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Ritha Mariati Sembiring; Eka Permata Sari Br. Sihombing; Indah Juni Florida Daeli; Maria Aloysia O. W. L. Masa; Grace Krishna Angelica Gea +1 more

Jurnal Riset Rumpun Ilmu Kesehatan 2026 Pusat riset dan Inovasi Nasional

Gout arthritis is a disease characterized by sudden inflammation of the joints due to high levels of uric acid in the body (hyperuricemia). This condition is marked by acute episodes of joint inflammation, often affecting a single joint and preceded by asymptomatic periods of varying duration. Older adults represent the final stage in the human lifespan and experience the natural aging process. This study employed an analytic survey design with a cross-sectional approach. The purpose of this study was to determine the relationship between gout arthritis pain and the level of independence in activities of daily living among patients at the Helvetia Public Health Center. The results showed that the majority of older adults in the working area of UPT Puskesmas Helvetia experienced high levels of pain, with 73 respondents reporting severe pain. Meanwhile, most respondents demonstrated independence in their daily activities, with 72 categorized as independent. The findings indicate a significant relationship between gout arthritis and the level of independence in activities of daily living among older patients at the Helvetia Public Health Center.

Rachmawaty M.Noer; Yulianti Wulandari; Alvany Gustira Salman

Jurnal Ilmu Kesehatan Umum, Psikolog, Keperawatan dan Kebidanan 2026 Asosiasi Riset Ilmu Kesehatan Indonesia

Gout arthritis, or often called gout, is a type of arthritis caused by the accumulation of uric acid crystals in the joints and surrounding tissues. Arthritis itself is a term used to describe inflammation of the joints. The process of gout begins with an increase in uric acid levels in the blood, called hyperuricemia. Gout arthritis sufferers in the world affect approximately 10% to 25% of the world's population, the WHO prevalence of gout arthritis in the world is 34.2%. The type of research used in this study is quantitative research using a quasi-experimental research method, namely the pre-posttest control one group design method. This study is a study conducted on 1 group using an intervention without a comparison. This study has been conducted with a total of 20 elderly people who meet the inclusion and exclusion criteria. It is known that the Sig. (2-tailed) value of 0.00 is greater than 0.05. then there is a significant difference between the results before and after the warm cinnamon water compress. So it can be concluded that there is an effect of warm cinnamon compresses (Cinnamomun Burmannii) on gout arthritis in the elderly at the Sei Pancur Community Health Center.

Irfan Darfika Lubis; Rahmanda Artamevia; Eka Febriyanti; Yuanita Mayasari Aritonang

Jurnal Riset Rumpun Ilmu Kedokteran 2026 Pusat riset dan Inovasi Nasional

Background: Hyperuricemia represents a medical condition marked by elevated concentrations of uric acid within the bloodstream, potentially triggering gout alongside various metabolic disorders. Central obesity has been identified as a contributing factor to rising uric acid concentrations, measurable through waist circumference assessment. Methods: An analytic observational design utilizing a cross-sectional approach was employed in this investigation, encompassing 100 male participants characterized by sedentary lifestyles who were employed as office workers in Medan City, North Sumatra Province. Waist circumference measurements were obtained using a flexible measuring tape, while uric acid concentrations were determined through Point of Care Test (POCT) devices. Statistical evaluation was conducted via the Chi-Square test, applying a significance threshold of 0.05. Results: Among all participants, 64 individuals (64%) exhibited waist circumference measurements indicative of central obesity, whereas 56 individuals (56%) demonstrated hyperuricemic conditions. Statistical evaluation revealed a significant association between waist circumference measurements and uric acid concentrations, evidenced by a p-value of 0.000 (p < 0.05). Conclusion: A meaningful correlation exists between waist circumference and uric acid concentrations among males engaged in sedentary occupations.

Besse Illang Sari; Siti Khairunnur; Andi Yanti Puspita Sari; Muhammad Mulyadi Nahrun

Jurnal Riset Rumpun Matematika dan Ilmu Pengetahuan Alam 2025 Pusat riset dan Inovasi Nasional

Lemongrass (Cymbopogon citratus) is a plant known to contain various bioactive compounds with potential antioxidant properties as well as xanthine oxidase (XO) inhibitory activity. This study aimed to evaluate the phytochemical content, antioxidant activity, and XO inhibitory potential of ethanol extracts from the leaves, stems, and their combination. Phytochemical screening revealed that all extracts contained alkaloids, flavonoids, and terpenoids, while phenolic compounds were detected only in the leaf extract and the combined leaf–stem extract. Antioxidant activity assays demonstrated that all extracts exhibited very strong antioxidant activity, with IC₅₀ values below 50 ppm, indicating a significant potential to scavenge free radicals. In the XO inhibition assay at a concentration of 200 ppm, the ethanol extract of lemongrass stems showed the highest inhibitory activity at 81.37%, followed by the leaf extract at 48.08% and the combined leaf–stem extract at 33.65%. Overall, these findings suggest that the ethanol extract of lemongrass stems is the most promising natural source of antioxidants and has the greatest ability to inhibit xanthine oxidase activity, indicating its potential development as a functional ingredient for health applications.

Susy Olivia Lontoh; Song, Chrismerry; Ernawati Ernawati

Jurnal Hasil Kegiatan Bersama Masyarakat 2025 Asosiasi Riset Ekonomi dan Akuntansi Indonesia

Non-communicable diseases (NCDs) are the leading causes of morbidity and mortality, particularly among older adults. Integrated Development Posts for Non-Communicable Diseases (Pos Pembinaan Terpadu Penyakit Tidak Menular / Posbindu PTM) play a crucial role in the early detection of NCD risk factors at the community level. This activity aimed to conduct NCD risk factor screening through the measurement of blood pressure, random blood glucose, total cholesterol, and uric acid levels, as well as to provide health consultations for participants of Posbindu Rosella, South Kembangan. The activity was conducted in November 2025 using a descriptive design. A total of 30 Posbindu participants were involved. Health examinations included blood pressure, random blood glucose, total cholesterol, and uric acid measurements. Data were analyzed descriptively and classified into normal and abnormal categories based on clinical guidelines. The majority of participants were female (80%), with a mean age of 60.5 ± 9.7 years. The mean systolic blood pressure was within the hypertensive range. Approximately 50% of participants had impaired glucose regulation, 60% experienced hyperuricemia, and 40% had total cholesterol levels classified as borderline or higher.  Health screening activities at Posbindu revealed a high prevalence of NCD risk factors among participants. Posbindu plays an essential role in early detection and community-based prevention of non-communicable diseases.

Tjie Haming Setiadi; Alexander Halim Santoso; Edwin Destra; Steven Hizkia Lucius; Ryan Dafano Putra Mahendri +1 more

Karunia: Jurnal Hasil Pengabdian Masyarakat Indonesia 2025 Fakultas Teknik Universitas Maritim AMNI Semarang

Uric acid is the final product of purine metabolism, which can increase due to high purine intake or impaired renal excretion. Accumulation of uric acid in the body is at risk of causing joint inflammation and other metabolic disorders. Early detection and dietary education are strategic steps to prevent complications of hyperuricemia. This activity uses the Plan-Do-Check-Act (PDCA) approach by examining uric acid levels using POCT and education on managing purine consumption. The examination was carried out on 62 adult participants. Educational leaflets were delivered directly and individually to each participant. All participants had uric acid levels in the normal range (median 4.2 mg/dL), with the lowest value of 3.5 mg/dL and the highest 6.5 mg/dL. Most participants were women and were in the middle to elderly age group. Although no cases of hyperuricemia were identified, preventive education remains essential to maintain uric acid levels within optimal ranges and reduce future metabolic risks. Lifestyle interventions focusing on diet and hydration are critical for sustainable uric acid control and long-term health outcomes.   Keywords: Uric Acid, Purine, Hyperuricemia, Diet, Nutrition Education

Olivia Happy Novita; Razoki Lubis; Finna Piska

Jurnal ilmu Kesehatan Umum 2025 Asosiasi Riset Ilmu Kesehatan Indonesia

The use of drugs for hyperuricemia and gout arthritis is given for conditions that cause higher purine metabolism in the body. This study was conducted at RSU Royal Prima Marelan to determine the pattern of drug use for hyperuricemia and gout arthritis due to inflammation caused by uric acid deposits in the joints. Data collection in this study was carried out retrospectively by collecting medical records of patients with hyperuricemia and gout arthritis. The descriptive method used in this study was a cross-sectional plan. Qualitative descriptive analysis was applied to the data. Tables or narratives were used to present the data in this study. The results showed that 30 patients out of 50 were male and 20 were female. The results of the evaluation of the rationality of drug use for hyperuricemia and gout arthritis showed that patients who were given several versions of drugs with the xanthine oxidase inhibitor group 64% were allopurinol with patients with the most appropriate indications, the right patient, and the right dose of 96%.

Irma Yunawati; Nurnashriana Jufri; Wa Ode Salma; Minnati Zulfa Anika; Cantika Alisyah +3 more

Karunia: Jurnal Hasil Pengabdian Masyarakat Indonesia 2025 Fakultas Teknik Universitas Maritim AMNI Semarang

Uric acid is the end product of purine metabolism which can cause hyperuricemia if levels increase. Hyperuricemia, if left untreated, can cause joint inflammation, pain, and various other health problems. This study aims to evaluate Halu Oleo University students' understanding of gout and its impact on health. Using a quantitative approach and analytical descriptive design, this research involved 50 randomly selected respondents. Examination of uric acid levels is carried out by taking blood samples using the Nesco Multi Check device. The results showed that 70% of respondents had uric acid levels within normal limits, while 30% experienced hyperuricemia, which indicates a potential risk of developing gout. These findings suggest that unbalanced eating patterns, lack of physical activity, and inadequate fluid intake contribute to increased uric acid levels among college students. This research emphasizes the importance of education about healthy eating patterns and an active lifestyle to prevent health problems related to gout.