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Rezky Maulidiya; Ardi Mustakim

Mikroba : Jurnal Ilmu Tanaman, Sains Dan Teknologi Pertanian 2025 Asosiasi Riset Ilmu Tanaman Dan Hewani Indonesia

Vegetable ingredients are natural sources of active compounds that have the potential to be used as control agents for pathogenic microorganisms in various fields, including health and agriculture. This study aims to evaluate the synergistic effect between aloe vera (Aloe vera L.) and bandotan (Ageratum conyzoides L.) extracts on inhibiting the growth of pathogenic bacteria in different media. Aloe vera extract is obtained using the infundation method, while bandotan extract is obtained using the maceration technique. The concentrations tested were 30%, 45%, and 60% for each extract, as well as a combination of both. Testing was carried out on two main applications: as an antiseptic hand sanitizer by testing germ colonies using Plate Count Agar (PCA), and as a bacteria control Erwinia carotovora, the cause of carrot tuber rot, using the Path Ways Analysis test. The results showed that the combination of aloe vera and bandotan extracts had more significant inhibitory effectiveness than single extracts in both applications. A combination concentration of 60% gave the best results with a reduction in bacterial colonies of up to 90%. The mechanism of action of active compounds such as flavonoids, phenolics and saponins in this vegetable extract plays an important role in damaging bacterial cell membranes and inhibiting the metabolism of microorganisms. This research confirms the potential of using local plant materials as an environmentally friendly and economical solution for controlling pathogenic bacteria in the health and agricultural sectors.

Refa Rahmaddiansyah; Salsabila Syafna Aulia; Sukarsi Rusti

International Journal of Medicine and Health 2023 Lembaga Pengembangan Kinerja Dosen

Dengue Hemorrhagic fever (DHF) is caused by a dengue virus that spreads through the bite of the Aedes aegypti mosquito, which breeds a lot in densely populated areas with humid and warm climates. Anti-mosquito drugs in the form of burns, sprays, lotions, or other types are already widely used, but these anti-mosquito drugs are not entirely beneficial. This research is purely experimental research with Post-test Only Control Group Design by making air spray solution products from noni leaf infusion and cananga flower, which are analyzed descriptively and analytically. Experiments carried out with Randomized Complete Design 1 time repetition to analyze effectiveness. The study used two factors: treatment (P) using infusion products while the control (K) using distilled water. From the results of mixing, it was obtained as much as 400 ml of infusion solution. Obtained in each measurement, there was a reduction in live larvae until the last measurement. Noni leaf contains five flavonol glycosides (flavonoid compounds) as respiratory poisons and a combination of saponins and tannins as stomach poisons that have the killing power against the death of Aedes aegypti larvae. Cananga flower extract itself can resist mosquitoes because of the content of linalool, geraniol and eugenol. This makes a change in the larvae's behavior, where the previously active movement will be slow and eventually will die.