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Radiological examination is a diagnostic supporting procedure aimed at visualizing the internal structures of the human body to assist in establishing a diagnosis. One of the examinations performed is the Acromioclavicular Joint examination, which is used to identify abnormalities of the acromioclavicular joint. This study aims to compare the imaging results of the Acromioclavicular Joint using the anteroposterior (AP) projection with a 3 kg weight and the AP projection without a weight. The study was conducted at the Radiology Laboratory of STIKES Boneo Nusantara, Diploma III Radiology Study Program, using a conventional radiography unit and a quantitative descriptive method with a case study approach. Data were collected through observation and questionnaires. The results showed that the examination using a 3 kg weight produced clearer Acromioclavicular Joint images than the examination performed without a weight. The difference was reflected in the improved visualization of the anatomical structures, thereby facilitating a more accurate assessment of the joint. This study concludes that the use of a 3 kg weight in the AP projection provides superior imaging results by enhancing the visualization of the anatomy of the shoulder joint, thereby potentially improving the accuracy of the radiological evaluation of the Acromioclavicular Joint.

Radiological examination is a diagnostic supporting procedure aimed at visualizing the internal structures of the human body to assist in establishing a diagnosis. One of the examinations performed is the Acromioclavicular Joint examination, which is used to identify abnormalities of the acromioclavicular joint. This study aims to compare the imaging results of the Acromioclavicular Joint using the anteroposterior (AP) projection with a 3 kg weight and the AP projection without a weight. The study was conducted at the Radiology Laboratory of STIKES Boneo Nusantara, Diploma III Radiology Study Program, using a conventional radiography unit and a quantitative descriptive method with a case study approach. Data were collected through observation and questionnaires. The results showed that the examination using a 3 kg weight produced clearer Acromioclavicular Joint images than the examination performed without a weight. The difference was reflected in the improved visualization of the anatomical structures, thereby facilitating a more accurate assessment of the joint. This study concludes that the use of a 3 kg weight in the AP projection provides superior imaging results by enhancing the visualization of the anatomy of the shoulder joint, thereby potentially improving the accuracy of the radiological evaluation of the Acromioclavicular Joint.

Anemia during pregnancy remains a common health problem and may lead to adverse outcomes for both mother and fetus. Hemoglobin and erythrocyte indices examination are important to identify anemia and describe erythrocyte morphology in pregnant women. This study aimed to describe hemoglobin levels and erythrocyte indices among anemic pregnant women at Sentosa Maternity Hospital. This research used a descriptive design with secondary data obtained from hematological examination results of pregnant women who underwent laboratory testing at Sentosa Maternity Hospital from January to December 2023. Data were analyzed descriptively and presented in frequency distribution tables. The results showed that out of 58 pregnant women undergoing hematological examination, 28 women (48%) were anemic with a mean hemoglobin level of 10.2 g/dL, while 30 women (52%) had normal hemoglobin levels with a mean of 12.8 g/dL. Based on erythrocyte indices, most anemic pregnant women had microcytic hypochromic anemia, accounting for 19 women (67%) with mean MCV of 72.3 fL, MCH of 29.8 pg, and MCHC of 33.9 g/dL, whereas 9 women (33%) had normocytic normochromic anemia with mean MCV of 83.4 fL, MCH of 29.6 pg, and MCHC of 33.4 g/dL. It can be concluded that nearly half of the examined pregnant women experienced anemia, with microcytic hypochromic anemia being the most dominant type.

Thalassemia is an inherited hemolytic anemia caused by genetic abnormalities in chromosomes 11 and 16 that impair globin chain production, leading to insufficient hemoglobin and red blood cells. This study aims to describe nursing care for An. W with thalassemia at the Anggrek 2 Ward of RSUD dr. Soeselo, Tegal Regency. The method used was a descriptive approach through anamnesis, documentation, observation, and literature review. Nursing care was carried out over two days (January 13–14, 2026). Physical examination results on January 12, 2026 showed a pale face, anemic conjunctiva, weakness, CRT >3 seconds, decreased skin turgor, weak peripheral pulse, cold extremities, and laboratory hemoglobin of 5.9 g/dL, with vital signs of pulse 111x/minute, temperature 36.7°C, and respiration 22x/minute. Two nursing diagnoses were established: ineffective peripheral perfusion related to decreased hemoglobin concentration (D.0009), and activity intolerance related to weakness (D.0056). Nursing interventions included circulatory care (I.02079) and energy management (I.05178). Nursing implementation was carried out according to plan. Evaluation on January 14, 2026 showed that both nursing diagnoses were resolved; the patient's hemoglobin improved to 10.7 g/dL after two blood transfusions, and the patient was declared fit for discharge. It is recommended that hospitals establish support groups for thalassemia patients to provide adequate emotional and social support.

Agentic artificial intelligence (AI) systems capable of autonomous goal-directed behavior, multi-step planning, tool use, multi-agent coordination, and iterative self-correction represent a transition from passive clinical AI tools toward systems that can participate in complex healthcare workflows. However, empirical evidence remains fragmented across clinical decision support, patient monitoring, and administrative applications, and no systematic synthesis has evaluated which agentic principles have been technically demonstrated and which have accumulated sufficient evidence to support responsible clinical deployment. We conducted a PRISMA-informed systematic review of peer-reviewed empirical studies published between January 2025 and April 2026. Searches across five bibliographic databases and Google Scholar, supplemented by citation tracking, identified 443 unique records for screening, of which 25 met the predefined PICOS and quality appraisal criteria. Evidence was synthesized using an evidence-informed seven-principle framework derived from the integration of agentic AI, clinical AI, and healthcare governance literature. This framework provides a structured lens for examining how agentic principles are evaluated individually and in combination, enabling a deployment-readiness perspective that extends beyond capability-focused assessments alone. The evidence base was concentrated on technical capability principles, whereas human oversight, safety, compliance, and equity-related evaluation received comparatively limited attention. Most studies remained at the laboratory, benchmark, or proof-of-concept stage, and none reported demographic-stratified performance outcomes. Overall, the findings suggest a structural asymmetry in agentic healthcare AI: empirical research is advancing agentic capabilities more rapidly than it is generating evidence for the oversight, safety, equity, and governance mechanisms required for responsible clinical translation.

Non-Communicable Diseases (NCDs) such as Diabetes Mellitus and Gout pose a serious threat to the health of the elderly due to their often asymptomatic nature. Cost barriers hinder the elderly community from accessing laboratory services. This community service activity aims to improve health standards and early detection of NCDs through monitoring blood glucose and uric acid levels in the Generasi Kaleb community of the JKI Injil Kerajaan Church, Semarang. The Participatory Health Screening and Education method used includes health education, screening using the Point of Care Testing (POCT) tool, and personal consultation on the results. The service subjects were 50 elderly respondents. The examination results showed a prevalence of abnormal random blood glucose (GDS) of 8%, 32%, had high uric acid levels with a maximum value of 10.3 mg/dL. This activity successfully transformed the elderly's awareness from subjective perception to awareness based on objective data, and encouraged community independence in managing a healthy lifestyle to prevent further NCD complications. .

Construction project control requires careful planning to avoid delays and cost overruns. This study aims to evaluate the performance of the CBT Laboratory Building construction project at the Faculty of Medicine, Wahid Hasyim University, Semarang, in terms of cost and time using the Earned Value Analysis (EVA) method, and to analyze acceleration alternatives using the crashing method. The method used is a quantitative approach with a case study, based on project data such as the Budget Plan (RAB), S-curve, and work progress reports. The analysis was carried out using the Earned Value Analysis (EVA) method to assess project performance in terms of cost and time through indicators such as CV, SV, CPI, and SPI. Furthermore, an acceleration analysis was conducted using the crashing method to determine the optimal alternative for overcoming project delays by considering time and cost efficiency. The results of the Earned Value Analysis indicate that the project experienced delays and cost overruns, as shown by SPI < 1 and CPI < 1. The estimated project completion time increased to 227 days, longer than the initial plan of 217 days, while the estimated final cost reached RP 5,451,241,064.85, exceeding the initial budget. Acceleration efforts using the crashing method show that adding adding labor is more efficient than working hours (overtime), resulting in a project duration of 212 days with lower costs of RP 5,658,221,364.08. Thus, the Earned Value Analysis method is effective for evaluating project performance, while crashing can be a solution for acceleration by considering time and cost efficiency.

The quality of rice that is suitable for consumption, one of which is determined by the absence of associated components when the rice is in storage. Rice storage is carried out by means of long shelf life and good rice quality. Damage to rice due to pest attacks causes a decrease in quality and quantity. Environmentally friendly efforts are needed to control the rice weevil Sitophilus oryzae using vegetable materials. This study sought to ascertain the death rate of rice weevils treated with lemongrass stem (Cymbopogon citratus), bay leaves (Syzygium polyanthum), and pandan leaves (Pandanus amaryllifolius). The study employed a fully randomized design with three treatments in the form of simplicia plant components. There were 21 study units because each treatment included seven repetitions. Each treatment used 20 rice weevil imago breeding results which were infested in a jar containing 200 g of rice for 4 weeks in the laboratory. The use of pandan leaf, bay leaf, and lemongrass simplicia at 7 days after treatment showed the proportion of rice weevil mortality was 59,29%, 39,29%, and 50,00%, respectively. As for the observations of 14 day after treatments, 21 day after treatments, and 28 day after treatments showed that the mortality rate of all rice beetles was above 50%. Regarding the percentage of rice powder, hollow rice, and rice weight loss, the findings of observations on rice weevil mortality did not reveal any significant variations across all treatments.

Background: Acne vulgaris is one of the most common skin problems and is closely associated with the activity of Propionibacterium acnes. Long-term use of antibiotics may lead to bacterial resistance; therefore, alternative antibacterial agents derived from natural products are needed. White rice (Oryza sativa L.) is known to contain bioactive compounds such as flavonoids, alkaloids, terpenoids, tannins, and saponins, which potentially exhibit antibacterial activity. Objective: This study aimed to evaluate the antibacterial activity of ethanol extract of white rice against the growth of Propionibacterium acnes. Methods: This research was conducted as a laboratory experimental study using a post-test only control group design. The ethanol extract of white rice was prepared by maceration using 70% ethanol. Antibacterial activity was evaluated using the disc diffusion method with extract concentrations of 100%, 50%, 25%, 12.5%, and 6.25%. Clindamycin was used as a positive control, while sterile distilled water served as a negative control. The parameter observed was the diameter of the inhibition zone. Result: The results of phytochemical screening showed that the ethanol extract of white rice (Oryza sativa L.) contains flavonoids, alkaloids, and terpenoids. Antibacterial activity test showed that the ethanol extract of white rice at concentrations of 100%, 50%, and 25% was able to inhibit the growth of Propionibacterium acnes by forming an inhibition zone, while at concentrations of 12.5% and 6.25% no inhibition zone was formed. The highest inhibition zone diameter was found at a concentration of 100%. The ethanol extract of white rice at concentrations of 100% (7.65 mm), 50% (6.77 mm), and 25% (6.15 mm) was able to inhibit the growth of Propionibacterium acnes, and was classified as having moderate inhibition. In contrast, at concentrations of 12.5% and 6.25%, the ethanol extract of white rice did not show any inhibitory activity detected in vitro using the disc diffusion method. The results of statistical analysis showed a p value <0.001, which means there was a significant difference in the diameter of the inhibition zone between the treatment groups. Conclusion: In conclusion, the ethanol extract of white rice exhibits antibacterial activity against Propionibacterium acnes in a concentration-dependent manner; however, its inhibitory effect remains lower than that of clindamycin.

Rheumatoid arthritis (RA) is a daily disease seen in rheumatology clinics. It predominantly involves the appendicular skeleton. The axial skeleton is mostly spared except for the cervical spine where instability can occur and can be carefully assessed with cervical spine radiographs in flexion and extension. Radiographs may show erosion at the C1-C2 level with destruction of the transverse ligament that can result in atlantoaxial subluxation. Diagnosis is based on clinical, laboratory, and radiographic findings. Conventional radiography has been the mainstay for diagnosis of joint damage and subsequent follow-up. Radiography can provide only indirect information on synovial inflammation, however, and the technique is insensitive to early bone damage. Hand radiographs are frequently ordered as the first imaging modality in the assessment of patients presenting with peripheral arthritis. They can provide invaluable information about the bones, joints, mineralization, soft tissues and the distribution of abnormalities. Given the wide spectrum of rheumatic diseases, it might be challenging to make the diagnosis solely based on the clinical findings and imaging plays an important role in narrowing the differential diagnosis. Having the knowledge of the common radiographic manifestations of inflammatory arthritis is of paramount importance for clinicians and radiologists to diagnose the underlying disease in early stages of disease in order to start treatment. The purpose of the article is to review the key radiographic findings of common rheumatic diseases in the hands.

Typhoid fever is a febrile illness that commonly occurs in urban areas with poor sanitation. It is usually caused by the consumption of untreated water and contaminated food. Because the S. typhi bacterium can survive in water for days, contamination of surface water—such as wastewater, freshwater, and groundwater—serves as the primary cause of typhoid fever. The patient presented to the Emergency Department of Cut Meutia General Hospital with complaints of high fever for approximately 4 days prior to admission, which had worsened over the past 2 days. The fever fluctuated and was accompanied by chills. It worsened at night and was not influenced by weather or temperature. These symptoms were accompanied by vomiting every time the patient tried to eat, nausea, abdominal pain, headache, and weakness. The patient reported vomiting the contents of their meal every time they ate, leading to a loss of appetite. These symptoms began when the patient first developed a fever. The patient also experienced abdominal pain. Spontaneous bleeding was denied. On physical examination, the patient appeared weak but was alert and oriented. On neck examination, palpable enlargement of the thyroid glands was found on the right and left sides of the neck, measuring 2x2 cm, mobile, and soft. On abdominal examination, increased bowel sounds were noted. Vital signs were normal except for the patient’s febrile temperature. Laboratory tests revealed a Tubex blood test result of scale 4 and a positive dengue IgG serology result.

SR12 Herbal Cosmetics is a company engaged in the field of herbal and skin care. Founded in 2015 byToni Firmansyah, S. Farm., Apt. and Asrianty Salam, Farm. This company has a vision to provide benefits to many people through the herbal and skin care products they produce. SR12 Herbal Cosmetics products are formulated based on research from certified scientists, and have been tested at the Sucofindo Laboratory, are free of mercury and hydroquinone, and have been registered with the Indonesian Food and Drug Supervisory Agency (BPOM RI). SR12 Herbal Cosmetics has several factories in West Java Province and has an extensive distribution network with hundreds of distributors and tens of thousands of partners throughout Indonesia. The goal to be achieved is to produce a management information system model including a management information system for PT SR12 Herbal Cosmetics. The research object chosen is a company in the field of cosmetics and skin care which has its head office in Gunung Sindur, West Java. This selection aims to form a management information system design model that is able to produce relevant and timely information for planning, controlling, decision making and evaluating the performance of activities. For the Web-Based Instagram Content Management Information System Design project to Support SR12 Herbal Cosmetics' Brand Awareness, I used Agile (Scrum) due to the dynamic nature of digital marketing and potential changes to the Instagram API or business needs. This allowed SR12 to get core functionality faster and provide iterative feedback, ensuring the system built was truly relevant to their brand awareness needs.

This study aims to determine the implementation of quality standard-based health laboratory management at UPTD LABKESDA Kota Serang. The focus of the study includes planning, implementation, supervision, and evaluation of quality standards in health laboratory services. This research employed a qualitative method with an observational study approach. Data collection techniques were conducted through observation, interviews, and documentation involving parties engaged in laboratory management. Data analysis was carried out through data reduction, data presentation, and conclusion drawing. The results of the study indicate that health laboratory management at UPTD LABKESDA Kota Serang has implemented quality standards in various aspects of service, including administrative management, quality control of examinations, management of facilities and infrastructure, and improvement of laboratory personnel competencies. However, several obstacles were still identified, such as limited human resources, supporting facilities that are not yet optimal, and the need for periodic supervision and evaluation improvements. The implementation of quality standard-based management is considered capable of improving the effectiveness of laboratory services and maintaining public trust in health examination results. Based on the findings, it can be concluded that the implementation of quality standard-based health laboratory management at UPTD LABKESDA Kota Serang has been carried out fairly w, although further improvements and developments are still needed to optimize the quality of laboratory services.

Blood is a major component of the homeostatic system that plays an essential role in maintaining the physiological balance of the body. Several blood chemistry parameters, including blood glucose, cholesterol, and blood pH levels, can be used to assess an individual's health condition. Blood glucose is derived from carbohydrate metabolism and serves as the body's primary energy source. Cholesterol is a lipid compound involved in cell membrane formation and hormone synthesis and consists of Low-Density Lipoprotein (LDL) and High-Density Lipoprotein (HDL). Blood pH measurement is used to determine the degree of acidity or alkalinity of the blood, reflecting the body's acid-base balance. This study aims to interpret the results of blood chemical analyses and understand the principles and methods used to determine blood glucose, cholesterol, and pH levels. The research employed a laboratory experimental method by measuring these parameters using blood chemistry testing equipment on blood samples. The results showed that fasting blood glucose was 97 mg/dL, indicating a normal glucose level. In contrast, non-fasting blood glucose was 61 mg/dL, which was below the normal range and indicated hypoglycemia. Blood cholesterol was measured at 139 mg/dL, which remained within the normal range. The blood pH value was 6, indicating a condition of acidosis. These findings highlight the importance of blood chemistry examinations as indicators for evaluating metabolic conditions and overall health status.

Drowning is one of the leading causes of accidental death worldwide and remains a major challenge in forensic investigations due to the complexity of determining the exact cause and mechanism of death. This study aimed to analyze forensic investigation methods used to determine the cause of death in drowning cases. The research employed a qualitative descriptive literature review approach by analyzing scientific articles, forensic journals, and medical references related to drowning investigations. Data were collected through literature searches from Google Scholar, PubMed, and Portal Garuda using keywords related to forensic drowning investigations. The findings indicate that forensic investigation in drowning cases requires a comprehensive approach involving external examination, autopsy, laboratory examination, histopathology, diatom analysis, toxicology, and crime scene investigation. Typical forensic findings include foam cone, washerwoman’s hands, cutis anserina, emphysema aquosum, and the presence of foreign materials in the respiratory and digestive tracts. Diatom examination and histopathological analysis also play important roles in strengthening the diagnosis of drowning. The study concludes that an integrated forensic investigation based on scientific evidence is essential to accurately determine the cause and manner of death in drowning cases and to support medicolegal processes in Indonesia.

Nile tilapia (Oreochromis niloticus) culture requires an efficient and low-cost feeding strategy that can support fry growth and survival. This study aimed to analyze the effects of three types of natural feed, namely silk worms, earthworms, and snails, on absolute length growth, absolute weight growth, and survival of Nile tilapia fry. The study was conducted at the Aquaculture Laboratory, Faculty of Science and Computer Science, Universitas Muhammadiyah Gorontalo, from January 31 to March 2, 2026. An experimental method was applied using a Completely Randomized Design consisting of three treatments and three replications. A total of 45 Nile tilapia fry were reared in 9 plastic containers filled with 10 L of water, with 5 fish in each container. Growth and survival data were analyzed using ANOVA at the 5% significance level, while water quality was analyzed descriptively. The results showed that the type of natural feed had no significant effect on absolute length growth, absolute weight growth, and survival. Descriptively, silk worms produced the highest length and weight growth, with values of 2.99 cm and 6.37 g, respectively. Snails produced the highest survival rate of 86.66%. Water quality remained stable, with temperature ranging from 26.3 to 26.8°C, pH from 7.6 to 7.9, and dissolved oxygen from 5.2 to 5.6 mg/L. These findings indicate that silk worms are potential natural feed for improving growth, while snails support the survival of Nile tilapia fry.

This study analyzes the regulatory gaps in digital forensics regarding the handling of natural resource crimes and the state’s constitutional responsibilities following the enactment of Law No. 1 of 2024. Modern natural resource crimes, such as illegal logging and illegal mining, have evolved to leverage digital technology, leaving complex electronic traces in the form of GPS data and digital documents. However, Indonesia still faces procedural gaps in the Criminal Procedure Code (KUHAP), unclear technical standards (SNI 27037:2014 is voluntary in nature), and conflicts between the Information and Electronic Transactions Law (UU ITE) and sectoral NRE laws. This normative legal study employs legislative, conceptual, and case-based approaches. The research findings indicate that the absence of digital forensic authentication standards has fatal implications, as evidenced by the Sidoarjo District Court Decision No. 488/Pid.B/2024/PN Sda, which rejected electronic evidence. This situation constitutes state negligence (staatsverzuim) that violates Article 1(3) and Article 33(3) of the 1945 Constitution of the Republic of Indonesia. The study recommends the development of standard digital forensic procedures, the acceleration of ISO/IEC 17025 laboratory accreditation, and the harmonization of sectoral regulations

Typhoid fever remains a significant diagnostic challenge, particularly regarding the interpretation of Widal test results which are often affected by antibody persistence. This study aims to analyze the variations in Widal antibody titers among students at Universitas Muhammadiyah Purwokerto, focusing on the time interval since their last confirmed infection. Using a cross-sectional design, serum samples from 24 students were analyzed through the semi-quantitative slide agglutination technique to detect Salmonella typhi O and H agglutinins. The findings indicated that anti-Salmonella O titers could persist up to 1:320 in individuals with an infection history of more than one year. In contrast, anti-Salmonella H was only identified in more recent infections (less than a year) with a lower titer of 1:80, and was undetectable in samples from infections exceeding one year. These results demonstrate that O antigens remain detectable in the blood significantly longer than H antigens. This study suggests that the duration since the last infection is a critical factor in the screening and validation of Widal test results. Accurate identification of these titer variations is essential for clinical laboratory technologists to provide more precise diagnostic data and support effective clinical management.

Typhoid fever remains a significant diagnostic challenge, particularly regarding the interpretation of Widal test results which are often affected by antibody persistence. This study aims to analyze the variations in Widal antibody titers among students at Universitas Muhammadiyah Purwokerto, focusing on the time interval since their last confirmed infection. Using a cross-sectional design, serum samples from 24 students were analyzed through the semi-quantitative slide agglutination technique to detect Salmonella typhi O and H agglutinins. The findings indicated that anti-Salmonella O titers could persist up to 1:320 in individuals with an infection history of more than one year. In contrast, anti-Salmonella H was only identified in more recent infections (less than a year) with a lower titer of 1:80, and was undetectable in samples from infections exceeding one year. These results demonstrate that O antigens remain detectable in the blood significantly longer than H antigens. This study suggests that the duration since the last infection is a critical factor in the screening and validation of Widal test results. Accurate identification of these titer variations is essential for clinical laboratory technologists to provide more precise diagnostic data and support effective clinical management.

This research aims to compare coal quality based on proximate analysis in two seams with varying depths in Pit North and evaluate the relationship between depth and coal quality parameters. The research method includes taking representative samples at each seam and proximate analysis laboratory testing including inherent moisture, ash content, volatile matter, and fixed carbon. The results showed that seam 1 at an average depth of 59.8 m had an inherent moisture value of 13.51%, ash 4.68%, volatile matter 39.93%, and fixed carbon 41.88%, while seam 2 at an average depth of 82.1 m had inherent moisture 13.42%, ash 4.59%, volatile matter 40.15%, and fixed carbon. 41.84%. Correlation analysis shows that the relationship between depth and coal quality parameters is relatively weak with correlation coefficient values ​​ranging from −0.36 to 0.25 and a low coefficient of determination, so that variations in depth do not have a significant influence on coal quality at the research location.