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Nurhalmiyanti Nurhalmiyanti; Aloysia Ispriantari

Jurnal Ilmu Kesehatan dan Gizi 2026 Pusat Riset dan Inovasi Nasional

Type 2 diabetes mellitus is a chronic condition marked by elevated blood glucose levels resulting from insulin resistance and decreased insulin secretion. Effective glycemic control is crucial to prevent complications, and HbA1c is commonly utilized as an indicator of long-term blood glucose levels. This study aimed to examine the relationship between HbA1c levels and blood glucose levels among patients with type 2 diabetes mellitus at Tilamuta Community Health Center, Boalemo Regency, Gorontalo Province. This study employed an analytical cross-sectional design using a total sampling method, involving 557 patients. Data were collected from laboratory records and analyzed through descriptive statistics, the Shapiro-Wilk test for normality, Spearman correlation, and chi-square test. The findings indicated that the average HbA1c level was 7.39%, while the mean blood glucose level was 205.85 mg/dL. A significant and very strong positive correlation was found between HbA1c and blood glucose levels (p=0.000; r=0.862). Furthermore, medication adherence showed a significant association with HbA1c status (p=0.000). These results underscore the role of HbA1c as a dependable marker for assessing glycemic control and highlight the importance of medication adherence in optimizing the management of type 2 diaType 2 diabetes mellitus is a chronic condition marked by elevated blood glucose levels resulting from insulin resistance and decreased insulin secretion. Effective glycemic control is crucial to prevent complications, and HbA1c is commonly utilized as an indicator of long-term blood glucose levels. This study aimed to examine the relationship between HbA1c levels and blood glucose levels among patients with type 2 diabetes mellitus at Tilamuta Community Health Center, Boalemo Regency, Gorontalo Province. This study employed an analytical cross-sectional design using a total sampling method, involving 557 patients. Data were collected from laboratory records and analyzed through descriptive statistics, the Shapiro-Wilk test for normality, Spearman correlation, and chi-square test. The findings indicated that the average HbA1c level was 7.39%, while the mean blood glucose level was 205.85 mg/dL. A significant and very strong positive correlation was found between HbA1c and blood glucose levels (p=0.000; r=0.862). Furthermore, medication adherence showed a significant association with HbA1c status (p=0.000). These results underscore the role of HbA1c as a dependable marker for assessing glycemic control and highlight the importance of medication adherence in optimizing the management of type 2 diabetes mellitus.betes mellitus.  

Rahma Fitri Choirunnisa; Lukman Hakim; Kusno Ferianto; Mei Widiawati

Jurnal Ilmu Keperawatan dan Kebidanan 2026 Asosiasi Riset Ilmu Kesehatan Indonesia

Type 2 diabetes is a persistent medical condition with an increasing incidence that requires long-term treatment. One of the decisive factors in blood glucose control Patient self-awareness is a key variable examined in this study. The research was conducted to assess the relationship between self-awareness and blood glucose levels among individuals with type 2 diabetes in the Tuban Community Health Center area. A correlational analytic study with a cross-sectional design was utilized. The study involved a population of 135 patients, with a sample of 101 respondents selected using simple random sampling.Research data collection was conducted using a self-awareness questionnaire and a blood glucose observation sheet. Data analysis was performed using a chi-square test with a significance level of 0.05. The results of the analysis showed a p-value of 0.002 (p < 0.05), indicating a significant association between self-awareness and blood glucose levels. Based on these results, the study findings generally indicate that greater self-awareness typically allows for more optimal control of blood glucose levels.  

Alexander Halim Santoso; Wijaya, Bryan Anna; Setiawan, Fiona Valencia

Jurnal Riset Rumpun Ilmu Kesehatan 2026 Pusat riset dan Inovasi Nasional

Sindrom metabolik merupakan isu kesehatan yang semakin menonjol di Indonesia, dengan prevalensi mencapai 21,66% dan angka lebih tinggi pada populasi urban. Literasi gizi, sebagai kapasitas individu untuk memahami dan menerapkan informasi nutrisi, dipandang berperan penting dalam mengarahkan perilaku makan serta memengaruhi status metabolik. Namun, pada komunitas adat seperti masyarakat Badui, struktur sosial-budaya dan pola hidup tradisional dapat menciptakan dinamika yang berbeda dibandingkan populasi umum. Penelitian ini bertujuan menganalisis hubungan antara tingkat literasi gizi dan parameter kesehatan metabolik pada masyarakat Badui Luar. Studi observasional dengan desain potong lintang ini melibatkan 41 responden dewasa. Literasi gizi diukur menggunakan kuesioner terstandar, sedangkan parameter metabolik meliputi lingkar perut, tekanan darah, kadar glukosa darah puasa, trigliserida, dan HDL yang diperiksa menggunakan metode klinis sederhana. Analisis korelasi Pearson digunakan untuk menilai hubungan antarvariabel. Hasil penelitian menunjukkan bahwa literasi gizi berada pada kategori cukup baik (123,73 ± 7,89), namun tidak berhubungan signifikan dengan seluruh parameter metabolik (r –0,218 hingga 0,241; p>0,05). Pola ini mengindikasikan bahwa faktor budaya, aktivitas fisik agraris, serta pola konsumsi tradisional kemungkinan berperan lebih dominan dalam membentuk profil metabolik masyarakat Badui dibandingkan literasi gizi formal.

Vorella Hani Agustin; Virginia Alegra Prameswari; Yosia Putra Pratama; Dwi Yogo Budi Prabowo; Swanny Trikajanti Widyaatmadja +3 more

Jurnal Riset Rumpun Ilmu Kesehatan 2025 Pusat riset dan Inovasi Nasional

Diabetes mellitus is a chronic metabolic disease characterized by elevated blood glucose levels due to impaired insulin secretion or function. The prevalence of diabetes continues to increase in Indonesia, particularly among adults and the elderly, requiring comprehensive and sustainable management. Diabetes management is not limited to pharmacological therapy but also includes non-pharmacological approaches such as dietary management, physical activity, and health education. One form of physical activity recommended for diabetes sufferers is diabetes exercise. This study aims to determine the effect of diabetes exercise on reducing blood glucose levels in diabetes mellitus patients enrolled in the Chronic Disease Management Program (Prolanis) at the Gunungpati Community Health Center (Puskesmas). The study used a quantitative approach with a one-group pretest-posttest pre-experimental design. A total of 30 respondents were randomly selected from the Prolanis patient population, and blood glucose levels were measured before and after the diabetes exercise intervention. The intervention was carried out routinely and structured over a certain period. The analysis using the Wilcoxon Signed Ranks test showed a statistically significant decrease in blood glucose levels after diabetes exercise, with a p-value of 0.000 (p < 0.05). The average blood glucose level decreased from 260.27 mg/dL to 211.33 mg/dL. This study concluded that diabetes exercise is effective as a non-pharmacological intervention in helping control blood glucose levels. Therefore, routine implementation of diabetes exercise in primary healthcare facilities needs to be promoted as a simple, effective, and affordable promotive and preventive strategy.  

Hoyriyetus Sholehah; Dodik Hartono; Achmad Kusyairi

Jurnal Ilmu Keperawatan dan Kebidanan 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

Diabetes Mellitus is a disease characterized by hyperglycemia and metabolic disorders in the body which are associated with a lack of insulin secretion. Generally, DM therapy can be carried out using pharmacology and non-pharmacology. Non-pharmacological therapy that can be carried out is AAROM therapy and a low carbohydrate diet. The aim of this study was to determine the effect of AAROM therapy and a low carbohydrate diet on reducing blood glucose levels in elderly people suffering from type 2 DM in Ngepoh Village. This type of research isPre-experimentalby designTwo groups pre-post test. The total population was 90 respondents and the sample size was 33 elderly respondents suffering from type 2 DM in Ngepoh Village which were taken by purposive sampling. Data collection in this research used questionnaires and observation sheets. Analyzed with SPSS 20 using testsMan Whitney. The results of this study showed that the average blood glucose value in the control group was 282 mg/dl pre glucose and 177 mg/dl post glucose. Meanwhile, the mean blood glucose value in the treatment group with pre glucose was 295 mg/dl and post glucose was 144 mg/dl and there was an effect of AAROM therapy and a low carbohydrate diet on reducing blood glucose levels in elderly people suffering from type 2 DM in Ngepoh Village (ρ = 0.000 < α= 0.005) So type 2 DM sufferers are expected to be able to control blood glucose, one of them is by doing AAROM Therapy and a low carbohydrate diet. AAROM therapy can reduce insulin resistance, making it easier for glucose to enter cells, preventing obesity, and improving venous blood flow.

Dian Ramadhan; Dheni Koerniawan

Jurnal ilmu Kesehatan Umum 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

Background: Diabetes mellitus is a metabolic disorder caused by increased blood glucose levels in the bloodstream or hyperglycemia, which is caused by abnormalities in insulin secretion or abnormalities in insulin work. Physical activity can also affect blood sugar levels, one of which is the physical activity of foot exercises which is recommended for people with diabetes mellitus. Objective: To determine the effectiveness of foot exercise activities in reducing blood glucose levels in diabetes mellitus sufferers. Method: The research design used a descriptive method with a nursing process approach with a case study design. This research was carried out by providing foot exercise physical activity intervention for 3 consecutive days. Results: Based on the application of EBP, the results obtained from 3 patients who experienced a decrease in blood glucose levels before and after being given foot exercise therapy, there was an average decrease in P1 of 13.66mg/dL, P2 of 11.66mg/dL, and P3 of 13mg/dL every day. Suggestion: It is hoped that the results of this research can provide insight to diabetes mellitus sufferers in efforts to manage diabetes mellitus with foot exercise physical activity and be able to apply it.

Nurul Azmi Fauziyah; Sandra Pebrianti; Sri Hartati Pratiwi

Jurnal Ilmu Kesehatan 2024 Lembaga Pengembangan Kinerja Dosen

Diabetic ketoacidosis (DKA) is a life-threatening form of diabetes mellitus emergency. Rapid and appropriate management is needed to prevent worsening condition. Fluid management in DKA is important to improve tissue perfusion, correct electrolyte imbalance, reduce blood glucose concentration and counterregulatory hormones. This case report aims to describe the fluid management in a client with instability of blood glucose levels in DKA. A 42-year-old woman was rushed to the emergency room with decreased consciousness for 3 hours. Laboratory examination results: blood glucose >600mg/dL, Base Excess <-30mmol, urine ketones +3, urine protein +2, urine glucose +4, pH 6.8, HCO3 1.9mmol/L. The client had unstable blood glucose levels while in the treatment room. Fluid management was performed by combining 0.9% NaCl, WIDA 2A, 40% dextrose bolus, and continuous insulin drip, that was adjusted according to the client's blood glucose level. After receiving fluid management, the client's blood glucose levels are stable in the range of 100 - 200mg/dL on the fifth day until the client recovered. Providing fluid management tailored to the management of DKA and client needs can improve the stability of blood glucose levels so that this fluid management intervention can be utilized for DKA clients with similar complaints.

Agus Waluyo Sejati; Fida’ Husain; Suciana Ratrinaningsih

Jurnal Kesehatan dan Kedokteran 2024 Lembaga Pengembangan Kinerja Dosen

Background: Type 2 diabetes mellitus is a type of metabolic disorder characterized by hyperglycemia which leads to serious complications. One physical activity that can be applied is progressive muscle relaxation, which focuses on sequentially tightening and relaxing muscle groups resulting in controlled blood glucose levels so that holistic treatment is needed. Objective: To determine the results of the application of Progressive Muscle Relaxation (PMR) to reduce blood glucose levels in people with type 2 diabetes mellitus at RSUD Dr. Moewardi Surakarta. Method: This research is a type of qualitative descriptive research with a case study approach (Case Study). The design for this application was a control group design which was applied to 1 respondent with Diabetes Mellitus Type 2. Results: Based on the results of this application, it was found that blood glucose levels decreased after Progressive Muscle Relaxation was carried out, which was indicated by the number of high glucose levels decreasing. Comparison before and after applying Progressive Muscle Relaxation, before being given the application of PMR high blood sugar levels were 415 mg/dl and after being given the application of PMR 2 times a day (morning and evening) for 3 consecutive days normal blood sugar levels were 173 mg/dl etc. Conclusion: Blood sugar levels before the application were given were high and after the application was given the patient's blood sugar levels were normal.

Yulianti Ely; Zulfikar Peluw

DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan 2024 International Forum of Researchers and Lecturers

Hyperglycemia is the main characteristic of diabetes mellitus (DM) disease characterized by an increase in blood sugar levels above the normal threshold (200 mg/dL) which can be caused by relative or absolute insulin deficiency, or by cellular resistance to insulin action. Hyperglycemia is one of the metabolic disorders with a high risk of hospitalization and disability, especially in patients with diabetes mellitus with an increasing prevalence. To provide an overview of the implementation of health education through leafleat media to improve the stability of blood glucose levels in patients with diabetes mellitus at the GPM Ambon Source of Life Hospital. Subject Research Patient was Mrs. R in the Atalia Room of Sumber Hidup Hospital on May 16-17, 2022. The research found that Mrs. R did not understand several things about the stability of blood glucose levels. The nursing diagnosis raised in the patient is the risk of blood glucose instability. Nursing action is to provide health education about the lack of exposure to information about Hyperglycemia, Mrs. R can understand the stability of blood glucose levels. Based on the results of research conducted in the Atalia room at the GPM Ambon Living Source Hospital on May 16-17, 2024 in patient "Mrs.R" with DM, it can be concluded that providing health education using Leaflet media in overcoming the lack of exposure to information regarding Hyperglycemia in Diabetes Militus patients is very important.

Nunung Sri Haryati; Siti Robeatul Adawiyah; Hasan Basri

DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan 2024 International Forum of Researchers and Lecturers

Background: Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia due to abnormalities in insulin secretion, insulin action, or insulin secretion. The prevalence of diabetes in the population aged 20-79 years based on region in 2019 globally reached 8.3% and Southeast Asia was in 3rd place (11.3%). Indonesia is ranked 7th among the 10 countries with the highest number of sufferers, namely 10.7 million. From the data obtained by the author, diabetes mellitus is one of the 10 biggest diseases in the Periuk Jaya Health Center, the number of which increases every year. From data obtained in 2023, January-December, there were 672 diabetes mellitus sufferers. To avoid disease complications in diabetes mellitus sufferers, it is necessary to control or reduce blood sugar levels. Controlling blood sugar levels for diabetes mellitus, apart from using diabetes medicines, you can also use more natural traditional plants, namely consuming red betel leaves. Method: Case study using nursing care for Mrs. S by giving boiled red betel leaves for 7 days. Result: This red betel leaf decoction provides significant results for controlling blood sugar levels for diabetes mellitus sufferers.

Novita Sariayu Sitompul; Meynur Rohmah; Dwi Wahyuni

DIAGNOSA: Jurnal Ilmu Kesehatan dan Keperawatan 2024 International Forum of Researchers and Lecturers

Background: Type 2 diabetes mellitus is a metabolic disorder characterized by an increase in blood sugar due to decreased insulin secretion by pancreatic beta cells or insulin resistance. Difficulty controlling blood sugar levels is a problem experienced by every person with type 2 diabetes mellitus. Several reasons cause uncontrolled blood sugar levels, such as the patient not wanting to exercise, poor diet and negligence in treatment. Management of diabetes mellitus can be done with non-pharmacological therapy in the form of physical exercise. Physical activity will make the body's metabolism work more optimally which will result in blood glucose levels being controlled so that holistic treatment is needed. One of the non-pharmacological physical exercise therapies that can be given to diabetes mellitus sufferers is progressive muscle relaxation techniques. Research method: Implementing Progressive Muscle Relaxation Therapy in Type II Diabetes Mellitus patients to reduce Blood Glucose Levels. Research results: The results of implementation and evaluation for 3 days with Progressive Muscle Relaxation Therapy intervention showed objective and subjective changes in Type II Diabetes Mellitus patients as well as changes in blood glucose levels before and after being given Progressive Muscle Relaxation Therapy. Conclusion: There is a decrease in Blood Glucose Levels after Progressive Muscle Relaxation Therapy.

Magenda Bisma Yudha; Nur Intan Kartika Sari

Jurnal Ilmu Keperawatan dan Kebidanan 2024 Asosiasi Riset Ilmu Kesehatan Indonesia

Background: One of the non-communicable diseases (NCDs) that has received a lot of attention is Diabetes Mellitus. Diabetes management is divided into two ways. The first way is with non-drug therapy (non-pharmacological) and second with drug therapy. Drug therapy in the form of oral hypoglycemic drugs or insulin. Non-pharmacological methods with food planning and physical exercise. The type of light physical exercise recommended for patients with type II diabetes mellitus is walking and brisk walking. Objective: To determine the effect of brisk walking to reduce blood glucose levels in patients with type 2 diabetes mellitus. Methods: This review uses the literature review method. Searches were conducted in PubMed, Garuda, and Google Scholar. The search strategy used keywords with "brisk walking", "physical exercise", "glycemic control", "diabetes mellitus, type II",. Results: Seven articles were reviewed in this literature review. Six articles discussed brisk walking, one article discussed the difference in glycemic control in low - high intensity interval training with endurance training. The overall results of this review show that doing physical activity brisk walking has an effect in reducing blood glucose levels, reducing blood glucose levels by 49.75 mg/dL. Physical activity sessions can be done for 3 - 7 sessions per week with a duration of 15 - 60 minutes. Conclusion: The effect of brisk walking is proven to reduce blood glucose levels in patients with type 2 diabetes mellitus.

Ma’rifat Istiqa Mukty

Jurnal ilmu Kesehatan Umum 2023 Asosiasi Riset Ilmu Kesehatan Indonesia

Oxidative stress is a condition where there is an imbalance between oxidants and antioxidants in the body which can trigger psychological stress. Oxidative stress can be reduced by consuming exogenous antioxidants (antioxidants from outside), where green tea is thought to be able to reduce oxidative stress. The aim of this study was to examine the effect of steeping green tea on blood glucose and Malondialdehyde (MDA) levels in male Wistar Strain white rats exposed to psychological stress. The design used in this research was Randomized Post Test Only Group Design. There were 5 groups of mice; 2 are a normal control group and a stress control group, and 3 treatment groups. Previously, the mice were given psychological stress 1 x 24 hours in the form of disturbed sleep patterns, so that the experimental animals experienced oxidative stress, then green tea was given to the treatment group with a single dose of 3.6 ml/head in the 1st hour in the group. treatment 1, 6th hour in treatment group 2, and 24th hour in treatment group 3. Statistical analysis used the Manova test.  Based on statistical analysis, it shows that there was a decrease in blood glucose and Malondialdehyde (MDA) levels in all treatment groups given exposure to psychological stress and steeping green tea.  A single dose of green tea brewing in experimental animals experiencing oxidative stress was proven to be able to neutralize oxidative stress in the 1st hour after administration of green tea brewing and the antioxidant activity still lasted up to 24 hours.

Warina Hotmatiur Br Sihaloho; Muhammad Anis Taslim; Tunik Saptawati

Jurnal Ilmu Kesehatan dan Gizi 2023 Pusat Riset dan Inovasi Nasional

Diabetes Mellitus is a metabolic disease indicated by hyperglycemia. This matter occurs due to the incapability of the pancreas to secret the insulin, the interrupted insulin performance, or the existence of both problems. Poor sleeping quality influenced the blood glucose level in the body. Normal individuals have blood glucose levels between 65 and 120 mg/dl after waking up. This research determined the blood glucose levels and the sleeping quality of diabetes mellitus type 2 patients. This quantitative research applied the analytical descriptive design with the cross-sectional approach. The sample consisted of 40 respondents taken by purposive sampling technique. The applied measuring instrument was the Pittsburgh Sleep Quality Index, PSQI. The Spearman Rank test obtained a p-value of 0.000 lower than 0.05. Thus, the result accepts Ha, indicating a significant correlation between blood glucose and the sleeping quality of diabetes mellitus type 2 patients with r = 0.786. The r-value had a negative correlation indicating a strong correlation between glucose level and the sleeping quality of the patients. If the blood glucose was abnormal, the sleeping quality would be poor and vice versa. The researcher recommends future researchers promote quantitative research to examine the influential factors of diabetes mellitus type 2 patients' quality.

Hirmawati Hirmawati; Abdul Kadim Masaong; Fadli Syamsuddin

Jurnal Inovasi Riset Ilmu Kesehatan 2023 Pusat Riset dan Inovasi Nasional

  Pada penderita diabetes melitus yang memiliki pengetahuan yang baik memungkinkan penderita dapat mematuhi segala apa yang telah dianjurkan oleh petugas kesehatan seperti diet yang telah ditentukan untuk penderita diabetes melitus tersebut.Penelitian ini untuk menggambarkan kepatuhan diet pencegahan DM pada pasien DM di Puskesmas Tilamuta. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan metode Deskriptif. Hasil menunjukkan bahwa  responden berdasarkan Pengetahuan terhadap Kepatuhan Diet, terbanyak Pada Kategori sedang dengan jumlah 27  responden (70.0%), Responden berdasarkan Sikap terhadap Kepatuhan Diet, terbanyak Pada Kategori rendah dengan jumlah 18  responden (60.0%), Responden berdasarkan Motivasi terhadap Kepatuhan Diet terbanyak Pada Kategori rendah dengan jumlah 18  responden (60.0%), Responden berdasarkan Dukungan Keluarga terhadap Kepatuhan Diet, terbanyak Pada Kategori rendah dengan jumlah 27  responden (90.0%).Saran dalam penelitian ini diharapkan Responden lebih meningkatkan Pengetahuan, sikap, motivasi dan dukungan keluraga dalam menjalankan diet DM agar kadar glukosa darah tetap terkendali untuk mencegah komplikasi.      

Gledis Riskilawati Laboro; Andi Akifa Sudirman; Andi Nur Aina Sudirman

Journal of Educational Innovation and Public Health 2023 Pusat Riset dan Inovasi Nasional

Penggunaan bahan alami sebagai terapi alternatif sangat membantu untuk menekan biaya terapi dan perawatan bagi klien diabetes mellitus. Salah satu jenis terapi yang paling baik dan mudah didapat untuk penderita diabetes mellitus adalah susu kedelai. Tujuan penelitian ini untuk pengaruh pemberian susu kedelai terhadap kadar gula pada penderita diabetes mellitus. Jenis penelitian yang digunakan adalah penelitian kuantitatif dengan desain penelitian quasy experimen. Penelitian ini dilaksanakan di wilayah kerja Puskesmas Telaga Biru. Analisis data menggunakan uji paired sample t test. Pengambilan sampel dilakukan dengan tehnik purposive sampling. Jumlah sampel sebanyak 30 orang. Berdasarkan hasil uji analisis didapatkan nilai p-value = 0,000 < dari nilai α 0,05, artinya Ha diterima dan H0  ditolak, maka ada pengaruh pemberian susu kedelai terhadap penurunan kadar gula darah pada penderita diabetes mellitus. Kesimpulannya, susu kedelai mengandung protein, isoflavin dan serat yang tinggi yang bermanfaat terhadap penurunan kadar glukosa darah. Saran diharapkan dapat meningkatkan asuhan keperawatan untuk masyarakat berupa terapi nonfarmakologi yang baik dikonsumsi untuk penderita diabetes mellitus.    

Jayanti Djrami; Amelia Niwele; Novita Polpoke

Jurnal Riset Rumpun Ilmu Kesehatan 2023 Pusat riset dan Inovasi Nasional

Diabetes mellitus merupakan penyakit yang ditandai dengan peningkatan kadar glukosa darah yang diakibatkan oleh kurangnya insulin atau terjadinya resistensi insulis. Daun kersen (Muntigua calabula L) merupakan salah satu tanaman herbal yang berfungsi sebagai antidiabetes. Untuk mengetahui kandungan metabolit sekunder yang ada pada daun kersen dan mengetahui apakah daun kersen efektif terhadap penurunan kadar glukosa darah serta konsentrasi berapakah yang paling efektif terhadap penurunana kadar glukosa darah pada mencit (Mus muscullus) yang diinduksi aloksan. Maka metode yang digunakan ialah metode eksperimental dengan rancangan penelitian adalah rancangan acak lengkap. Dilakukan pengujian fitokimia untuk melihat kandungan metabolit sekunder daun kersen mengandung senyawa tanin, flavanoid, saponi dan trepenoid. Setelah itu dilakukan pengukuran pada mencit yang dibagi menjadi 5 kelompok dengan akuadest sebagai control negatif, metformin sebgai control positif dan ekstrak daun kersen dengan konsentrasi yg berbeda-beda 65%, 70% dan 75% kemudian didapatkan hasil dari penelitian, setelah data diuji mengunakan uji-T (test uji) dan diuji mengunakan paired sampel test, dari hasil uji diketahui bahwa nilai p=0,003 yang berarti nilai tersebut lebih kecil dari nilai probalitas yakni ,0,05 jadi disimpulkan bahwa terdapat perbedaan yang signifikan antara sebelum dan sesudah pemberian ekstrak daun kersen terhadap pengaruh penurunankadar gula darah dilihat dari nilai signifikanya 0,003. Sehingga didapatkan bahwa ekstrak metabolit sekunder daun kersen dapat menurunkan kadar gula darah dan konsentrasi yang paling efektif dalam menurunkan kadar gula darah adalah konsentrasi 70%.

Mamay Mamay; Lia Mar’atiningsih; Aceng Ali Awaludin; Regawati Rizkina

Student Scientific Creativity Journal 2023 Pusat Riset dan Inovasi Nasional

Diabetes mellitus yang tidak dikontrol dengan baik akan menghasilkan berbagai komplikasi penyakit salah satunya yaitu dislipidemia. Dislipidemia adalah suatu kelainan metabolisme pada lipid yang ditandai dengan tingginya kolesterol total dan trigliserida. Jika tubuh kelebihan kadar trigliserida akan mengakibatkan resistensi insulin sehingga metabolisme gula darah akan terganggu. Pada penelitian ini bertujuan untukk mengetahui korelasi kadar trigliserida dan GDP pada Penderita DM tipe 2 di RSUD dr Slamet Garut. Sampel dalam penelitian ini adalah 28 orang penderita DM tipe 2 telah berpuasa 8-12 jam. Pemeriksaan glukosa darah puasa dengan metode GOD – PAP dan trigliserida dengan metode GPO -PAP. Dari hasil penelitian terdapat 5 orang (17,9%) responden mempunyai kadar GDP normal dan 23 (82,%) responden mempunyai kadar GDP tinggi dan 11 (39,3%) responden mempunyai kadar trigliserida normal dan 17 responden (60,7) mempunyai kadar trigliserida tinggi. GDP dan Trigliserida menunjukan pola positif, artinya semakin tinggi GDP, maka kadar trigliserida pada penderita DM tipe 2 semakin tinggi. Hubungan tersebut sedang dengan Pearson’s correlation sebesar 0.427. Hasil statistic menunjukan p=0.024 yang berarti p<0.05 sehingga dapat disimpulkan ada hubungan yang bermakna antara kadar GDP dan trigliserida pada pasien DM tipe 2 di RSUD dr Slamet

Hartono, Dodik

Jurnal Pengabdian Kepada Masyarakat Sisthana 2022 Stikes Kesdam IV/Diponegoro Semarang, Indonesia

Diabetes melitus merupakan penyakit kronis yang membutuhkan supervisi medis berkelanjutan serta edukasi perawatan secara mandiri, apalagi dalam masa pandemic covid. Pada masa pandemi covid seseorang yang memiliki penyakit bawaan memiliki resiko tinggi untuk lebih cepat tertular penyakit covid dan bisa menyebabkan kematian. Maka dari itu penderita diabetes mellitus perlu melakukan manajemen yang baik untuk menjaga kesehatannya, meskipun tidak datang ke pelayanan Kesehatan. Manajemen diabetes yang dapat dilakukan meliputi kontrol glukosa darah, pola makan, olahraga, minum obat teratur dan perawatan kaki. Tujuan kegiatan pengabdian kepada masyarakat ini untuk meningkatkan pengetahuan, kemampuan dan keterampilan pasien dalam penatalaksanaan diabetes dengan cara manajemen diabetes mellitus. Metode yang dilakukan dalam kegiatan ini dengan cara memberikan konseling manajemen diabetes mellitus kepada pasien saat pelaksanaan posyandu di balai Desa Karangbong. Pemberian edukasi dilakukan dengan 2 metode yaitu dengan memberikan edukasi secara langsung bersamaan dan secara individu kepada pasien. Kegiatan ini dilakukan oleh 3 tim dosen dan 5 mahasiswa keperawatan. Hasil dalam kegiatan pengabdian kepada masyarakat ini penderita diabetes dapat memahami dan meningkatkan kemampuannya tentang manajemen penatalaksanaan diabetes mellitus secara mandiri, khususnya dimasa pandemi. Pasien diabetes mellitus dapat melakukan melakukan manajemen diabetes mellitus dirumah dengan cara melakukan pengecekan kadar glukosa darah seminggu sekali, selalu melaksanakan aktivitas fisik, menjaga pola makan, minum obat sesuai aturan dan melakukan perawatan kaki setiap hari untuk mencegah terjadinya luka ulkus diabetes.   

Ria Ceriana; Nova Zarmi Putri; Cut Yuliana

Jurnal Riset Rumpun Ilmu Kesehatan 2022 Pusat riset dan Inovasi Nasional

Kulit buah rambai (Baccaurea motleyana) merupakan salah satu bagian tumbuhan yang dapat digunakan untuk menurunkan kadar glukosa darah pada mencit yang telah dinduksi aloksan. Tujuan penelitian ini untuk mengetahui keamanan dalam penggunaan tumbuhan sebagai obat herbal agar tidak menimbulkan efek berbahaya yang tidak diinginkan, maka perlu dilakukan uji toksisitas pada hati mencit. Hati merupakan organ tubuh sasaran zat toksik karena memegang peranan penting dalam proses metabolisme tubuh. Rancangan penelitian dalam penelitian ini ialah Rancangan Acak Lengkap (RAL) dengan 6 perlakuan dan 4 ulangan. Perlakuan terdiri kontrol negatif (akuades), kontrol positif (Glibenklamid), dan ekstrak etanol      kulit buah rambai dengan dosis bertingkat 200 mg/kgBB, 400 mg/kgBB, 800 mg/kgBB, 1600 mg/kgBB yang diberikan secara oral. Data dianalisis menggunakan analisis varians (ANAVA) dan apabila perlakuan berpengaruh maka diuji lanjut menggunakan uji jarak berganda Duncan dengan taraf kepercayaan 5%. Hasil pengamatan menunjukkan pemberian ekstrak etanol kulit buah rambai berpengaruh nyata terhadap kerusakan pada sel-sel hati mencit diabetes berupa hiperemi dan hemoragi. Perlu adanya penelitian lebih lanjut mengenai uji toksisitas sub kronis dan kronis terhadap pemberian ekstrak etanol kulit buah rambai. Penelitian lanjut yang dapat dilakukan yaitu pengujian toksisitas pada organ lainnya seperti ginjal, otak, jantung, limpa dan lain-lain.