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Background: Chronic Kidney Disease (CKD) patients undergoing long-term hemodialysis often experience anxiety due to therapy dependency, changes in health conditions, and uncertainty regarding the disease. Unresolved anxiety can reduce quality of life, comfort, and patient adherence to treatment. Therefore, non-pharmacological interventions are needed that are safe, easy to implement, and aligned with the patient's spiritual values. Mantram Tri Sandya has the potential to provide relaxation and psychological calm, thus helping to reduce anxiety. However, scientific evidence regarding the effectiveness of this therapy in hemodialysis patients is still limited, making this research crucial.  Purpose: The aim of this research is to determine the effect of the Tri Sandya mantra on reducing anxiety levels in CKD patients who are undergoing hemodialysis at the Buleleng Regency Regional Hospital. Methods: Pre-Experimental One Group Pre-Test & Post-Test research design with the Wilcoxon Signed Rank Test conducted at the Buleleng Regency Regional General Hospital. Data were collected using the HARS (Hamilton Anxiety Rating Scale) questionnaire sheet with Purposive Sampling technique with a sample size of 88 people. Results: The results obtained from this study were that there was a decrease in anxiety levels when given Mantra Tri Sandya therapy to CKD patients who were undergoing hemodialysis with a P value <0.001 (p<0.05). Conclusion: There is a significant effect of administering the Tri Sandy mantra on reducing anxiety levels in CKD patients who are undergoing hemodialysis at the Buleleng Regency Regional Hospital.

A chronic metabolic disease characterized by elevated blood glucose levels due to insulin resistance or impaired insulin secretion is classified as type 2 diabetes mellitus. The prevalence of diabetes continues to rise each year and has become one of the major challenges in global health due to its potential to cause serious complications, such as cardiovascular disease, kidney failure, neuropathy, and vision impairment. In addition to pharmacological therapy, the use of herbal plants is increasingly being developed as a complementary therapy because they are considered safer, more readily available, and contain bioactive compounds with potential antidiabetic properties. This review article aims to assess the effectiveness of several herbal plants namely cinnamon (Cinnamomum cassia), fenugreek (Trigonella foenum-graecum), bitter melon (Momordica charantia), and moringa (Moringa oleifera) in aiding the management of type 2 diabetes mellitus based on various research findings. This study employs a literature review method by collecting and analyzing various national and international scientific publications related to the antidiabetic activity of these four plants. The review results indicate that all plants have potential as adjunct therapies for diabetes because they contain active compounds such as flavonoids, polyphenols, cinnamaldehyde, charantin, quercetin, trigonelline, and saponins, which can help reduce blood glucose levels, optimize cellular response to insulin, increase GLUT4 activity, and help minimize oxidative damage. Based on the study results, moringa and cinnamon plants demonstrated the most consistent effectiveness in contributing to blood sugar control in individuals with type 2 diabetes mellitus. Thus, these herbal plants have the potential to be used as complementary therapies in the management of type 2 diabetes mellitus; however, their use must still adhere to proper dosing and should not replace primary medical therapy.

A chronic metabolic disease characterized by elevated blood glucose levels due to insulin resistance or impaired insulin secretion is classified as type 2 diabetes mellitus. The prevalence of diabetes continues to rise each year and has become one of the major challenges in global health due to its potential to cause serious complications, such as cardiovascular disease, kidney failure, neuropathy, and vision impairment. In addition to pharmacological therapy, the use of herbal plants is increasingly being developed as a complementary therapy because they are considered safer, more readily available, and contain bioactive compounds with potential antidiabetic properties. This review article aims to assess the effectiveness of several herbal plants namely cinnamon (Cinnamomum cassia), fenugreek (Trigonella foenum-graecum), bitter melon (Momordica charantia), and moringa (Moringa oleifera) in aiding the management of type 2 diabetes mellitus based on various research findings. This study employs a literature review method by collecting and analyzing various national and international scientific publications related to the antidiabetic activity of these four plants. The review results indicate that all plants have potential as adjunct therapies for diabetes because they contain active compounds such as flavonoids, polyphenols, cinnamaldehyde, charantin, quercetin, trigonelline, and saponins, which can help reduce blood glucose levels, optimize cellular response to insulin, increase GLUT4 activity, and help minimize oxidative damage. Based on the study results, moringa and cinnamon plants demonstrated the most consistent effectiveness in contributing to blood sugar control in individuals with type 2 diabetes mellitus. Thus, these herbal plants have the potential to be used as complementary therapies in the management of type 2 diabetes mellitus; however, their use must still adhere to proper dosing and should not replace primary medical therapy.

Chronic kidney disease is a progressive disease requiring long-term hemodialysis therapy that may cause physical, psychological, social, and spiritual problems. Patients undergoing hemodialysis often experience spiritual distress due to changes in health conditions and dependence on therapy. This study aimed to determine the relationship between the duration of hemodialysis and the level of spiritual distress in chronic kidney disease patients at the Hemodialysis Unit of Baiturrahim Hospital Jambi. This study used a quantitative design with a cross sectional approach. The sample consisted of 57 respondents selected using a purposive sampling technique. The research instrument used a spiritual distress questionnaire that had been tested for validity and reliability with a Cronbach’s Alpha value of 0.955. Data were analyzed using the Chi-Square test with a significance level of 0.05. The results showed that most respondents underwent hemodialysis for ≥12 months, totaling 39 respondents (68.4%), and the majority experienced moderate spiritual distress, totaling 20 respondents (35.1%). Statistical analysis showed a p-value of 0.030 (p<0.05), indicating a significant relationship between the duration of hemodialysis and the level of spiritual distress in chronic kidney disease patients. The longer patients undergo hemodialysis, the lighter the spiritual distress tends to be because patients gradually adapt to their disease condition and therapy.

Chronic kidney disease is a progressive decline in kidney function that leads to fluid and electrolyte imbalance, requiring fluid restriction which often causes thirst and may result in ineffective peripheral perfusion. One non-pharmacological nursing intervention that can be applied is the ice cube sucking technique as part of fluid management. This study aimed to analyze the implementation of education the ice cube sucking technique in improving fluid management and peripheral perfusion in elderly patients with chronic kidney disease. The study used a descriptive case study design with a nursing process approach conducted over three sessions in an elderly patient with chronic kidney disease. The intervention was delivered in three sessions, each lasting approximately 15–20 minutes. The results showed a reduction in thirst complaints, improvement in peripheral perfusion indicated by capillary refill time of less than 2 seconds and warm extremities, as well as increased patient and family ability in managing fluid intake. In conclusion, the ice cube sucking technique are effective nursing interventions in fluid management and improving peripheral perfusion in patients with chronic kidney disease.

Chronic kidney disease is a progressive decline in kidney function that leads to fluid and electrolyte imbalance, requiring fluid restriction which often causes thirst and may result in ineffective peripheral perfusion. One non-pharmacological nursing intervention that can be applied is the ice cube sucking technique as part of fluid management. This study aimed to analyze the implementation of education the ice cube sucking technique in improving fluid management and peripheral perfusion in elderly patients with chronic kidney disease. The study used a descriptive case study design with a nursing process approach conducted over three sessions in an elderly patient with chronic kidney disease. The intervention was delivered in three sessions, each lasting approximately 15–20 minutes. The results showed a reduction in thirst complaints, improvement in peripheral perfusion indicated by capillary refill time of less than 2 seconds and warm extremities, as well as increased patient and family ability in managing fluid intake. In conclusion, the ice cube sucking technique are effective nursing interventions in fluid management and improving peripheral perfusion in patients with chronic kidney disease.

Chronic kidney disease is one of the global health problems that requires long-term therapy, one of which is through hemodialysis. According to the World Health Organization (WHO), adherence to treatment and diet is a key factor in improving the quality of life for patients with chronic diseases. An appropriate diet plays an important role in controlling electrolyte levels, fluids, and toxic substances in the body. This study aims to describe the knowledge and dietary compliance of patients undergoing hemodialysis at Santa Elisabeth Hospital Medan in 2025.This research used a descriptive quantitative design with a cross-sectional approach. The sample consisted of 36 patients selected using purposive sampling techniques. The research instrument was a questionnaire developed based on dietary guidelines for hemodialysis patients according to WHO and the Indonesian Ministry of Health standards. The results showed that among the 36 hemodialysis patients, 15 respondents (41.7%) had a good level of knowledge, 14 respondents (38.9%) had a moderate level, and 7 respondents (19.4%) had a low level of knowledge. Regarding dietary compliance, 13 respondents (36.1%) were compliant, 18 respondents (50.0%) were moderately compliant, and 3 respondents (13.9%) were non-compliant. There was a tendency showing that higher knowledge levels were positively correlated with better dietary compliance, in line with WHO’s principle that health education is an essential intervention in managing chronic diseases. This study recommends strengthening ongoing educational programs by healthcare professionals, particularly in delivering accurate and easy-to-understand information about diet management for hemodialysis patients.

Chronic kidney disease is one of the global health problems that requires long-term therapy, one of which is through hemodialysis. According to the World Health Organization (WHO), adherence to treatment and diet is a key factor in improving the quality of life for patients with chronic diseases. An appropriate diet plays an important role in controlling electrolyte levels, fluids, and toxic substances in the body. This study aims to describe the knowledge and dietary compliance of patients undergoing hemodialysis at Santa Elisabeth Hospital Medan in 2025.This research used a descriptive quantitative design with a cross-sectional approach. The sample consisted of 36 patients selected using purposive sampling techniques. The research instrument was a questionnaire developed based on dietary guidelines for hemodialysis patients according to WHO and the Indonesian Ministry of Health standards. The results showed that among the 36 hemodialysis patients, 15 respondents (41.7%) had a good level of knowledge, 14 respondents (38.9%) had a moderate level, and 7 respondents (19.4%) had a low level of knowledge. Regarding dietary compliance, 13 respondents (36.1%) were compliant, 18 respondents (50.0%) were moderately compliant, and 3 respondents (13.9%) were non-compliant. There was a tendency showing that higher knowledge levels were positively correlated with better dietary compliance, in line with WHO’s principle that health education is an essential intervention in managing chronic diseases. This study recommends strengthening ongoing educational programs by healthcare professionals, particularly in delivering accurate and easy-to-understand information about diet management for hemodialysis patients.

Chronic Kidney Disease (CKD) is a structural or functional abnormality of the kidneys that lasts ≥3 months with the criteria of eGFR <60 mL/min/1.73 m² or the presence of kidney damage such as albuminuria and urinary abnormalities (Kidney International, 2024). CKD patients, especially those treated in intensive care units, often experience gastrointestinal disorders such as increased volume of gastric residues. Giving enteral nutrition to patients with NGT can increase the volume of gastric residue which is at risk of causing complications. One of the non-pharmacological interventions that can be carried out is abdominal massage, which is a light massage technique in the abdominal area that can stimulate intestinal peristalsis and improve gastrointestinal motility. The purpose of this case study was to determine the effect of  giving abdominal massage on reducing the volume of gastric residue in CKD patients in the ICU. This scientific paper uses a case study design using abdominal mass therapy. The number of respondents was 3 people, the intervention was carried out for 3 days with a time of 10-15 minutes. The application of abdominal massage therapy in the three respondents showed a decrease in the volume of gastric residue after admixture was carried out  for three consecutive days with an average decrease in the volume of gastric residue, which was 50 cc - 75 cc. Abdominal massage is a safe and effective nonpharmacological nursing intervention to help reduce gastric residue volume and support enteral nutrient tolerance in CKD patients in the ICU.

Chronic Kidney Disease (CKD) is a growing global health concern that significantly affects patients’ quality of life. At Bhakti Asih General Hospital, Tangerang, the number of hemodialysis patients increased by 20.42% and dialysis procedures by 25.06% between 2023 and 2024. Despite this service expansion, preliminary findings revealed that 32% of patients reported poor quality of life, 31% experienced low engagement in care, 34% demonstrated low self-efficacy particularly in dietary and fluid management and 32% faced accessibility barriers. These findings indicate a gap between increased service volume and patient-centered outcomes. This study aimed to analyze the effects of patient engagement and self-efficacy on the quality of life of hemodialysis patients, with healthcare accessibility as a mediating variable. A quantitative cross-sectional design was employed. Active hemodialysis patients were selected using purposive sampling. Data were collected through structured questionnaires and analyzed using Structural Equation Modeling (SEM).The results demonstrated that patient engagement and self-efficacy had significant positive effects on quality of life, both directly and indirectly through accessibility. Accessibility also significantly influenced quality of life and strengthened the relationships between patient engagement, self-efficacy, and quality of life.These findings highlight the importance of integrating patient engagement strategies, strengthening self-efficacy through education, and improving service accessibility to enhance quality of life among hemodialysis patients

Hypertension has become a chronic disease known as the silent killer because it often does not show symptoms but can cause serious complications such as stroke, heart disease, and kidney failure. According to WHO, hypertension is one of the leading causes of death worldwide and its prevalence continues to rise. Sleep disturbances can increase sympathetic nervous system activity and stress hormones, which impact blood pressure elevation. Depression is characterized by prolonged feelings of sadness, loss of interest, and decreased energy. Physiologically, depression can increase stress hormones and cause autonomic nervous system imbalance, leading to elevated blood pressure. To determine the relationship between sleep pattern disturbances and depression levels with blood pressure in hypertensive patients in the outpatient department of RS Permata Medika Semarang. Quantitative research with a correlational design using a cross-sectional approach. The sampling technique used was consecutive sampling with a sample size of 79 respondents. The instruments used are the PSQI questionnaire for sleep pattern disturbances and the DASS-42 for depression levels. Ethics test no 03/EC-LPPM/UWHS/II-2026. Data analysis used the Spearman Rank test. The research results show that there is a significant relationship between sleep pattern disturbances and blood pressure in hypertensive patients (p=0.000; rho=0.826). Respondents with poor sleep patterns mostly have high blood pressure, indicating a very strong and positive relationship, where the worse the sleep pattern, the more uncontrolled the blood pressure tends to be. Additionally, there is a significant relationship between the level of depression and blood pressure (p=0.000; rho=0.808). Respondents with severe and very severe depression mostly have high blood pressure, which means that the higher the level of depression, the more the blood pressure increases or becomes uncontrolled. There is a relationship between sleep pattern disturbances and depression levels with blood pressure in hypertensive patients in the outpatient department of Permata Medika Hospital Semarang.

Hypertension and diabetes mellitus are two highly prevalent non-communicable diseases that often coexist as comorbidities, significantly increasing the risk of cardiovascular complications. The coexistence of these conditions accelerates the onset of atherosclerosis, diabetic nephropathy, and kidney failure, thereby requiring more comprehensive clinical management. One of the key parameters in diabetes management is fasting blood glucose (FBG), which reflects the balance of glucose metabolism after a fasting period. Chronic hyperglycemia is known to contribute to endothelial dysfunction, increased peripheral vascular resistance, and activation of the sympathetic nervous system and renin-angiotensin-aldosterone system, ultimately leading to elevated blood pressure. This study employed a systematic literature review approach, analyzing articles published between 2021 and 2025. Narrative synthesis was conducted across various study designs, including cross-sectional, cohort, and meta-analysis studies. The findings indicate that most studies support a significant association between FBG levels and blood pressure, although some reported varying results. Cohort studies provide stronger evidence that elevated FBG increases the risk of new-onset hypertension. Age, treatment adherence, and lifestyle factors were also identified as confounding variables influencing outcomes. Overall, the evidence highlights that glycemic control through FBG monitoring is essential in managing hypertension among diabetic patients. Multidisciplinary strategies, patient education, and strengthening of primary healthcare services are required to reduce cardiovascular risks. Longitudinal studies are recommended to deepen the understanding of the relationship between FBG and blood pressure and to reinforce the scientific basis for evidence-based clinical interventions.

Chronic kidney disease (CKD) is a global health problem with continuously increasing prevalence and mortality. This condition is characterized by a progressive and irreversible decline in kidney function, which is clinically assessed using the estimated glomerular filtration rate (eGFR) as one of the main parameters for staging and monitoring disease progression. Red blood cell distribution width (RDW) is a hematological parameter that reflects the degree of variation in erythrocyte size. In patients with CKD, elevated RDW levels are often associated with oxidative stress and chronic inflammation, which may accelerate kidney damage and increase mortality risk. To analyze the correlation between RDW and eGFR values in patients with chronic kidney disease at ODSK Hospital, North Sulawesi Province. This study used an analytical observational design with a cross‑sectional approach. It was conducted retrospectively using secondary data from the medical records of CKD patients at ODSK Hospital, North Sulawesi Province, from February 2024 to August 2025. This study used a total sampling method with 189 CKD patients who met the inclusion and exclusion criteria.  Based on Spearman-rank correlation analysis, the p‑value obtained was 0.129 (>0.05). There was no significant relationship between RDW and eGFR values in CKD patients at ODSK Hospital, North Sulawesi.Province.

The increasing prevalence of metabolic syndrome and chronic kidney disease underscores the need for simple, low-cost, and community-applicable screening indicators. This study aimed to evaluate the association between basic anthropometric parameters and blood pressure, metabolic indicators, and renal function among adults in the Badui Luar community. A cross-sectional design was employed involving 41 participants who underwent anthropometric assessment, biochemical measurements, and blood pressure evaluation. Pearson correlation analysis was used to examine linear associations between variables. The results demonstrated that neck circumference exhibited significant correlations with dyslipidemia components, including LDL (r = 0.377), TC/HDL ratio (r = 0.516), and HDL (r = –0.433), indicating cervical adiposity as a strong marker of atherogenic risk. Calf circumference showed protective correlations with fasting glucose (r = –0.352) and eGFR (r = 0.322), suggesting the metabolic relevance of peripheral muscle mass in glycemic regulation and renal status. Body mass index showed a weak correlation with systolic blood pressure (r = 0.149), whereas waist and hip circumferences exhibited mild, clinically insignificant correlations with triglycerides and total cholesterol. Overall, these findings highlight that simple anthropometric measures—particularly neck and calf circumference—may serve as early indicators of cardiometabolic and renal risk in community-based screening. Further longitudinal studies with larger and more heterogeneous populations are required to validate these associations and determine the predictive power of anthropometric indicators.

Non-communicable diseases (NCDs) are chronic health conditions that affect not only physical but also psychological well-being, including increased anxiety. Untreated anxiety can reduce quality of life and treatment adherence. Acupressure, as a form of complementary therapy, offers a safe and non-invasive approach to managing anxiety. This narrative review aims to evaluate the effectiveness of acupressure in reducing anxiety among patients with NCDs. Articles were searched using Google Scholar with keywords such as "acupressure", "anxiety", and various chronic diseases. Six studies with experimental and quasi-experimental designs were selected based on inclusion criteria, involving patients with cancer, chronic kidney disease, and osteoarthritis. The findings consistently demonstrated that acupressure reduced anxiety levels, whether performed by a therapist or self-administered, with commonly used points including ST36, LI4, and PC6. This review concludes that acupressure is an effective complementary therapy that can be incorporated into holistic care strategies for anxiety management in patients with NCDs.

Type 2 Diabetes Mellitus (T2DM) is a global health problem with continuously increasing prevalence, covering the majority of diabetes cases worldwide. Persistent hyperglycemia in T2DM progressively damages the kidneys. Early assessment of kidney function, especially through the examination of urea levels and estimated glomerular filtration rate (eGFR) values, is important to predict CKD prognosis and guide therapeutic intervention. To discover the profile of urea levels and eGFR values in Type 2 Diabetes Mellitus patients at ODSK Hospital, North Sulawesi Province. This study is a descriptive quantitative observational study with a cross-sectional design, conducted retrospectively using secondary data from the medical records of Type 2 Diabetes Mellitus patients at ODSK Hospital, North Sulawesi Province during the period February 2024–August 2025 who met the inclusion criteria. From a total sample of 658 Type 2 Diabetes Mellitus patients, the majority of patients had high urea levels (53.3%). Based on sex, the proportion of high urea levels in males (57.2%) was higher compared to females (50.5%). Meanwhile, the distribution of eGFR values showed that the G1 category was the most frequent (23.9%). However, the majority of other patients (75.1%) were already in categories G2 to G5, which indicates a decrease in kidney function. This decrease in kidney function was slightly more detected in male patients (76.1%) compared to female patients (74.4%). Type 2 Diabetes Mellitus patients at ODSK Hospital, North Sulawesi Province, have high urea levels and the majority have decreased eGFR values.

Chronic Kidney Disease (CKD) is a global health problem with a continuously increasing prevalence and mortality rate. Global data indicates that kidney disorders have affected more than 850 million people, with CKD being one of the leading causes of death. North Sulawesi is recorded as one of the provinces with the highest prevalence of CKD. Blood creatinine is used as the primary marker of kidney function, while hypertension is a comorbidity commonly found in CKD patients and can act as both a cause and a consequence of impaired kidney function. Several studies have reported varying results regarding the relationship between creatinine levels and blood pressure. Purpose to analyze the association between serum creatinine levels and blood pressure in chronic kidney disease patients with hypertension at ODSK Hospital, North Sulawesi Province. Methods the research design used an observational analytic cross-sectional design. This study used an observational analytic cross-sectional design. It was a retrospective study utilizing secondary data from medical records for the period of June 2022 to August 2025. Total sampling method was employed with a sample size of 65 patients who met the inclusion criteria. Based on the Spearman correlation test results, the significance values between creatinine and systolic pressure was 0.685, and between creatinine and diastolic pressure was 0.787 (p-value >0.05). There is no significant correlation between serum creatinine levels and blood pressure in chronic kidney disease patients with hypertension at ODSK Hospital, North Sulawesi Province.

Diabetes Mellitus often causes disorders in other organs, one of which is kidney disorders, commonly known as Diabetic Nephropathy. Diabetic Nephropathy (DN) is a chronic microvascular complication of Diabetes Mellitus, which is the main cause of end-stage kidney disease. Decreased hemoglobin (Hb) levels, or anemia, are very common clinical manifestations found in patients with this impaired kidney function. Pathophysiologically, the decrease in hemoglobin in DN patients is multifactorial, involving absolute or relative erythropoietin (EPO) deficiency due to damage to renal peritubular interstitial cells. As a result, there is a significant disruption of erythropoiesis, which can disrupt the process of red blood cell maturation in the hematopoiesis process. Monitoring hemoglobin levels is a crucial parameter because anemia in this DN population often appears earlier and is more severe than in non-diabetic chronic kidney disease patients. Therefore, early identification of fluctuations in hemoglobin levels is crucial in clinical management to prevent worsening of the systemic condition of patients with Diabetic Nephropathy. This study aims to review Hemoglobin levels in Type 2 Diabetes Mellitus Patients Based on Diabetic Nephropathy Stage in Anemia Screening. The method in this study used Descriptive Analytical with a sample of 47 respondents who met the inclusion criteria. The sampling and research location were conducted at Dr. Wahidin Sudirohusodo Hospital, Makassar. Hemoglobin measurements were measured using Sysmex Series XN-1000 with the Flowcytometry tool method. The results of the study found normal Hb levels (not anemic) in 25 respondents (53.20%), Mild Anemia in 6 respondents (12.80%), Moderate Anemia in 13 respondents (27.60%) and Severe Anemia in 3 respondents (6.40%). From these data, it is known that not all Diabetic Nephropathy patients in this study experienced Anemia.

Chronic kidney disease (CKD) is a growing global health concern that frequently remains undiagnosed until advanced stages. Early detection through simple laboratory screening is essential to prevent disease progression and associated cardiometabolic complications. This community service program aimed to assess kidney function using serum creatinine and estimated glomerular filtration rate (eGFR), while increasing public awareness regarding CKD prevention. A total of 59 participants were included, with a mean age of 39.15 ± 15.39 years (range 16–75 years), predominantly female (74.58%). The mean serum creatinine level was 1.0 ± 0.19 mg/dL, and the mean eGFR was 91.08 ± 20.53 mL/min/1.73 m². Most participants demonstrated normal kidney function (28.8%) or mild decline (21.6%). A progressive reduction in eGFR with increasing age was observed, reflecting the physiological decline in nephron mass and renal perfusion. The program also provided education on kidney-protective practices, including optimal blood pressure control, diabetes management, adequate hydration, and avoidance of nephrotoxic agents. This intervention improved participants’ understanding of CKD risk factors and the importance of regular screening. In conclusion, serum creatinine and eGFR evaluation offer simple, accurate, and practical tools for early CKD detection, supporting promotive–preventive strategies to slow disease progression and enhance quality of life in at-risk populations.

Depression is one of the mental health problems that often arise in patients with chronic diseases, such as diabetes mellitus, hypertension, and chronic kidney failure. This condition not only impacts the patient's quality of life, but also affects the treatment process and the burden on the family. However, mental health literacy in the community is still low, so targeted preventive and curative efforts are needed. The Community Service Program (PKM) aims to improve people's mental health through educational interventions with scientific booklet media that are easy to understand and apply. The activity method is carried out in a participatory manner, including the preparation stage, socialization, educational implementation, and evaluation. Education is provided to the community with a focus on preventing depression through a healthy lifestyle, stress management skills, and early intervention efforts by seeking professional support. Evaluation is carried out through pre-post tests, observations, and group discussions. The results of the activity showed an increase in public knowledge about depression, a change in attitudes to be more open in expressing feelings, as well as practical skills in relaxation, maintaining sleep patterns, and building social support. Participants also better understand the importance of seeking professional help when depressive symptoms are getting worse. The conclusion of this PKM is that the scientific booklet has proven to be effective as a preventive and curative educational intervention medium, and can be an innovative strategy in improving the mental health of people affected by chronic diseases.