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Esophageal atresia with tracheoesophageal fistula is a congenital anomaly requiring early diagnosis and prompt surgical correction. Gross type D esophageal atresia, characterized by both proximal and distal tracheoesophageal fistulas, is an exceedingly rare variant that poses significant diagnostic and operative challenges. We report a case of a full-term female neonate with a birth weight of 3,200 grams who presented with hypersalivation since the first day of life, accompanied by coughing and choking during feeding. Orogastric tube insertion failed, with the tube arrested at approximately 15 cm. The patient was referred with a diagnosis of neonatal pneumonia and suspected esophageal atresia with tracheoesophageal fistula. Physical examination revealed tachypnea, chest wall retraction, and respiratory distress requiring ventilatory support. Babygram demonstrated the orogastric tube tip arrested at the proximal esophageal pouch with distal gastrointestinal air. Contrast esophagography confirmed proximal esophageal atresia at the upper thoracic level with suspected proximal fistula. Associated findings included bilateral pneumonia, right upper lobe atelectasis, and vertebral anomalies suggestive of VACTERL association. Intraoperative findings confirmed Gross type D esophageal atresia with proximal and distal tracheoesophageal fistulas. Both fistulas were excised, followed by primary esophageal anastomosis and transanastomotic nasogastric tube placement. Gross type D esophageal atresia is a rare congenital anomaly that should be considered in neonates presenting with hypersalivation, failed orogastric tube insertion, and respiratory distress. Anatomical subtype confirmation relies on intraoperative findings. Early surgical repair can be performed successfully; however, associated anomalies necessitate careful long-term follow-up.

Preeclampsia is one of the leading causes of maternal mortality and may result in various complications during pregnancy and childbirth. In Tegal Regency, preeclampsia contributed to 27% of maternal deaths in 2024; therefore, studies on childbirth characteristics among mothers with this condition are needed. This study aimed to identify the characteristics of childbirth events in mothers with preeclampsia at Dr. Soeselo Slawi Regional Hospital, Tegal Regency. A descriptive design with a retrospective approach was used by reviewing the medical records of 202 mothers who delivered with preeclampsia during 2025. Data were analyzed univariately and presented as frequency distributions and percentages. The results showed that most mothers underwent operative delivery (62.38%), while spontaneous and induced labor accounted for 37.13% and 0.50%, respectively. Most deliveries occurred at preterm gestational age (62.38%), followed by term (36.14%) and postterm (1.49%) deliveries. Maternal and obstetric complications included bleeding (6.93%), fetal distress (4.95%), eclampsia (1.49%), and HELLP syndrome (0.99%). Most neonates had normal birth weight (82.18%) and did not require NICU care (95.05%), although low birth weight (17.82%) and NICU admission (4.95%) were still identified. The maternal clinical condition was dominated by blood pressure of 140–159/90–109 mmHg (75.74%). Proteinuria was found in 46.53% of respondents, with moderate proteinuria (+2) as the predominant category (38.30%). In conclusion, childbirth among mothers with preeclampsia was dominated by operative and preterm deliveries. These findings emphasize the importance of early detection and optimal management of preeclampsia to reduce maternal and neonatal complications and improve the quality of maternal-infant health services overall.

Low Birth Weight (LBW) refers to infants born with a birth weight of less than 2,500 grams and remains an important issue in neonatal health due to its association with increased neonatal morbidity and mortality. To analyze the determinants of LBW based on primary studies published from 2021 to 2026. A literature review was conducted using the PRISMA approach. Article searches were performed through PubMed, Google Scholar, Scopus, ScienceDirect, and ProQuest using the keywords low birth weight, determinant factors, risk factors, BBLR, and faktor risiko with Boolean operators AND/OR. The inclusion criteria were primary studies, full-text availability, publication in Indonesian or English, and publication years from 2021 to 2026. A total of 20 articles were included, consisting of 15 international articles and 5 national sources. The review showed that LBW is influenced by interrelated maternal, nutritional, obstetric, and sociodemographic factors during pregnancy. The most dominant factors included multiple pregnancy with an adjusted OR of 21.74, maternal food insecurity with an AOR of 6.85, maternal hemoglobin level <11 g/dL with an AOR of 5.21, lack of iron-folic acid supplementation with an AOR of 4.17, maternal age ≤20 years with an AOR of 3.42, pregnancy interval <1 year with an adjusted OR of 2.92, missed antenatal care visits with an AOR of 2.74, smoking during pregnancy with an OR of 2.18, and maternal hypertension with an AOR of 1.94. LBW is influenced by multiple interrelated factors; therefore, efforts to reduce its incidence should focus on evidence-based interventions, particularly through optimizing antenatal care services, improving maternal nutritional status, and early detection of pregnancy.

Stunting remains a significant nutritional issue because it can impact a child's long-term growth and development. A history of low birth weight (LBW) is suspected to play a role, reflecting the condition of fetal growth during pregnancy. This study aimed to determine the relationship between a history of LBW and the incidence of stunting in children aged 2–5 years at the Bandarharjo Community Health Center in Semarang in 2025. This study used an analytical design with a case-control approach. The study sample consisted of 203 toddlers selected using consecutive sampling. Data were obtained from the KIA book and height measurements based on WHO standards. Analysis was performed using the Chi-Square test and Odds Ratio (OR) calculation. The proportion of LBW was 10.8% and stunting was 31.0%. There was a significant relationship between a history of LBW and the incidence of stunting (p = 0.012). Toddlers with a history of LBW had approximately a threefold greater risk of experiencing stunting compared to toddlers born with normal weight (OR = 3.059). There is a relationship between a history of low LBW and the incidence of stunting in toddlers aged 2-5 years at the Bandarharjo Community Health Center, Semarang in 2025.

Neonatal sepsis is a major factor contributing to morbidity and mortality in newborns. C-Reactive Protein (CRP) and leukocytes are laboratory tests used as indicators of inflammation. This study aims to determine the relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients. The research method used was an observational analytic with a cross-sectional approach. Neonatal sepsis at PKU Muhammadiyah Yogyakarta in the period 2021-2026 consisted of 30 samples using a total sampling technique. The distribution of respondents was dominated by male gender compared to female gender, who had a low birth weight <2,500 grams. Based on the study, normal CRP levels were found in 21 respondents, which was caused by a delay in increasing CRP levels. Leukocytes had high levels in 18 respondents. Leukocytes are an initial phase of examination in detecting inflammation that does not require a long time, have several different morphological types in detecting inflammation in the body. This study shows that the most dominant increase in leukocyte levels is found in eosinophils and neutrophils. Based on medical record data at PKU Muhammadiyah Hospital Yogyakarta, analysis using the Spearman correlation test yielded a correlation coefficient of 0.261 with a significance value of 0.164 (p > 0.05). The results showed no significant relationship between the studied variables, with a positive direction and weak correlation strength. The conclusion of this study is that there is no significant relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients.

Neonatal sepsis is a major factor contributing to morbidity and mortality in newborns. C-Reactive Protein (CRP) and leukocytes are laboratory tests used as indicators of inflammation. This study aims to determine the relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients. The research method used was an observational analytic with a cross-sectional approach. Neonatal sepsis at PKU Muhammadiyah Yogyakarta in the period 2021-2026 consisted of 30 samples using a total sampling technique. The distribution of respondents was dominated by male gender compared to female gender, who had a low birth weight <2,500 grams. Based on the study, normal CRP levels were found in 21 respondents, which was caused by a delay in increasing CRP levels. Leukocytes had high levels in 18 respondents. Leukocytes are an initial phase of examination in detecting inflammation that does not require a long time, have several different morphological types in detecting inflammation in the body. This study shows that the most dominant increase in leukocyte levels is found in eosinophils and neutrophils. Based on medical record data at PKU Muhammadiyah Hospital Yogyakarta, analysis using the Spearman correlation test yielded a correlation coefficient of 0.261 with a significance value of 0.164 (p > 0.05). The results showed no significant relationship between the studied variables, with a positive direction and weak correlation strength. The conclusion of this study is that there is no significant relationship between C-Reactive Protein levels and leukocyte profiles in neonatal sepsis patients.

Low Birth Weight (LBW) infants are a group of neonates who are highly susceptible to thermoregulation disorders, particularly hypothermia, due to limited subcutaneous fat reserves, a relatively large body surface area, and the immaturity of the temperature regulation system. Untreated hypothermia can lead to serious complications such as hypoxia, sepsis, hypoglycemia, apnea, and failure to gain weight, which ultimately contribute to increased neonatal morbidity and mortality. One of the non-pharmacological nursing interventions that can be used to prevent hypothermia is nesting care, a positioning technique using supportive materials to create a comfortable environment that resembles the intrauterine position.This study aimed to determine the effectiveness of nesting care in LBW infants as an  effort to increase body temperature in infants experiencing hypothermia. The method used was a descriptive case study with a nursing process approach involving three participants. The intervention consisted of nesting care administered for three days, with a duration of 30 minutes once daily using the quarter-prone or semi-prone position. The results showed that after the nesting intervention, two out of three participants experienced an increase in body temperature approaching normal values on the third day. Improvement in the infants' condition was also indicated by reduced crying and longer periods of calm sleep compared to the condition before the intervention. Body temperature measurements and observations of the infants’ condition were conducted periodically to evaluate the effectiveness of the intervention, with an average temperature increase of approximately 0.2°C at the end of the intervention. In conclusion, nesting care can be used as an effective non-pharmacological nursing intervention to help increase body temperature in LBW infants experiencing hypothermia.

Teenage pregnancy remains a reproductive health issue in Indonesia, including in Batam City. According to data from the Batam City Health Office in 2024, there were 18 cases of teenage pregnancy (0.06%) with the Lubuk Baja Health Center being one of the highest areas. Pregnant teenagers are at high risk of complications such as anemia, malnutrition, and low birth weight (LBW), which contribute to high rates of maternal and infant morbidity. This study used a descriptive method with a case study approach on Ny. S, an 18-year-old teenager with a pregnancy in the Lubuk Baja Health Center area of Batam City in 2025. Data collection was conducted through interviews, observations, physical examinations, and SOAP documentation following the 7-step Varney obstetric management. The findings revealed that Ny. S experienced mild complaints such as nausea, reduced appetite, and anxiety about her pregnancy. After three visits, the mother's complaints decreased, appetite improved, anxiety decreased, and nutritional status was within normal limits. Comprehensive midwifery care with a biopsychosocial approach was proven effective in improving both the physical and mental health of pregnant teenagers and preventing pregnancy complications.

Data from the 2020 LFSP (Long Form Population Census) recorded a maternal mortality ratio of 189 per 100,000 live births, while the infant mortality rate was recorded at 16.85 per 1,000 live births. The causes of maternal mortality were hemorrhage, preeclampsia/eclampsia, infection, prolonged labor, and miscarriage. Meanwhile, the majority of infant deaths were due to low birth weight, asphyxia, and infection at birth. Stunting remains a particular concern in Tegal City. Various measures have been taken, and the stunting rate has decreased to around 13.8% according to data from early 2025. This PKM is expected to increase public knowledge on caring for pregnant women, women in labor, postpartum women, and newborns, as well as preventing stunting in children, thereby reducing maternal and infant mortality rates. The methods used in this activity include health education and outreach with a promotive and preventive approach, targeting pregnant women and mothers with infants and toddlers. Community service was held on Wednesday, December 17, 2025, from 8:30 a.m. to 12:00 p.m. at the Boegenvil Health Center in Cabawan Village, Tegal City, with 53 participants. The results of this activity showed an increase in the level of knowledge of the participants, from 11 people with a good level of knowledge to 41 people after receiving counseling, with 3 participants still having a low level of knowledge.

Data from the 2020 LFSP (Long Form Population Census) recorded a maternal mortality ratio of 189 per 100,000 live births, while the infant mortality rate was recorded at 16.85 per 1,000 live births. The causes of maternal mortality were hemorrhage, preeclampsia/eclampsia, infection, prolonged labor, and miscarriage. Meanwhile, the majority of infant deaths were due to low birth weight, asphyxia, and infection at birth. Stunting remains a particular concern in Tegal City. Various measures have been taken, and the stunting rate has decreased to around 13.8% according to data from early 2025. This PKM is expected to increase public knowledge on caring for pregnant women, women in labor, postpartum women, and newborns, as well as preventing stunting in children, thereby reducing maternal and infant mortality rates. The methods used in this activity include health education and outreach with a promotive and preventive approach, targeting pregnant women and mothers with infants and toddlers. Community service was held on Wednesday, December 17, 2025, from 8:30 a.m. to 12:00 p.m. at the Boegenvil Health Center in Cabawan Village, Tegal City, with 53 participants. The results of this activity showed an increase in the level of knowledge of the participants, from 11 people with a good level of knowledge to 41 people after receiving counseling, with 3 participants still having a low level of knowledge.

The goal of continuous midwifery care is to use the SOAP documentation technique to provide comprehensive care to pregnant women up to birth control according to care standards. From May 2 - July 14, 2025, Mrs.C, G2P1A0, 32 years old received continuous midwifery care from pregnancy until get contraception methods, starting at 34 weeks of gestation. The mother complained of back pain during prenatal check-ups. The labor process went smoothly. With the assistance of a midwife, the baby was born on June 10, 2025. Birth weight: 3000 grams; length: 50 cm; head circumference: 34 cm; chest circumference: 33 cm; received Hb0 vaccine two hours after birth, eye ointment, and vitamin K shortly thereafter. The baby did not experience any problems or complaints during the first visit. Mrs. C received four visits during the postpartum period. The mother did not feel anything during the first visit up to the following visits. She continued to breastfeed exclusively, and her vital signs and fundal height returned to normal. The mother used a three-month injectable contraceptive so as not to interfere with the exclusive breastfeeding program. Mrs.C has received continuous midwifery care during pregnancy and contraceptive use, and her health is normal. It is expected that the midwife will be able to provide continuous midwifery care so that in the event of an emergency, it can be immediately identified and promptly handled.

A high-risk pregnancy is a pregnancy that can affect both the pregnancy, delivery, newborn, and postpartum period. There are several high-risk pregnancies, including pregnant women who are <145cm tall, have low birth weight, are too young, and give birth too closely spaced, or what is known as the 4T. Prevention is carried out by conducting comprehensive supervision, this is a way to reduce MMR and IMR. The Central Java government has developed the One Student One Client (OSOC) program, it is hoped that the implementation of this program can reduce MMR in Central Java. MMR according to WHO in 2023 reached 189/100,000 live births, MMR based on ASEAN reached 235/100,000 live births, MMR according to the Indonesian Ministry of Health reached 205/100,000 live births, MMR in Central Java in 2023 has reached 485/100,000 live births, MMR in Brebes in 2023 54/100,000 live births and at the Bantarkawung Community Health Center MMR in 2023 amounted to 2 cases of maternal death. In this study, researchers used Varney and SOAP to document midwifery care comprehensively, with direct qualitative descriptive approach methods such as observation, interviews, and documentation.

ABSTRACT Background: Low birth weight babies are the age group that has the highest risk of health problems, so low birth weight babies need optimal care. Kangaroo method care is one of the interventions to increase weight in lowbirth weight babies. Objective: The purpose of this study is to examine the difference in the weight of low birth weight babies before and after being given kangaroo care. Method: The research design used was preexperimental pretest posttest without control group on 16 respondents from 50 pupulation with tehnique sampling purposive sampling. Normality test using the Shapiro Wilk test obtained normally distributed data. Result: The results of the study showed that the average weight of lowbirth weight babies before kangaroo care was 1843.12 grams and the average weight of lowbirth weight babies after kangaroo care was 1995 grams. The results of data analysis using the paired t test with a significance of p < 0.05 found p = 0.000, which means that there is a significant difference between the weight of lowbirth weight babies before and after being given kangaroo care. Conclusion: Providing kangaroo care can increase the weight of LBW babies.

Low Birth Weight (LBW) remains a critical global health issue that significantly contributes to neonatal morbidity and mortality, particularly in developing countries such as Indonesia. The main challenge in addressing LBW lies in its complex and multifactorial risk profile, which involves biological, social, environmental, and healthcare-related determinants. This study aims to analyze and synthesize the risk factors associated with LBW based on recent scientific literature. A literature review method was applied by searching articles from Portal Garuda, DOAJ, PubMed, and Google Scholar published between 2020 and 2025 using relevant keywords. The findings indicate that maternal age, interpregnancy interval, nutritional status, anemia, preeclampsia, infections, socioeconomic conditions, environmental exposure, and the quality of antenatal care are significant determinants of LBW. The synthesis of evidence confirms that LBW is influenced by the interaction of multiple individual and healthcare system factors rather than a single cause. In conclusion, this study highlights the urgent need to strengthen antenatal care services, improve maternal nutritional status, control maternal diseases during pregnancy, and implement community-based promotive and preventive strategies as key efforts to reduce the incidence of LBW.

This study aims to model the Infant Mortality Rate (IMR) in East Nusa Tenggara Province using truncated spline nonparametric regression. In this study, IMR is associated with four predictor variables: the percentage of poor people, the percentage of pregnant women under 19 years of age, low birth weight, and life expectancy. These four variables have an unpatterned relationship, indicating the presence of a nonparametric component in the model. The truncated spline regression method was chosen because of its ability to handle nonlinear relationships between variables. The results showed that the best model was obtained using three knot points, which produced a coefficient of determination (R²) of 97.47%. This indicates that the truncated spline regression model is able to explain 97.47% of the variation in IMR in East Nusa Tenggara Province. In addition, the four predictor variables have a significant influence on the model, making a significant contribution in explaining the factors that influence IMR in the region.

Anemia in pregnant women is a health problem that contributes significantly to Low Birth Weight (BBLR), a serious issue in Indonesia with a prevalence exceeding 15% according to WHO, and is a major contributor to the high Neonatal Mortality Rate. This study aims to examine the relationship between anemia in pregnant women and the incidence of BBLR at the Sungai Durian Health Center, Sintang Regency. Using a case control analytical research design with secondary data from medical records in 2024, the sample used was 116 respondents, consisting of 58 pregnant women with BBLR babies as the case group and 58 pregnant women with normal birth weight babies (BBLN) as the control group, which were taken by total sampling technique. Data analysis was carried out using the Chi-Square test and the Odds Ratio (OR) with a significance level of 95%. The results of the study show that the incidence rate of BBLR at the Sungai Durian Health Center in 2024 is 25.8%, and the incidence of anemia in pregnant women is 46.6%. Statistical tests showed a significant relationship between anemia in pregnant women and the incidence of BBLR (p < 0.05). Pregnant women with anemia had a 21.758 times greater risk of giving birth to a BBLR baby compared to non-anemic mothers (OR=21.758; CI 95% = 1.45–7.08). The study concluded that there was a relationship between the nutritional status of pregnant women and the incidence of preeclampsia at the Sungai Durian Sintang Health Center.

Low Birth Weight (LBW) is one of the leading causes of neonatal mortality and contributes to an increased risk of growth and developmental disorders in later life. Maternal nutritional status during pregnancy and the utilization of antenatal health services are important factors influencing fetal growth and development. Pregnant women with poor nutritional status are at higher risk of delivering low birth weight infants due to insufficient intake of essential nutrients required during pregnancy. In addition, inadequate utilization of antenatal care services may result in delayed detection and management of pregnancy-related complications. This study aimed to determine the relationship between maternal nutritional status and the utilization of health services with the incidence of LBW. The research employed an observational analytic design with a cross-sectional approach. The study population consisted of all women who delivered in the working area of Puskesmas X in 2026. A total of 80 respondents were selected using purposive sampling. Data were collected from maternal and child health (MCH) books and medical records and analyzed using the Chi-square test. The results showed a significant relationship between maternal nutritional status and the incidence of LBW (p=0.002), as well as between the utilization of health services and the incidence of LBW (p=0.004). It can be concluded that maternal nutritional status and compliance with antenatal visits are significantly associated with LBW, highlighting the need to improve nutritional monitoring and the quality of antenatal care services.

In Indonesia in 2020, there were 28,158 infant deaths, of which 20,266 (72%) occurred during the neonatal period. Among these neonatal deaths, 27.4% were caused by neonatal asphyxia. In West Kalimantan Province, there were 682 neonatal deaths recorded in 2023. The leading causes of neonatal mortality in 2023 were Low Birth Weight (LBW) and prematurity (32%), followed by asphyxia (24%). Based on the 2023 Sintang Regency health profile, the infant mortality rate was 9.6 per 1,000 live births. This study aimed to determine the relationship between LBW and the incidence of neonatal asphyxia. The research used an analytical observational approach with a cross-sectional design. The study was conducted at Ade M. Djoen Sintang Regional Hospital from January to December 2023 using secondary data. The population consisted of all newborns at Ade M. Djoen Sintang Regional Hospital, totaling 104 infants. A total sampling technique was applied, resulting in a sample size of 104 respondents. Data were analyzed using the Chi-square test. The Chi-square analysis produced a p-value of 0.0241 (p < 0.05), indicating a statistically significant relationship between Low Birth Weight (LBW) and neonatal asphyxia. The Odds Ratio (OR) of 4.021 shows that LBW infants have a 4.021-fold higher risk of experiencing neonatal asphyxia compared to infants with normal birth weight.  

Anemia during pregnancy is a significant maternal health issue with serious impacts on maternal and perinatal outcomes, including complications such as severe preeclampsia, postpartum hemorrhage, and low birth weight (LBW), all of which contribute to increased morbidity and mortality rates. This literature review aims to analyze the clinical impacts of pregnancy anemia, related complications, and effective management strategies based on the latest scientific evidence (2020-2024). The study examines the relationship between anemia and preeclampsia, LBW, and postpartum hemorrhage, as well as the importance of nutritional fulfillment in prevention and management. Five research articles from indexed journals were collected from the Scopus database, with inclusion criteria of studies with clear designs, focusing on pregnancy anemia, and published in Indonesian or English. The analysis results show that pregnancy anemia is a predisposing factor for preeclampsia through mechanisms such as placental hypoxia and oxidative stress. Anemia is also closely related to an increased incidence of LBW and postpartum hemorrhage, particularly due to lower hemoglobin reserves and uterine contractility issues. Adequate nutritional fulfillment is influenced by socioeconomic barriers, supplementation side effects, and lack of family support. Anemia management requires a comprehensive approach, including routine screening, prophylactic supplementation, nutritional education, and effective referral systems for complex cases. Prevention through early detection and timely intervention is crucial in reducing maternal and perinatal morbidity.

This paper applies the Gamma Regression Model to determine the probability of newborns in the Diyala Province developing neonatal jaundice, or hyperbilirubinemia. This disease is prevalent, and it may be severe due to the large amount of unconjugated bilirubin in the blood. The aim of the study was to test the relationship between the levels of bilirubin and a set of independent variables, including the weight of birth, gestational age, and the proportion of red blood cells (PVC). 67 worth of data regarding neonatal cases was collected, and the outcome was that the model fitted well. The findings further indicated that whereas the influence of PVC was significant and positive on the bilirubin level, lower gestational age and less weight at birth had significant negative influence. As the results of the study indicate, the Gamma Regression Model is an effective tool to assess medical data and predict critical scenarios, which assists a clinician with the timely and accurate decision-making.