obtained in the facial region in the form of erythema nodules with firm boundaries with numular size, multiple. Laboratory examination showed anemia and leukocytosis. The therapy given was MDT MB package, ferrous sulfate 1x325 mg and PRC transfusion 3 kolf. Complaints arose acutely after the patient resumed taking MDT (multidrug therapy) leprosy drugs which had previously been stopped for more than 3 months. Based on the time of onset of symptoms, history of leprosy treatment, and the manifestation of systemic inflammatory lesions with signs of neurotropism, it can be suspected that the patient is experiencing a type 2 leprosy reaction or Erythema Nodosum Leprosum (ENL).

The use of medicinal plants has been an important part of people's lives since the time of our ancestors. Before the advent of modern medicine, people used various types of plants to treat mild to severe illnesses, such as fever, cough, wounds, digestive disorders, and skin diseases. Inventory of medicinal plants plays a very important role in exploring the potential of existing natural resources, especially as an effort to support the development of traditional medicine. The purpose of this study is to identify the types of medicinal plants used by local communities in traditional medicine. The method used in this study is a descriptive method through direct surveys at the research location. The findings obtained in the field concluded that all types of plants mentioned in this study are very beneficial for the people of Duhiadaa District, because they can help in treating various types of diseases experienced by the community. The types of diseases that can be treated include hypertension, gout, stomach acid, cholesterol, kidney disease, diabetes, inflammation, cancer, wounds, diarrhea and digestive disorders.

Canker sores are an inflammation of the oral tissues, generally caused by bacterial and fungal infections. They can cause pain and discomfort and reduce the sufferer's quality of life. Treatment for canker sores has been dominated by synthetic drugs, but they are less popular among the public, especially children, due to discomfort and concerns about side effects. Therefore, we need safer and more easily accepted alternative treatments based on culturally derived materials. This study is to investigate the potential of pineapple and melon stems formulated in the form of gummy candy nanosimplicia as a complementary therapy in the treatment of canker sores. The research method was carried out through a literature review by collecting scientific articles from the PubMed, ScienceDirect, and Google Scholar databases, then analyzed using VOSviewer software to map emerging research trends and potential. The analysis results indicate that there are approximately 600 articles discussing the active metabolite content in pineapple and melon stems that have antibacterial and antifungal activity, as well as the development of innovative preparations such as gummy candy as a delivery medium for bioactive compounds. The implications of this study indicate that the combination of pineapple stem and melon nanosimplisia has the potential to be developed as a safe, attractive, and effective natural herbal candy product for the prevention and treatment of mouth ulcers, especially in children.

Penyakit Paru Obstruktif Kronik (PPOK) merupakan penyakit progresif yang ditandai oleh hambatan aliran udara yang tidak sepenuhnya reversibel, serta memiliki tingkat kepatuhan pengobatan yang rendah. Salah satu strategi yang dapat dilakukan untuk meningkatkan kepatuhan adalah melalui konseling oleh apoteker. Tujuan dari tinjauan literatur ini adalah untuk mengevaluasi pengaruh konseling apoteker terhadap tingkat kepatuhan pengobatan pada pasien PPOK. Pencarian data dilakukan melalui beberapa basis data, yaitu Google Scholar, Springer, ScienceDirect, dan PubMed dengan topik yang relevan. Hasil tinjauan menunjukkan bahwa konseling apoteker secara signifikan meningkatkan pemahaman pasien mengenai penyakit PPOK, manajemen eksaserbasi, dan teknik penggunaan inhaler yang benar. Selain itu, konseling juga berperan dalam mengurangi kecemasan, meningkatkan kepercayaan diri, efikasi diri, dan pengelolaan terapi yang lebih baik. Dengan demikian, implementasi konseling apoteker dalam praktik klinis sangat dianjurkan sebagai upaya meningkatkan kepatuhan pengobatan dan memperbaiki kualitas hidup pasien PPOK.

Pemanfaatan tanaman obat sebagai sumber agen neurofarmakologis alami semakin mendapat perhatian seiring meningkatnya prevalensi gangguan sistem saraf dan keterbatasan penggunaan obat sintetis. Salah satu tanaman yang berpotensi namun masih terbatas kajian ilmiahnya adalah Kesambi (Schleichera oleosa), yang secara tradisional digunakan untuk berbagai keperluan pengobatan. Penelitian ini bertujuan mengevaluasi pengaruh variasi konsentrasi ekstrak daun Kesambi terhadap efek neurofarmakologi, serta mengidentifikasi pola respons dosis dan konsentrasi paling efektif dalam memodulasi sistem saraf pusat dan otonom. Penelitian ini menggunakan desain eksperimental dengan hewan uji yang dibagi ke dalam kelompok kontrol dan kelompok perlakuan. Ekstrak daun Kesambi diperoleh melalui metode maserasi menggunakan pelarut akuades dan diberikan secara per oral pada konsentrasi 1%, 2%, dan 4%. Evaluasi efek neurofarmakologis dilakukan melalui skrining perilaku terhadap delapan parameter, yaitu parasimpatomimetik, stimulasi sistem saraf pusat, depresi sistem saraf pusat, simpatolitik, relaksasi otot, simpatomimetik, parasimpatiolitik, dan analeptik. Hasil penelitian menunjukkan bahwa ekstrak daun Kesambi menimbulkan variasi respons neurofarmakologis yang dipengaruhi oleh konsentrasi. Konsentrasi 4% memberikan efek paling dominan pada sebagian besar parameter, khususnya depresi sistem saraf pusat, relaksasi otot, dan modulasi sistem saraf otonom, sedangkan konsentrasi 2% menunjukkan efek stimulasi sistem saraf pusat yang optimal. Temuan ini menunjukkan potensi ekstrak daun Kesambi sebagai neuromodulator.  

Penyimpanan obat merupakan salah satu aspek penting dalam pelayanan kefarmasian di apotek yang berperan besar dalam menjamin kualitas, stabilitas, dan keamanan obat sampai ke tangan pasien. Khususnya pada obat-obatan yang termasuk kategori High Alert dan Look-Alike Sound-Alike (LASA), penyimpanan yang tidak sesuai standar dapat meningkatkan risiko kesalahan penggunaan obat (medication error) yang berpotensi menimbulkan efek samping serius hingga membahayakan nyawa pasien. Oleh karena itu, diperlukan sistem penyimpanan yang sesuai dengan standar yang berlaku. Penelitian ini bertujuan untuk mengocok penyimpanan obat High Alert dan LASA di Apotek Kaligelang, Kabupaten Pemalang, berdasarkan standar yang tercantum dalam Peraturan Menteri Kesehatan Republik Indonesia Nomor 73 Tahun 2016 tentang Standar Pelayanan Kefarmasian di Apotek. Penelitian ini menggunakan metode deskriptif dengan pendekatan observasional langsung dan wawancara terstruktur kepada tenaga kefarmasian yang bekerja di apotek. Evaluasi dilakukan terhadap aspek identifikasi, penandaan khusus, dan pemisahan fisik pada penyimpanan obat High Alert dan LASA. Hasil pengamatan Kesesuaian penyimpanan obat High Alert dan obat LASA di Apotek Kaligelang yang mengacu pada Permenkes RI No. 73 Tahun 2016, diperoleh bahwa sebagian besar aspek penyimpanan telah sesuai. Untuk obat High Alert, diperoleh Jumlah Total Prosentase 80% sudah sesuai, Sedangkan untuk obat LASA, diperoleh Jumlah Total Prosentase 75% sudah sesuai. Secara keseluruhan, tingkat kesesuaian penyimpanan obat High Alert dan LASA di Apotek Kaligelang mencapai rata-rata 77,5%, menunjukkan bahwa sistem pengelolaan obat berisiko tinggi di apotek ini telah berjalan dengan baik. Namun demikian, masih diperlukan beberapa perbaikan untuk meningkatkan keselamatan pasien (patient safety) serta mencegah terjadinya kesalahan pengobatan di lingkungan Apotek.

Drug storage is not only carried out in health facilities but can also be done independently by the community that consumes drugs, either as an emergency supply or leftover medication from previous use. Drug storage is often done without paying attention to the condition after the packaging is opened or understanding the drug's usage limit/Beyond Use Date (BUD). The community generally only looks at the expiration date/Expired Date (ED) on the drug packaging as a reference for safe drug use, and does not understand the safe usage limit for drugs after the primary packaging is opened. The purpose of this community service is to evaluate the community's knowledge and practices regarding the implementation of BUD/ED, as well as to provide education. This community service was carried out with an educational approach involving 21 people in Rejosari Village. This activity was carried out by distributing questionnaires to the community about the knowledge and practice of BUD/ED daily, then continued with the delivery of education using posters. The results of this activity indicate that the community has good knowledge of ED and BUD, but has not yet implemented ED and BUD in the storage and use of drugs independently.

Pulmonary tuberculosis (TB) remains a major public health problem in Indonesia. Despite the implementation of national TB control programs through the Directly Observed Treatment Shortcourse (DOTS) strategy, treatment success continues to face significant challenges, particularly related to patient adherence to anti-tuberculosis drug (ATD) therapy. Non-adherence to TB treatment can lead to treatment failure, disease relapse, and the development of drug-resistant tuberculosis, thereby increasing the overall burden of the disease.Treatment adherence in TB patients is influenced not only by medical factors but also by social and behavioral determinants. Family support plays a crucial role in encouraging patients to comply with treatment regimens by providing motivation, reminding medication schedules, and offering emotional support throughout the long duration of therapy. Patients who receive adequate family support tend to demonstrate higher levels of treatment adherence compared to those with limited support.In addition, the use of herbal medicine as a preventive and supportive health measure is common among the Indonesian population. Herbal medicine is often utilized to enhance immune function, reduce medication side effects, and improve patient comfort during TB treatment. However, the use of herbal remedies without proper medical guidance may lead to misconceptions regarding standard TB therapy.Therefore, it is important to examine the relationship between family support and the use of herbal medicine as preventive measures with treatment adherence among pulmonary TB patients in primary healthcare settings. Such evidence is expected to support a comprehensive family medicine approach and strengthen TB control programs in primary care services.