Publication Search

Background: Chronic Kidney Disease (CKD) patients undergoing long-term hemodialysis often experience anxiety due to therapy dependency, changes in health conditions, and uncertainty regarding the disease. Unresolved anxiety can reduce quality of life, comfort, and patient adherence to treatment. Therefore, non-pharmacological interventions are needed that are safe, easy to implement, and aligned with the patient's spiritual values. Mantram Tri Sandya has the potential to provide relaxation and psychological calm, thus helping to reduce anxiety. However, scientific evidence regarding the effectiveness of this therapy in hemodialysis patients is still limited, making this research crucial.  Purpose: The aim of this research is to determine the effect of the Tri Sandya mantra on reducing anxiety levels in CKD patients who are undergoing hemodialysis at the Buleleng Regency Regional Hospital. Methods: Pre-Experimental One Group Pre-Test & Post-Test research design with the Wilcoxon Signed Rank Test conducted at the Buleleng Regency Regional General Hospital. Data were collected using the HARS (Hamilton Anxiety Rating Scale) questionnaire sheet with Purposive Sampling technique with a sample size of 88 people. Results: The results obtained from this study were that there was a decrease in anxiety levels when given Mantra Tri Sandya therapy to CKD patients who were undergoing hemodialysis with a P value <0.001 (p<0.05). Conclusion: There is a significant effect of administering the Tri Sandy mantra on reducing anxiety levels in CKD patients who are undergoing hemodialysis at the Buleleng Regency Regional Hospital.

Diabetes melitus tipe 2 (DMT2) merupakan penyakit metabolik kronis yang ditandai oleh hiperglikemia akibat resistensi insulin dan gangguan sekresi insulin. Kondisi hiperglikemia yang tidak terkontrol dalam jangka panjang dapat menyebabkan berbagai komplikasi kronis, seperti neuropati diabetik, penyakit kardiovaskular, dan penyakit ginjal kronis hingga end-stage renal disease (ESRD). Komplikasi tersebut berkontribusi terhadap peningkatan angka morbiditas, mortalitas, serta penurunan kualitas hidup pasien. Laporan kasus ini bertujuan untuk menggambarkan manifestasi klinis dan penatalaksanaan pasien DMT2 tidak terkontrol dengan komplikasi multisistem. Dilaporkan seorang wanita berusia 52 tahun dengan riwayat DMT2 tidak terkontrol yang datang dengan keluhan lemas, mual, dan muntah. Pemeriksaan laboratorium menunjukkan hiperglikemia berat dengan kadar glukosa darah sewaktu 650 mg/dL, disertai gangguan fungsi ginjal, anemia, dan gangguan elektrolit. Pemeriksaan ultrasonografi abdomen menunjukkan adanya kolesistitis. Pasien didiagnosis dengan DMT2 tidak terkontrol disertai komplikasi hiperglikemia berat, neuropati diabetik, end-stage chronic kidney disease, dan kolesistitis. Penatalaksanaan dilakukan melalui pemberian terapi cairan, insulin, antibiotik, koreksi elektrolit, serta terapi suportif lainnya. Selama perawatan, kondisi klinis pasien menunjukkan perbaikan secara bertahap. Kasus ini menegaskan bahwa pengendalian glikemik yang optimal, pemantauan rutin, serta penatalaksanaan komprehensif sangat penting dalam mencegah progresivitas komplikasi kronis dan multisistem pada pasien DMT2.

A chronic metabolic disease characterized by elevated blood glucose levels due to insulin resistance or impaired insulin secretion is classified as type 2 diabetes mellitus. The prevalence of diabetes continues to rise each year and has become one of the major challenges in global health due to its potential to cause serious complications, such as cardiovascular disease, kidney failure, neuropathy, and vision impairment. In addition to pharmacological therapy, the use of herbal plants is increasingly being developed as a complementary therapy because they are considered safer, more readily available, and contain bioactive compounds with potential antidiabetic properties. This review article aims to assess the effectiveness of several herbal plants namely cinnamon (Cinnamomum cassia), fenugreek (Trigonella foenum-graecum), bitter melon (Momordica charantia), and moringa (Moringa oleifera) in aiding the management of type 2 diabetes mellitus based on various research findings. This study employs a literature review method by collecting and analyzing various national and international scientific publications related to the antidiabetic activity of these four plants. The review results indicate that all plants have potential as adjunct therapies for diabetes because they contain active compounds such as flavonoids, polyphenols, cinnamaldehyde, charantin, quercetin, trigonelline, and saponins, which can help reduce blood glucose levels, optimize cellular response to insulin, increase GLUT4 activity, and help minimize oxidative damage. Based on the study results, moringa and cinnamon plants demonstrated the most consistent effectiveness in contributing to blood sugar control in individuals with type 2 diabetes mellitus. Thus, these herbal plants have the potential to be used as complementary therapies in the management of type 2 diabetes mellitus; however, their use must still adhere to proper dosing and should not replace primary medical therapy.

A chronic metabolic disease characterized by elevated blood glucose levels due to insulin resistance or impaired insulin secretion is classified as type 2 diabetes mellitus. The prevalence of diabetes continues to rise each year and has become one of the major challenges in global health due to its potential to cause serious complications, such as cardiovascular disease, kidney failure, neuropathy, and vision impairment. In addition to pharmacological therapy, the use of herbal plants is increasingly being developed as a complementary therapy because they are considered safer, more readily available, and contain bioactive compounds with potential antidiabetic properties. This review article aims to assess the effectiveness of several herbal plants namely cinnamon (Cinnamomum cassia), fenugreek (Trigonella foenum-graecum), bitter melon (Momordica charantia), and moringa (Moringa oleifera) in aiding the management of type 2 diabetes mellitus based on various research findings. This study employs a literature review method by collecting and analyzing various national and international scientific publications related to the antidiabetic activity of these four plants. The review results indicate that all plants have potential as adjunct therapies for diabetes because they contain active compounds such as flavonoids, polyphenols, cinnamaldehyde, charantin, quercetin, trigonelline, and saponins, which can help reduce blood glucose levels, optimize cellular response to insulin, increase GLUT4 activity, and help minimize oxidative damage. Based on the study results, moringa and cinnamon plants demonstrated the most consistent effectiveness in contributing to blood sugar control in individuals with type 2 diabetes mellitus. Thus, these herbal plants have the potential to be used as complementary therapies in the management of type 2 diabetes mellitus; however, their use must still adhere to proper dosing and should not replace primary medical therapy.

Chronic Kidney Disease (CKD) represents a significant global health challenge, with a trend of steadily rising prevalence, including in Indonesia. Patients with CKD undergoing routine hemodialysis face multidimensional challenges that impact their quality of life. This literature review aims to outline and synthesize factors associated with the quality of life of CKD patients undergoing hemodialysis in Indonesia. A systematic literature review method using the PRISMA approach was employed, involving searches across Google Scholar, PubMed, Garuda, and DOAJ databases. Inclusion criteria covered articles with a cross-sectional analytical observational design involving patients with advanced-stage CKD undergoing hemodialysis, published within the last ten years, and utilizing valid and reliable quality-of-life instruments (WHOQOL-BREF, KDQOL-SF, KDQOL-36). A total of 21 national and international articles were selected through a systematic process, and their methodological quality was assessed via mapping and scoring stages. The results highlight various aspects consistently and strongly associated with the quality of life of CKD patients, including: (1) clinical factors such as the duration of hemodialysis and comorbidities; (2) psychosocial factors such as anxiety, depression, family support, motivation, and fatigue; and (3) sociodemographic factors such as education level and economic status. Depression emerged as the most dominant predictor with the highest odds ratio (OR=10.131), followed by the duration of hemodialysis (OR=8.380) and comorbidities (OR=5.044). It is concluded that the quality of life of CKD patients is multidimensional and influenced by the interaction of clinical, psychological, and social factors. Integrated interventions—encompassing routine psychological screening, the strengthening of family support, and comorbidity management—are essential to improving the quality of life for CKD patients in Indonesia.

Chronic kidney disease is a progressive disease requiring long-term hemodialysis therapy that may cause physical, psychological, social, and spiritual problems. Patients undergoing hemodialysis often experience spiritual distress due to changes in health conditions and dependence on therapy. This study aimed to determine the relationship between the duration of hemodialysis and the level of spiritual distress in chronic kidney disease patients at the Hemodialysis Unit of Baiturrahim Hospital Jambi. This study used a quantitative design with a cross sectional approach. The sample consisted of 57 respondents selected using a purposive sampling technique. The research instrument used a spiritual distress questionnaire that had been tested for validity and reliability with a Cronbach’s Alpha value of 0.955. Data were analyzed using the Chi-Square test with a significance level of 0.05. The results showed that most respondents underwent hemodialysis for ≥12 months, totaling 39 respondents (68.4%), and the majority experienced moderate spiritual distress, totaling 20 respondents (35.1%). Statistical analysis showed a p-value of 0.030 (p<0.05), indicating a significant relationship between the duration of hemodialysis and the level of spiritual distress in chronic kidney disease patients. The longer patients undergo hemodialysis, the lighter the spiritual distress tends to be because patients gradually adapt to their disease condition and therapy.

Chronic kidney disease is a progressive decline in kidney function that leads to fluid and electrolyte imbalance, requiring fluid restriction which often causes thirst and may result in ineffective peripheral perfusion. One non-pharmacological nursing intervention that can be applied is the ice cube sucking technique as part of fluid management. This study aimed to analyze the implementation of education the ice cube sucking technique in improving fluid management and peripheral perfusion in elderly patients with chronic kidney disease. The study used a descriptive case study design with a nursing process approach conducted over three sessions in an elderly patient with chronic kidney disease. The intervention was delivered in three sessions, each lasting approximately 15–20 minutes. The results showed a reduction in thirst complaints, improvement in peripheral perfusion indicated by capillary refill time of less than 2 seconds and warm extremities, as well as increased patient and family ability in managing fluid intake. In conclusion, the ice cube sucking technique are effective nursing interventions in fluid management and improving peripheral perfusion in patients with chronic kidney disease.

Chronic kidney disease is a progressive decline in kidney function that leads to fluid and electrolyte imbalance, requiring fluid restriction which often causes thirst and may result in ineffective peripheral perfusion. One non-pharmacological nursing intervention that can be applied is the ice cube sucking technique as part of fluid management. This study aimed to analyze the implementation of education the ice cube sucking technique in improving fluid management and peripheral perfusion in elderly patients with chronic kidney disease. The study used a descriptive case study design with a nursing process approach conducted over three sessions in an elderly patient with chronic kidney disease. The intervention was delivered in three sessions, each lasting approximately 15–20 minutes. The results showed a reduction in thirst complaints, improvement in peripheral perfusion indicated by capillary refill time of less than 2 seconds and warm extremities, as well as increased patient and family ability in managing fluid intake. In conclusion, the ice cube sucking technique are effective nursing interventions in fluid management and improving peripheral perfusion in patients with chronic kidney disease.

Chronic kidney disease is one of the global health problems that requires long-term therapy, one of which is through hemodialysis. According to the World Health Organization (WHO), adherence to treatment and diet is a key factor in improving the quality of life for patients with chronic diseases. An appropriate diet plays an important role in controlling electrolyte levels, fluids, and toxic substances in the body. This study aims to describe the knowledge and dietary compliance of patients undergoing hemodialysis at Santa Elisabeth Hospital Medan in 2025.This research used a descriptive quantitative design with a cross-sectional approach. The sample consisted of 36 patients selected using purposive sampling techniques. The research instrument was a questionnaire developed based on dietary guidelines for hemodialysis patients according to WHO and the Indonesian Ministry of Health standards. The results showed that among the 36 hemodialysis patients, 15 respondents (41.7%) had a good level of knowledge, 14 respondents (38.9%) had a moderate level, and 7 respondents (19.4%) had a low level of knowledge. Regarding dietary compliance, 13 respondents (36.1%) were compliant, 18 respondents (50.0%) were moderately compliant, and 3 respondents (13.9%) were non-compliant. There was a tendency showing that higher knowledge levels were positively correlated with better dietary compliance, in line with WHO’s principle that health education is an essential intervention in managing chronic diseases. This study recommends strengthening ongoing educational programs by healthcare professionals, particularly in delivering accurate and easy-to-understand information about diet management for hemodialysis patients.

Chronic kidney disease is one of the global health problems that requires long-term therapy, one of which is through hemodialysis. According to the World Health Organization (WHO), adherence to treatment and diet is a key factor in improving the quality of life for patients with chronic diseases. An appropriate diet plays an important role in controlling electrolyte levels, fluids, and toxic substances in the body. This study aims to describe the knowledge and dietary compliance of patients undergoing hemodialysis at Santa Elisabeth Hospital Medan in 2025.This research used a descriptive quantitative design with a cross-sectional approach. The sample consisted of 36 patients selected using purposive sampling techniques. The research instrument was a questionnaire developed based on dietary guidelines for hemodialysis patients according to WHO and the Indonesian Ministry of Health standards. The results showed that among the 36 hemodialysis patients, 15 respondents (41.7%) had a good level of knowledge, 14 respondents (38.9%) had a moderate level, and 7 respondents (19.4%) had a low level of knowledge. Regarding dietary compliance, 13 respondents (36.1%) were compliant, 18 respondents (50.0%) were moderately compliant, and 3 respondents (13.9%) were non-compliant. There was a tendency showing that higher knowledge levels were positively correlated with better dietary compliance, in line with WHO’s principle that health education is an essential intervention in managing chronic diseases. This study recommends strengthening ongoing educational programs by healthcare professionals, particularly in delivering accurate and easy-to-understand information about diet management for hemodialysis patients.

Ballast water plays a crucial role in maintaining ship stability during shipping, but it also carries environmental and human health risks due to the heavy metals it carries. This study aims to examine the health risks posed by exposure to heavy metals in ballast water and to assess the effectiveness of management practices implemented in the maritime industry. Using a literature review method, this study examines various scientific sources related to the content of heavy metals such as lead (Pb), cadmium (Cd), copper (Cu), and zinc (Zn) in ballast water, as well as their impacts on human health and marine ecosystems. The results indicate that heavy metals in ballast water can cause long-term toxic effects such as neurological disorders, kidney damage, and respiratory and reproductive disorders. The greatest risk is experienced by maritime workers who are directly exposed through inhalation or skin contact during the ballast water sampling and processing process. To minimize these risks, strict work safety protocols, improved ballast water treatment technology, and regular monitoring of heavy metal levels are required. Thus, this study emphasizes the importance of strengthening ballast water management policies and practices that are oriented towards human health and environmental sustainability.  

Chronic Kidney Disease (CKD) is a structural or functional abnormality of the kidneys that lasts ≥3 months with the criteria of eGFR <60 mL/min/1.73 m² or the presence of kidney damage such as albuminuria and urinary abnormalities (Kidney International, 2024). CKD patients, especially those treated in intensive care units, often experience gastrointestinal disorders such as increased volume of gastric residues. Giving enteral nutrition to patients with NGT can increase the volume of gastric residue which is at risk of causing complications. One of the non-pharmacological interventions that can be carried out is abdominal massage, which is a light massage technique in the abdominal area that can stimulate intestinal peristalsis and improve gastrointestinal motility. The purpose of this case study was to determine the effect of  giving abdominal massage on reducing the volume of gastric residue in CKD patients in the ICU. This scientific paper uses a case study design using abdominal mass therapy. The number of respondents was 3 people, the intervention was carried out for 3 days with a time of 10-15 minutes. The application of abdominal massage therapy in the three respondents showed a decrease in the volume of gastric residue after admixture was carried out  for three consecutive days with an average decrease in the volume of gastric residue, which was 50 cc - 75 cc. Abdominal massage is a safe and effective nonpharmacological nursing intervention to help reduce gastric residue volume and support enteral nutrient tolerance in CKD patients in the ICU.

Chronic Kidney Disease (CKD) is a growing global health concern that significantly affects patients’ quality of life. At Bhakti Asih General Hospital, Tangerang, the number of hemodialysis patients increased by 20.42% and dialysis procedures by 25.06% between 2023 and 2024. Despite this service expansion, preliminary findings revealed that 32% of patients reported poor quality of life, 31% experienced low engagement in care, 34% demonstrated low self-efficacy particularly in dietary and fluid management and 32% faced accessibility barriers. These findings indicate a gap between increased service volume and patient-centered outcomes. This study aimed to analyze the effects of patient engagement and self-efficacy on the quality of life of hemodialysis patients, with healthcare accessibility as a mediating variable. A quantitative cross-sectional design was employed. Active hemodialysis patients were selected using purposive sampling. Data were collected through structured questionnaires and analyzed using Structural Equation Modeling (SEM).The results demonstrated that patient engagement and self-efficacy had significant positive effects on quality of life, both directly and indirectly through accessibility. Accessibility also significantly influenced quality of life and strengthened the relationships between patient engagement, self-efficacy, and quality of life.These findings highlight the importance of integrating patient engagement strategies, strengthening self-efficacy through education, and improving service accessibility to enhance quality of life among hemodialysis patients

Hypertension has become a chronic disease known as the silent killer because it often does not show symptoms but can cause serious complications such as stroke, heart disease, and kidney failure. According to WHO, hypertension is one of the leading causes of death worldwide and its prevalence continues to rise. Sleep disturbances can increase sympathetic nervous system activity and stress hormones, which impact blood pressure elevation. Depression is characterized by prolonged feelings of sadness, loss of interest, and decreased energy. Physiologically, depression can increase stress hormones and cause autonomic nervous system imbalance, leading to elevated blood pressure. To determine the relationship between sleep pattern disturbances and depression levels with blood pressure in hypertensive patients in the outpatient department of RS Permata Medika Semarang. Quantitative research with a correlational design using a cross-sectional approach. The sampling technique used was consecutive sampling with a sample size of 79 respondents. The instruments used are the PSQI questionnaire for sleep pattern disturbances and the DASS-42 for depression levels. Ethics test no 03/EC-LPPM/UWHS/II-2026. Data analysis used the Spearman Rank test. The research results show that there is a significant relationship between sleep pattern disturbances and blood pressure in hypertensive patients (p=0.000; rho=0.826). Respondents with poor sleep patterns mostly have high blood pressure, indicating a very strong and positive relationship, where the worse the sleep pattern, the more uncontrolled the blood pressure tends to be. Additionally, there is a significant relationship between the level of depression and blood pressure (p=0.000; rho=0.808). Respondents with severe and very severe depression mostly have high blood pressure, which means that the higher the level of depression, the more the blood pressure increases or becomes uncontrolled. There is a relationship between sleep pattern disturbances and depression levels with blood pressure in hypertensive patients in the outpatient department of Permata Medika Hospital Semarang.

The use of medicinal plants has been an important part of people's lives since the time of our ancestors. Before the advent of modern medicine, people used various types of plants to treat mild to severe illnesses, such as fever, cough, wounds, digestive disorders, and skin diseases. Inventory of medicinal plants plays a very important role in exploring the potential of existing natural resources, especially as an effort to support the development of traditional medicine. The purpose of this study is to identify the types of medicinal plants used by local communities in traditional medicine. The method used in this study is a descriptive method through direct surveys at the research location. The findings obtained in the field concluded that all types of plants mentioned in this study are very beneficial for the people of Duhiadaa District, because they can help in treating various types of diseases experienced by the community. The types of diseases that can be treated include hypertension, gout, stomach acid, cholesterol, kidney disease, diabetes, inflammation, cancer, wounds, diarrhea and digestive disorders.

Patient satisfaction influences their desire to return to the same place, and if they are not satisfied, they will look for another place of health, prolonged helminths will result in patients experiencing psychological disorders and will result in the decline of patients caused by the threat of death, overall economic problems and medical problems. Cognitive factors can influence the health and well-being of patients with kidney failure because patients with kidney failure can feel psychologically tired because they have to undergo hemodialysis. The aim of this research is to determine the description of patient satisfaction undergoing hemodialysis at Santa Elisabeth Hospital. The design method for clinical treatment is delscrilptilf which will analyze or observe a picture of the population of patients who underwent hemodilalization at Rulmah Hospital Santa Ellilsabelth with a sample size of 50 respondents. The total sampling technique was taken. Research Results The results of this research were to determine the description of patient satisfaction undergoing hemodialysis at Santa Elisabeth Hospital in Medan with a total of 50 respondents. Where the research uses tables and provides an explanation of the frequency distribution of characteristics based on age, gender, religion, occupation, marital status, education. And this research was obtained from primary data obtained from the respondents themselves. After the data is obtained, it is processed and the results will be analyzed using univariate analysis.

Hypertension contributes to numerous complications such as heart disease, stroke, kidney failure, and is a risk factor of disability and death. Hypertension Prevalence in Jatinangor is 37.8%, that is higher than national rate. The control of hypertension is low and the education at the primary health facility is short. Therefore, another buffer system for education such as posbindu is needed. Activities that educate people with hypertension become very important, but need to be adjusted as needs. Aim of this study is to determine form and intensity of education preferred by hypertension patients Method: Qualitative descriptive with case study approach using focused group discussion (FGD) method, led by main moderator and assisted by a second moderator. Participants consisted of 15 people with hypertension chosen purposively with the inclusion criterias female and parallel to the research objective. The discussion used semi-structured questions. This study is conducted in two villages in Jatinangor, Desa Cipacing and Desa Cilayung from February to May 2017. Results: Participants wanted education in the form of traditional learning, game simulation, written notes, and video recording. The intensity of education preferred until patients understand, it tends to be performed more than once, and preferred place are performed within Posyandu (Integrated Health and Nutrition Post) with education frequency varies from once a week to once a month. Conclusion: Hypertension patients have variable preference of education forms and its intensity. Innovations in the development of methods in accordance with hypertension patients’ needs must be continued, so that interventions can become more effective for hypertension patients.

Food Additives (BTP) in current consumer products increase the risk of non-communicable diseases such as diabetes, kidney failure, and cancer, particularly in children. Housewives play a central role in managing family consumption to minimize these risks. This community service activity aims to enhance the knowledge and awareness of 'Aisyiyah women in Buluspesantren, Kebumen Regency, regarding food safety and BTP regulations. The implementation method included preparing materials based on BPOM regulations, interactive education, product discussions, and simulations on reading nutrition labels. The results showed high enthusiasm from participants who are now more critical in distinguishing between natural and synthetic additives. Participants reported a significant improvement in their ability to identify food ingredients and additives in everyday products. The final evaluation recorded a 22.2-point increase in participant understanding. By establishing the habit of reading food labels, it is expected that the risk of non-communicable diseases within the family environment can be reduced, thus improving public health literacy and dietary choices within the community.

Indonesia faces various metabolic health problems that are often associated with food and beverage consumption, including chronic kidney disease. One contributing factor is the excessive use of food preservatives such as sodium benzoate, which may cause gastrointestinal disturbances, oxidative stress, inflammation, chronic kidney failure, and carcinogenic effects. This study aimed to determine the relationship between sellers’ knowledge level and the use of sodium benzoate preservative in jumbo iced tea sold in Kedungmundu and Sendangmulyo Subdistricts, Semarang City. The study employed an analytic quantitative method with a cross-sectional design. A total of 40 jumbo iced tea sellers were selected using simple random sampling. Sodium benzoate testing was conducted using UV-Visible spectrophotometry, and data were analyzed using Spearman’s rho correlation test. The results showed that 70% of respondents had a high level of knowledge, while 5% of samples were positive for sodium benzoate. Statistical analysis revealed a significant inverse relationship between sellers’ knowledge level and the use of sodium benzoate (p = 0.011; r = -0.397). This indicates that higher knowledge levels are associated with a lower likelihood of sodium benzoate use. In conclusion, there is a significant negative correlation between sellers’ knowledge and the use of sodium benzoate in jumbo iced tea.

Diuretic resistance is a serious complication in heart failure patients associated with increased morbidity and mortality. Tolvaptan, a vasopressin V2 receptor antagonist, offers an alternative therapeutic mechanism through aquaresis. This study aims to evaluate the effectiveness and safety of tolvaptan in heart failure patients with diuretic resistance. A retrospective cohort study was conducted on 58 hospitalized patients with NYHA III-IV heart failure and diuretic resistance (urine output <1000 mL/day despite furosemide use ≥80 mg/day) who received tolvaptan 7.5-15 mg/day for 7 days. Variables measured included weight change, urine output, serum sodium, and kidney function. The results showed a significant increase in daily urine output from 820±230 mL to 2180±520 mL (p<0.001), along with an average weight loss of 3.4±1.1 kg (p<0.001). Hypernatremia (>145 mEq/L) occurred in 8.6% of patients. In conclusion, tolvaptan is effective in improving diuresis and reducing congestion in heart failure patients with diuretic resistance, although the risk of hypernatremia should be monitored.