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Blood is a major component of the homeostatic system that plays an essential role in maintaining the physiological balance of the body. Several blood chemistry parameters, including blood glucose, cholesterol, and blood pH levels, can be used to assess an individual's health condition. Blood glucose is derived from carbohydrate metabolism and serves as the body's primary energy source. Cholesterol is a lipid compound involved in cell membrane formation and hormone synthesis and consists of Low-Density Lipoprotein (LDL) and High-Density Lipoprotein (HDL). Blood pH measurement is used to determine the degree of acidity or alkalinity of the blood, reflecting the body's acid-base balance. This study aims to interpret the results of blood chemical analyses and understand the principles and methods used to determine blood glucose, cholesterol, and pH levels. The research employed a laboratory experimental method by measuring these parameters using blood chemistry testing equipment on blood samples. The results showed that fasting blood glucose was 97 mg/dL, indicating a normal glucose level. In contrast, non-fasting blood glucose was 61 mg/dL, which was below the normal range and indicated hypoglycemia. Blood cholesterol was measured at 139 mg/dL, which remained within the normal range. The blood pH value was 6, indicating a condition of acidosis. These findings highlight the importance of blood chemistry examinations as indicators for evaluating metabolic conditions and overall health status.

Vertigo is a clinical symptom that is often found and can be related to vestibular disorders or systemic conditions such as hypertension. The case report described a 58-year-old female patient who came in with complaints of dizziness that disappeared from 12 hours before admission to the hospital, accompanied by double vision, nausea, severe headache, flatulence, and stiffness of the left shoulder. Physical examination showed increased blood pressure and bidirectional nystagmus on neurological examination. Laboratory tests show mild electrolyte abnormalities and increased cholesterol. The patient was diagnosed with uncontrolled vestibular vertigo et causa hypertension and received intravenous fluid therapy, symptomatic therapy, antihypertensive therapy, and vestibular suppressants. Clinical improvements were obtained during follow-up. Education related to blood pressure control, medication adherence, and lifestyle changes such as low-salt diet settings and stress management is also provided to patients. In addition, periodic monitoring is required to prevent recurrence and further complications. This case emphasizes the importance of identifying hypertension as a contributing factor to vertigo as well as comprehensive management to improve patient outcomes and improve the quality of life of patients.

Cardiovascular dysfunction is a disorder of the blood vessels, such as hypertension, heart failure, and stroke. In 2016, cardiovascular disease was the leading cause of death worldwide, based on data from the World Health Organization (WHO). Coronary Heart Disease (CHD) is the leading cause of death, along with stroke, as shown by the Sample Registration System survey in 2014.This case involves a 64-year-old male, Mr. N, who presented to the emergency department of RSUD dr. Fauziah Bireuen with complaints of chest pain that developed gradually and worsened over the past month. The pain was located across the entire chest and radiated to the back and neck. The pain was described as severe, like being crushed by a heavy load, worsened during strenuous activities such as cutting grass and chopping wood, and relieved when the patient bent forward. The pain could occur at any time, with a Visual Analog Scale (VAS) score of 10 (severe pain). The patient also reported easy fatigue during heavy physical activity over the past month. Laboratory examination revealed elevated leukocytes, mean corpuscular volume (MCV), segmented neutrophils, troponin I, cholesterol, and triglycerides. The patient was diagnosed with extensive anterior ST-elevation myocardial infarction (STEMI) post successful fibrinolytic therapy.

The use of medicinal plants has been an important part of people's lives since the time of our ancestors. Before the advent of modern medicine, people used various types of plants to treat mild to severe illnesses, such as fever, cough, wounds, digestive disorders, and skin diseases. Inventory of medicinal plants plays a very important role in exploring the potential of existing natural resources, especially as an effort to support the development of traditional medicine. The purpose of this study is to identify the types of medicinal plants used by local communities in traditional medicine. The method used in this study is a descriptive method through direct surveys at the research location. The findings obtained in the field concluded that all types of plants mentioned in this study are very beneficial for the people of Duhiadaa District, because they can help in treating various types of diseases experienced by the community. The types of diseases that can be treated include hypertension, gout, stomach acid, cholesterol, kidney disease, diabetes, inflammation, cancer, wounds, diarrhea and digestive disorders.

Lifestyle changes, such as smoking habits, low physical activity, and suboptimal sleep patterns, have the potential to affect various health indicators. However, empirical evidence showing a direct link between lifestyle factors and objective health indicators still shows varying results. This study aims to analyze the relationship between lifestyle factors and health indicators in adult respondents, in an effort to provide an empirical picture of behavioral factors related to health conditions. This study used a quantitative approach with a cross-sectional observational analytic design. Data were obtained from 94 respondents who had complete lifestyle data and health examination results. Lifestyle factors analyzed included smoking habits, exercise frequency, and sleep duration, while health indicators included body mass index (BMI), systolic and diastolic blood pressure, blood sugar levels, cholesterol, uric acid, and pulse rate. Data analysis was performed using descriptive statistics, the Shapiro–Wilk normality test, and the Spearman correlation test according to the characteristics of the data distribution. The results showed that smoking habits were significantly associated with diastolic blood pressure (p < 0.05), exercise frequency was significantly associated with BMI and systolic blood pressure (p < 0.05), and sleep duration was significantly associated with uric acid levels (p < 0.05). Meanwhile, the relationship between lifestyle factors and other health indicators did not show statistical significance. These findings indicate that the influence of lifestyle on health is specific to certain indicators and is not evenly distributed across all health parameters. This study concludes that identifying lifestyle factors relevant to certain health indicators is important as a basis for formulating more targeted health promotion strategies.

Hypertension is a significant global health problem, especially in specific groups such as pregnant women. The high incidence and potential for serious complications demand non pharmacological management efforts and innovative use of local foods. This study examines the potential of local functional foods such as Ambon bananas, banana blossoms, and bamboo shoots as alternatives for health management and product development, particularly those related to hypertension in pregnant women. The method used was a systematic literature review using the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) approach, which encompasses four main stages: identification, screening, feasibility assessment, and analysis of results.The study results showed that the Ambon banana diet significantly reduced systolic and diastolic blood pressure. Factors such as age, family support, stress levels, and fast food consumption were shown to be significantly associated with the incidence of hypertension in pregnant women. Furthermore, bamboo shoot consumption significantly reduced blood cholesterol levels and blood pressure. In terms of product innovation, the fish floss formulation combined with banana blossoms or bamboo shoots received positive feedback from the panelists. The fermentation process of bamboo shoots is known to produce flour with a very high crude fiber content. Therefore, this local food has significant potential as a source of additional fiber and a raw material for value-added processed products to support food security and improve public health.

Cupping therapy is a traditional therapeutic method that has long been recognized in Thibbun Nabawi and continues to be used as a complementary therapy in contemporary healthcare. Along with the development of scientific research, cupping therapy has increasingly been examined from a medical perspective, highlighting the need for an integrative review that combines medical evidence and Islamic perspectives. This study aims to examine cupping therapy from both medical and Islamic perspectives based on a literature review. This study employed a qualitative approach using a literature review design. Data were collected from national and international scientific articles published between 2019 and 2025 through indexed databases, including Scopus, PubMed, Google Scholar, and Garuda. The review was complemented by Islamic sources such as the Qur’an, Hadith, and scholarly works on Thibbun Nabawi. Data were analyzed using descriptive qualitative analysis by categorizing findings into medical benefits and religious foundations of cupping therapy. The literature review indicates that cupping therapy has potential medical benefits, including pain reduction, blood pressure control, and improvement of metabolic parameters such as blood glucose and cholesterol levels. From an Islamic perspective, cupping therapy is regarded as part of Thibbun Nabawi and is recommended as a form of human effort to maintain health, while ultimate healing is believed to come from Allah SWT. Cupping therapy demonstrates strong relevance from both medical and religious perspectives. Integrating cupping therapy with modern medical principles and Islamic values may provide a holistic health approach that supports promotive, preventive, and curative healthcare services within complementary medicine.

Hypertension and hypercholesterolemia are closely related non-communicable diseases and major risk factors for cardiovascular disease, particularly in older adults. These conditions are influenced by medical, behavioral, family, and environmental factors, requiring a holistic family medicine approach through home visits. This study aimed to describe the clinical condition, family function, and environmental factors of a 60-year-old female patient with hypertension and hypercholesterolemia using the APGAR and SCREEM approaches. This study employed a qualitative descriptive design in the form of a case report involving Mrs. S (60 years old) in Lebbek Village, Pamekasan Regency. Data were collected through anamnesis, physical examination, total cholesterol measurement using a GCU meter, environmental observation, and assessment of family function and environmental factors. The results showed blood pressure values of 161/96 mmHg and 160/96 mmHg on repeated measurement, with a total cholesterol level of 154 mg/dL. The patient had a high-salt and high-fat diet with low physical activity. APGAR assessment indicated poor family function with a total score of 4, particularly in the partnership and resolve domains, while the growth domain was categorized as accepting. SCREEM analysis identified education as the main barrier. In conclusion, management of this condition requires family-based interventions focusing on improving family cooperation and health education tailored to the patient’s literacy level.

Cardiovascular diseases are the leading cause of death worldwide, accounting for 17.9 million deaths annually. Stroke and heart attacks often go undetected due to their silent nature. This community service activity aimed to increase community knowledge about stroke and heart attacks and conduct early detection through health screening. The activity was conducted in Lalimbue Village, Kapoiala District, Konawe Regency on May 11 and 18, 2025. Methods included healthy exercise, educational talk show, first aid workshop, and health screening (blood pressure, blood glucose, cholesterol). Knowledge evaluation used pre-test and post-test with 10 questions. Results showed 56 participants on implementation day and 17 on follow-up. Pre-test showed 23% had good knowledge, 34% moderate, and 43% poor. Post-test showed 87% good knowledge and 13% moderate. Health screening found 10.7% with hypertension and 10.7% with diabetes mellitus on implementation day. Follow-up found 47.1% with hypertension and 23.5% with diabetes mellitus. This study concluded that health education is effective in increasing community knowledge about stroke and heart attack prevention, and health screening is important for early detection of cardiovascular and metabolic diseases.

Diabetes mellitus and hypertension can be prevented through the consistent adoption of a healthy lifestyle. Women participating in religious study groups are an important segment of the community, as they play a significant role in shaping family lifestyles. A total of 30 Muslim women from the Perwiritan Muslimat Al-Jamiatul Amaliyah in Kampung Lalang, Sunggal, Deli Serdang, participated in the community service activities consisting of education and training on the prevention and management of diabetes mellitus and hypertension. The activities began with socialization of the community service program, followed by preparation by the team, including the development of educational materials and the design of pre- and post-test instruments. Based on the Wilcoxon test, the educational intervention was found to have a significant effect. This was reflected in an increase in participants’ knowledge regarding diabetes mellitus and hypertension after the intervention. Among the 30 participants, 43.3%  were classified as pre-hypertensive, 40% had stage 1 hypertension, 10% experienced a hypertensive crisis, 3.3% had stage 2 hypertension, and only one participant had normal blood pressure. Of the 30 women whose fasting blood glucose levels were measured, 43.3% were classified as pre-diabetic, 23.3% had diabetes mellitus, and 33.3% had normal glucose levels. The participants expressed their hope that future activities would include cholesterol level examinations.

The increasing prevalence of metabolic syndrome and chronic kidney disease underscores the need for simple, low-cost, and community-applicable screening indicators. This study aimed to evaluate the association between basic anthropometric parameters and blood pressure, metabolic indicators, and renal function among adults in the Badui Luar community. A cross-sectional design was employed involving 41 participants who underwent anthropometric assessment, biochemical measurements, and blood pressure evaluation. Pearson correlation analysis was used to examine linear associations between variables. The results demonstrated that neck circumference exhibited significant correlations with dyslipidemia components, including LDL (r = 0.377), TC/HDL ratio (r = 0.516), and HDL (r = –0.433), indicating cervical adiposity as a strong marker of atherogenic risk. Calf circumference showed protective correlations with fasting glucose (r = –0.352) and eGFR (r = 0.322), suggesting the metabolic relevance of peripheral muscle mass in glycemic regulation and renal status. Body mass index showed a weak correlation with systolic blood pressure (r = 0.149), whereas waist and hip circumferences exhibited mild, clinically insignificant correlations with triglycerides and total cholesterol. Overall, these findings highlight that simple anthropometric measures—particularly neck and calf circumference—may serve as early indicators of cardiometabolic and renal risk in community-based screening. Further longitudinal studies with larger and more heterogeneous populations are required to validate these associations and determine the predictive power of anthropometric indicators.

Non-communicable diseases (NCDs) are the leading causes of morbidity and mortality, particularly among older adults. Integrated Development Posts for Non-Communicable Diseases (Pos Pembinaan Terpadu Penyakit Tidak Menular / Posbindu PTM) play a crucial role in the early detection of NCD risk factors at the community level. This activity aimed to conduct NCD risk factor screening through the measurement of blood pressure, random blood glucose, total cholesterol, and uric acid levels, as well as to provide health consultations for participants of Posbindu Rosella, South Kembangan. The activity was conducted in November 2025 using a descriptive design. A total of 30 Posbindu participants were involved. Health examinations included blood pressure, random blood glucose, total cholesterol, and uric acid measurements. Data were analyzed descriptively and classified into normal and abnormal categories based on clinical guidelines. The majority of participants were female (80%), with a mean age of 60.5 ± 9.7 years. The mean systolic blood pressure was within the hypertensive range. Approximately 50% of participants had impaired glucose regulation, 60% experienced hyperuricemia, and 40% had total cholesterol levels classified as borderline or higher.  Health screening activities at Posbindu revealed a high prevalence of NCD risk factors among participants. Posbindu plays an essential role in early detection and community-based prevention of non-communicable diseases.

Hypertension is a major global health risk that requires accurate early detection, yet conventional methods struggle with complex and imbalanced health datasets. This study aims to optimize hypertension prediction using a Logistic Regression model integrated with Borderline-SMOTE to enhance recall and provide model transparency through SHAP (Shapley Additive Explanations). The method utilizes the BRFSS dataset, applying Borderline-SMOTE to address class imbalance at the decision boundary and XAI techniques for global and local interpretation. The findings show that the model achieved an accuracy of 0.719, an AUC of 0.800, and a significantly improved recall of 0.756. SHAP analysis identified age, high cholesterol, and BMI as the most influential risk factors, while waterfall plots successfully clarified individual risk extremes, ranging from 1.72% to 99.43% probability. These results imply that the proposed approach provides a sensitive and transparent screening tool for public health practitioners, effectively balancing statistical efficiency with clinical accountability.

The puring plant (Codiaeum variegatum), which has been known as an ornamental plant, apparently has significant therapeutic potential, supported by the presence of secondary metabolites such as flavonoids, tannins, saponins and alkaloids. Various modern studies report the biological activity of croton leaves, including anti-cholesterol, anti-hyperglycemia, antibacterial effects, and their use in biosurfactant formulations. However, studies on how varying extract concentrations influence bioactivity parameters quantitatively are still limited, especially in the context of dose-response relationships involving many biological parameters in one series of research. Therefore, this research was conducted to evaluate eight bioactivity parameters, namely PSM, SSSP, DSSP, SL, RO, SM, PSL, and ANA at croton leaf extract concentrations of 1%, 2%, and 4%. This research uses a laboratory experimental approach by extracting croton leaves through a maceration method using ethanol, then formulated in three concentration levels. Each parameter was analyzed quantitatively to observe the pattern of changes in biological response to variations in the dose administered. The results showed that most of the PSM, SSSP, DSSP, SL, and PSL parameters showed an optimum response at a concentration of 2%, which indicates that there is a most effective dose point before a decrease in activity occurs at the highest concentration. In contrast, several parameters such as RO, SM, and ANA showed a more fluctuating response, even the ANA parameter gave the highest value at a concentration of 4%, indicating that certain activities require higher compound levels to be achieved. In general, the response pattern found was not linear, but instead formed an optimum curve typical of the bioactivity of plant extracts. These findings confirm that determining dosage is very important in the use of croton leaf extract, both for pharmacological purposes and for the formulation of natural ingredient-based products.

Non-communicable diseases (NCDs) such as hypercholesterolemia, hyperuricemia, and hyperglycemia are common health problems among adults and can develop into cardiovascular diseases and diabetes if not detected early. This community service activity was carried out to provide education on risk factors, prevention, and control of cholesterol, uric acid, and blood glucose levels among parents of students at RA Avicenna in Sorong City, as well as to conduct examinations of these three parameters as an early detection effort. The methods used included interactive counseling using presentation media, question-and-answer discussions, and health checks using point-of-care testing (POCT) devices. A total of 23 respondents participated, ranging in age from 22 to 55 years. The results showed that 22 individuals had normal blood glucose levels and 1 individual had high glucose levels. Nine people had normal cholesterol levels, eight were in the borderline category, and six had high cholesterol levels. Five participants had normal uric acid levels, while 18 had elevated uric acid levels, for which additional education and recommendations for further medical examination were provided. In conclusion, educational activities combined with health screening proved effective in increasing community awareness and motivation to prevent NCDs early.

Background: Central Sulawesi has experienced a high frequency of natural disasters, with 111 recorded incidents in 2023 and 238 in 2022. The province was also designated as a high-risk disaster area in 2021. Blood pressure and cholesterol screenings are essential tools for diagnosing diseases, identifying risk factors, tracking disease progression, and assessing the effectiveness of treatments. Objective: This initiative aimed to provide free health screenings and offer basic food assistance to the community. Methods: The screenings were conducted in Wombo Village, Tanantovea District, Donggala Regency, Central Sulawesi. Results: The community health screenings revealed that the majority of adults and elderly participants had normal blood pressure and cholesterol levels. However, 5 individuals were found to have high blood pressure, while 20 participants exhibited normal levels. Additionally, 25 individuals had normal cholesterol levels. Conclusion: The screening results indicated that while most participants were in good health, a small percentage had elevated blood pressure, which warrants further attention. This initiative successfully provided free healthcare services and essential food support to the community.

Background: Central Sulawesi has experienced a high frequency of natural disasters, with 111 recorded incidents in 2023 and 238 in 2022. The province was also designated as a high-risk disaster area in 2021. Blood pressure and cholesterol screenings are essential tools for diagnosing diseases, identifying risk factors, tracking disease progression, and assessing the effectiveness of treatments. Objective: This initiative aimed to provide free health screenings and offer basic food assistance to the community. Methods: The screenings were conducted in Wombo Village, Tanantovea District, Donggala Regency, Central Sulawesi. Results: The community health screenings revealed that the majority of adults and elderly participants had normal blood pressure and cholesterol levels. However, 5 individuals were found to have high blood pressure, while 20 participants exhibited normal levels. Additionally, 25 individuals had normal cholesterol levels. Conclusion: The screening results indicated that while most participants were in good health, a small percentage had elevated blood pressure, which warrants further attention. This initiative successfully provided free healthcare services and essential food support to the community.

Total cholesterol measurement is essential for assessing cardiovascular risk, but consistency between laboratory instruments must be validated for reliable results. Architect C4000 and Alinity C1000 operate on enzymatic principles but differ in system design, reagents, and supporting technology. This study aimed to compare total cholesterol measurements between the two instruments using a non-parametric statistical approach (Mann-Whitney test). A comparative analytical design was conducted with 100 serum samples obtained via purposive sampling and divided for measurement with each device. Statistical analysis evaluated differences, and mean differences were calculated using the Hodges-Lehman method. Results showed mean cholesterol values of 182.98 mg/dL for Architect and 182.37 mg/dL for Alinity, with no significant difference (p=0.9942) and a median difference of 0.0 (95% CI: -9.0 to 9.0). Data distribution was nearly identical for both instruments in terms of mean and spread. Therefore, both methods demonstrate comparable validity in total cholesterol measurement, as they rely on similar principles and technologies, with reagents calibrated to the same standards.

Errors in the pre-analytical phase are a dominant factor causing inaccurate laboratory test results, including blood serum cholesterol analysis. Pre-examination specimen handling is crucial to ensure the quality of measurement results. This study aimed to compare serum cholesterol levels in blood frozen before centrifugation with those immediately centrifuged. The research method was analytical using a cross-sectional design. A total of 35 respondents were involved, consisting of laboratory staff, emergency room staff, pharmacists, and administration at Sinar Kasih GKST Tentena Hospital. Blood samples were obtained via venipuncture after participants had fasted for 10–12 hours. Each sample was then separated into two groups: those immediately centrifuged and those frozen 20–30 minutes before centrifugation. Data collection was carried out by examining serum cholesterol levels using an Erba Mannheim Chem-7 photometer. The results showed that the average cholesterol level in frozen samples was higher (161.4 mg/dL) compared to samples immediately centrifuged (140.45 mg/dL). The Mann-Whitney statistical test yielded a p-value of 0.006 (p<0.05), indicating a significant difference between the two treatments. This confirms that pre-analytical handling of blood specimens significantly impacts the validity of cholesterol test results. Therefore, careful attention to the pre-analytical stage is essential to ensure the accuracy of laboratory results.

Tempoyak is a traditional fermented paste made from durian in Indonesia, favored by the Malay ethnic group. While tempoyak holds a unique and significant place in Indonesia's rich culinary diversity, there is a notable gap in research about it compared to other fermented foods such as kimchi. More investigation is essential to grasp the microbial composition, interactions, and possible health advantages of tempoyak, which may offer benefits like boosting the immune system, reducing cholesterol levels, exhibiting probiotic qualities, preservation, and possessing antibacterial effects. Researchers could also discover vital insights regarding the history, cultural significance, production methods, microbiological issues, nutritional aspects, and future prospects of local foods like tempoyak. This research intends to examine and study tempoyak as a traditional fermented food through comprehensive literature review and data from earlier investigations. Tempoyak has a strong connection to Malay cultural identity, regardless of its production location. As a key element of the daily practices of the Malay people in Indonesia, tempoyak is typically featured at cultural events, weddings, or large gatherings. This cultural importance sets Indonesian tempoyak apart from its Malaysian counterpart. The process of making tempoyak involves mashing the durian flesh, mixing in salt, and letting the combined mixture ferment in a sealed container at room temperature for 4 to 7 days. The microbial population in tempoyak can differ but mainly includes Lactobacillus species, particularly Lactobacillus plantarum. Proximate analysis is an effective approach to evaluate the nutritional makeup of tempoyak. Differences in nutrient levels may arise from the various types of durian, salt elements, sterilization periods, temperatures, and length of fermentation. Potential research opportunities could explore tempoyak’s role in fostering sustainable food practices, additional health benefits from its consumption, and the development of innovative products based on tempoyak. The aim of this study will enhance the field and aid in safeguarding and promoting the culinary heritage of the Malay community.