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Neonatal sepsis is a major factor contributing to morbidity and mortality in newborns. C-Reactive Protein (CRP) and leukocytes are laboratory tests used as indicators of inflammation. This study aims to determine the relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients. The research method used was an observational analytic with a cross-sectional approach. Neonatal sepsis at PKU Muhammadiyah Yogyakarta in the period 2021-2026 consisted of 30 samples using a total sampling technique. The distribution of respondents was dominated by male gender compared to female gender, who had a low birth weight <2,500 grams. Based on the study, normal CRP levels were found in 21 respondents, which was caused by a delay in increasing CRP levels. Leukocytes had high levels in 18 respondents. Leukocytes are an initial phase of examination in detecting inflammation that does not require a long time, have several different morphological types in detecting inflammation in the body. This study shows that the most dominant increase in leukocyte levels is found in eosinophils and neutrophils. Based on medical record data at PKU Muhammadiyah Hospital Yogyakarta, analysis using the Spearman correlation test yielded a correlation coefficient of 0.261 with a significance value of 0.164 (p > 0.05). The results showed no significant relationship between the studied variables, with a positive direction and weak correlation strength. The conclusion of this study is that there is no significant relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients.

Neonatal sepsis is a major factor contributing to morbidity and mortality in newborns. C-Reactive Protein (CRP) and leukocytes are laboratory tests used as indicators of inflammation. This study aims to determine the relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients. The research method used was an observational analytic with a cross-sectional approach. Neonatal sepsis at PKU Muhammadiyah Yogyakarta in the period 2021-2026 consisted of 30 samples using a total sampling technique. The distribution of respondents was dominated by male gender compared to female gender, who had a low birth weight <2,500 grams. Based on the study, normal CRP levels were found in 21 respondents, which was caused by a delay in increasing CRP levels. Leukocytes had high levels in 18 respondents. Leukocytes are an initial phase of examination in detecting inflammation that does not require a long time, have several different morphological types in detecting inflammation in the body. This study shows that the most dominant increase in leukocyte levels is found in eosinophils and neutrophils. Based on medical record data at PKU Muhammadiyah Hospital Yogyakarta, analysis using the Spearman correlation test yielded a correlation coefficient of 0.261 with a significance value of 0.164 (p > 0.05). The results showed no significant relationship between the studied variables, with a positive direction and weak correlation strength. The conclusion of this study is that there is no significant relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients.

This study is based on problems that often occur in patients at NU Mangir Hospital with the aim of this study as an effort to detect several possibilities that occur so that it becomes a solution to minimize existing symptoms. This study uses quantitative research with the type of data collection taken based on random sampling techniques from existing patients and then analyzed using statistics with the help of SPSS version 20.00. Infection in patients with Water Seal Drainage (WSD) is a serious problem that increases morbidity and mortality. This study aims to identify demographic and clinical factors that influence the incidence of infection in WSD patients at NU Mangir Hospital, Banyuwangi. The method used is a cross-sectional approach with purposive sampling of 24 respondents. The results showed that systemic infections occurred most often (45.8%), and age factors, length of WSD installation, leukocyte levels, and comorbidities were significantly related to the incidence of infection. Improvement in the quality of care is needed to reduce the risk of infection.

Bronchopneumonia is a type of pneumonia that affects the bronchi and alveoli, usually starting in the terminal bronchioles. The terminal bronchioles become blocked with mucopurulent exudate forming patches of consolidation in adjacent lobules. 95% of pneumonia cases in children occur in developing countries. According to WHO estimates, the infant mortality rate due to pneumonia in developing countries is 40 out of 1000 live births or around 15-20% per year. A 5-year-old boy was brought to the Emergency Room of Cut Meutia Hospital with complaints of shortness of breath since 3 days before admission accompanied by a cough with phlegm and fever. The results of a physical examination of the thorax found nasal flaring breathing, chest wall retraction, and rhonchi (+/+). Based on laboratory tests, there was an increase in leukocytes, then a chest X-ray showed an impression of infiltration in the perihilar and paracardial. Based on history, physical examination, and supporting examinations, the patient was diagnosed with Bronchopneumonia. Non-medical management is done through bed rest, balanced nutrition, and adequate fluid balance. Then the patient's medical management is in the form of Cefotaxime injection 500 mg/12 hours, symptomatic management and supportive management for the bronchopneumonia..

In previous research, mango rind extract has been studied as an antioxidant, antihypertensive, and antidiabetic, because it contains flavonoids and 17% mangiferin compounds. In this research, the effect of arumanis mango rind extract gel (Mangifera indica L.) as an anti-inflammatory was tested in male white mice induced by carrageenan using the granuloma pouch method. This experimental study used experimental white male mice which were grouped into 5 groups: the control group, the group with 2% mango rinf extract, the group with 4% mango rind extract, the group with 8% mango rind extract, and the comparison group. The parameters that were analyzed were exudate volume, total leukocytes, and type of leukocytes on days 3, 5, 7. The results showed that mango arumanis (Mangifera indica L.) rind extract had anti-inflammatory effectiveness topically as indicated by a decrease in the average exudate volume, total leukocytes, and leukocyte cell types (segmented neutrophil cells and lymphocyte cells) in each concentration group of mango rind extract, based on two-way ANOVA test and Duncan's test showed significant differences with respect to concentration and time (p<0.05). It can be concluded that all gel concentrations of arumanis mango rind extract (Mangifera indica L.) 2%, 4%, and 8% have anti-inflammatory effects.

Sleep quality is a state lived by an individual to produce freshness and fitness after waking up. If a person's sleep quality is poor it will cause a decrease in the body's immune system and Hb levels which causes the individual to feel easily tired, sleepy and susceptible to disease. Adolescents are identified as a population at high risk of experiencing sleep problems which disrupt sleep quality. Accumulated work and lifestyle are one of the factors causing poor sleep patterns in adolescents which makes it easier for them to experience sleep disturbances. Adolescents with high risk certainly need adequate knowledge regarding the importance of maintaining quality sleep related to the body's immune system and Hb levels. Increased knowledge and examination can be carried out by laboratory personnel with health counseling and laboratory tests. The purpose of this community service is to increase the knowledge of adolescents to maintain good quality sleep so that Hb levels and body immunity are maintained. This community service implementation method consists of three stages, namely the preparation, implementation, and evaluation stages. At the implementation stage, an examination of Hb levels and counting the number of types of leukocytes was carried out as well as education related to the effect of sleep quality on Hb levels and the body's immune system. As a result of community service, adolescents have obtained health status through laboratory tests and good knowledge about the effect of sleep quality on Hb levels and body immunity.