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Background: Ischemic stroke is one of the leading causes of death and disability, especially in the elderly population. The impact of stroke is not only limited to physical activity, but also greatly affects the psychosocial condition of the sufferer. From a psychological aspect, stroke sufferers often experience various complex emotional disorders. Research tends to be deep sadness, anger, disappointment, and feelings of helplessness. One of the significant psychosocial problems experienced by stroke survivors is a decrease in low self-esteem. Methods: The approach used in this study is a qualitative approach. The data source in this study came from informants. This research was conducted at Royal Prima Hospital, Jambi City. Results: Based on the results of the research that has been conducted, it was found that stroke patients experience various psychological changes due to physical limitations that arise after having a stroke. Family support is the most influential factor in the psychological condition of stroke patients.  Families who always accompany patients are able to help patients accept sick conditions and increase patient morale during the rehabilitation process. However, the results of the study show that psychological support from nurses is still not fully optimal. Conclusion: Based on the results of the study, stroke patients experience psychological changes such as feeling embarrassed, insecure, feeling a burden on the family, withdrawing from the social environment, and losing their zest for life due to physical limitations. This condition shows that the stroke has an impact not only on the physical, but also on the psychological of the patient. Family support in the form of attention, motivation, affection, mentoring, and medical assistance is very helpful in increasing the patient's enthusiasm and confidence during rehabilitation. Nurses also play a role in the recovery process through health education, motivation, and treatment assistance. However, emotional support and therapeutic communication from nurses are still not optimal because services are more focused on medical measures.

Pneumonia caused by extensively drug-resistant (XDR) Pseudomonas aeruginosa is still  clinicaly chalenging, particularly among geriatric patients with neurological comorbidities such as stroke. This report presents a case of XDR P. aeruginosa pneumonia complicated by sepsis in a 73-year-old patient, characterized by persistent leukocytosis until the tenth day of hospitalization despite empirical meropenem therapy. This evidence-based case report aims to analyze clinical outcomes, specifically 28-day and 30-day mortality rates, and to identify mortality predictors in the adult population through a systematic literature search of the PubMed and Google Scholar databases for the 2019–2026 period. Synthesized evidence from six core studies indicates that XDR P. aeruginosa infections carry a profoundly high 28-day mortality rate, ranging from 41% to 51% in cohorts receiving antibiotic monotherapy. Key mortality predictors identified include the presence of sepsis or septic shock, a delay in initiating adequate therapy exceeding 52 hours, advanced age, and the requirement for Intensive Care Unit (ICU) admission. The phenomenon of persistent or worsening leukocytosis during treatment, as observed in this case, serves as a critical clinical indicator associated with antimicrobial response failure and a dismal prognosis. Ultimately, XDR P. aeruginosa pneumonia is associated with poor clinical outcomes, where therapeutic success is strictly contingent upon the timely administration of antibiotic regimens with proven activity against these highly resistant isolates.

Stroke is a leading cause of disability that requires long-term rehabilitation. Herbal-based therapies, such as Shengmai San, may complement conventional medical treatments in aiding post-stroke recovery. This quasi-experimental study involved 10 post-stroke patients who received Shengmai San therapy for four weeks, with one session per week. Key parameters measured included blood pressure, muscle strength, motor function, sensory complaints (e.g., tingling, numbness), sleep quality, and Traditional Chinese Medicine diagnostic findings (pulse and tongue). The results showed clinical improvements across all patients, including stabilized blood pressure, enhanced muscle strength and mobility, reduced sensory complaints, better sleep quality, and increased physical stamina. Pulse and tongue diagnostics suggested improved Qi and Xue circulation. No significant side effects were reported. The study concludes that Shengmai San is a promising adjunct therapy for post-stroke rehabilitation, especially for patients with Qi deficiency and impaired blood circulation. However, the study suggests that Shengmai San should not replace conventional treatments but be used as a complementary therapy to support recovery.

The problem that occurs in stroke patients is damage to the autonomic nervous system that regulates intestinal peristalsis, causing a decrease in the defecation reflex and leading to constipation. If constipation is not treated properly, it will affect the quality of life of stroke patients. Constipation can be treated pharmacologically and non-pharmacologically. One non-pharmacological treatment is abdominal massage. Abdominal massage can stimulate the parasympathetic nervous system, which can increase digestive system motility, reduce tension in the abdominal muscles, and have a relaxing effect on the sphincter. The design used in the preparation of the final scientific paper for the nursing study was a one-group pretest-posttest case study with abdominal massage intervention on three respondents who had experienced constipation for ≥ 72 hours. Abdominal massage was given once a day for 10-15 minutes for three consecutive days. The constipation scores using the Constipation Assessment Scale (CAS) were as follows: respondent 1, Mrs. L, from 13 to 6; Mrs. W, from 12 to 11; and Mrs. W, from 15 to 11. There was a decrease in the CAS score before and after the abdominal massage was administered, but it was not yet able to significantly alleviate constipation in stroke patients. The application of this EBP is expected to provide additional information on the administration of abdominal massage to stroke patients experiencing constipation for ≥72 hours.

Stroke is one of the non-communicable diseases that is the leading cause of disability and death in the world. Clinical factors such as hypertension, diabetes mellitus, body mass index (BMI), and unhealthy lifestyle are known to contribute to the incidence of stroke. Oe-Cusse Referral Hospital serves as the main referral center in the treatment of stroke cases, but data on contributing clinical factors and medical treatment and rehabilitation strategies are still limited. This study aims to analyze the clinical factors that contribute to the incidence of stroke and describe medical treatment and rehabilitation strategies in stroke patients at Oe-Cusse Referral Hospital.This study is a quantitative study with a cross-sectional observational design. The research sample amounted to 50 stroke patients who were treated in the January-November 2025 period, selected using purposive sampling techniques. Data were collected through medical records and questionnaires related to medical treatment and rehabilitation. Data analysis was carried out using the SPSS program, including descriptive analysis and logistic regression to see the relationship between clinical factors (hypertension, diabetes mellitus, lifestyle, BMI, and other factors) and stroke incidence. The results of the descriptive analysis showed that the average age of stroke patients was 56.2 ± 9.8 years, with an age range of 39–78 years. The average BMI of the patient was 27.5 ± 3.1 kg/m² which indicates a tendency to be overweight. The average systolic blood pressure of the patient was 150 ± 18 mmHg, indicating the predominance of hypertension in stroke patients. The average length of rehabilitation lasted 6.3 ± 1.8 weeks. Logistic regression analysis showed a significant relationship between clinical factors, especially hypertension, BMI, and diabetes mellitus, and stroke incidence. Clinical factors such as hypertension, high BMI, and diabetes mellitus contribute significantly to the incidence of stroke at Oe-Cusse Referral Hospital.

Hypertension in the elderly requires long-term treatment to prevent cardiovascular consequences. Adherence to antihypertensive medication is crucial for blood pressure management. Adherence to antihypertensive medication is a crucial aspect in hypertension management. Poor adherence can lead to uncontrolled blood pressure, thereby increasing the risk of cardiovascular problems, including stroke, myocardial infarction, and heart failure. This study aims to determine the correlation between adherence to antihypertensive medication and blood pressure in the elderly at the Ronggo Husada Primary Inpatient Clinic in Malang. This study used a cross-sectional design. The cohort consisted of 52 geriatric patients with hypertension who consistently visited the Ronggo Husada Primary Inpatient Clinic in Malang. The sample consisted of 40 patients. The sampling method used was purposive sampling. Research factors included medication adherence and blood pressure. Data collection was conducted through a questionnaire. This study was conducted at the Ronggo Husada Primary Inpatient Clinic in Malang on November 6, 2025. Data processing used the Chi-square test. The analysis included univariate and bivariate analyses, using the Chi-square test. The results showed that more than 50% of elderly participants demonstrated moderate adherence to antihypertensive medication (18 individuals (45%). Nearly 50% of elderly participants suffered from stage I hypertension (14 individuals (35%), and stage II hypertension (11 individuals (27.5%). Statistical analysis using the Chi-square test showed a significant correlation between adherence to antihypertensive medication and blood pressure in the elderly, with a p-value of 0.000, which is below the alpha threshold of 0.05 (5%). Elderly individuals who demonstrated strong adherence had better blood pressure regulation compared to those with poor adherence. These results emphasize the importance of adherence to therapy in the management of hypertension in the elderly.    

Hypertension is a primary risk factor for cardiovascular diseases, including stroke, coronary artery disease, atrial fibrillation, and peripheral vascular disease. Often referred to as "The Silent Killer," its onset is frequently asymptomatic, making early detection challenging. Effective interventions, both pharmacological and non-pharmacological, are necessary to manage hypertension and reduce complications. Long-term treatment requires adherence to prescribed medications, with self-care management playing a vital role in minimizing hypertension's adverse effects. Self-efficacy, or an individual's belief in their abilities, is crucial for improving medication adherence and self-care activities. This study aimed to examine the correlation between self-efficacy and self-care management in relation to medication adherence among hypertension patients at RSUD Mandau District. A non-experimental, quantitative, analytic correlation study with a cross-sectional design was conducted, involving 38 hypertension patients. Self-efficacy was measured using the MASES-R (Medication Adherence Self-Efficacy Scale-Revision), medication adherence was assessed with the MMAS-8 (8-item Morisky Medication Adherence Scale), and self-care management was evaluated using the HBP-SCP (Hypertension Self-Care Profile). The findings revealed a significant correlation between self-efficacy and medication adherence (p=0.000, r=0.594). Additionally, self-care management was significantly correlated with medication adherence (p=0.027, r=0.360). In conclusion, self-efficacy and self-care management both significantly correlate with medication adherence in hypertension patients at RSUD Mandau District.

Hypertension substantially increases the risk of developing secondary conditions, including stroke, renal disease, coronary heart disease, and heart failure. Early management is therefore essential to prevent complications and adverse outcomes. Evidence indicates that untreated hypertension contributes to approximately 60% of stroke cases. Public knowledge regarding hypertension-related complications remains limited, and many individuals are unable to identify early signs of stroke the most common complication associated with hypertension. This study aimed to assess the knowledge of hypertensive patients regarding stroke risk and management at Santa Elisabeth Hospital Medan in 2024. A descriptive research design was employed. The sample consisted of 67 hypertensive patients attending the outpatient clinic, selected through purposive sampling. Data were presented using frequency distribution tables. The findings revealed that 52.2% of respondents demonstrated poor knowledge, 32.8% had moderate knowledge, and only 14.9% showed good knowledge regarding stroke risk and management. These results underscore the need for patients to adopt healthier lifestyles and for the hospital to strengthen educational efforts by providing more engaging and interactive learning materials for patients and their families.

Hypertension is one of the most common non-communicable diseases, with a high incidence rate that has become a major global health concern. It is often referred to as a “silent killer” because many patients are unaware of their condition until serious complications arise. In Indonesia, the prevalence of hypertension is relatively high, yet many sufferers remain undiagnosed or do not receive proper medical treatment. Several risk factors contribute to hypertension, including age, heredity, high-salt diet, obesity, lack of physical activity, and unhealthy lifestyles such as smoking and alcohol consumption. Without proper management, hypertension may lead to severe complications such as stroke, heart failure, and chronic kidney disease. Management of hypertension generally involves pharmacological therapy, such as the administration of antihypertensive drugs, as well as non-pharmacological interventions through lifestyle modifications. Nurses play a crucial role in patient education, monitoring, and preventing complications through comprehensive nursing care. The purpose of this study is to describe the nursing care provided to Mr. R, who experienced a cardiovascular system disorder, namely hypertension, in the Dahlia Ward of RSUD dr. Soeselo, Tegal Regency. The research method used was descriptive with a case study approach, allowing for a systematic and clear presentation of the patient’s condition. The case findings showed that the patient’s main complaint was a headache radiating to the nape of the neck. Based on nursing assessment, two nursing diagnoses were identified: acute pain and lack of knowledge regarding the disease and its management. Interventions were determined using national standards such as SDKI, SLKI, and SIKI, which are expected to reduce symptoms and improve the patient’s understanding of hypertension.

Hypertension is a chronic condition with a high prevalence among the elderly population and is often overlooked despite its potential to cause severe complications, including cardiovascular disease, stroke, and kidney damage. Effective management of hypertension requires not only pharmacological treatment but also patient adherence to prescribed therapies, which is closely linked to their knowledge and understanding of the disease. This study aims to analyze the relationship between knowledge levels and medication adherence among elderly hypertension patients at Sari Asih Hospital in Tangerang. A quantitative approach with a cross-sectional design was employed, and a total of 80 respondents were selected using non-probability sampling techniques. Data were collected using structured questionnaires that assessed both knowledge about hypertension and adherence to medication regimens. Statistical analysis was conducted using Kendall’s tau correlation, which revealed a strong and significant relationship between knowledge and medication adherence (τ = 0.759, p = 0.000). These findings indicate that elderly patients with higher levels of knowledge about hypertension are more likely to adhere to their medication schedules consistently, thereby reducing the risk of complications. The results underscore the importance of continuous health education and counseling for elderly patients to strengthen their awareness and self-management skills. In conclusion, increasing knowledge through targeted health promotion programs can play a vital role in improving adherence to hypertension treatment and ultimately enhancing patient outcomes.

Hypertension is a chronic disease that requires long-term treatment. However, in reality, many patients remain non-adherent to their prescribed therapy. Non-adherence can lead to serious complications such as stroke, kidney failure, or heart disease. One of the crucial factors that can improve treatment adherence is family support. This support may include attention, supervision, motivation, and practical assistance such as reminding patients of their medication schedules. The aim of this study was to examine the relationship between family support and medication adherence among hypertensive patients at the Internal Medicine Specialist Polyclinic of RSSA Sangiang. This study employed a quantitative correlational design with a cross-sectional approach. A total of 189 respondents were recruited using consecutive sampling. The research instruments consisted of a family support questionnaire and the Morisky Medication Adherence Scale (MMAS-8) to assess adherence. Data were analyzed using the Spearman Rank test to determine the relationship between the two variables. The results showed that most respondents received family support at a moderate level (55.0%). Meanwhile, medication adherence among hypertensive patients was categorized as moderate in 49.2% of respondents. The Spearman test revealed a highly significant relationship between family support and medication adherence, with p=0.000 and a correlation coefficient r=0.832. In conclusion, family support plays a vital role in improving medication adherence among hypertensive patients. Therefore, healthcare providers are encouraged to involve families in the treatment process and provide continuous education to ensure adherence and prevent complications.

Hypertension, often referred to as high blood pressure, is a major global health problem that significantly increases the risk of atherosclerotic cardiovascular disease, heart failure, stroke, and kidney failure. Various complementary and alternative therapies have been explored to support conventional treatments in reducing blood pressure, one of which is smile therapy. This study aimed to analyze the effect of smile therapy on blood pressure among hypertensive patients at RSUI Harapan Anda Tegal. The research employed a quantitative approach with a quasi-experimental design using a one-group pretest-posttest method. A total of sixty hypertensive patients were selected through exhaustive sampling. Data were collected before and after the intervention and analyzed using the Wilcoxon test to determine the statistical significance of changes in blood pressure. The demographic characteristics of participants showed that most were in their early to mid-forties (36 individuals, 60%), predominantly female (38 individuals, 63.3%), with a junior high school education or below (25 individuals, 41.7%), and unemployed (41 individuals, 71.7%). The findings indicated that prior to the intervention, 41 participants (68.3%) had uncontrolled blood pressure. After undergoing smile therapy, 48 participants (80%) demonstrated improvement with more stable blood pressure levels. Statistical analysis revealed a significant effect of smile therapy on reducing blood pressure with a p-value of 0.000. These results suggest that smile therapy can serve as an effective, simple, and low-cost complementary intervention to help hypertensive patients manage their condition and improve overall health outcomes

Breast cancer is the leading cause of death globally, following heart disease and stroke. One of the most commonly used treatments is chemotherapy, which offers various benefits but also causes physical and mental side effects. One of the psychological side effects often experienced is anxiety. Extreme fear and the threat of death from cancer can affect adherence to treatment. This study aims to assess the relationship between anxiety levels and medication adherence in breast cancer chemotherapy patients at RSUD Semarang. This research used a quantitative approach with a descriptive correlational method, involving 110 participant samples. The questionnaires used for data collection were DASS-42 to measure anxiety levels and MMAS-8 to assess medication adherence. The study was conducted from June 30 to July 31, 2025, in the Oncology Center room of RSUD Sultan Agung Semarang. Bivariate analysis using Pearson's correlation test showed a p-value of 0.001 < 0.05, indicating a significant relationship between anxiety levels and medication adherence in breast cancer chemotherapy patients. The measured correlation coefficient of -0.325** shows a moderately strong negative relationship, meaning that the higher the anxiety level, the lower the patient's adherence to medication. Based on these findings, it is recommended that nurses in the oncology unit provide additional education and support to patients regarding their anxiety. Effective psychological support can help patients reduce anxiety and increase adherence to treatment, which in turn can improve the outcomes of chemotherapy treatment.

Patients admitted to the Intensive Care Unit (ICU) often experience physiological disturbances caused by both medical conditions and intensive treatment procedures. One of the most common problems encountered is sleep disturbance. Several factors contribute to poor sleep quality in ICU patients, including repeated medical procedures, environmental noise from medical equipment and staff activities, discomfort due to body positioning, frequent interactions with health workers, continuous exposure to lighting, pain, and the underlying disease process. Persistent sleep disturbances can delay the healing process, increase blood pressure, and even elevate the risk of stroke. This study aimed to analyze the relationship between anxiety levels and sleep quality in compos mentis patients in the ICU of Sultan Agung Islamic Hospital Semarang. The research design employed a correlational approach with a cross-sectional method. A total of 30 respondents were selected according to the inclusion criteria. Data were collected using the Pittsburgh Sleep Quality Index (PSQI) to measure sleep quality and the Hamilton Anxiety Rating Scale (HARS) to assess anxiety levels. The Chi-Square test was used for statistical analysis. The results showed an equal distribution of male and female respondents (15 each). Ten respondents had a post-laparotomy medical diagnosis, and the majority belonged to the late elderly age group (10 respondents). Most respondents experienced moderate anxiety (18 respondents), while poor sleep quality was reported by 17 respondents. The Chi-Square test revealed a p-value of 0.001, indicating a significant relationship between anxiety levels and sleep quality. In conclusion, higher anxiety levels were associated with poorer sleep quality among compos mentis patients in the ICU. These findings highlight the importance of nursing interventions that address both the physical and psychological aspects of patients to improve sleep quality and support recovery.

ST-Elevation Myocardial Infarction (STEMI) is one of the manifestations of acute coronary syndrome (ACS) and is a leading cause of disability and death worldwide. The mortality rate for STEMI is reported to reach 6%–14% of all ACS deaths. Reperfusion therapy is the primary treatment, with fibrinolytics an important option, especially in healthcare facilities that do not have the capacity to perform primary Percutaneous Coronary Intervention (PCI) in less than 12 hours. The success of fibrinolytics is influenced by various risk factors, such as hypertension, dyslipidemia, diabetes mellitus, a history of heart disease, and the duration of the attack. This study aims to determine the relationship between these factors and the success rate of fibrinolytics in STEMI patients. This study used a retrospective descriptive design with a cross-sectional method. The sampling technique used total sampling of patients diagnosed with STEMI and receiving fibrinolytic therapy according to inclusion and exclusion criteria at Dr. Fauziah Hospital. Statistical analysis was performed using the Chi-Square correlation test to assess the relationship between clinical variables and fibrinolytic success. The results showed no significant association between hyperglycemia (p = 0.823), hypertension (p = 0.240), or a history of heart disease (p = 0.704) and fibrinolytic success. Similarly, the onset of stroke variable did not show a significant association with reperfusion outcomes. In conclusion, classic risk factors such as hyperglycemia, hypertension, and a history of heart disease were not associated with fibrinolytic success in STEMI patients at Dr. Fauziah Hospital. These results suggest that fibrinolytic success is likely influenced by other factors, such as timing of drug administration, protocol adherence, and individual variation in response to therapy. Further research with a larger sample size and a prospective design is recommended to strengthen these findings.

Background: Hypertension is one of the factors that is the main cause of death for stroke sufferers and is also a factor that can aggravate heart attacks. Non-pharmacological treatment usually includes exercise, improving diet and relaxing. Autogenic relaxation is relaxation that comes from oneself by using a word or sentence that calms a person's mind and is proven to be able to control several body functions such as blood pressure and blood flow. Objective: To determine the application of autogenic relaxation to reduce blood pressure in hypertension patients in the lotus ward at RSUD dr. Soediran Mangun Sumarso Wonogiri. Method: Autogenic relaxation with patients suffering from hypertension was carried out on 2 respondents for 3 days with a duration of 15-20 minutes and blood pressure was measured before and after application. Results: It was found that there was an effect of autogenic relaxation on reducing blood pressure in the blood pressure of respondents Mrs. W 215/109 to 177/96 and Mrs. N 173/100 to 158/92. Conclusion: Based on research that has been conducted, auogenic relaxation has been proven to be significant in reducing blood pressure in hypertension patients.      

With an unhealthy lifestyle such as having a smoking habit, irregular and unhealthy eating patterns will have an impact on hypertension or high blood pressure, which later on from the bad habits above will have further impacts, namely complications of heart disease, heart failure, stroke. , and damage to the kidneys. Problems that can cause an increase in blood pressure can be controlled or prevented by using cucumber and young coconut water.To determine the effect of giving cucumber juice mixed with young coconut water on reducing blood pressure in hypertensive patients. This type of research is in the form of an experiment with a Pre Test and Post Test With Control Group Design research design. The sample in this study was 50 respondents who were divided into two groups, namely 25 samples of treatment group respondents who were given 200 grams of cucumber juice mixed with young coconut water and 25 samples of control group respondents who were not given treatment. The statistical test used to determine the effect uses the T-test. The results of this study indicate that there was an influence on blood pressure in the treatment group given cucumber juice mixed with young coconut water in hypertension sufferers, namely that the results of statistical tests obtained an average value of pre-systolic blood pressure of 161.12 mmHg and an average value of post-systolic blood pressure. systolic blood pressure was 128.48 mmHg and the average value of pre-diastolic blood pressure was 91.16 mmHg and the average value of post-diastolic blood pressure was 80.00 mmHg. A p-value of 0.000 (< 0.05) for systolic blood pressure obtained a p-value of 0.000 (< 0.05) and diastolic blood pressure obtained a p-value of 0.000 (< 0.05). Due to the benefits of cucumber and young coconut water which are beneficial for lowering blood pressure. There is an effect of giving cucumber juice mixed with young coconut water on changes in systolic and diastolic blood pressure in the treatment group and can reduce blood pressure in patients suffering from hypertension aged 40 - 70 years at Posbindu Srikandi RT.004/RW.07 Kel. Lenteng Agung.

Stroke patients are susceptible to respiratory problems and complications in the lungs, namely pneumonia, which most often occurs during stroke treatment. The aims of this study is to review the various literature on interventions that nurses can do to prevent and treat pneumonia in stroke patients. Search methods using electronic databases Science Direct, Scopus, Pubmed, and Google Scholar with a search range of 2017-2022. The inclusion criteria were research conducted on all stroke patients, both ischemic and hemorrhagic, the intervention given was a nursing action, and the outcome assessed was pneumonia. Five articles were reviewed and found several interventions used to prevent and reduce the incidence of pneumonia in stroke patients. Nursing actions that can be done are dysphagia screening and oral care. Conclusion: Dysphagia screening and and oral care can used to prevent and reduce the incidence of pneumonia in stroke patients.

Pre-hospital stroke is a service provided when and during the victim is first found, during the transportation process until the patient arrives at the hospital. Pre-hospital stroke treatment can be a determinant of the condition and subsequent treatment. The aim of this research is to determine the effect of pre-hospital education about stroke on community knowledge in carrying out pre-hospital stroke aid measures in Kombos Timur Subdistrict, Environment V, Manado City.This research is an experimental design research with a One Group pretest-posttest design. The sampling technique is purposive sampling. The sample was 15, the instrument used was a questionnaire, then the data collected was tested using the Mac-Nemar test.The research results showed that the largest gender in the study was male, with respondents (53.3%). The highest level of education was junior high school with 8 respondents (53.3%) with the highest age being adults 46-55 years as many as 7 respondents (46.7%) while the highest education was junior high school with 8 respondents (53.3%). The conclusion in this study is that there is an influence of pre-hospital education about stroke on public knowledge in carrying out pre-hospital stroke aid measures. The suggestions in this research are that it is hoped that this research will be used as a source of knowledge for patients regarding knowledge in carrying out pre-hospital stroke procedures, so that it can be applied by families at home so that this education will be more beneficial.

Background: Diabetes Mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia. Type 2 diabetes mellitus is the most common type of diabetes mellitus, accounting for about 90% of all diabetes cases. If not treated immediately can cause damage to the eyes, kidneys, heart disease, hypertension, stroke and even cause gangrene. One of the non-pharmacological treatments is progressive muscle relaxation therapy. Objective: To determine changes in blood sugar levels in patients with type 2 diabetes mellitus before and after progressive muscle relaxation therapy. Method: Descriptive method with a case study approach to 2 respondents in Jengglong Hamlet, Karanganyar Regency. The duration of giving progressive muscle relaxation therapy to respondents was 20 minutes in the morning and evening for 7 days from 25 May 2023 to 31 May 2023. Results: The blood sugar levels of the two respondents before applying progressive muscle relaxation therapy were 243 mg/dL and 255 mh/dL. After application, blood sugar levels dropped to 167 mg/dL and 221 mg/dL. Conclusion: The application of progressive muscle relaxation is able to reduce blood sugar levels in both type 2 diabetes mellitus patients in Jengglong Hamlet, Karanganyar Regency.