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Neonatal sepsis is a major factor contributing to morbidity and mortality in newborns. C-Reactive Protein (CRP) and leukocytes are laboratory tests used as indicators of inflammation. This study aims to determine the relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients. The research method used was an observational analytic with a cross-sectional approach. Neonatal sepsis at PKU Muhammadiyah Yogyakarta in the period 2021-2026 consisted of 30 samples using a total sampling technique. The distribution of respondents was dominated by male gender compared to female gender, who had a low birth weight <2,500 grams. Based on the study, normal CRP levels were found in 21 respondents, which was caused by a delay in increasing CRP levels. Leukocytes had high levels in 18 respondents. Leukocytes are an initial phase of examination in detecting inflammation that does not require a long time, have several different morphological types in detecting inflammation in the body. This study shows that the most dominant increase in leukocyte levels is found in eosinophils and neutrophils. Based on medical record data at PKU Muhammadiyah Hospital Yogyakarta, analysis using the Spearman correlation test yielded a correlation coefficient of 0.261 with a significance value of 0.164 (p > 0.05). The results showed no significant relationship between the studied variables, with a positive direction and weak correlation strength. The conclusion of this study is that there is no significant relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients.

Neonatal sepsis is a major factor contributing to morbidity and mortality in newborns. C-Reactive Protein (CRP) and leukocytes are laboratory tests used as indicators of inflammation. This study aims to determine the relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients. The research method used was an observational analytic with a cross-sectional approach. Neonatal sepsis at PKU Muhammadiyah Yogyakarta in the period 2021-2026 consisted of 30 samples using a total sampling technique. The distribution of respondents was dominated by male gender compared to female gender, who had a low birth weight <2,500 grams. Based on the study, normal CRP levels were found in 21 respondents, which was caused by a delay in increasing CRP levels. Leukocytes had high levels in 18 respondents. Leukocytes are an initial phase of examination in detecting inflammation that does not require a long time, have several different morphological types in detecting inflammation in the body. This study shows that the most dominant increase in leukocyte levels is found in eosinophils and neutrophils. Based on medical record data at PKU Muhammadiyah Hospital Yogyakarta, analysis using the Spearman correlation test yielded a correlation coefficient of 0.261 with a significance value of 0.164 (p > 0.05). The results showed no significant relationship between the studied variables, with a positive direction and weak correlation strength. The conclusion of this study is that there is no significant relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients.

The highest mortality cases during pregnancy until the postpartum period are caused by several factors such as hypertension, infection, bleeding, anemia and KEK. Data obtained from pregnant women at the Bumiayu Community Health Center in 2023 were 30 cases, in 2024 there was an increase of 183 cases and in 2025 from January to February there were 30 KEK cases (Bumiayu Community Health Center profile, 2025). The purpose of the study was to provide comprehensive midwifery care to pregnant women, childbirth, newborns, postpartum and family planning (KB) using the Varney and SOAP management approaches. The method used in this study is a qualitative descriptive method with a comprehensive case study approach. The results of the study of comprehensive midwifery care to Mrs. S found problems in pregnancy with KEK have been given management according to the mother's needs. In labor, newborns, postpartum to KB Mrs. S there were no complications. Conclusion Comprehensive midwifery care to Mrs. S with KEK has been carried out in accordance with Standard Operating Procedures with the condition of the mother and baby being good.  

Data from the 2020 LFSP (Long Form Population Census) recorded a maternal mortality ratio of 189 per 100,000 live births, while the infant mortality rate was recorded at 16.85 per 1,000 live births. The causes of maternal mortality were hemorrhage, preeclampsia/eclampsia, infection, prolonged labor, and miscarriage. Meanwhile, the majority of infant deaths were due to low birth weight, asphyxia, and infection at birth. Stunting remains a particular concern in Tegal City. Various measures have been taken, and the stunting rate has decreased to around 13.8% according to data from early 2025. This PKM is expected to increase public knowledge on caring for pregnant women, women in labor, postpartum women, and newborns, as well as preventing stunting in children, thereby reducing maternal and infant mortality rates. The methods used in this activity include health education and outreach with a promotive and preventive approach, targeting pregnant women and mothers with infants and toddlers. Community service was held on Wednesday, December 17, 2025, from 8:30 a.m. to 12:00 p.m. at the Boegenvil Health Center in Cabawan Village, Tegal City, with 53 participants. The results of this activity showed an increase in the level of knowledge of the participants, from 11 people with a good level of knowledge to 41 people after receiving counseling, with 3 participants still having a low level of knowledge.

Data from the 2020 LFSP (Long Form Population Census) recorded a maternal mortality ratio of 189 per 100,000 live births, while the infant mortality rate was recorded at 16.85 per 1,000 live births. The causes of maternal mortality were hemorrhage, preeclampsia/eclampsia, infection, prolonged labor, and miscarriage. Meanwhile, the majority of infant deaths were due to low birth weight, asphyxia, and infection at birth. Stunting remains a particular concern in Tegal City. Various measures have been taken, and the stunting rate has decreased to around 13.8% according to data from early 2025. This PKM is expected to increase public knowledge on caring for pregnant women, women in labor, postpartum women, and newborns, as well as preventing stunting in children, thereby reducing maternal and infant mortality rates. The methods used in this activity include health education and outreach with a promotive and preventive approach, targeting pregnant women and mothers with infants and toddlers. Community service was held on Wednesday, December 17, 2025, from 8:30 a.m. to 12:00 p.m. at the Boegenvil Health Center in Cabawan Village, Tegal City, with 53 participants. The results of this activity showed an increase in the level of knowledge of the participants, from 11 people with a good level of knowledge to 41 people after receiving counseling, with 3 participants still having a low level of knowledge.

Non-health facility deliveries remain a significant maternal health problem in rural areas, increasing the risk of complications for both mothers and newborns. Cigobang Village, Karang Tengah, Babakan Madang District, is one of the areas where home deliveries assisted by non-health personnel are still practiced. This community service activity was conducted through the Village Community Health Development (PKMD) program involving 103 respondents, there were 8 pregnant women (100%) who still planned to give birth at home assisted by non-health personnel. The objective of this activity was to improve community awareness and knowledge regarding safe delivery practices in health facilities. The methods included a community health assessment using questionnaires, maternal health education sessions, and interactive discussions with pregnant women, families, and community health cadres. The results showed that despite the implementation of health education, some pregnant women still planned home deliveries assisted by non-health personnel due to cultural beliefs, accessibility issues, and financial considerations. The PKMD activities contributed to increased community knowledge; however, continuous education and multisectoral collaboration are required to promote safer delivery practices.

Breast milk (ASI) is the best source of nutrition for newborns because it contains complete, safe, and stable nutrients, thus supporting optimal growth and development of infants. However, some breastfeeding mothers still do not fully understand the sufficiency of breast milk and its benefits for babies. Therefore, health education efforts are needed to improve the knowledge and understanding of breastfeeding mothers regarding breastfeeding. Health education is an educational activity aimed at inviting and encouraging the community to be willing to take actions that can maintain and improve health. This health education activity on the sufficiency of breast milk for breastfeeding mothers was held on January 24, 2026, at the Sungai Durian Community Health Center (UPTD). The method used in this activity was the delivery of material through health counseling accompanied by a measurement of the level of knowledge using pretest and posttest questionnaires. After the presentation of the material, breastfeeding mothers were asked to complete a posttest questionnaire to assess their understanding of the material that had been provided. The measurement results showed a significant difference between the pretest and posttest scores, indicating an increase in knowledge of breastfeeding mothers after being provided with health education. Thus, it can be concluded that health education activities about breast milk sufficiency are effective in increasing the understanding of breastfeeding mothers regarding the importance of providing sufficient breast milk for babies.

Umbilical cord infection remains one of the major causes of morbidity and mortality among newborns, particularly in areas where knowledge and health practices are still limited. Padellegan Village is one of the regions where some mothers continue to practice traditional cord care methods, such as using herbal mixtures or non-sterile materials, which increases the risk of omphalitis. Initial situation analysis indicates that 40–60% of postpartum mothers are not yet familiar with the principles of clean and dry cord care (dry cord care), and access to accurate health information is still limited. Based on this condition, education on umbilical cord care is essential to improve mothers’ and health cadres’ understanding and skills in preventing neonatal infections. This community service activity focuses on providing evidence-based education regarding safe cord care techniques, infection risk factors, and danger signs that need to be recognized. Padellegan Village was selected due to the high need for maternal–neonatal health education and the low level of community knowledge related to cord care. This activity is expected to bring positive changes, such as improved maternal behavior in performing proper cord care, reduced use of unhygienic traditional methods, and strengthened roles of health cadres in monitoring neonatal health. Enhancing appropriate cord care practices can reduce the risk of infection in newborns, thereby contributing to improving the overall health status of the community in Padellegan Village.

The goal of continuous midwifery care is to use the SOAP documentation technique to provide comprehensive care to pregnant women up to birth control according to care standards. From May 2 - July 14, 2025, Mrs.C, G2P1A0, 32 years old received continuous midwifery care from pregnancy until get contraception methods, starting at 34 weeks of gestation. The mother complained of back pain during prenatal check-ups. The labor process went smoothly. With the assistance of a midwife, the baby was born on June 10, 2025. Birth weight: 3000 grams; length: 50 cm; head circumference: 34 cm; chest circumference: 33 cm; received Hb0 vaccine two hours after birth, eye ointment, and vitamin K shortly thereafter. The baby did not experience any problems or complaints during the first visit. Mrs. C received four visits during the postpartum period. The mother did not feel anything during the first visit up to the following visits. She continued to breastfeed exclusively, and her vital signs and fundal height returned to normal. The mother used a three-month injectable contraceptive so as not to interfere with the exclusive breastfeeding program. Mrs.C has received continuous midwifery care during pregnancy and contraceptive use, and her health is normal. It is expected that the midwife will be able to provide continuous midwifery care so that in the event of an emergency, it can be immediately identified and promptly handled.

Umbilical cord infection is one of the leading causes of neonatal mortality in Indonesia. Appropriate umbilical cord care is essential to accelerate separation and prevent infection. In the working area of UPT Puskesmas Alai, variations in cord care practices and delayed separation cases were still found. This study aimed to analyze the effect of umbilical cord care using sterile gauze method on cord separation duration at UPT Puskesmas Alai. The study employed quasi-experimental design with one-group pre-test post-test approach on 32 respondents selected through purposive sampling. Pretest data were obtained from medical records, while posttest data through direct observation. Analysis used Wilcoxon Signed Rank Test (α=0.05). Results showed mean cord separation time in pretest group was 9.2 days (SD=1.08) and posttest group 6.0 days (SD=0.84). Wilcoxon test showed Z=-4.94 with p-value=0.000, indicating significant difference. Umbilical cord care using sterile gauze method effectively accelerates separation time compared to conventional methods. Healthcare workers are recommended to implement this method as standard care.

A high-risk pregnancy is a pregnancy that can affect both the pregnancy, delivery, newborn, and postpartum period. There are several high-risk pregnancies, including pregnant women who are <145cm tall, have low birth weight, are too young, and give birth too closely spaced, or what is known as the 4T. Prevention is carried out by conducting comprehensive supervision, this is a way to reduce MMR and IMR. The Central Java government has developed the One Student One Client (OSOC) program, it is hoped that the implementation of this program can reduce MMR in Central Java. MMR according to WHO in 2023 reached 189/100,000 live births, MMR based on ASEAN reached 235/100,000 live births, MMR according to the Indonesian Ministry of Health reached 205/100,000 live births, MMR in Central Java in 2023 has reached 485/100,000 live births, MMR in Brebes in 2023 54/100,000 live births and at the Bantarkawung Community Health Center MMR in 2023 amounted to 2 cases of maternal death. In this study, researchers used Varney and SOAP to document midwifery care comprehensively, with direct qualitative descriptive approach methods such as observation, interviews, and documentation.

Background : The Maternal Mortality Rate (MMR) worldwide reaches 183,000 per 100,000 live births (WHO, 2024). In Indonesia, there were 4,305 reported cases (Ministry of Health RI, 2024), while Central Java Province recorded 315 cases (Central Java Health Office, 2024). In Brebes Regency, there were 54 maternal deaths in 2024 (Brebes Health Office, 2024), and in the Bumiayu Public Health Center area, 2 maternal deaths were recorded (Bumiayu PHC Data, 2024). Objective : To analyze, implement, and provide comprehensive midwifery care for Mrs. A, 25 years old, with anemia in the Bumiayu Public Health Center area in 2025, using the Varney midwifery management approach and the SOAP method. Research Methods : This study used a qualitative descriptive design in the form of a case study. Results : Midwifery care during pregnancy for Mrs.A with anemia was carried out bassed on the mother’s needs. During labor, newborn care, postpartum period, and family planning services, no complications were found. Conclusion: The comprehensive midwifery care provided to Mrs. A with anemia was carried out in accordance with the Standard Operating Procedures (SOP), with both the mother and baby in good condition.

In Indonesia in 2020, there were 28,158 infant deaths, of which 20,266 (72%) occurred during the neonatal period. Among these neonatal deaths, 27.4% were caused by neonatal asphyxia. In West Kalimantan Province, there were 682 neonatal deaths recorded in 2023. The leading causes of neonatal mortality in 2023 were Low Birth Weight (LBW) and prematurity (32%), followed by asphyxia (24%). Based on the 2023 Sintang Regency health profile, the infant mortality rate was 9.6 per 1,000 live births. This study aimed to determine the relationship between LBW and the incidence of neonatal asphyxia. The research used an analytical observational approach with a cross-sectional design. The study was conducted at Ade M. Djoen Sintang Regional Hospital from January to December 2023 using secondary data. The population consisted of all newborns at Ade M. Djoen Sintang Regional Hospital, totaling 104 infants. A total sampling technique was applied, resulting in a sample size of 104 respondents. Data were analyzed using the Chi-square test. The Chi-square analysis produced a p-value of 0.0241 (p < 0.05), indicating a statistically significant relationship between Low Birth Weight (LBW) and neonatal asphyxia. The Odds Ratio (OR) of 4.021 shows that LBW infants have a 4.021-fold higher risk of experiencing neonatal asphyxia compared to infants with normal birth weight.  

Continuity of Care (CoC) is a midwifery care model that provides continuous care from pregnancy, childbirth, the postpartum period, and newborn care to family planning services. This approach aims to improve the quality of care, enable early detection of complications, and enhance maternal and neonatal health outcomes. This study aimed to describe the implementation of Continuity of Care midwifery services for Mrs. D, aged 25 years, at PMB Siti Nur Azizah, Wonoayu, Sidoarjo, East Java.This study employed a descriptive method with a case study approach. The subject was Mrs. D, a primigravida woman who received midwifery care from the first trimester of pregnancy through the postpartum period, newborn care, and family planning services. Data were collected through interviews, observation, physical examinations, and medical record review.The results showed that throughout pregnancy, both maternal and fetal conditions remained within physiological limits with routine monitoring and adequate health education. Labor occurred spontaneously and normally with the application of respectful maternity care and interventions based on clinical indications. The postpartum period progressed normally with good uterine involution and adequate breast milk production. The newborn demonstrated optimal physiological adaptation and received essential neonatal care. In the family planning phase, Mrs. D chose a three-month injectable contraceptive, which was appropriate for her breastfeeding condition and pregnancy spacing needs.

Background: Maternal mortality according to WHO (2024) is 287,000, in Indonesia (2024) 183/100,000 live births, in Central Java (2024) 3,149 live births, in Brebes (2024) there were 54 cases of maternal mortality. At Bantarkawung Community Health Center (2024), there were no maternal deaths. One of the causes of maternal mortality is postpartum hemorrhage. Postpartum hemorrhage can be caused by anemia in mothers during pregnancy. Objective: It is hoped that the researcher can provide comprehensive midwifery care for Mrs. L in accordance with midwifery service standards, covering pregnancy, childbirth, newborns, neonates, postpartum, and family planning, using the midwifery management approach according to Varney and SOAP. Research method: The method used is qualitative descriptive with a comprehensive case study approach. Findings: During the researcher's assistance with anemia cases, the researcher did not find issues that required further in-depth investigation, but there were some occurrences resulting from anemia, one of which was the mother experiencing retained placenta. From the assistance process conducted by the researcher, the midwifery findings have been applied comprehensively, from pregnancy stages to family planning, in accordance with midwifery service standards.  

This paper applies the Gamma Regression Model to determine the probability of newborns in the Diyala Province developing neonatal jaundice, or hyperbilirubinemia. This disease is prevalent, and it may be severe due to the large amount of unconjugated bilirubin in the blood. The aim of the study was to test the relationship between the levels of bilirubin and a set of independent variables, including the weight of birth, gestational age, and the proportion of red blood cells (PVC). 67 worth of data regarding neonatal cases was collected, and the outcome was that the model fitted well. The findings further indicated that whereas the influence of PVC was significant and positive on the bilirubin level, lower gestational age and less weight at birth had significant negative influence. As the results of the study indicate, the Gamma Regression Model is an effective tool to assess medical data and predict critical scenarios, which assists a clinician with the timely and accurate decision-making.

Sectio caesarean surgery is a surgical procedure that can effectively prevent ma- ternal and newborn deaths when used for reasons of medical indications. Post operative sectio caesarean can pose several risks of complications, one of which is pain and surgical wound infection. Non pharmacological approach aromatherapy as a complementary therapy to reduce postpartum pain. This case study aims to analyze the influence aromatherapy lavender on reducing pain levels in post sectio caesarean mothers by using the case study method pre and post test. The case study was carried out in 25 May 2025 – 07 June 2025. This type of case study is descriptive with the number of subjects used, namely three post partum mothers in the RSUD Batang private sector with pain assessment using a questionnaire Numeric Rating Scale (NRS). The results of the case study showed a change in pain intensity from a scale of 6-7 to a scale of 4-5. This shows an influence aromatherapy lavender on reducing pain levels in postpartum mothers caesarean section Giving innovation aromatherapy can be used as an independent nursing in- tervention so that it can be applied to patients regularly.

The umbilical cord is the main entry point for systemic infection in newborns. Umbilical cord care aims to prevent infection and accelerate the breaking of the umbilical cord. Some postpartum mothers have insufficient knowledge about umbilical cord care so that education is needed. This study aims to determine the effect of education on newborn umbilical cord care on postpartum mothers' knowledge. This research method is a quantitative pre-experimental study using the One Group Pre Test-Post Test without control approach. The study was conducted at RSIA Murni Teguh Rosiva Medan. The population was 101 patients per month and 47 samples were obtained. Sampling was done randomly. Analysis was carried out univariately in a frequency distribution table and bivariately using the Paired Sample T-Test because the data was normally distributed. The results of the study showed that before being given education (pretest) the majority of postpartum mothers had poor knowledge (53.2%) with an average value of 5.09 ± 1.501, after being given education (posttest), the majority of postpartum mothers had good knowledge (70.2%) with an average value of 8.19 ± 1.096. Providing education on newborn umbilical cord care had a significant effect on increasing the knowledge of postpartum mothers at RSIA Murni Teguh Rosiva Medan, obtained p-value = 0.000 <0.05. There was a difference in the knowledge of postpartum mothers before and after being given education on newborn umbilical cord care (pretest-posttest). The conclusion of the study was that mothers' knowledge of umbilical cord care increased after being given education. It is recommended for further researchers to conduct further research using other research variables such as attitudes, motivations, perceptions, and others, to complement the existing research results.

Umbilical cord care is an important part of newborn care because the umbilical cord that has not fallen off has the potential to become an entry point for germs if not cared for hygienically. In the community, traditional umbilical cord care practices are still widely practiced and often do not comply with medical standards. This study aims to determine the effect of umbilical cord care education on cleanliness and duration of umbilical cord detachment in newborns in the Bongo 2 Community Health Center, Boalemo Regency. This study used a pre-experimental design with a one-group pretest-posttest approach. The study sample consisted of 24 newborns selected using a total sampling technique. The intervention in the form of umbilical cord care education was given to the parents of the babies, then measurements were taken of umbilical cord cleanliness and duration of umbilical cord detachment before and after education. Data analysis was performed using a paired t-test or Wilcoxon signed-rank test with a significance level of p < 0.05. The results showed an increase in umbilical cord cleanliness after education, with a p value = 0.001. In addition, the average duration of umbilical cord detachment decreased significantly after education, with a p value = 0.000. This study concludes that umbilical cord care education has a significant effect on improving hygiene and optimizing the duration of umbilical cord removal in newborns.

Complete basic immunization for infants is an important effort in preventing infectious diseases and improving public health. However, certain regions still have subpar vaccination rates, which may be due to parents' ignorance and attitudes. Children who do not receive all recommended vaccinations are more vulnerable to illness and, worse, may die from it. This study was conducted at the Jikohay Community Health Center in the West Obi District to examine the impact IEC on mothers' attitudes and knowledge on the provision of full basic immunizations for newborns. Maternal and child health books (KIA) and a questionnaire approach were used in this qualitative study. The purpose of this study is to ascertain how IEC affects mothers' knowledge and attitudes on giving their babies the recommended basic vaccinations at the Jikohay Health Center in the West Obi District. There were 60 individuals in the population and 40 responders in the sample. Purposive sampling was used for the sample process. The Wilcoxon test was utilized for data analysis. According to the study's findings, 20 respondents had good attitudes, 20 had sufficient attitudes, and 29 had good knowledge, 10 had sufficient knowledge, and 1 had insufficient knowledge after receiving counseling on parental attitudes and knowledge in providing full basic immunizations to infants. At the Jikohay Health Center in the West Obi District, the results of the statistical test with a p-value of 0.000 indicated that IEC had an impact on mothers' attitudes and knowledge toward giving their infants all of the recommended basic vaccinations.