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Equitable vaccine distribution is a global issue that has received increasing attention, especially since the increasing need for vaccines in the face of modern pandemics. This study aims to analyze the inequality in vaccine distribution and the factors influencing vaccine hesitancy through a descriptive qualitative approach, utilizing literature studies and supporting data in the form of graphs. The analysis results show that high-income countries have significantly greater access to vaccines than middle- and low-income countries, creating inequalities that impact public health protection. Furthermore, levels of vaccine hesitancy were found to vary across social groups, with adolescents being the group with the highest rate of rejection due to the influence of misinformation and low trust in health institutions. These findings confirm that the success of a vaccination program is determined not only by the availability of equitable distribution but also by public acceptance, which is influenced by social, psychological, and ethical factors. Overall, this study emphasizes the importance of applying bioethical principles such as justice, beneficence, and autonomy in formulating effective and inclusive vaccination policies.

Advances in in vitro fertilization (IVF) technology have expanded the scope of reproductive interventions, from simply addressing infertility to enabling genetic selection of embryos through preimplantation genetic testing (PGT). This advancement not only enables the detection and prevention of severe genetic diseases, but also opens up opportunities for the selection of non-medical traits such as intelligence potential, physical characteristics, or specific polygenic scores, giving rise to the phenomenon of “designer babies.” This development presents complex bioethical issues related to human dignity, social justice, biological safety, and the right of children to have an open future. This paper aims to analyze the ethical issues of selecting non-medical characteristics of embryos in modern IVF through a literature review using a biomedical ethics framework, including the principles of autonomy, beneficence, non-maleficence, and justice. The findings show that the application of technology for non-medical purposes is still fraught with scientific risks, biological uncertainties, the potential for commercialization of humans, and the threat of socio-biological inequality. This analysis emphasizes the need to restrict the use of technology to clear medical indications, increase regulation and governance, and involve the public in policy formulation. Thus, advances in reproductive technology must be accompanied by strict ethical considerations so as not to sacrifice individual dignity and the value of justice in society.

RFID (Radio Frequency Identification)-based biohacking has evolved as a body modification practice that integrates technology directly into human biology. While the practice has historical roots dating back to World War II when RFID was used to identify aircraft, its development toward human implantation began in the late 20th century and has become more widespread with society's increasing reliance on digital technology. Analysis of the principle of beneficence reveals that although RFID implantation can increase user convenience, comfort and security, these benefits are not yet fully supported by adequate scientific evidence regarding long-term safety. Meanwhile, the principle of non-maleficence highlights the risks of infection, tissue damage, interference with radiological examinations, and publications regarding other medical complications resulting from implantation, which is generally performed by non-medical personnel. Through historical, technical, and ethical reviews, this research emphasizes the need for a clearer regulatory framework, increased bioethical literacy, and the involvement of healthcare professionals in implantation to ensure that technological developments do not compromise human safety and well-being

Intensive exploitation of fish for caviar production currently threatens the extinction of sturgeon, one of the ancient fish species. Sturgeon egg harvesting is often carried out in inhumane ways, such as dissecting and killing parent fish, causing the natural sturgeon population to decline. The Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) regulates the international trade of sturgeon and caviar, but weak law enforcement, high market demand, and widespread illegal trade all exacerbate the conservation status of this species. Conversely, caviar aquaculture, often considered an alternative, raises new bioethical issues, including long-term stress on fish, disease spread, decline in animal health, and the risk of hybridization that could threaten the genetic integrity of sturgeon populations. From a bioethical and environmental ethics perspective, it is difficult to justify the consumption of caviar as a luxury commodity at the expense of ecosystem sustainability and animal welfare. Therefore, sturgeon conservation requires a comprehensive approach that includes reducing consumer demand, improving legislation and enforcement, and preserving and restoring sturgeon's natural habitats.

This study examines the bioethical and Sharia dilemmas arising from the production of slaughter-free meat through animal cell culture as a modern food innovation. Concerns regarding the halal status of the cell source, the use of culture media such as Foetal Bovine Serum, and ethical issues related to animal welfare necessitate an in-depth analysis of the halal status and moral implications of this technology. The research method employs a literature study with a descriptive qualitative approach, reviewing journals, books, and contemporary fatwas related to cultured meat, bioethics, and Islamic law. The results indicate that the Sharia aspect heavily depends on the cell source, the medium used, and the culture process, while the bioethical perspective highlights animal welfare, scientific transparency, and the moral responsibility of researchers. Furthermore, the acceptance among Muslim communities is significantly influenced by trust in halal certification bodies and the availability of transparent information. This study affirms the need for biotechnology-based halal standardization and the development of fully halal media and supporting materials to ensure the widespread acceptance of cultured meat in the future.

The phenomenon of cockfighting still persists in various communities in Indonesia as a cultural practice, entertainment, and symbol of certain social identities. However, this practice raises serious issues when analyzed from the perspectives of modern bioethics, animal welfare, public health, and normative religious values, particularly maqāṣid al-sharī‘ah. This study aims to examine the ethical conflicts that arise from cockfighting by analyzing the biological and physiological impacts on animals, violations of animal welfare principles, and tensions between local cultural legitimacy and universal ethical standards. This research uses a descriptive-qualitative approach based on a review of relevant scientific literature, including national and international publications in the fields of bioethics, animal welfare, animal health, and law. The results of the study show that cockfighting systematically causes severe physical injury, extreme biological stress, behavioral disorders, and an increased risk of zoonotic disease transmission, so it can be categorized as a form of organized animal cruelty. From a bioethical and maqāṣid al-sharī‘ah perspective, this practice contradicts the principles of respect for life, non-maleficence, and protection of life and public welfare. The lack of legal protection focused on animal welfare reinforces the urgency of a transformative approach through regulatory reformulation, public education, and the development of non-violent cultural alternatives. This study is expected to serve as a scientific and ethical basis for policy formulation and contextual and sustainable animal protection efforts.  

Islamic law faces significant challenges from the rapid advancements in bioethics and artificial intelligence (AI). The current responsive approach, based on ad-hoc fatwas, is deemed inadequate to address the systemic ethical dilemmas posed by these disruptive technologies. This research aims to propose a proactive and systematic ijtihad framework capable of anticipating and guiding technological innovation to align with the higher objectives of Shari'ah (Maqasid al-Shari'ah). Using a qualitative, library-based method with a juridical-normative and philosophical approach, this study analyzes primary and secondary Islamic legal sources through the Maqasid al-Shari'ah theoretical framework. The research finds the current model to be limited and, as a solution, offers a novelty in the form of the Hierarchical Model of Technological Ijtihad (HI-Tech). This model is a structured, interdisciplinary reasoning process, supported by a proposed institution, the Bio-Artificial Ijtihad Council (MIBA), and a digital platform, "Nur-Fatwa," for dissemination. The implication of these findings is the need for a paradigm shift for Islamic legal institutions towards an anticipatory, interdisciplinary, and institutionalized approach to address contemporary technological issues, thereby ensuring the continued relevance of Islamic law.

The study explores the application of bioethical aspects in the use of botanical pesticides for pest prevention in the environment at the Horticultural Seed Development Unit (UPT) under the Department of Agriculture and Fisheries. Utilizing a qualitative approach with quantitative elements, this research aims to deepen understanding regarding bioethical practices in botanical pesticide usage and evaluate its effectiveness in controlling pests. The population consists of employees and students involved in pesticide-related activities, selected through purposive sampling to ensure knowledgeable respondents. Key variables include the independent variable of botanical pesticide application and dependent variables such as pest population reduction, environmental impact, and the presence of beneficial non-target organisms like pollinators. The descriptive qualitative method combined with survey techniques provides insights into how bioethical principles are integrated into pest control strategies, promoting sustainable agricultural practices. This research contributes to advancing environmentally friendly pest management solutions while maintaining ecological balance.

Current water safety issues in society are very diverse. Water quality safety issues are closely related to the bioethics of water testing, because water testing involves protecting human health and the environment. Water quality testing is an important part of ensuring that the water consumed is safe for human health. The purpose of this study was to evaluate the application of bioethical principles in water quality testing (Pb and Cd). This study was conducted in March 2025 at the UPT Food Security Laboratory of Medan City. The data analysis used in this study used qualitative descriptive methods to see the pattern of observation responses. The results of the study showed that in the bioethical aspect of sample testing, analysts who conducted the testing had implemented bioethics or SOPs that apply in food quality and safety testing laboratories. In conducting water testing for lead and cadmium examination, the procedures used were in accordance with applicable requirements using testing procedures from SNI (Indonesian National Standard).

Bioprinting 3D merupakan suatu teknologi transformatif dalam konstruksi rekayasa jaringan dan prototipe organ untuk meniru karakteristik jaringan alami yang digunakan dalam pengobatan regeneratif. Secara bioetika, organ tiruan 3D melibatkan analisis dan evaluasi tentang implikasi moral, sosial, dan hukum dari penggunaan teknologi. Metode yang digunakan dalam penelitian ini adalah systematic literature review dengan menyajikan gambaran yang komprehensif tentang pengembangan dan pemanfaatan teknologi organ tiruan 3D (bioprinting) dalam perspektif bioetika dan hukum islam. Hasil menunjukkan bahwa bioprinting 3D memiliki pengaplikasian yang sangat beragam, diantaranya dalam bidang medis contohnya model untuk studi penyakit dan uji obat, pengobatan regeneratif, pembentukan organoid dan jaringan khusus, dan masih banyak lagi. Aspek bioetika mengenai bioprinting 3D masih menimbulkan tantangan yang perlu dipertimbangkan. Masalah bioetika seperti sumber atau asal bahan yang digunakan dalam bioprinting masih menjadi permasalahan. Penggunaan sel punca embrionik masih kontroversial, karena melibatkan penghancuran embrio manusia, sehingga menimbulkan pertanyaan moral dan etika mengenai nilai dan kesucian hidup manusia. Dalam perspektif Islam, berdasarkan analisis dari Al-Quran, hadits, dan beberapa fatwa, produksi organ tubuh melalui metode cetak 3D disarankan untuk dikategorikan sebagai perubahan ciptaan Tuhan yang dibolehkan karena tujuannya untuk mengobati dan menyelamatkan nyawa atau khusus untuk penggunaan proses transplantasi organ.

With the rapid increase in global population and the ongoing depletion of agricultural land, food security faces an escalating threat. CRISPR genetic engineering technology offers immense potential to enhance crop resilience and productivity. However, its application raises significant ethical concerns, both from a bioethical perspective and within the framework of Islamic values. This article examines core principles of bioethics and Islamic ethics to explore the morally conscious integration of genetic technology. Through a comprehensive literature review, it underscores the necessity of a collaborative approach involving scientists, policymakers, and religious leaders to establish ethical guidelines for its responsible use. The findings highlight the critical need to strike a balance between technological innovation and the preservation of moral principles. By adhering to ethical standards rooted in both modern bioethics and Islamic teachings, genetic technologies such as CRISPR can be harnessed to address food security challenges by improving crop productivity and fortifying resistance to diseases and extreme environmental stressors, without compromising moral integrity.