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This meta-analysis investigated the effect of life satisfaction on Sarcoidosis treatment outcomes across 47 studies encompassing 8,932 patients. The findings revealed a significant positive correlation between life satisfaction and treatment success (r = 0.62, p < 0.001). Patients with high life satisfaction scores (>7.5/10) demonstrated a 73% higher likelihood of achieving remission compared to those with low scores (<5/10) (OR = 2.84, 95% CI: 2.31-3.49). Regression analysis indicated that each one-point increase in life satisfaction scores was associated with an 18% reduction in Sarcoidosis relapse rates (β = -0.18, p = 0.002). Treatment adherence and health behaviors were found to mediate the relationship between life satisfaction and Sarcoidosis treatment outcomes, accounting for 42% and 35% of the variance, respectively. Moderator analyses demonstrated stronger effects among patients with disease duration <5 years (p = 0.011) and those with mild to moderate disease severity (p = 0.003). These findings extend the work of Lee et al. (2020) and Martínez-García et al. (2021) by demonstrating a more pronounced effect of life satisfaction on Sarcoidosis treatment compared to other chronic conditions. Notably, contrary to Saketkoo et al (2021) previous study, the effect of life satisfaction remained significant even after controlling for patients' socioeconomic factors (β = 0.41, p < 0.001). These results underscore the crucial role of psychosocial interventions in enhancing Sarcoidosis treatment efficacy, offering new perspectives in the management of this chronic condition.

This meta-analysis examined the relationship between social support and medication adherence among multiple sclerosis (MS) patients through a synthesis of 47 studies (N=12,356). The findings confirmed a significant positive correlation (r=0.42, p<0.001, 95% CI [0.38, 0.46]) with substantial heterogeneity (I²=84.0%). Contrary to Cohen et al.'s (2019) finding that informational support was the strongest predictor, our moderator analyses revealed emotional support as the most robust predictor (β=0.39, p<0.001). Furthermore, this research demonstrated that the effects of social support on MS medication adherence were stronger among women (β=0.18, p=0.023) and patients with longer disease duration (β=0.24, p=0.009), extending Franqueiro et al.'s (2023) findings regarding gender differences in social support effectiveness. Family support showed the largest effect (r=0.48, p<0.001), followed by friends (r=0.40, p<0.001) and healthcare providers (r=0.35, p<0.001). Moreover, mediation modeling revealed a significant role of self-efficacy (indirect effect=0.21, 95% CI [0.17, 0.25]), expanding upon Bandura's (2018) model. Supporting Lavorgna et al.'s (2018) findings, our results confirmed that online social support proved equally effective as offline support (Q=1.87, p=0.171). These findings demonstrated robustness through sensitivity analyses and trim-and-fill procedures, confirming resilience against publication bias (adjusted r=0.39, 95% CI [0.35, 0.43]). The novelty of this research lies in its comprehensive identification of key moderators and underlying mechanisms in the social support-medication adherence relationship and the first empirical testing of an integrated mediation model incorporating social support, self-efficacy, and medication adherence in the MS context.

This research departs from the phenomenon that occurs in families in the Kenagarian Koto Kaciak area, Tanjung Raya District, Agam Regency, the majority of the population in this area is of productive age, most of them are busy with their own work so they pay less attention and control over their children's development. Even though they have families and children who still need guidance, direction and love. One of the causes of children's behavior that is deviant or not in accordance with applicable rules is inappropriate parenting patterns in the family, as well as parents' lack of education and knowledge about religion. This can be seen from the treatment of parents towards their children. This research is research (file research) which is descriptive qualitative in nature. The key informants in this research were parents and the supporting informants were 10 teenagers. Data collection techniques were obtained through observation and interviews. The collected data was analyzed using data analysis techniques sourced from observations and interviews. The validity of the data obtained was tested using triangulation. Based on the research results, it can be concluded that the parenting style applied by parents will influence children's attitudes and behavior both in the family, social and community environments. If the parenting style is right, then the behavior displayed by the child will be in accordance with what the parents expect and vice versa, the child's behavior will be deviant and contrary to existing rules. All of this is influenced by parents' busy lives which results in a lack of attention to children in controlling their development, relationships and daily life. The efforts made by parents are trying to implement appropriate parenting patterns according to their children's development and trying to pay more attention, providing good guidance and direction in living their daily lives to their children, so that children realize that they live within the rules. which must be obeyed and have a sense of responsibility.

Diabetes Mellitus (DM) is a metabolic disease with hyperglycemia characteristics that occurs because abnormality of insulin secretion . Diabetes mellitus can cause eye damage . Study this aim to know the correlation of stability of blood sugar levels with decreased visual acuity in type II diabetes mellitus.This study use analytical study design correlation with approach cross sectional. The technique used purposive with 52 respondents who meet the criteria. The analysis of the data used test Chi-Square. The results of study showed that for stability rate sugar blood of 29 respondents are unstable. Decrease in visual acuity of 23 respondents were in moderate category. The results of the chi-square test of the stability of blood sugar levels with decreased visual acuity in Diabetes Mellitus type II obtained p value = 0.00 0 so that the p -value < = 0.05 . The results of this study indicate a relationship between the stability of blood sugar levels with decreased visual acuity.It can be concluded that unstable blood sugar levels can affect the decrease in visual acuity in Diabetes Mellitus. On the contrary, if blood sugar levels are in a stable range, the risk of decreased visual acuity will decrease.