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Canker sores are an inflammation of the oral tissues, generally caused by bacterial and fungal infections. They can cause pain and discomfort and reduce the sufferer's quality of life. Treatment for canker sores has been dominated by synthetic drugs, but they are less popular among the public, especially children, due to discomfort and concerns about side effects. Therefore, we need safer and more easily accepted alternative treatments based on culturally derived materials. This study is to investigate the potential of pineapple and melon stems formulated in the form of gummy candy nanosimplicia as a complementary therapy in the treatment of canker sores. The research method was carried out through a literature review by collecting scientific articles from the PubMed, ScienceDirect, and Google Scholar databases, then analyzed using VOSviewer software to map emerging research trends and potential. The analysis results indicate that there are approximately 600 articles discussing the active metabolite content in pineapple and melon stems that have antibacterial and antifungal activity, as well as the development of innovative preparations such as gummy candy as a delivery medium for bioactive compounds. The implications of this study indicate that the combination of pineapple stem and melon nanosimplisia has the potential to be developed as a safe, attractive, and effective natural herbal candy product for the prevention and treatment of mouth ulcers, especially in children.

Exposure to cigarette smoke is one of the environmental risk factors that is still widely found and has a significant impact on the health of the respiratory system, especially the upper respiratory tract. The irritants and toxic substances in cigarette smoke can trigger mucosal inflammation, interfere with the defenses of the airways, and increase susceptibility to various upper airway disorders. This study aims to systematically analyze the relationship between cigarette smoke exposure and upper airway disorders based on available scientific evidence. The method used is Systematic Literature Review (SLR) with reference to the PRISMA 2020 guidelines. Literature searches were conducted through PubMed, ScienceDirect, Google Scholar, and Garuda databases. Articles were selected based on inclusion and exclusion criteria, resulting in 26 articles that were analyzed narrative-synthesis. The results showed that most studies reported a meaningful association between exposure to cigarette smoke, both in active and passive smokers, and an increased risk of upper respiratory tract disorders such as rhinitis, sinusitis, recurrent upper respiratory tract infections, pharyngitis, and laryngitis. Higher risks are found in passive smokers, especially children, as well as in individuals with long-term, high-intensity exposure. The conclusion of this study confirms that exposure to cigarette smoke is an important and preventable risk factor for upper respiratory tract disorders. Therefore, it is necessary to strengthen the policy of non-smoking areas, public education, as well as promotive and preventive efforts in health services to reduce the impact of exposure to cigarette smoke on the health of the upper respiratory tract.

Choking is a dangerous thing for children, especially children with special needs who require proper handling, and parents as the closest people to the child must have first aid skills for choking. The purpose of this study is to determine the effect of ANSIVI (Animation and Simulation Video) Choking Management on parents' ability in first aid for choking. The research design was a pre-experimental design with a one-group pretest-posttest approach without control. The purposive sampling technique obtained 36 respondents. The research instrument used an observation sheet for first aid for choking. The statistical test was the Wilcoxon Signed Rank Test with α 0.05. The results of the study before being given the ANSIVI (Animation and Simulation Video) Choking Management intervention showed that all (100%) respondents had insufficient ability, and after the intervention the majority (52.8%) of respondents had sufficient ability. The results of the statistical analysis obtained a p-value of 0.013 < α 0.05, so there is an effect of ANSIVI (Animation and Simulation Video) choking management on parents' ability in first aid for choking. The ANSIVI method (Video Animation and Simulation) combines two methods so that it is more interesting, interactive, and effective because the video is captured by the eyes and ears and then will be detected and converted into signals to the optic nerve and auditory nerve and forwarded to the brain, program area, and frontal area to be associated so that it will affect the respondent's ability. The ANSIVI method can be used in education for all parents and school residents as a first aid effort for choking, especially for children with special needs.